• Title/Summary/Keyword: ATL

Search Result 41, Processing Time 0.023 seconds

Plasma Soluble CD30 as a Possible Marker of Adult T-cell Leukemia in HTLV-1 Carriers: a Nested Case-Control Study

  • Takemoto, Shigeki;Iwanaga, Masako;Sagara, Yasuko;Watanabe, Toshiki
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.18
    • /
    • pp.8253-8258
    • /
    • 2016
  • Elevated levels of soluble CD30 (sCD30) are linked with various T-cell neoplasms. However, the relationship between sCD30 levels and the development of adult T-cell leukemia (ATL) in human T-cell leukemia virus type 1 (HTLV-1) carriers remains to be clarified. We here investigated whether plasma sCD30 is associated with risk of ATL in a nested case-control study within a cohort of HTLV-1 carriers. We compared sCD30 levels between 11 cases (i.e., HTLV-1 carriers who later progressed to ATL) and 22 age-, sex- and institution-matched control HTLV-1 carriers (i.e., those with no progression). The sCD30 concentration at baseline was significantly higher in cases than in controls (median 65.8, range 27.2-134.5 U/mL vs. median 22.2, range 8.4-63.1 U/mL, P=0.001). In the univariate logistic regression analysis, a higher sCD30 (${\geq}30.2U/mL$) was significantly associated with ATL development (odds ratio 7.88 and the 95% confidence intervals 1.35-45.8, P = 0.02). Among cases, sCD30 concentration tended to increase at the time of diagnosis of aggressive-type ATL, but the concentration was stable in those developing the smoldering-type. This suggests that sCD30 may serve as a predictive marker for the onset of aggressive-type ATL in HTLV-1 carriers.

Shear Bond Strength of Composite Resin ($TESCERA^{TM}$ ATL) Veneering on Zirconia Surface with Various Surface Treatments (지르코니아의 표면처리 방법에 따른 압축강화형 복합레진 ($TESCERA^{TM}$ ATL)전장의 결합강도)

  • Park, Soo-Jeong;Lee, Richard Sung-Bok;Lee, Suk-Won;Ahn, Su-Jin;Lim, Ho-Nam
    • Journal of Dental Rehabilitation and Applied Science
    • /
    • v.27 no.1
    • /
    • pp.1-13
    • /
    • 2011
  • The aim of this study was to evaluate shear bond strength of pressed reinforced composite resin ($TESCERA^{TM}$ ATL) veneering to zirconia with various surface treatments. Forty sintered zirconia specimens and forty pockmarked zirconia specimens were fabricated. All the materials were categorized as Group 1 (Control : porcelain veneering on zirconia surface), Group 2 ( $TESCERA^{TM}$ ATL dentine veneering after bonding agent application on zirconia surface), Group 3 ($TESCERA^{TM}$ ATL dentine veneering on pockmarked zirconia surface), Group 4 ($TESCERA^{TM}$ ATL dentine veneering after bonding agent application on pockmarked zirconia surface), Group 5 (Thermocycling on Group 1), Group 6 (Thermocycling on Group 2), Group 7 (Thermocycling on Group 3), and Group 8 (Thermocycling on Group 4). SBS(Shear bond strength) of 8 groups was determined with an Instron Universal Testing Machine. Also fractured surface of specimens were observed with a scanning electron microscope. There were no significant differences in the initial SBS between Group 1(control group), Group 3, and Group 4. (p>0.05) Group 2 presented the lowest SBS values. There was a no significant difference between just as 24hour water storage and simulated aging on pockmarked zirconia groups. (p>0.05) A formation of pockmarked irregularities on zirconia surface as mechanically pitted surface was reliable method for establishing a stronger bond between $TESCERA^{TM}$ ATL and zirconia-based material.

Development of Applications using Java OR ATL Web Services (Java와 ATL 웹 서비스를 이용한 애플리케이션 개발)

  • 김병규;박우전
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2002.10e
    • /
    • pp.175-177
    • /
    • 2002
  • 웹 서비스는 기존의 컴포넌트를 대체할 새로운 기술이지만 그 유용성에 비해 아직 사용예가 많지 않고 개발할 때의 장단점이나 문제점도 많이 알려지지 않았다. 본 논문에서는 웹 서비스를 이용한 웹 3D뷰어를 개발하여 웹 서비스 개발방법과 이점을 알아내고 앞으로의 개발 방향 등을 논할 것이다.

  • PDF

Control of the frame grabber using ATL COM Object in the Web (ATL COM 객체를 이용한 웹 상 Frame Grabber 제어)

  • Shin, Hae-Sang;Kim, Seong-Hoon;Yang, Jin-Young;Kim, Jong-Hwa
    • Proceedings of the Korea Information Processing Society Conference
    • /
    • 2001.10a
    • /
    • pp.677-680
    • /
    • 2001
  • 본 논문은 컨트롤러의 유무와 상관없이 네트워크에 응용장치들을 인터페이스 제어하는 방법에 관련된 연구로서, ATL COM 객체를 이용하여 웹에 인터페이스되어 있는 CCD의 Frame Grabber를 원격으로 제어하여 클라이언트에 처리결과인 CCD 영상을 전송하는 절과를 얻어 서버에 종속되어 있는 모든 장치를 원격에서 제어할 수 있는 가능성을 확인하였다.

  • PDF

Implementation of 3D+Temporal Object Components Using ATL/COM (ATL/COM을 이용한 3차원+Temporal 객체 컴포넌트 구현)

  • Lee, Hyun-Ah;Lim, Hun-Ki;Nam, Kwang-Woo;Ryu, Keun-Ho;Lee, Jong-Hun
    • Proceedings of the Korea Information Processing Society Conference
    • /
    • 2001.04a
    • /
    • pp.69-72
    • /
    • 2001
  • CIS 기술 그룹과 데이터베이스 그룹간의 상호 연관된 연구의 필요성이 인식되면서, 시공간의 개념에 대한 동시 지원이 요구되고 있다. 또한 각 시스템간의 데이터 모델이 매우 다르기 때문에 지금까지 분산되어 있던 방대한 양의 공간 데이터에 대한 상호 운용성의 필요성이 증가함에도 불구하고 시스템의 통합 및 표준화의 진행이 어렵다. 이 논문에서는 분산된 공간 데이터의 상호 운용성을 제공하고 공간과 시간의 개념을 동시에 지원하기 위해 3차원 시공간 컴포넌트를 설계하고 이를 ATL/COM 을 사용하여 구현함으로써 COM 컴포넌트의 장점인 확장성과 재사용성을 그대로 수용하였다. 상호 운용성을 위한 통합 데이터 모델로써 OGC 의 2차원 표준 모델을 3차원과 시간 영역으로 확장시키고, 이를 기반으로 COM 컴포넌트 인터페이스를 설계하였다. 또한 공간 데이터를 WKB 구조로 정의하여 저장함으로써 시스템간의 이식성을 보장한다.

  • PDF

Purification and Characterization of a Lectin from Arisaema tortuosum Schott Having in-vitro Anticancer Activity against Human Cancer Cell Lines

  • Dhuna, Vikram;Bains, Jagmohan Singh;Kamboj, Sukhdev Singh;Singh, Jatinder;Shanmugavel;Saxena, Ajit Kumar
    • BMB Reports
    • /
    • v.38 no.5
    • /
    • pp.526-532
    • /
    • 2005
  • A lectin with in-vitro anticancer activity against established human cancer cell lines has been purified by affinity chromatography on asialofetuin-linked amino activated silica beads from the tubers of Arisaema tortuosum, popularly known as Himalayan Cobra lily, a monocot plant from the family Araceae. The bound Arisaema tortuosum lectin (ATL) was eluted with glycine-HCl buffer, pH 2.5. ATL was effectively inhibited by asialofetuin, a complex desialylated serum glycoprotein as well as by N-acetyl-D-lactosamine, a disaccharide. It gave a single band corresponding to a subunit molecular weight of 13.5 kDa in SDS-PAGE, pH 8.8 both under reducing and non reducing conditions. When subjected to gel-filtration on Biogel P-200, it was found to have a molecular weight of 54 kDa, suggesting a homotetramer structure, in which individual polypeptides are not bound to each other with disulfide bonds. ATL is a glycoprotein with 0.9% carbohydrate content, stable up to $55^{\circ}C$ and at pH 2 to 10. The lectin had no requirement for divalent metal ions i.e. $Ca^{2+}$ and $Mn^{2+}$ for its activity. However, as reported for other monocot lectins, ATL gave multiple bands in isoelectric focusing and Native PAGE, pH 8.3. The lectin was found to inhibit in vitro proliferation of human cancer cell lines HT29, SiHa and OVCAR-5.

ATL 1.0: An Artificial Intelligence Technology Level Definition (ATL 1.0: 인공지능 기술 수준 정의)

  • Min, O.G.;Kim, Y.K.;Park, J.Y.;Park, J.G.;Kim, J.Y.;Lee, Y.K.
    • Electronics and Telecommunications Trends
    • /
    • v.35 no.3
    • /
    • pp.1-8
    • /
    • 2020
  • Artificial-intelligence (AI) technology is used in a variety of fields, from robot cleaner motion control to call center counselors, AI speakers, and Mars exploration. Because the technology levels of all applications and services that utilize AI vary widely, it is not possible to view all applications using AI technology at the same level. Nevertheless, there have been no cases in which the level of AI technology was defined. Therefore, the Electronics and Telecommunications Research Institute (ETRI) Artificial Intelligence Research Laboratory has defined the levels of the main technical elements of AI from steps 1 to 6. In this report, the Artificial Intelligence Technology Level 1.0 (ATL 1.0) is presented. It was established by comprehensively referring to the AI technology prospects and technology roadmaps of major countries. It is hoped that it can be used as a measure for determining the levels of AI applications or services or as an indicator for establishing a technology roadmap.

Development of the Eggs, Larvae and Juveniles by Artificially-Matured Pacific Mackerel, Scomber japonicus in the Korean Waters (성숙 유도한 한국산 고등어 (Scomber japonicus)의 난발생과 자치어의 형태 발달)

  • Kim, Dae-Hyun;Kim, Dae-Jung;Yoon, Seong-Jong;Hwang, Hyung-Gue;Kim, Eung-Oh;Son, Sang-Gyu;Kim, Jin-Koo
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.41 no.6
    • /
    • pp.471-477
    • /
    • 2008
  • Development of egg, larvae and juveniles for the Pacific mackerel, Scomber japonicus are described following natural fertilization in the indoor tank of $25^{\circ}C$ water temperature. Following a routine hormone treatment technique for the brood stock, male and female mackerels were artificially matured by intramuscular injections of LHRHa at a dosage of $400{\mu}g/kg$ body weight (BW)+Domperidone at a dosage of $4{\mu}g/kg$ body weight (BW) to induce maturation in a separate aquarium and induced natural spawning. Fertilized eggs were ca. 1.0 mm in diameter; spherical in shape with a single oil globule; pelagic and non-adhesive. Hatching occurs 41 hours after fertilization at $23-24^{\circ}C$. The newly hatched larvae was 3.03 mm in average total length (ATL), the mouth and anus were not open, oil globule located in posterior end of yolk sac, and preanal length was 42.8% of TL. The larvae measuring 2.89 mm ATL, almost absorbed yolk sac and oil globule material in 2 days after hatching, in which the mouth and anus were open. Melanophores, branch or star in shape were observed on the top of head, peritoneal region and along the ventral contour. In 13 days after hatching, the larvae was 6.88 mm ATL, its posterior end of notochord began to flex upward, finfold of caudal fin appeared, jaw teeth were already formed. In 19 days after hatching, the larvae was 7.71 mm ATL completed only caudal fin rays (9+8), and preanal length was 49.4% of TL. In 37 days after hatching, the larvae was 27.4 mm ATL already completed all the fins, and preanal length was 59.9% of TL.

Development of Windows Mobile Applications using Model Transformation Techniques (모델 변환 기법을 활용한 윈도우즈 모바일 어플리케이션 개발)

  • Kim, Woo-Yeol;Son, Hyun-Seung;Kim, Jae-Seung;Kim, R. Young-Chul
    • Journal of KIISE:Computing Practices and Letters
    • /
    • v.16 no.11
    • /
    • pp.1091-1095
    • /
    • 2010
  • The existing smart-phone software is dependent on the platform, which should be developed per each different platform, Each vendor will develop its own platform such as Apple's Cocoa platform, Google Android, Microsoft Windows Mobile, etc. In this paper, we apply model transformation technique for developing heterogenous software at a time in heterogenous smart phone area. This approach separates the independent model and dependent model. and automatically transforms the difference between them with model transformation language. To execute model transformation, it is required with meta model, model transformation language. In this paper, we are applied to smart-phones as follows: model will be UMLmodel, metamodel be UML metamodel, and choose ATL as Model transformation language. We show examples of the Windows Mobile platform environment to be developed using model transformation. As a result, if we use platform-independent model in this paper and redefine model transformation rules for the iPhone or Android, it will be automatically transformed into heterogenous platforms.

The evaluation of color and color difference according to the layering placement of Incisal shade composites on the body composites of the indirect resin restoration (간접 수복용 복합레진의 Incisal 색상 적층 두께에 따른 표면 색상 및 색차의 평가)

  • Park, Su-Jung;Lee, Han-Young;Nah, Myong-Yun;Chang, Hoon-Sang;Hwang, Yun-Chan;Oh, Won-Mann;Hwang, In-Nam
    • Restorative Dentistry and Endodontics
    • /
    • v.36 no.1
    • /
    • pp.37-49
    • /
    • 2011
  • Objectives: The aim of this study was to evaluate the surface color of indirect resin restoration according to the layering placement of different shade of incisal composite. Materials and Methods: In this study, CIE $L^*a^*b^*$ value of 16 Body composite of Tescera ATL (Bisco, Schaumburg IL,USA) was measured by spectrophotometer (NF999, Nippon Denshuku, Japan), and compared to CIE $L^*a^*b^*$ value of Vitapan shade guide. Nine shade Incisal composite of Tescera ATL were buildup to 1 mm thickness on Body composites inlay block, and CIE $L^*a^*b^*$ value was measured. Incisal composite was ground to 0.5 mm thickness and CIE $L^*a^*b^*$ value was re-measured. Color difference between Body composite and Incisal composites layered on Body composite was calculated as a function of thickness. Results: Color difference between corresponding shade of Tescera Body composite and Vitapan shade guide was from 6.88 to 12.80. $L^*$ and $b^*$ value was decreased as layering thickness of Incisal composite on Body composite was increased. But, $a^*$ value did not show specific change tendency. Conclusions: Surface color difference between Body composites and Incisal composites layered on Body composite was increased as the layering thickness of Incisal composite increased (p < 0.05).