• Title/Summary/Keyword: APV

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Murine susceptibility to Avian pneumovirus (APV) of turkey origin (칠면조에서 분리된 Avian pneumovirus(APV)의 쥐의 감염성에 대한 연구)

  • Shin, Hyun-Jin
    • Korean Journal of Veterinary Research
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    • v.41 no.4
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    • pp.529-533
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    • 2001
  • The infectivity of an isolate of avian pneumovirus (APV) from turkeys to Balb/c mice was investigated to examine the transmission possibility to mammals. Three different age groups (3, 5 and 7 weeks old) were exposed by oculonasal route with a cell cultured APV of turkey origin. No clinical signs were observed from both APV-inoculated and commingled mice. However, all the tissue samples including blood from mice in the APV-inoculated group were positive for APV by polymerase chain reaction (PCR) up to 6 days postinoculation. At 14 days postinoculation, APV was not detected from blood samples by PCR, but sera showed the presence of APV-specific antibodies. In commingled mice, APV was detected from lung and rectal swap samples by PCR. These results suggest that an APV isolate from turkey could be transmitted to mice by direct contact or other ways.

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Persistent Infection of Avian Pneumovirus (APV) in Turkeys (칠면조에서 Avian Pneumovirus(APV)의 지속 감염에 대한 연구)

  • Shin, Hyun-jin
    • Korean Journal of Veterinary Research
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    • v.41 no.4
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    • pp.523-528
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    • 2001
  • The persistent infection of avian pneumovirus (APV) was studied in turkeys. After APV infection to turkeys, healthy birds were transferred to infected birds and commingled at 4 days, 3 weeks, 6 weeks, 9 weeks, and 15 weeks post-infection. The genome of APV was detected up to 10 days from two birds transferred and commingled with infected birds at 3 weeks post-infection. A bird transferred at 6 weeks post-infection was positive in RT-PCR detection after 5 days. From then on, no bird showed positive results of persistency of APV infection. These findings suggest that persistent APV infection may spread to the healthy birds from the infected birds until several weeks.

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A Comparative Study on Over-The-Tops, Netflix & Amazon Prime Video: Based on the Success Factors of Innovation

  • Song, Minzheong
    • International journal of advanced smart convergence
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    • v.10 no.1
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    • pp.62-74
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    • 2021
  • We compare Over-the-Tops (OTTs), Netflix and Amazon Prime Video (APV) with five success factors of innovation. Firstly, Netflix offers better personalized service than APV, because APV has collaborative filtering algorithms to recommend safe bets, not the customers really want. Secondly, APV' user interface is undercooked to lock the members in, even if it has more content and better price offer than Netflix retaining its loyal customers despite the price increase. Thirdly, Netflix has simple subscription model with three tiering, but APV has complicated pricing model having annual and monthly, APV and Prime Video (AV) app, Amazon subscription and extra payment of Amazon Prime Channels (APCs). Fourthly, Amazon has fewer partnership than Netflix especially when it comes to local TV series. Instead, Amazon has live TV channel collaboration including sports content. Lastly, both have strategic and operational agility in their organization well.

An Empirical Study on the Instrument Approach Procedure for Satellite Based Augmentation System (SBAS) APV-I (위성기반보정시스템(SBAS) APV-I 계기접근절차에 관한 실증 연구)

  • Yang, Yoonsung;Choi, Sangil;Kim, Hyeonmi;Kim, Huiyang
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.30 no.1
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    • pp.28-37
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    • 2022
  • Along with the remarkable advances in GNSS technology, SBAS further enhances the accuracy and integrity of GNSS location information and derives improvement in the safety and efficiency of air traffic management from reducing GNSS location errors, induced by passing through the ionosphere and atmosphere, to less than three meters. In this regard, ICAO specifies the standards of SBAS signals and recommends every party to phase in by 2025; and it is foreseeable that SBAS APV-I and CAT-I will be provided in South Korea by its undertaking the development of KASS, a Korean SBAS. The purpose of the study is to design SBAS APV-I procedure on the basis of the runway 15L of Incheon International Airport and conduct obstacle assessment according to PAN-OPS Doc. 8168, focusing on the usability and usefulness of SBAS APV-I. The results show that SBAS APV-I will provide better decision height compared to other PBN RNP approach procedures such as LNAV and Baro-VNAV at the Incheon International Airport.

Examination of seroprevalence and detection of Avian pneumovirus from layer hens in Gyeongbuk province (경북지역 산란계에서 Avian pneumovirus에 대한 항체가 및 바이러스 검출 조사)

  • Kim, Jung-Eun;Hwang, Ji-Young;Bae, Dong-Rok;Sung, Myoung-Suk;Kim, Soon-Tae;Kim, Sang-Yun
    • Korean Journal of Veterinary Service
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    • v.30 no.1
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    • pp.43-49
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    • 2007
  • Avian pneumovirus(APV), also known as avian rhinotracheitis(ARTV), affects both turkeys and chickens and is known to be the primary causative agent of turkey rhinotracheitis(TRT). The aim of this study was to establish the presence or absence of antibodies to APV by an enzyme-linked immunosorbent assay(ELISA) and confirm APV by a reverse transcriptase-polymerase chain reaction(RT-PCR). The tested serum and feces were collected from laying hens in Gyeongbuk province. The positive farms with antibody against APV by ELISA were 90(96.7%) of 93 and positive serum samples were 433(93.1%) of 465 different sera. By regional group, sera from Uiseong, Cheongsong and Bonghwa were noted as 100% positive and positive rates of samples from Yeongju, Andong and Yeongyang were 93.3%, 85.7% and 50%, respectively. However, APV was not detected in feces samples by RT-PCR.

First detection of avian polyomavirus by PCR from Alexandrine Parakeet (Psittacula eupatria) in Korea (대본청 앵무(Psittacula eupatria )로부터 PCR에 의한 avian polyomavirus 최초 검출)

  • Kim, Hee-Jung;Lee, Sun-Rock;Park, Choi-Kyu
    • Korean Journal of Veterinary Service
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    • v.37 no.3
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    • pp.213-218
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    • 2014
  • In early April 2014, a month-old Alexandrine Paraqeet (Psittacula eupatria) that was raised in a domestic aviary located in Gyungju-si, Korea was suddenly died and submitted to Animal Disease Intervention Center, Kyungpook National University in order to diagnose the causative agent. In post-mortem examination, the bird had abnormally developed feathers on the neck and abdomen region and subcutaneous hemorrhages on the neck and cheek adjacent to the beak. At necropsy, the bird had hemorrhage on the muscle of the femoral region, ascites, multi-focal hemorrhages on the epicardium, and diffuse hemorrhages on the sub-serosa of proventriculus and gizzard, suggesting typical avian polyomavirus (APV) infection. The partial large tumor (T) antigen gene of APV was detected by PCR from tissues of the heart, lung, liver, kidney, proventriculus and feathers of the APV-suspected birds. However, other pathogenic virus-specific nucleic acid common with psittacine birds such as avian bornavirus, psittacine beak and feather disease virus and psittacid herpesvirus were not detected from the mixed tissue samples of the bird, indicating this case is due to single infection of APV. Nucleotide sequence analysis of the partially amplified large T antigen DNA was confirmed to have 99~100% homology with that of the previously reported APV strains. This case report describes the first detection of APV in Alexandrine Paraqeet in Korea.

Serological survey of avian pneumovirus infection in laying hens of Gyeongbuk province (경북지역 산란계에서 avian pneumovirus 에 대한 항체가조사)

  • 김순태;김성국;조민희;김영환
    • Korean Journal of Veterinary Service
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    • v.26 no.1
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    • pp.51-56
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    • 2003
  • Avian pneumoviros(APV), also known as avian rhinotracheitis virus(ARTV), affects both turkeys and chickens and is known to be the primary causative agent of turkey rhinotracheitis (TRT). The aim of this study was to establish the presence or absence of antibodies to avian pneumovirus in the commercial poultry population of Korea. For this purpose, chicken serum samples were obtained and tested by an enzyme-linked immunosorbent assay (ELISA). The tested serum was collected in laying hens with reduction of egg production or normal in Gyeongbuk province. A total of 184 sera representing 42 different poultry farms of the Gyeongbuk region of Korea were included in this study. Laying hens of 16 different farms with reduction of egg production and laying hens of 26 different farms with clinically healthy at the time of serum sampling were considered positive to antibody against APV. In the farms with reduction of egg production, positive farm to antibody against avian pneumovirus were 11 of 16 different farms(68.8%) and positive sera were 47(58.8%) of 80 different serum. In the farms with clinically healthy flock, positive farm to antibody against avian pneumovirus were 12(46.2%) of 26 different farms and positive serum sample were 39(37.5%) of 104 different sera. According to the results tested to 42 different farms in 14 city, 8 of 14 city have flocks with antibody positive laying hens against APV, 1 of 14 city have antibody suspicious and 5 of 14 city shown antibody negative, respectively.

Effect of NMDA receptor antagonist on Osteoblasts Damaged by Methylmercuric Chloride (메틸수은으로 손상된 골모세포에 대한 NMDA 수용체길항제의 영향)

  • Ha Dae Ho;Yang Hyun Woong;Lee Joung Hwa;Lee Kang Chag
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.2
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    • pp.412-415
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    • 2003
  • In order to elucidate the mechanism between cytotoxicity of methhylmercuric chloride(MMC) and oxygen radicals in cultured osteoblasts of neonatal mouse, cell viability was measured by MTT assay in osteoblasts treated with 1~50 μM MMC for 30 hours. And also, the protective effect of N-methyl D-aspartate(NMDA) receptor antagonist, D-2-amino-5-phosphovaleric acid(APV) was examined by cell viability in these cultures. Cell viability was significantly decreased in dose dependently after exposure of 30 μM MMC to cultured osteoblasts for 30 hours. Protective effect of APV against MMC-mediated toxicity was very effective in these cultures. From above the results, it suggests that MMC is toxic in cultured mouse osteoblasts and NMDA receptor antagonist such as APV is effective in blocking the osteotoxicity induced by MMC.

Protective Effect of NMDA Receptor Antagonist on the Neurotoxicity Induced by Lead as an Environmental Pollutant (환경오염원인 납의 신경독성에 대한 NMDA 수용체 길항제의 보호 효과)

  • Kim, Young-Wo;Rim, Yo-Sup;Seo, Young Mi
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.3
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    • pp.193-200
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    • 2017
  • Objectives: This study was performed to evaluate the neurototoxicity of the environmental pollutant lead acetate(LA) and the protective effect of the D-2-amino-5-phosphonovaleric acid(APV), N-methyl-D-aspartate(NMDA) receptor antagonist on LA-induced cytotoxicity in cultured C6 glioma cells. Materials and Methods: For this study, cell viability in cultured C6 glioma cells was assessed by XTT assay and antioxidative effect, such as lactate dehydrogenase(LDH) activity, by LDH detection kit. Results: LA significantly decreased cell viability in a dose-dependent manner, and the XTT50 value was determined to be 33.3 uM of LA. The cytotoxicity of LA was deemed highly toxic according to Borenfreund and Puerner's toxic criteria. The vitamin E antioxidant significantly increased cell viability damaged by LA-induced cytotoxicity in these cultures. For the protective effect of APV on LA-induced cytotoxicity, APV significantly increased not only cell viability, but also inhibition of LDH activity. From these results, it is suggested that oxidative stress is involved in the neurotoxicity of LA, and APV effectively protected against LA-induced cytotoxicity via an antioxidative effect as an inhibotory activity of LDH. Conclusions: Natural resources like APV may be putative therapeutic agents for the toxic diminution of environmental pollutants such as LA correlated with oxidative stress.

A Decision Support System for Smart Farming in Agrophotovoltaic Systems (영농형 태양광 시스템에서의 스마트 농업을 위한 의사결정지원시스템)

  • Youngjin Kim;Junyong So;Yeongjae On;Jaeyoon Lee;Jaeyoon Lee
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.45 no.4
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    • pp.180-186
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    • 2022
  • Agrophotovoltaic (APV) system is an integrated system producing crops as well as solar energy. Because crop production underneath Photovoltaic (PV) modules requires delicate management of crops, smart farming equipment such as real-time remote monitoring sensors (e.g., soil moisture sensors) and micro-climate monitoring sensors (e.g., thermometers and irradiance sensors) is installed in the APV system. This study aims at introducing a decision support system (DSS) for smart farming in an APV system. The proposed DSS is devised to provide a mobile application service, satellite image processing, real-time data monitoring, and performance estimation. Particularly, the real-time monitoring data is used as an input of the DSS system for performance estimation of an APV system in terms of production yields of crops and monetary benefit so that a data-driven function is implemented in the proposed system. The proposed DSS is validated with field data collected from an actual APV system at the Jeollanamdo Agricultural Research and Extension Services in South Korea. As a result, farmers and engineers enable to efficiently produce solar energy without causing harmful impact on regular crop production underneath PV modules. In addition, the proposed system will contribute to enhancement of the smart farming technology in the field of agriculture.