• Biomolecules & Therapeutics
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• v.1 no.1
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• pp.98-102
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• 1993

The therapeutic effectiveness of adenine arabinoside(tora-A) and its conjugate of prednisone(BR-8702-AP) was compared in Herpes simplex Virus Type 1 (HSV-1) infected BALB/C mice. The BALB/C mouse was infected with HSV-1(700 PFU/mouse) intranasally. Among mice infected intranasally with virus, a mortality rate of 100% was observed. On the oral administration of non-toxic doses of ara-A or BR-8702-AP(125 mg /kg/day) for 5 consecutive days 2 hours after virus infection, the tora-A was highly effective in reducing mortality to 0% (P<0.001) and BR-8702-AP was also effective in reducing mortality to 15% (P<0.01). In this model infection, the virus was first replicated in the lung and transmitted to the brain. Both arts-A and BR-8702-AP did not inhibit the viral replication in the lung, but they inhibited the viral transmission to the brain. However, the BR-8702-AP was less effective than the aria-A to prevent transmission of virus to brain. Therefore, the reduced mortality due to tora-A or BR-8702-AP therapy was associated with inhibition of viral transmission to brain.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.12
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• pp.52-60
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• 2010

Knowledge of the physical locations of access point of WLAN is becoming increasingly important with the rise of location-based services. In this article, we propose a new AP localization method using neural network approach. Basic theory and properties are derived for precise outdoor AP localization using GPS location information and RSSI. Rules for neural network model are derived and simulation has finally been done to demonstrate the efficiency of the proposed method. The simulation results show that the proposed method can result in AP localization with very. low error probability.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.5
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• pp.1951-1972
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• 2018

Wi-Fi Access Point (AP) optimization approaches are used in indoor positioning systems for signal coverage enhancement, as well as positioning precision improvement. Although the huge power consumption of the AP optimization forms a serious problem due to the signal coverage requirement for large-scale indoor environment, the conventional approaches treat the problem of power consumption independent from the design of indoor positioning systems. This paper proposes a new Fast Water-filling algorithm Group Power Constraint (FWA-GPC) based Wi-Fi AP optimization approach for indoor positioning in which the power consumed by the AP optimization is significantly considered. This paper has three contributions. First, it is not restricted to conventional concept of one AP for one candidate AP location, but considered spare APs once the active APs break off. Second, it utilizes the concept of water-filling model from adaptive channel power allocation to calculate the number of APs for each candidate AP location by maximizing the location fingerprint discrimination. Third, it uses a fast version, namely Fast Water-filling algorithm, to search for the optimal solution efficiently. The experimental results conducted in two typical indoor Wi-Fi environments prove that the proposed FWA-GPC performs better than the conventional AP optimization approaches.

• Journal of Astronomy and Space Sciences
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• v.18 no.2
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• pp.109-118
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• 2001

KITSAT-1, launched in 1992, passes through Inner Van Allen Radiation Belt in which high energy Protons cause single event upsets(SBUs) in the main memory of KITSAT-1 OBC(On-Board Computer) 186. The present paper compares SEU data from the OBC186 with the AP-8 model of NASA/NSSDC using the Chi-Square method to estimate the SEU threshold energy. Shielding effect by the satellite body has been taken into account to model the proton fluxes at the position of OBC186, and SEUs recorded during the high solar activities have been removed to avoid the spurious result. The result shows that the SEU threshold energy of the main memory of KITSAT-1 OBC186 is estimated to be about $110{pm}10MeV$.

• Journal of Electrical Engineering and Technology
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• v.8 no.1
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• pp.183-189
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• 2013

In this paper, we propose a capacity modeling method for Bluetooth based LBSs (Location Based Services) between Bluetooth APs(Access Points) and mobile phones. In order to do this, we consider the entrance and exit of the users to and from the AP. Using parameters such as the connection time, data transmission time and number of users in the AP zone, we analyze the capacity of a Bluetooth AP using an appropriate queuing model. The required number of APs in a certain zone is estimated from the number of users in the zone using the proposed queuing model. By performing simulations and experiments, the validity and applicability of the proposed method are verified.

• Nuclear Engineering and Technology
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• v.53 no.5
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• pp.1686-1704
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• 2021

This study addresses the numerical simulation of the shield building of an AP1000 nuclear power plant (NPP) subjected to a large commercial aircraft impact. First, a simplified finite element model (F.E. model) of the large commercial Boeing 737 MAX 8 aircraft is established. The F.E. model of the AP1000 shield building is constructed, which is a reasonably simplified reinforced concrete structure. The effectiveness of both F.E. models is verified by the classical Riera method and the impact test of a 1/7.5 scaled GE-J79 engine model. Then, based on the verified F.E. models, the entire impact process of the aircraft on the shield building is simulated by the missile-target interaction method (coupled method) and by the ANSYS/LS-DYNA software, which is at different initial impact velocities and impact heights. Finally, the laws and characteristics of the aircraft impact force, residual velocity, kinetic energy, concrete damage, axial reinforcement stress, and perforated size are analyzed in detail. The results show that all of them increase with the addition to the initial impact velocity. The first four are not very sensitive to the impact height. The engine impact mainly contributes to the peak impact force, and the peak impact force is six times higher than that in the first stage. With increasing initial impact velocity, the maximum aircraft impact force rises linearly. The range of the tension and pressure of the reinforcement axial stress changes with the impact height. The perforated size increases with increasing impact height. The radial perforation area is almost insensitive to the initial impact velocity and impact height. The research of this study can provide help for engineers in designing AP1000 shield buildings.

• Journal of Software Engineering Society
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• v.29 no.1
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• pp.13-21
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• 2020

As CNN model is applied to various domains such as image classification and object detection, the performance of CNN model which is used to safety critical system like autonomous vehicles should be reliable. To evaluate that CNN model can sustain the performance in various environments, we developed an image data augmentation apparatus which generates images that is changed background. If an image which contains object is entered into the apparatus, it extracts an object image from the entered image and generate s composed images by synthesizing the object image with collected background images. A s a method to evaluate a CNN model, the apparatus generate s new test images from original test images, and we evaluate the CNN model by the new test image. As a case study, we generated new test images from Pascal VOC2007 and evaluated a YOLOv3 model with the new images. As a result, it was detected that mAP of new test images is almost 0.11 lower than mAP of the original test images.

• Journal of Environmental Science International
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• v.24 no.3
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• pp.303-316
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• 2015

The relationship between urban spatial structures and GHG-AP integrated emissions was investigated by statistically analyzing those from 25 administrative districts of Seoul. Urban spatial structures, of which data were obtained from Seoul statistics yearbook, were classified into five categories of city development, residence, environment, traffic and economy. They were further classified into 10 components of local area, population, number of households, residential area, forest area, park area, registered vehicles, road area, number of businesses and total local taxes. GHG-AP integrated emissions were estimated based on IPCC(intergovernmental panel on climate change) 2006 guidelines, guideline for government greenhouse inventories, EPA AP-42(compilation of air pollutant emission factors) and preliminary studies. The result of statistical analysis indicated that GHG-AP integrated emissions were significantly correlated with urban spatial structures. The correlation analysis results showed that registered vehicles for GHG (r=0.803, p<0.01), forest area for AP (r=0.996, p<0.01), and park area for AP (r=0.889, p<0.01) were highly significant. From the factor analysis, three groups such as city and traffic categories, economy category and environment category were identified to be the governing factors controlling GHG-AP emissions. The multiple regression analysis also represented that the most influencing factors on GHG-AP emissions were categories of traffic and environment. 25 administrative districts of Seoul were clustered into six groups, of which each has similar characteristics of urban spatial structures and GHG-AP integrated emissions.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.4
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• pp.1396-1414
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• 2018

With the proliferation of the Internet of Things (IoT) healthcare devices, significant interoperability issue arises where devices use proprietary data transfer protocols. The IHE PCD-01 standard has been suggested for the exchange of healthcare data in ISO/IEEE 11073 PHD data model. However, the PCD-01 is not efficient to be used in the IoT environment. This is because the use of SOAP for PCD-01 may be too complex to be implemented in the resource-constrained IoT healthcare devices. In this paper, we have designed a communication system to implement ISO/IEEE 11073 and IHE PCD-01 integration using the IETF CoAP. More specifically, we have designed the architecture and procedures, using CoAP, to seamlessly transmit the bio-signal from the tiny resource-constrained IoT healthcare devices to the server in a standardized way. We have also built the agent, gateway, and PCD-01 interface at the server, all of which are using the CoAP as a communication protocol. In order to evaluate the performance of the proposed system, we have used the PCD data to be transmitted over CoAP, MQTT, and HTTP. The evaluation of the system performance shows that the use of CoAP results in faster transaction and lesser cost than other protocols, with less battery power consumption.

• Korean Journal of Computational Design and Engineering
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• v.9 no.2
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• pp.175-182
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• 2004

As a bridge between design and manufacturing, process planning is to generate a sequenced set of instructions to manufacture the specified part. Automatic interpretation of manufacturing information incorporated in the design documentation such as CAD file has been a knotty subject for manufacturing engineers since no current data exchange format for product data provides a perfect interface between heterogeneous systems. The recent neutral data exchange format STEp, standard for the exchange of product model data, includes not only geometry but also technical and managerial information. STEP AP(Application Protocol) 224 is specifically dedicated to the mechanical product definition for process planning using machining features. Given a design information in STEP AP 224 format, process planning can be made without human intervention. This paper describes a method to determine the sequence of machining features by using the machining features and the manufacturing information expressed in STEP AP224.