• 한국지진공학회논문집
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• 제12권2호
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• pp.69-80
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• 2008

본 연구에서는 중고층 건물과 같이 고차모드의 영향이 커지는 구조물의 지진에 대한 성능점을 간략하고 정확하게 구할 수 있는 개선된 능력스펙트럼법을 제안한다. 능력스펙트럼법은 주어진 지진의 응답스펙트럼과 다자유도 구조물을 변환한 등가 단자유도 시스템을 이용하여 지진으로 인하여 발생하는 지붕층의 최대 비탄성변위를 간략하게 구하는 방법이다. 제안된 방법에서는 구조물의 탄성 및 비탄성 동적해석을 수행하지 않고, 기존의 능력스펙트럼법에서 요구되는 정적푸쉬오버해석과 탄성변위를 이용하여 비탄성변위를 예측하는데, 기존 연구에서 개발한 $C_R$을 이용한다. 본 연구는 제안한 방법의 정확도를 평가하기 위해 LA 지역의 3, 9, 20층 철골모멘트저항골조를 선택한다. 이 건물들의 지진에 대한 각 층별 최대 층간변위비를 개발한 CSM으로 구하고, 이를 비선형 응답이력해석(NL-RHA)으로 구한 결과와 비교하였다. 사용한 지진은 재현주기 475년과 2475년의 위험수준에 대한 각각 20개의 지진집단들이다. 또한 본 연구에서는 ATC-40에 제시된 CSM 방법과 N2 방법으로 구한 각 건물의 최대 층간변위비도 비교한다. 개발된 CSM은 기존에 개발된 방법에 비하여 보다 정확한 최대 층간변위비를 예측하는 것으로 나타났다.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2016년도 추계학술대회
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• pp.107-109
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• 2016

본 논문에서는 4K UHD 입력 영상을 실시간으로 부호화하기 위해 적용되는 GOP 단위 또는 IDR 주기 단위의 병렬 부호화 구조를 지원하도록 R-${\lambda}$ 모델 기반의 율 제어 방법을 개선하는 비트 분배(bit allocation) 방법을 제안한다. GOP 단위 또는 IDR 주기 단위의 병렬 부호화기 내에서 율 제어기를 작동시키는 경우, 계층적 B 구조에서 같은 계층에 있는 프레임 간에는 상호간에 얼마만큼의 비트를 소모 하였는지에 대한 정보를 공유 할 수 없기 때문에 기존의 비트 분배 방식으로는 비트 예산(bit budget) 관리가 불가능하다. 이를 해결하기 위해 본 논문에서는, 기존의 R-${\lambda}$ 모델 기반 율 제어 방법을 개선하여 부호화 순서에 의한 시간 순서 방향의 비트 예산 갱신 기반 비트 분배하던 방식으로부터, GOP 마다 비트를 할당한 후 계층적 B 구조에서의 계층이 깊어지는 방향으로 비트 예산을 갱신하여 비트를 분배하는 방식으로 율 배분 방식을 개선하였다. 실험 결과를 통해 R-${\lambda}$ 모델 기반 율 제어의 기존 비트 분배 방식보다 제안 방법에 의한 목표 비트 율 달성 오차가 감소함을 확인하였다.

• Investigative Magnetic Resonance Imaging
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• 제20권4호
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• pp.231-240
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• 2016

Purpose: To determine whether liver stiffness (LS) measured by magnetic resonance elastography (MRE) can predict the outcome of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Materials and Methods: A total of 107 patients with Child-Pugh class A liver function who were treated with RFA for single HCC and who had undergone a gradient-echo MRE within 6 months before RFA were included. We evaluated the relationship between the LS values and the ablation volume, local tumor progression (LTP), and intrahepatic distant recurrence (IDR). We also constructed receiver operating characteristic (ROC) curves to examine the role of LS in predicting liver function deterioration, which was defined as an increase of Child-Pugh score by one point or more at 1 year after RFA. Results: There was no significant correlation between LS and ablation volume, and neither time to LTP nor IDR was associated with LS. Among the 66 patients who did not have recurrence 1 year after RFA, 5 patients (7.6%) developed liver function deterioration. A high LS value was significantly associated with development of liver function deterioration after RFA and the area under the ROC curve was 0.764 (95% CI 0.598-0.929, P = 0.003). Conclusion: LS measured by MRE could not predict ablation volume and tumor recurrence. However, high LS values were significantly associated with development of liver function deterioration.

• 한국항만경제학회지
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• 제19권2호
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• pp.111-139
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• 2003

In this paper, the unbiasedness hypothesis cannot be rejected for JPY. It means that Japanese forward exchange market is efficient. This implies that there would not be an unusual profit from speculation. However, the unbiasedness hypothesis can be rejected for THB, HKD, IDR. It means that Asian forward exchange market is inefficient. This implies that there would be an unusual profit from all available information. This suggests that forward exchange rates cannot be an unbiased estimator of future spot exchange rate. This result explains that the actual pricing for forward rate is not based on the international financial market's pricing mechanism of interest rate parity theory, but rather depends upon that simple market expectations and aspirations.

• International Journal of Knowledge Content Development & Technology
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• 제7권4호
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• pp.71-84
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• 2017

The paper discusses the nature of Knowledge Organization Systems (KOSs) and shows how these can support digital library users. It demonstrates processes related to integration of KOS like the Dewey Decimal Classification, $22^{nd}$ edition (DDC22) in DSpace software (http://www.dspace.org/) for organizing and retrieving (browsing and searching) scholarly objects. An attempt has been made to use the DDC22 available in Bengali language and highlights the required mechanisms for system-level integration. It may help a repository administrator to build an IDR (Institutional Digital Repository) integrated with SKOS-enabled multilingual subject access systems for supporting subject descriptors based indexing (DC.Subject metadata element), structured navigation (browsing) and efficient searching.

• Molecules and Cells
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• 제41권10호
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• pp.889-899
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• 2018

Intrinsically disordered proteins (IDPs) are highly unorthodox proteins that do not form three-dimensional structures under physiological conditions. The discovery of IDPs has destroyed the classical structure-function paradigm in protein science, 3-D structure = function, because IDPs even without well-folded 3-D structures are still capable of performing important biological functions and furthermore are associated with fatal diseases such as cancers, neurodegenerative diseases and viral pandemics. Pre-structured motifs (PreSMos) refer to transient local secondary structural elements present in the target-unbound state of IDPs. During the last two decades PreSMos have been steadily acknowledged as the critical determinants for target binding in dozens of IDPs. To date, the PreSMo concept provides the most convincing structural rationale explaining the IDP-target binding behavior at an atomic resolution. Here we present a brief developmental history of PreSMos and describe their common characteristics. We also provide a list of newly discovered PreSMos along with their functional relevance.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2007년도 정기 학술대회 논문집
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• pp.135-140
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• 2007

In this paper, an Improved Dimension Reduction(IDR) method is proposed for uncertainty quantification that employes Kriging interpolation technic. It has been acknowledged that the DR method is accurate and efficient for assessing statistical moments and reliability due to the sensitivity free feature. However, the DR method has a number of drawbacks such as instability and inaccuracy for problems with increased nonlineality. In this paper, improved DR is implanted by three steps. First, the Kriging interpolation method is used to accurately approximate the responses. Second, 2N+1 and 4N+1 ADOEs are proposed to maintain high accuracy of the method for UQ analysis. Third, numerical integration scheme is used with accurate but free response values at any set of integration points of the surrogated model.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2004년도 춘계종합학술대회
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• pp.420-423
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• 2004

컴퓨터 기술의 발달과 더불어 인터넷의 발전은 고속화되어 왔다. 이에 따라 데이터 전송 속도의 과속화와 대용량의 데이터 전송 둥의 기술이 증가되고 이로 인해 업무 효율을 향상됨에 따라 시스템 및 네트워크 차원에서 보안 기능에 대한 요구도 날로 증가하고 있다. 따라서 본 논문에서는 정보통신망 자체를 사이버 공격으로부터 보호하며, 정보통신망의 보안 취약점을 없애 해킹이나 정보유출을 원천적으로 차단할 수 있는 능동형 보안 관리 기술인 역추적 시스템을 분석하고 액티브 네트워크 기반의 역추적 시스템을 분석 및 설계하였다.

• Molecules and Cells
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• 제45권7호
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• pp.444-453
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• 2022

Multivalent macromolecular interactions underlie dynamic regulation of diverse biological processes in ever-changing cellular states. These interactions often involve binding of multiple proteins to a linear lattice including intrinsically disordered proteins and the chromosomal DNA with many repeating recognition motifs. Quantitative understanding of such multivalent interactions on a linear lattice is crucial for exploring their unique regulatory potentials in the cellular processes. In this review, the distinctive molecular features of the linear lattice system are first discussed with a particular focus on the overlapping nature of potential protein binding sites within a lattice. Then, we introduce two general quantitative frameworks, combinatorial and conditional probability models, dealing with the overlap problem and relating the binding parameters to the experimentally measurable properties of the linear lattice-protein interactions. To this end, we present two specific examples where the quantitative models have been applied and further extended to provide biological insights into specific cellular processes. In the first case, the conditional probability model was extended to highlight the significant impact of nonspecific binding of transcription factors to the chromosomal DNA on gene-specific transcriptional activities. The second case presents the recently developed combinatorial models to unravel the complex organization of target protein binding sites within an intrinsically disordered region (IDR) of a nucleoporin. In particular, these models have suggested a unique function of IDRs as a molecular switch coupling distinct cellular processes. The quantitative models reviewed here are envisioned to further advance for dissection and functional studies of more complex systems including phase-separated biomolecular condensates.

• Earthquakes and Structures
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• 제20권4호
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• pp.457-471
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• 2021

This study aims at providing a simple and effective methodology to define a meaningful characteristic period for special class of earthquake records named "pulse-like ground motions". In the proposed method, continuous wavelet transform is employed to extract the large pulse of ground motions. Then, Fourier amplitude spectra obtained from the original ground motion and the residual motion is simply compared. This comparison permits to define a threshold pulse-period (Tp∗) as the threshold period above which the pulse component has negligible contributions to the Fourier amplitude spectrum. The effect of pulse on frequency content of motions was discussed on the light of this definition. The advantage and superior features of the new definition were related to the inelastic displacement ratio (IDR) for single-degree-of-freedom systems with period equal to one half of the threshold period. Analyses performed for the proposed period at three ductility levels u=2,4,6 were compared with the results obtained at half of pulse period derived from wavelet analysis, peak-point method and the peak of product of the velocity and the displacement response spectra (Sv x Sd). According to the results, pulse effects on inelastic displacement ratio seem to be more important when $\frac{T_p^*}{T}=2$ (T is the fundamental vibration period of system). The results showed that utilizing of the proposed definition could facilitate an enhanced understanding of pulse-like records features.