• Fibers and Polymers
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• 제5권2호
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• pp.95-104
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• 2004

A series of superabsorbents based on acrylic acid (AA), sodium acrylate, 2-acrylamido-2-methylpropane sulphonic acid, N,N'-methylene bis-acrylamide (MBA) were prepared by inverse suspension polymerization. These hydrogels were further crosslinked on the surface with polyethylene glycol-600 (PEG-600). The water absorbency or swelling behaviors for these xerogels in water and 0.9% saline solutions, both under free condition and under load were investigated. Absorption characteristics of these hydrogels were found to depend on nature and concentration of crosslinker in the system. It was also found that the saline absorption was significantly improved as the incorporation of AMPS in the polymer was increased. The surface crosslinking introduced in the polymers was found to improve the absorption under load characteristics without lowering the free water absorption capacities of the polymer to a considerable extent.

• 대한전자공학회논문지
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• 제27권6호
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• pp.816-820
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• 1990

A Tx modulator of the AMPS cellular wireless communication has been implemented using the PLL synthesizer, of which is modified for multiple frequency output capability. The frequency range is in 825-845 MHz with the 666 channels of 30KHz channel spacing and its switching time is less than 40 msec. The purpose of this paper is to develope the PLL frequency synthesizer with the high speed pulse swallow prescaler in order to save power consumption and cost. The PLL frequency synthesizer is studied in this paper to apply the cellular communication modulator.

• JSTS:Journal of Semiconductor Technology and Science
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• 제1권3호
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• pp.167-181
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• 2001

A stepwise driving method was used for reducing the AC power consumption in a TFT-LCD. The AC power takes the largest portion of the total power consumption of a TFT-LCD. Experimental results confirmed that the AC power saving efficiency reached up to 75% when a 5-stepwise driving with each step time of $2\mu$ sec was applied to a 14.1 inch-diagonal XGA TFT-LCD. The second largest component of power consumption called the DC power comes from the quiescent currents in Op-amps. A simple and efficient architecture was proposed in this work to reduce this DC power consumption: Half of the Op-amps have the 5V-supplies, and the rest half have the 10V-supplies, and two Op-amps are shared by adjacent two channels. Measurements of test circuits showed that this simple method could reduce over 40% of the DC power consumption..

• Biomolecules & Therapeutics
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• 제21권4호
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• pp.251-257
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• 2013

Inflammatory skin diseases such as atopic dermatitis (AD) and rosacea were complicated by barrier abrogation and deficiency in innate immunity. The first defender of epidermal innate immune response is the antimicrobial peptides (AMPs) that exhibit a broad-spectrum antimicrobial activity against multiple pathogens, including Gram-positive and Gram-negative bacteria, viruses, and fungi. The deficiency of these AMPs in the skin of AD fails to protect our body against virulent pathogen infections. In contrast to AD where there is a suppression of AMPs, rosacea is characterized by overexpression of cathelicidin antimicrobial peptide (CAMP), the products of which result in chronic epidermal inflammation. In this regard, AMP generation that is controlled by a key ceramide metabolite S1P-dependent mechanism could be considered as alternate therapeutic approaches to treat these skin disorders, i.e., Increased S1P levels strongly stimulated the CAMP expression which elevated the antimicrobial activity against multiple pathogens resulting the improved AD patient skin.

• 정보보호학회논문지
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• 제10권2호
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• pp.55-66
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• 2000

이동컴퓨팅 환경은 기존의 컴퓨팅 환경과는 달리 호스트의 이동성과 무선 통신의 특성을 고려하여야 한다. 기존의 지불시스템들은 이와 같은 특성을 고려하지 않고 설계되었기 때문에 이동컴퓨팅 환경에서 이를 효율적으로 사용할 수 없다 본 논문에서는 이동컴퓨팅 환경에서 소액지불을 위한 새로운 전자지불시스템 AMPS(Atomic Micropayment System)를 제안한다. 이시스템은 고객인 이동 호스트의 연산 부담과 무선 통신 메시지의 수를 최소화하도록 설계되었다 AMPS 는 고객의 요청이 들어오면 대행 서버를 통해 고객을 대신하여 유선망에서 판매자를 상대로 상품거래를 대행하여 준다. AMPS는 소액의 디지털 상품 구매를 위한 지불시스템으로 지불 트랜잭션의 원자성(atomicity)을 보장한다. 또한 판매자와 제 3자로부터 고객의 익명성과 대행 서버가 구매 상품 내역에 대해 알수 없도록 구매 상품의 비밀을 보장한다. AMPS 프로토콜의 안정성과 효율성에 대해서도 분석하였다.

• 생명과학회지
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• 제25권6호
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• pp.715-723
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• 2015

지구상에 존재하는 전체 동물 중 가장 큰 부분을 차지 하고 있는 곤충은 예로부터 인간의 식품, 농업, 산업, 의약 등의 일상 생활에 이용되어 왔다. 많은 수와 높은 영양학적 가치로 곤충의 생리활성물질이 미개발 생물자원으로 재평가 되고 있다. 곤충은 면역세포, 곤충 혈구세포, 효소들의 연쇄반응 혹은 항균 단백질/펩타이드 같은 방법으로 외부의 감염에 저항성을 가지게 된다. 항균 펩타이드는 곤충의 혈림프의 선천성 면역 시스템 중 주요한 성분중의 하나로 항생제 내성 균주의 출몰이 빈번하게 일어나 해결책으로 새로운 항생제 개발이 시급한 시점에서 유력한 후보물질로 주목 받고 있다. 곤충 유래 항균 펩타이드는 150개가 넘게 분리되었으며 크게 세크로핀, 디펜신, 글라이신/프롤린이 풍부한 펩타이드로 이루어진다. 이 논문에서, 향균 펩타이드를 생산하는 여러 곤충 중에서 벌, 소똥구리, 울도하늘소, 나비 그리고 울도하늘소에서 얻을 수 있는 펩타이드의 종류 그리고 작용 기작에 대해 알아보았다. 이 펩타이드들은 항균효과를 가지고 있으며 멜리틴을 제외하고 적혈구의 용혈 현상이 나타나지 않고 주로 세포막을 붕괴시키거나 세포자살기작을 유도하여 병원성 미생물의 성장을 억제한다. 곤충 유래 펩타이드와 같은 생리활성물질이 그 활용 가능성의 면에서 엄청난 가능성을 가지고 있어 이에 대한 연구는 앞으로 더 주목을 받을 것이다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 하계종합학술대회논문집
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• pp.859-862
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• 1998

An offset compensation scheme for rail-to-rail CMOS op-amps with complementary input stages is presented. Two auxiliary amplifiers are used to compensate for the offsets of NMOS and PMOS differnetial input stages, and ping-pong control is employed for continuous-time operation. Simulation and measurements resutls show that offsets are reduced about 20 times by this scheme.

• 한국산학기술학회논문지
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• 제16권3호
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• pp.1894-1903
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• 2015

본 연구의 목적은 만성뇌졸중 환자에게 운동학습이론을 기초한 물리치료와 작업치료를 병행한 집단 과제지향적 순환훈련 프로그램을 실시하여 운동기능, 일상생활동작과 삶의 질적인 변화를 알아보고자 하였다. 6명의 만성 뇌졸중 환자에게 31주간 실시하였다. Chedoke-McMaster 뇌졸중평가, 균형검사, 일상생활활동 운동 처리기술 평가(Assessment of Motor and Process Skills: AMPS)와 뇌졸중 영향척도 측정을 치료 전과 후에 수집하였다. 연구결과, 운동기능 손상영역, 균형과 뇌졸중 영향척도의 기분과 정서영역에서 통계적으로 유의하게 향상되었다. 일상생활활동 운동 처리기술 평가는 운동(motor)영역에서 6명 중 3명에게 처리(process)영역은 4명에서 훈련 후 향상되었다. 본 연구결과를 바탕으로 집단 과제지향적 순환훈련은 지역사회 만성 뇌졸중 환자의 신체적 기능 향상에 이점이 있다고 제언하는 바이다.

• Journal of Microbiology and Biotechnology
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• 제26권11호
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• pp.1863-1870
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• 2016

Antimicrobial peptides/proteins (AMPs) are present in all types of organisms, from microbes and plants to vertebrates and invertebrates such as insects. The grasshopper Oxya chinensis sinuosa is an insect species that is widely consumed around the world for its broad medicinal value. However, the lack of available genetic information for this species is an obstacle to understanding the full potential of its AMPs. Analysis of the O. chinensis sinuosa transcriptome and expression profile is essential for extending the available genetic information resources. In this study, we determined the whole-body transcriptome of O. chinensis sinuosa and analyzed the potential AMPs induced by bacterial immunization. A high-throughput RNA-Seq approach generated 94,348 contigs and 66,555 unigenes. Of these unigenes, 36,032 (54.14%) matched known proteins in the NCBI database in a BLAST search. Functional analysis demonstrated that 38,219 unigenes were clustered into 5,499 gene ontology terms. In addition, 26 cDNAs encoding novel AMPs were identified by an in silico approach using public databases. Our transcriptome dataset and AMP profile greatly improve our understanding of O. chinensis sinuosa genetics and provide a huge number of gene sequences for further study, including genes of known importance and genes of unknown function.

• 한국미생물·생명공학회지
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• 제38권1호
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• pp.19-23
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• 2010

Recently, marine organisms are emerging as a leading group for identifying and extracting novel bioactive substances. These substances are known to possess a potential regarding not only as a source of pharmaceutical products but also their beneficial effects on humans. Among the substances, antimicrobial peptides (AMPs) specifically have attracted considerable interest for possible use in the development of new antibiotics. AMPs are characterized by relatively short cationic peptides containing the ability to adopt a structure in which cationic or hydrophobic amino acids are spatially scattered. Although a few reports address novel marine organisms-derived AMPs, their antimicrobial mechanism(s) are still remain unknown. In this review, we summarized the peptides previously investigated, such as Pleurocidin, Urechistachykinins, Piscidins and Arenicin-1. These peptides exhibited significant antimicrobial activities against human microbial pathogens without remarkable hemolytic effects against human erythrocytes, and their mode of actions are based on permeabilization of the plasma membrane of the pathogen. Therefore, the study of antimicrobial peptides derived from marine organisms may prove to be useful in the design of future therapeutic antimicrobial drugs.