• 한국정보디스플레이학회:학술대회논문집
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• 2003.07a
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• pp.686-689
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• 2003

This paper describes two kind of new concept for low power consumption for small area TFT-LCDs. First, the proposed analog buffer could reduce the static current by adopting new scheme. Second, new data driver structure reduced DC power consumption by reducing the number of operational amplifier (op-amp). As simulation results of Hspice, the quiescent current of proposed analog buffer is less than $0.8{\mu}A$ and the DC power consumption is reduced about $40{\sim}50%$ compared with conventional ones.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.3
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• pp.13-18
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• 2010

This work proposes and characterizes switched-capacitor type cyclic digital-to-analog converter for display data driving. The proposed digital-to-analog converter composes simple structure, and can be implemented for low-power, small area display driver ICs. By circuit level simulations, it is verified that the op-amp input referred offset is attenuated at the DAC output and the circuit performance is robust at 0.5% of capacitor mismatch.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.437-438
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• 2008

This paper proposes a 8th-order single loop band-pass sigma-delta modulator that satisfies a wide bandwidth of 6MHz, which is required for a HDTV application. The proposed architecture is based on a simple analog structure that enlarges the noise shaping with a low OSR. In addition, a feedforward scheme is used to relax op-amp performance requirements. The proposed modulator has been simulated using the 0.18um 1.8v TSMC technology. The simulation results show that the bandwidth is 6MHz and SNQR is 70dB.

• Journal of the Korean Society for Nondestructive Testing
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• v.33 no.2
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• pp.232-240
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• 2013

This paper presents recent advances in damage visualization algorithms of laser generated ultrasonic propagation imaging(UPI) system. An effective damage evaluation method is required to extract correct information from raw data to properly characterize anomalies present in structure. A temporal-reference free imaging system provides easy and rapid defect inspection capability with less computational complexity. In this paper a number of methods such as ultrasonic wave propagation imaging(UWPI), anomalous wave propagation imaging(AWPI), ultrasonic spectral imaging(USI), wavelet ultrasonic propagation imaging(WUPI), variable time window amplitude mapping(VTWAM), time point adjustment(TPA), time of flight and amplitude mapping(ToF&Amp) and ultrasonic wavenumber imaging(UWI) are discussed with instances of successful implementation on various structures.

• Bulletin of the Korean Chemical Society
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• v.34 no.2
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• pp.565-568
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• 2013

Acetyl-CoA carboxylases (ACCs) play critical roles in fatty acid synthesis and oxidation by the catalytic activity of the carboxylation of acetyl-CoA to malonyl-CoA. It is known that ACCs are inactivated through reversible phosphorylation by AMP-activated protein kinase (AMPK) and allosterically activated by citrate. Here, we determined the crystal structures of biotin carboxylase (BC) domain of human ACC2 phosphorylated by AMPK in the presence of citrate in order to elucidate the activation mechanism by citrate. This structure shows that phosphorylated Ser222 is released from the dimer interface, and thereby facilitating the dimerization or oligomerization of the BC domain allosterically. This structural explanation is coincident with the experimental result that the phosphorylated Ser222 was dephosphorylated more easily by protein phosphatase 2A (PP2A) as the citrate concentration increases.

• Journal of the Semiconductor & Display Technology
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• v.17 no.3
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• pp.104-107
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• 2018

In this paper, we developed a sensor for monitoring the leakage current through the chassis of the robot. The leakage current sensor needs to be developed because it is a necessary part to prevent electric shock accidents that may occur through the chassis of a robot or an electric vehicle. This leakage monitoring sensor was developed to be mounted directly on the chassis of the robot. This sensor protects the control system from noise by discharging static and high-frequency noise that may occur in the chassis of the robot and monitors the leakage current by measuring the amount of current discharged through the ground. In this paper, a leakage monitoring sensor was developed with a simple structure using resistors, capacitors and OP-AMP, and the performance was evaluated.

• The Transactions of the Korean Institute of Power Electronics
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• v.26 no.1
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• pp.66-73
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• 2021

This study presents a novel four-channel light-emitting diode (LED) current balancing topology using a current-fed hybrid quasi-Z-source converter. With the proposed structure, currents flowing through four LED strings are automatically balanced owing to the charge (amp-sec) balance condition on capacitors. Thus, automatic current balancing of the proposed driver is simple and precise. In addition, the proposed LED driver uses only one active switch and three diodes. The operating principle and characteristics of the proposed four-channel LED driver are analyzed in detail. To verify the operation of the proposed LED driver, a prototype is built and tested with different numbers of LEDs.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.189.1-189.1
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• 2003

4-(4-Methoxyphenyl)-2-aminothiazole and 3-(4-methoxyphenyl)-5-aminothiadiazole derivatives have been synthesized and evaluated as selective antagonists for human adenosine A$_3$ receptors. A methoxy group in the 4-position of the phenyl ring and N-acetyl or propionyl substitutions of the aminothiazole and aminothiadiazole templates displayed great increases of binding affinity and selectivity for human adenosine A$_3$ receptors. The most potent A$_3$ antagonist of the present series, N-［3-(4-methoxy-phenyl)-［1,2,4］thiadiazol-5-yl］-acetamide exhibiting a K$\_$i/ value of 0.79 nM at human adenosine A$_3$ receptors, showed antagonistic property in functional assay of cAMP biosynthesis involved in one of the signal transduction pathways of adenosine A$_3$ receptors. (omitted)

• Proceedings of the Korean Society of Applied Pharmacology
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• 1997.04a
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• pp.86-86
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• 1997

Human annexin I is a member of annexin family of calcium dependent phospholipid binding proteins, which have been implicated in various physiological roles including phospholipase A$_2$ (PLA$_2$) inhibition, membrane fusion and calcium channel activity. In this work, the structure of N-terminally truncated human annexin I (Δ-annexin I) and its interactions with Ca$\^$2+/, ATP and cAMP were studied at atomic level by using $^1$H, $\^$15/N, $\^$l3/C NMR (nuclear magnetic resonance) spectroscopy. The effect of Ca$\^$2+/ binding on the structure of Δ-annexin I was investigated, and compared with that of Mg$\^$2+/ binding. The addition of Ca$\^$2+/ to Δ-annexin I caused some changes in the high field and low field regions of $^1$H NMR spectra. Whereas, upon addition of Mg$\^$2+/ to Δ-annexin I, almost no change could be observed. Also we found that the binding ratio of ATP to Δ-annexin I is 1. Because Δ-annexin I is a large protein with 35 kDa molecular weight, site-specific (carbonyl-$\^$l3/C, amide-$\^$15/N) labeling technique was used to determine the interaction sites of Δ-annexin I with Ca$\^$2+/ and ATP. Assignments of all the histidinyl carbonyl carbon resonances have been completed by using Δ-annexin I along with its specific 1,2-subdomain. The carbonyl carbon resonances originating from His52 and His246 of Δ-annexin I were significantly affected by Ca$\^$2+/ binding, and some Tyr and Phe resonances were also affected. The carbonyl carbon resonances originating from His52 is significantly affected by ATP binding, therefore His52 seems to be involved in the ATP binding site of Δ-annexin I.

• Animal cells and systems
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• v.11 no.2
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• pp.199-204
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• 2007

HCN (hyperpolarization-activated cyclic nucleotide-gated) channels, whose gene family consists of four subunits (HCN1-4), mediate depolarizing cation currents and contribute to controlling neuronal excitability. In the present study, immunohistochemical and electrophysiological approaches were used to elucidate the role of HCN channels in the cerebellum. Immunohistochemical labeling for HCN1 and HCN2 channels revealed localized expression of both channels at pinceau, the specialized structure of presynaptic axon terminals of basket cells. To determine the functional role of the presynaptic HCN channels, spontaneous inhibitory postsynaptic currents (IPSCs) were recorded from Purkinje cells, the main synaptic targets of basket cells in the cerebellum. While activation of HCN channels by 8-bromo-cAMP increased amplitude of spontaneous IPSCs, blockade of the activated HCN channels by subsequent ZD7288 application reduced the amplitude of spontaneous IPSCs to the level far below the control. Our results imply that modulation of HCN1 and HCN2 channels in presynaptic terminals of basket cells regulates neurotransmitter release, thereby controlling the excitability of Purkinje cells.