• 제목/요약/키워드: AMP

검색결과 1,915건 처리시간 0.028초

압전형 가속도 센서의 잡음 대책

  • 곽증효;최동수;김점호;손은영
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 1991년도 추계학술대회 논문집
    • /
    • pp.90-93
    • /
    • 1991
  • 압전형 가속도 센서(AMP 내장형 PA-01)의 전원 NOISE 영향은 가속도 센서의 금속부 구조 및 내장된 임피이던스 변환기의 역할을 하는 내장 AMP의 차페성 저항등에 원인에 있었다. 이 전원 NOISE 영향을 저하시키기 위하여 가속도 센서부의 UNIT CELL과 HOUSING 본체와의 절연 저항을 600㏁ 이상 되게하여 절연성 향상 및 임피이던스 변환기의 차페로 인하여 전원 NOISE 영향을 1/200∼1/2000 정도로 감소시킬수 있었다. 이때 UNIT CELL과 HOUSING 본체와의 절연 처리오 NOISE차페효과로 1/20 정도로 줄일 수 있었으며, 내장 AMP 차페로는 1/10∼1/100의 노이즈 차페효과를 얻을 수 있었다.

Bending of DNA by cAMP Receptor Protein(CRP)

  • 정수열
    • 생명과학회지
    • /
    • 제4권3호
    • /
    • pp.119-123
    • /
    • 1994
  • CRP에 의한 DNA bending의 첫 실험은 cAMP, CRP, DNA complex의 gelelectrophoresis에 의해 확인되었다. Bent DNA fragment의 이동은 같은 크기의 linear fragment보다 느리며, EH cAMP, CRP, DNA 결합위치에 따라서 상이한 이동 pattern을 나타낸다. 즉, DNA 단편의 중앙에 CRP binding site가 있을 때는 말단부분에 있을 때보다 이동도가 느리다. benting각의 크기는 일반적으로 안정한 복합체의 형성에 관계하며, 큰 각을 갖는 것이 보다 더 안정된 구조를 형성하여 전사가 촉진되는 것으로 밝혀져 있다. 본고에서는 CRP에 의한 bending과 CRP에 의한 전사조절 관계와 bending의 관계에 대하여 알아보았다.

  • PDF

Involvement of Phosphodiesterase Isozymes in Osteoclast Formation

  • Yim, Mi-Jung
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
    • /
    • pp.207.2-207.2
    • /
    • 2003
  • cAMP acts as a second messenger in the functional responses of various cells to hormones, cytokines and other agents. In turn, this nucleotide also modulates the signal transduction processes regulated by a range of cytokines and growth factors. The intracellular level of cAMP is regulated by a G protein coupled adenylyl cyclase and degradation is mediated by the phosphodiesterases (PDEs), a superfamily of enzymes that catalyze the hydrolysis of cAMP. (omitted)

  • PDF

EFFECTS OF HYPOPHYSECTOMY ON PROGESTERONE PRODUCTION IN THE FOLLICULAR GRANULOSA CELLS OF THE JAPANESE QUAIL

  • Mori, M.;Kimora, K.;Yamamuro, H.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제1권3호
    • /
    • pp.143-147
    • /
    • 1988
  • In order to investigate the mechanism of regulation of progesterone production, quail were hypophysectomized at various times during the ovulation cycle, and granulose cells were isolated from follicles 4 hr after the operation. They were incubated in vitro at $40^{\circ}C$ with or without LH or dibutyryl cyclic AMP, and the amounts of progesterone produced during 3 hr of incubation were measured by radioimmunoassay. Hypophysectomy at 8 hr or 20 hr before the predicted time of ovulation caused a reduced responsiveness of F1 granulosa cells to exogenous LH or dibutyrul cyclic AMP. Although hypophysectomy at 24 hr before ovulation caused a slight reduction of responsiveness of F1 granulosa cells, the reduction of the progesterone production during the incubation without any stimuli was prominent by the sham operation. These results suggest that the presence of pituitary gland influences the ability of the granulose cells to produce progesterone in response to LH or dibutyryl cyclic AMP.

Chemical Genetics Approach Reveals Importance of cAMP and MAP Kinase Signaling to Lipid and Carotenoid Biosynthesis in Microalgae

  • Choi, Yoon-E;Rhee, Jin-Kyu;Kim, Hyun-Soo;Ahn, Joon-Woo;Hwang, Hyemin;Yang, Ji-Won
    • Journal of Microbiology and Biotechnology
    • /
    • 제25권5호
    • /
    • pp.637-647
    • /
    • 2015
  • In this study, we attempted to understand signaling pathways behind lipid biosynthesis by employing a chemical genetics approach based on small molecule inhibitors. Specific signaling inhibitors of MAP kinase or modulators of cAMP signaling were selected to evaluate the functional roles of each of the key signaling pathways in three different microalgal species: Chlamydomonas reinhardtii, Chlorella vulgaris, and Haematococcus pluvialis. Our results clearly indicate that cAMP signaling pathways are indeed positively associated with microalgal lipid biosynthesis. In contrast, MAP kinase pathways in three microalgal species are all negatively implicated in both lipid and carotenoid biosynthesis.

다중도선 코로나 선전리형 TEA $CO_2$ 레이저 증폭기의 증폭특성 (Amplification Characteristics of Multiple-Wire Corona Preionization type TEA $CO_2$ Laser)

  • 임창문
    • 한국광학회:학술대회논문집
    • /
    • 한국광학회 1990년도 제5회 파동 및 레이저 학술발표회 5th Conference on Waves and lasers 논문집 - 한국광학회
    • /
    • pp.59-63
    • /
    • 1990
  • Two-stage TEA(transversely excited atmospheric pressure) CO2 laser amplifier system, Amp I and Amp II are consturcted and their amplification characteristics are investigated theoretically and experimentally. Multiple-wire corona preionization method is used for uniform discharge in laser oscillator and amplifiers. At optimumm gas ratio, CO2 : N2 : He = 1 : 1 : 3, output pulse energy of the oscillator is 0.4J and finally two-stage amplification gives 1.5J output energy which is larger than pumping threshold of para-H2 Raman laser. The rate equations of the amplifiers are solved numerically, and the results are compared with the experimental results. In conclusion, the small signal gain cocfficient of AMP I is 0.025/cm and that of AMP II is 0.02/cm.

  • PDF

Regulation of NO from Endothelial Cells by the Decrease of Cellular cAMP Under Arsenite Exposure

  • Lee, Soo-Youn;Min, Ji-Ho
    • Journal of Microbiology and Biotechnology
    • /
    • 제18권2호
    • /
    • pp.392-395
    • /
    • 2008
  • In an attempt to delineate the direct effect of arsenite-induced endothelial dysfunction on nitric oxide (NO) production, confluent bovine aortic endothelial cells (BAEC) were incubated with arsenite, and endothelial NO synthase expression and NO production were measured. Exposure of arsenite decreased NO production for up to 24h. This decrease was accompanied by decreases in cAMP, protein kinase A (PKA) activity, and furthermore, significant reduction of pCREB. In conclusion, this study is the first to demonstrate that exposure of arsenite decreases NO production by a reduction of pCREB and PKA activity that may be mediated by cAMP, leading to endothelial dysfunction.

가토(家兎)의 신장기능(腎臟機能)에 미치는 측뇌실내(側腦室內) cAMP의 영향(影響) (Influence of Intraventricular cAMP on the Renal Function of the Rabbit)

  • 국영종;최봉규
    • 대한약리학회지
    • /
    • 제13권2호
    • /
    • pp.35-39
    • /
    • 1977
  • Cyclic adenosine monophosphate (cAMP), known as a versatile regulator of cellular processes and as a secondary messenger of various hormones and other biogenic agents, such as prostaglandins and histamine, induced prompt and transient antidiuresis followed by mild natriuresis and diuresis, when it was administered into the lateral ventricle of the rabbit in doses ranging from $100\;{\mu}g$ to 1 mg. The initial antidiuresis was brought about by the systemic hypotension, whereas the secondary diuresis seemed to be resulted from the decreased tubular reabsorption of sodium, suggestive of participation of certain endogenous natriuretic agent. This observation suggests that cAMP might be involved in the center-mediated renal action of prostaglandins.

  • PDF

전력소모가 적합화된 고전력 연산증폭기의 설계 및 제작 (The Design of Power Operational Amplifier with optimized Power Dissipation)

  • 정해용;최인규;박종식
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2001년도 합동 추계학술대회 논문집 정보 및 제어부문
    • /
    • pp.38-41
    • /
    • 2001
  • To reduce the wasted power with using an OP-AMP, 3 circuit supplying the same amount of power to load through overall voltage range can able proposed. With this type of design, the power that induced to the devices in the circuit will be reduced, we can also develope a small size power supply with the OP-AMP developed using this design. If we need a OP-AMP needed to handle higher power than usual, another design technique can be proposed. With substituting one device with the devices connected in series, the power loaded to each devices in the series devices can be reduced. This thesis contents the design of an OP-AMP to use in high power fields with small thermal dissipation.

  • PDF

CRP의 전사 조절계 (Transcriptional Regulatory System by CRP)

  • 최용락
    • 생명과학회지
    • /
    • 제2권1호
    • /
    • pp.2-10
    • /
    • 1992
  • cAMP-CRP complex에 의해 전사조절을 받는 관련유전자의 구조, 특징, 조절양상, 기작과 CRP의 생화학적 및 분자생물학적이해 등을 살폈다. 그러나 대장균의 전체유전자의 구조해석이 연구사업으로 실행되어지고 있는 현실에서 볼 때 CRP의 조절하에 있는 유전자군이 보다 더 복잡 다양한 system으로 생각되어져서 CRP조절계의 전체적인 양상으로 해명하기 위한 연구도 이루어질 것으로 생각되어진다. 즉, cAMP-CRP의 조절하에 있는 조절영역의 전체를 파악함은 operon의 발현조절의 해명에 중요한 기틀이 될 뿐만 아니라 개별유전자의 이해를 위한 것보다 복잡한 세포 전체의 제어계를 분자적수준에서 해결하는데 중요한 과제라고 사료되어진다. 몇 가지 연구 결과에서는 cAMP-CRP가 결합은 하면서도 발현조절에는 관여하지 않는다든지, cAMP가 결합하지 않으면서도 전사조절을 받을 수 있는 유전자들이 밝혀지고 있다.

  • PDF