• 제목/요약/키워드: AL072

검색결과 22건 처리시간 0.024초

Effect of AL072, a Novel Anti-Legionella Antibiotic, on Growth and Cell Morphology of Legionella pneumophila

  • Kang, Byeong-Cheol;Park, Jae-Hak;Lee, Yong-Soon;Suh, Jung-Woo;Chang, Jun-Hwan;Lee, Chul-Hoon
    • Journal of Microbiology and Biotechnology
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    • 제9권3호
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    • pp.371-375
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    • 1999
  • AL072 is a potent anti-Legionella antibiotic produced by Streptomyces strain AL91. The minimum inhibitory concentration (MIC) of AL072 against Legionella pneumophila was 0.2$\mu$g/ml. Bacterial growth was rapidly inhibited at the dose range between the MIC and 20 times of the MIC when the antibiotic was added at the mid-exponential phase. Ultrastructural changes in L. pneumophila were observed upon treatment with AL072. Under electron microscopical observation, the organisms treated with AL072 exhibited characteristic morphological changes in the cellular outer coat. Also irregular morphological changes, such as the formation of filamentous materials in the cytoplasm, an increase in the size and number of cytoplasmic vacuoles, the extruding of cytoplasmic contents, the formation of spheroplast and ghost cells, and blebbings in the cell wall were observed. Furthermore, immunoelectron microscopical observation of the group treated with the MIC showed that the immune complex attached mainly to the cell wall. The results of these experiments indicate that AL072, like the inhibitors of cell wall synthesis, act selectively on the cell wall of L. pneumophila.

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실험계획법에 의한 Al/SiC 복합재료의 최적공정 설계 (Optimal Parameter Design for Al/SiC Composites using Design of Experiments)

  • 이광진;김균택;김영식
    • 동력기계공학회지
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    • 제15권5호
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    • pp.72-76
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    • 2011
  • In this work, the parameter optimization for thermal-sprayed Al/SiC composites have been designed by $L_9(3^4)$ orthogonal array and analysis of variance(ANOVA). Al/SiC composites were fabricated by flame spray process on steel substrate. The hardness of composites were measured using micro-vickers hardness tester, and these results were analyzed by ANOVA. The ANOVA results showed that the oxygen gas flow, powder feed rate and spray distance affect on the hardness of the Al/SiC composites. From the ANOVA results, the optimal combination of the flame spray parameters could be extracted. It was considered that experimental design using orthogonal array and ANOVA was efficient to determine optimal parameter of thermal-sprayed Al/SiC composites.

Al2O3 + (Fe2O3, Al, Cr and Si) 소결 복합재료의 고온 부식 특성 (High-temperature corrosion properties of Al2O3 + (Fe2O3, Al, Cr and Si) mixed sintering materials)

  • 김민정;원성빈;봉성준;이동복;손인진
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2012년도 춘계학술발표회 논문집
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    • pp.170-171
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    • 2012
  • $Fe_2O_3$, Al, Cr과 Si 분말을 고 에너지 볼 밀링해서 나노분말을 제조한 후 고주파유도 가열 활성 연소합성 장치로 1분 이내의 짧은 시간에 합성 및 소결한 $Al_2O_3+4.65(Fe_{0.43}Cr_{0.17}Al_{0.323}Si_{0.077})$, $Al_2O_3$ + 5.33 ($Fe_{0.375}Cr_{0.11}Al_{0.3}Si_{0.075}$), $Al_2O_3$ + 6.15 ($Fe_{0.325}Cr_{0.155}Al_{0.448}Si_{0.072}$), $Al_2O_3$ + 3.3 ($Fe_{0.6}Cr_{0.3}Al_{0.6}$) 소결체 시편을 $700^{\circ}C$의 온도에서 100시간 동안 공기 중에서 산화 및 $N_2-H_20-H_2S$ 혼합 가스 내에서 황화 부식을 실시하였다. 그 결과 산화 및 황화 부식 후에 ${\alpha}-Al_2O_3$가 표면에 생성되어 보호 피막으로 작용하여 우수한 내식성을 보였다.

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Nd:YAG 레이저를 이용한 알루미늄도금강판의 용접성(II) - 용접부내 알루미늄의 거동 - (Welding Characteristics of Aluminized Steel Sheet by Nd:YAG Laser(II) - Behavior of Al element in the weld -)

  • 김종도;이정한;김기철
    • Journal of Welding and Joining
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    • 제25권4호
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    • pp.72-78
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    • 2007
  • Aluminized steel sheet is a material with excellent heat resistance, thermal reflection and corrosion resistance. It has wide applications, owing to its low cost and excellent performance, in the petrochemical industry, electric power and other energy conversion systems, etc and has attracted the attention of many investigators. But the welding of aluminized steel sheet has a problem of decreasing tensile-shear strength, caused by mixed Al in the weld. This study investigated behavior of Al and its structural properties to resolve this problem. Several analysis equipment(SEM, EDX, EPMA) were used to investigate Al element in the weld. Also microhardness tester and TEM equipment were used to find the intermetallic compound. As a result of this study, Al-rich zones existed in the weld and Fe-Al intermetallic compounds were found in these zones. At the same time, the weldability of aluminized stainless steel sheet was investigated and compared with that of aluminized steel sheet. Although there is a difference between the base metal of the low carbon steel and stainless steel, it is interpreted that a behavior of Al element in the weld is similar.

오디오 딥러닝을 활용한 Al, Steel 소재의 절삭 깊이에 따른 오디오 판별 (A Study on Acoustic Signal Characterization for Al and Steel Machining by Audio Deep Learning)

  • 김태원;이영민;최해운
    • 한국기계가공학회지
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    • 제20권7호
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    • pp.72-79
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    • 2021
  • This study reports on the experiment of using deep learning algorithms to determine the machining process of aluminium and steel. A face cutting milling tool was used for machining and the cutting speed was set between 3 and 4 mm/s. Both materials were machined with a depth to 0.5mm and 1.0mm. To demonstrate the developed deep learning algorithm, simulation experiments were performed using the VGGish algorithm in MATLAB toobox. Downcutting was used to cut aluminum and steel as a machining process for high quality and precise learning. As a result of learning algorithms using audio data, 61%-99% accuracy was obtained in four categories: Al 0.5mm, Al 1.0mm, Steel 0.5mm and Steel 1.0mm. Audio discrimination using deep learning is derived as a probabilistic result.

Strain-free AlGaN/GaN 자외선 센서용 나노선 소자 연구 (Strain-free AlGaN/GaN Nanowires for UV Sensor Applications)

  • 안재희;김지현
    • Korean Chemical Engineering Research
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    • 제50권1호
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    • pp.72-75
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    • 2012
  • Strain-free AlGaN/GaN 나노선을 기판에 분산시킨 후 E-beam lithography(EBL)를 이용해 단일 나노선 자외선 센서를 제작하였다. 나노선의 구조적, 광학적 특성을 분석하기 위해 focused ion beam(FIB), photoluminescence, micro-Raman spectroscopy를 이용하여 나노선의 strain 및 형태를 조사하였다. 자외선 센서로서의 특성 여부를 확인하기 위하여 빛을 차단 한 조건과 자외선을 조사하는 조건하에서 current-voltage(I-V) 특성을 측정하였으며 각각 9.0 ${\mu}S$과 9.5 ${\mu}S$의 전기전도도(conductance)를 얻었다. 자외선 조사 조건하에서 excess carrier의 증가로 인해 전기전도도가 약 5%가 향상되었음을 알 수 있었다. 자외선을 반복적으로 조사하는 과정의 실험을 통해 우수한 포화 시간(saturation time)과 감쇠 시간(decay time)을 얻었다. 따라서 AlGaN/GaN 나노선은 자외선 센서로서 많은 가능성을 가지고 있음을 확인하였다.

$LaAlO_3-BaZrO_3$계 perovskites의 제조 및 유전특성 (Fabrication and dielectric properties of $LaAlO_3-BaZrO_3$ perovskites)

  • 이소희;김신;신현호
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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    • pp.325-325
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    • 2007
  • The perovskites in the $LaAlO_3-BaZrO_3$ system (i.e., $(1-x)LaAlO_3-xBaZrO_3$ were fabricated by a solid state reaction and their dielectric properties were investigated. For the compositions of x=0.1~0.9, the mixture of $LaAlO_3$ with a rhombohedral structure and $BaZrO_3$ with a cubic was observed when the sintering was conducted at $1500^{\circ}C$, indicating that the solubility of constituent elements was very low and a narrow solid solution region might exist. The large difference of ionic radii between $La^{3+}$ ion (0.136nm, C.N.=12) and $Ba^{2+}$ ion (0.161nm) or $Al^{3+}$ ion (0.0535nm, C.N.=6) and $Zr^{4+}$ ion (0.072nm) might hinder the mutual substitution. Within the compositions of x=0~0.7, the dielectric constant of the mixture increased with the amount of $BaZrO_3$, i.e., x value, which was in good agreement with the logarithmic mixing rule (In $_{r,i}={\Sigma}v_iln\;_{r,i}$). The increase in $BaZrO_3$ doping decreased $Q{\times}f$ value significantly due to the low $Q{\times}f$ value of $BaZrO_3$ itself, a poor microstructure of the mixture with an increased grain boundary area per volume, and defects in the cation and oxygen sub-lattices which were respectively caused by the evaporation of barium during the sintering process and the substitution of Ba on La-site or Al on Zr-site.

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무노즐 부스터 성능해석 (Performance Analysis of the Nozzleless Booster)

  • 김경무;길태옥;류태하
    • 한국추진공학회지
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    • 제21권2호
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    • pp.72-82
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    • 2017
  • 무노즐 부스터는 통합형 로켓 램제트 추진기관에 적용되는 구성품 중 하나이다. 무노즐 고체 부스터의 성능을 예측하기 위해서 간단한 이론적 해석이 L/D=5, 6, 7, 9, 11, 그리고 13에 적용되었다. 연소가스 유동 효과 때문에 경도를 증가시키기 위해서 금속함량이 높은 Al-HTPB 및 Zr-HTPB 추진제가 사용되었다. 간단한 이론 해석과 시험결과 사이의 경향은 유사하게 나타났다.

복사열전달이 고체 추진제의 동적소화에 미치는 영향 (The Effect of Radiative Heat Flux on Dynamic Extinction in Metalized Solid Propellants)

  • 정호걸;이창진
    • 한국항공우주학회지
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    • 제31권2호
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    • pp.72-79
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    • 2003
  • 고체 추진제의 소화를 위한 연소실 압력 강하시 금속입자들에 의한 복사열전달에 동적소화에 미치는 영향을 알아보았다. AP:Binder의 화학반응으로 발생하는 전도열 플럭스를 구하기 위해 화염모델을 사용하였으며, 금속입자들에 복사열 플럭스를 구하기 위해 연소흐름 모델을 사용하였다. 연소실은 크기가 무한대인 경우와 노즐에 의해 제한된 형태 두 가지를 선택하여 계산을 수행하였다. 계산에 사용된 추진제 조성을 AP:Al:CTPB=76:10:14이며 최종압력 이후, 총 열 플럭스 중 복사열 플럭스가 차지하는 비중은 5~6%정도로 나타났다. 연소실 크기가 무한대인 경우, 복사열전달을 고려한 경우의 임계 압력강하율이 복하열을 고려하지 않은 경우보다 45% 크게 나타났다. 이는 복사열전달이 동적소화에 큰 영향을 미치는 것을 보여주는 것이다.

Preparation and Characterization of Screen-printed Lead Zirconate Titanate Thick Films

  • Lee Sung-Gap
    • Transactions on Electrical and Electronic Materials
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    • 제7권2호
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    • pp.72-75
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    • 2006
  • Ferroelectric PZT heterolayered thick films were fabricated by the alkoxide-based sol-gel method. PZT(Zr/Ti=60/40) paste was made and alternately screen-printed on the $Al_2O_3$ substrates. We have introduced a press-treatment to obtain a good densification of screen printed films. The porosity of the thick films was decreased with increasing the applied pressure and the thick films pressed at $0.6ton/cm^2$ showed the dense microstructure and thickness of about $76{\mu}m$. The relative dielectric constant increased with increasing the applied pressure. The remanent polarization and coercive field increased with increasing applied pressure and the values for the PZT thick films pressed at $0.6ton/cm^2$ were $16.6{\mu}C/cm^2$, 76.9 kV/cm, respectively.