• 대한의생명과학회지
• /
• 제13권3호
• /
• pp.183-187
• /
• 2007

Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) playa key role in development of atherosclerosis. To take into account the atherogenic properties of MCP-1 and IL-8 and its influence on insulin resistance, we examined circulating levels of MCP-1 and IL-8 in adults. We recruited 292 subjects (84 males and 208 females) aged between 29 and 79 years. MCP-1 and IL-8 levels were measured by enzyme-linked immunosorbent assay. Age, total cholesterol, HDL-cholesterol, and LDL-cholesterol levels were significantly higher in female subjects (P<0.01, respectively), but diastolic blood pressure (BP) was significantly lower in female subjects compared to male subjects. MCP-1 and IL-8 levels were tended to increase with age, the highest in their seventies. MCP-1 (P=0.05) and IL-8 (P<0.01) levels were higher in males than in females. MCP-1 was positively correlated with age (r=0.17, P<0.05), IL-8 (r=0.26, P<0.01), fasting insulin (r=0.30, P<0.01), and HOMA-IR (r=0.29, P<0.01). In linear regression analysis, age was found to be independent factor associated with MCP-1 adjusted by age, BMI, fasting glucose, triglyceride, and systolic BP. In conclusion, age was found to be independent factor associated with MCP-1. It is possible that an increase of MCP-1 in adults with age may be risk to atherosclerosis and diabetic properties.

• Imaging Science in Dentistry
• /
• 제53권2호
• /
• pp.91-99
• /
• 2023

Purpose: This systematic review aimed to investigate the correlation between chronological age and dental pulp volume in cone-beam computed tomography (CBCT). Materials and Methods: The literature was searched in 4 databases(PubMed, Scopus, Web of Science, and Google Scholar). Within each study, the outcome of interest was the correlation (r) between chronological age and pulp volume. A random-effect meta-analysis was conducted. Subgroup analysis was carried out according to sex and tooth type. Results: Of 5,693 identified studies, 27 fulfilled the inclusion criteria and were selected for meta-analysis. These articles focused on single-rooted teeth (n=21), multi-rooted teeth (n=6), maxillary teeth (n=14), mandibular teeth (n=6), and maxillary and mandibular teeth (n=12). The relationship between chronological age and dental pulp volume was examined in the entire population (r= -0.67), men (r= -0.75), and women (r= -0.77) in single- and multi-rooted teeth. The results of the total population analysis showed a relatively strong negative relationship between age and pulp volume. Conclusion: This study suggested that CBCT is a reliable and repeatable tool for dental age estimation. A strong inverse relationship was observed between pulp chamber volume and age. Further studies on the correlation between chronological age and pulp volume of multi-rooted teeth may be beneficial.

• 대한화장품학회지
• /
• 제30권1호
• /
• pp.85-91
• /
• 2004

본 연구는 30대 43명(I군), 40대 75명(II군), 50대 34명(III군) 등 총 152명의 한국 여성을 대상으로 본 연구에서 수립한 육안평가 기준과 기기를 이용하여 눈가(crow's feet)주름을 정량화 하였다. 육안평가 기준은 Modified Daniell's Criteria를 미세 변화를 관찰할 수 있도록 10단계로 세분화하여 이용하였고, 기기평가는 Transparency Profilometry 기법을 이용한 Skin Visiometer SV 600 (Courage + Kahzaka)을 적용하였다. 각 방법의 측정값으로 1) 연령군별 주름의 정도를 비교하였고, 2) 연령군별로 좌우측간의 주름의 정도를 비교해 보았으며, 3) 본 연구에 적용한 육안평가 점수와 기기평가의 5개 주름 파라미터인 Rl, R2, R3, R4, R5간의 상관성을 알아보았다. 육안평가 결과 연령이 증가할수록 육안평가 점수는 증가하였고, 각 연령군간에 통계적으로 유의한 차이가 관찰되었으나(P 〈 0.05), 모든 연령군에서 좌측과 우측의 육안평가 점수는 유의한 차이는 없었다. 기기평가 결과 연령이 증가할수록 5가지 주름 파라미터 모두 증가하는 경향을 보였고, 이중 연령군간 유의한 차를 보인 파라미터는 Rl, R4, R5 였으며 (P 〈 0.05), Rl과 R4는 I군과 III군 사이에 R5는 I군과 III군, II군과 III군 사이에서 유의한 차이를 나타내었다. 기기평가의 5가지 주름 파라미터 모두 좌우측간에 통계적으로 유의한 차이는 보이지 않았다(p 〈 0.05). 본 연구에 적용한 육안 평가 점수에 따라서 A군(0∼3 grade), B군(4∼6 grade), C군(7∼9 grade)으로 분류하여 기기평가 상의 5개 파라미터와의 상관성을 본 결과 R4와 R5가 A군다 C군 사이에 통계적으로 유의한 차이를 나타내었다(p 〈 0.05). 결과적으로 본 연구에서는 연령이 증가할수록 육안평가 점수와 5개의 주름 파라미터는 증가하였으나 좌우측간에 차이는 나타나지 않음을 알 수 있었다. 특히, 본 연구에서 적용한 육안평가 기준은 기기평가의 주름 파라미터 중 피부 주름의 평균 깊이와 피붜칠기를 나타내주는 R4와 R5를 더 정확히 반영함을 알수 있었고, 미세한 주름의 변화를 읽을 수 있음을 알 수 있었다.

• 대한감각통합치료학회지
• /
• 제3권1호
• /
• pp.49-56
• /
• 2005

Objective : The purpose of this study was to indicate the foundational data to standardize MVPT-R for Koreans. Method : This study was conducted on 221 children ranging in all preschool age from 4 to 6 years residing in Busan and Kyungsangnam-do. It was performed from January 12, 2004 to April 30, 2004. Result : First, similar to American children, as Korean children grow older, the mean raw score of MVPT-R increased. Second, Korean children's mean raw score was higher than that of American children; 3.51 in 4 age, 1.52 in 4.6 age, 2.93 in 5 age, 1.72 in 5.6 age, 1.84 in 6 age and 0.48 in 6.6 age. Third, the mean of PQ(106.57) in Korean children was higher than that of PQ in American children. Fourth, The raw score in Korean children was higher than the raw score in American children in most of the subjects(excluding visual closure subjects). Conclusion : The visual perception skill of Korean children is higher than that of American children. If we apply MVPT-R developed in U.S to Korean children, it will be difficult for Korean children to achieve the adequate results. Therefore, we must use the standardized MVPT-R for Korean that can minimize the differences between American and Korean children's visual perception skills.

• 대한지역사회영양학회지
• /
• 제8권6호
• /
• pp.993-1000
• /
• 2003

The purpose of this study was to provide baseline data for revising the recommended energy intake for Korean adults. We recruited 290 adults so as to determine their resting energy expenditure (REE) and energy intake. The REE was measured by indirect calorimetry. We also calculated the REE from prediction equations formulated by World Health Organization (WHO), The energy intake for two consecutive days was assessed using the 24 hour recall method. The body weight, lean body mass (LBM) and percentage body fat were measured using the INBODY 3.0 system. We compared the results of three age groups ; 20 to 29 years,30 to 49 years and 50 years or more. The average energy intake of each age group was below the 7th Korean Recommended Dietary Allowances (RDA). The average energy intake was lower in the older age groups. However, no difference was observed among the age groups when the energy intake as a percentage of the Korean RDA was compared. Our measurement of the REE was higher than the REE calculated by the WHO's method. Correlation coefficients between the measured and the calculated values of REE for all age groups showed significant correlations (r=0.475-0.672). As the ages of all the subjects increased, the REE/kg of body weight decreased. There were no significant differences in the REE / kg of the LBM between the different age groups; however, the REE/kg of the LBM was higher in the female group than in the male group. Negative correlations of the REE with the age (r=-0.242) and body fat ratio (r=-0.313) were observed; positive correlations of the REE with the BMI (r=0.265), height (r=0.570), weight (r=0.562) and LBM (r=0.586) were also found (p<0.01).

• 대한지역사회영양학회지
• /
• 제15권3호
• /
• pp.403-414
• /
• 2010

Reducing women's bone mineral density (BMD) has close relationship to risk in osteoporosis. This study was carried out to identify bone density risk factors affecting women's BMD, and to analyze the relationship of age, between BMD and menopause, BMI, blood pressure lifestyle and dietary habits for bone health by physical measurement and questionnaires. The study subjects, 128 women living in Seoul, were divided into 4 age group; 30~39 years (17), 40~49 years (54) and 50~59 years (36) and 60~69 years (21). There were significant differences in mean height, BMI, systolic blood pressure, menache and menopause age and menopause ratio and BMD T-score among the 4 age groups. BHD was significantly decreased according to increasing age and BMI and menopause. The rate of BMD risk subjects was significantly different increasing with age and BMI. The rate of risk group were 0%, 13%, 22.2% and 71.4%, by age groups and 0%, 16.2%, 33.3% and 52.9% by BMI respectively. BMD of menopause groups was significantly decreased from 1.23 (40 years) to 1.34 (60 years). p < 0.001. Also systolic blood pressure were significantly increased from 116.5 mmHg (30 years) to 130.81 mmHg (60 years). The T-score of normal group also decreased significantly from 1.27 to 0.13 (60years) with age. There were significant negative correlation between BMD and age (r = -0.409) menopause (r = -0.346), BMI (r = -0.218) systolic blood pressure (r = -0.193), salty taste eating out (r = -0.185) (p < 0.05). There were significant positive correlation between BMD and meat fish and walking time. In conclusion, bone density decreased with age. Most of the 50 years' subjects were in risk group. BMI, menopause, systolic blood pressure, frequency alcohol consuming. To prevent osteoporosis, over 40 years needed to be educated to maintain normal weight and the improvement of eating and living habits.

• 한국전산구조공학회:학술대회논문집
• /
• 한국전산구조공학회 2006년도 정기 학술대회 논문집
• /
• pp.97-103
• /
• 2006

A modified one-sided measurement technique is proposed for Rayleigh wave (R-wave) velocity measurement in concrete. The scattering from heterogeneity may affect the waveforms of R-waves in concrete, which may make the R-waves dispersive. Conventional one-sided techniques do not consider the scattering dispersion of R-waves in concrete. In this study, the maximum energy arrival concept is adopted to determine the wave velocity by employing its continuous wavelet transform. Experimental study was performed to show the effectiveness of the proposed method. The present method is applied to monitor the strength development of early-age concrete. A series of experiments were performed on early-age concrete specimens with various curing conditions. Results reveal that the proposed method can be effectively used to measure the R-wave velocity in concrete structures and to monitor the strength development of early-age concrete.

• 약학회지
• /
• 제36권5호
• /
• pp.460-468
• /
• 1992

Several bichemical parameters related to free radicals were estimated in senile-prone (P) and resistant(R) strains of male senescence-accelerated mice(SAM) at 2, 5 and 11 months of age. The superoxide generation was increased with age in SAM-R/1 and SAM-P/2. Compared to SAM-R/1, more generation of superoxide was significantly noted in the SAM-P/2 liver. The activities of Cu/Zn-superoxide dismutase and catalase were decreased during aging and these activities in SAM-P/2 were significantly lower than in SAM-R/l liver. The activities of glutathione S-transferase were varied with aging, whereas SAM-P/2 showed lower levels compared to SAM-R/l. The gradual decreases of glutathione, protein bound-SH and nonprotein bound-SH contents were noted with increasing age. SAM-P/2 liver contained lesser amounts of glutathione and nonprotein bound-SH compared to SAM-R. In conclusion, superoxide generation was increased whereas the antioxidant enzyme activities were decreased during aging in SAM-R/1. In addition, SAM-P/2 strain showed more superoxide generation and less antioxidant enzyme activities than SAM-R/1 in the liver, thus we assume that these factors might accelerate the senescence of SAM-P/2 strain.

• Child Health Nursing Research
• /
• 제9권3호
• /
• pp.294-300
• /
• 2003

Purpose: The purpose of the study was to investigate the status of visual health behavior of school-age children and to identify the predicting variables of the school-age children's visual health behavior. Method: The subject was 764 children in grades 4 to 6, enrolled in 2 elementary schools located in urban area. The data were analyzed using t-test, ANOVA, correlation analysis, and stepwise multiple regression. Result: The findings were as follows: 1. The mean of the score of the visual health behavior of school-age children was 41.59(SD=7.22) and there was a significant difference according to grade. 2. There were significant correlations between visual health behavior and self-efficacy for visual health behavior (r=.51, p=.000), motivation for visual health(r=.45, p=.000), perceived benefits(r= .34, p=.000), self-concept(r=.32, p=.000), knowledge of visual health(r=.30, p=.000), health perception for vision(r=.16, p=.000), health locus of control(r=.11, p=.002), and perceived barriers(r=.-.12, p=.000). 3. Self-efficacy for visual health behaviors, knowledge of visual health, motivation for visual health, self-concept, health perception for vision, and perceived benefits were identified as predictor variables of the visual health behavior of the school-age children from the stepwise multiple regression analysis. The total percent of variance accounted by these 6 variables were 36.9％. Conclusion: From the result, it is suggested that the development of comprehensive visual health education program including the component of self-efficacy, health motivation and self-concept to promote the visual health of school-age children.

• 한국정보전자통신기술학회논문지
• /
• 제10권4호
• /
• pp.279-287
• /
• 2017

The aim of this study is to verify the difference in the level of happiness and preparation for old age according to the general characteristics of senior welfare center attendees. The subjects of the study were 148 attendees of OO senior welfare center in Seoul and a survey was conducted from July 4 to October 7, 2016. The method of analysis was by using the SPSSWIN 18.0 program, a 5% level of significance was verified in a frequency analysis, t-test, one-way ANOVA, correlation analysis, and multiple regression analysis. The results showed that first, from investigating the difference in the level of preparation for old age according to general characteristics, there was a significant difference according to age, occupation, monthly income, and physical condition but there was no significant difference according to gender and level of education. Second, as a result of observing the difference in the level of happiness according to general characteristics, although there was a significant difference according to occupation and monthly income, the difference level according to gender, age, level of education, health condition was less than a 5% level of significance. Third, from observing the correlation between the level of happiness and preparation of old age, it was found that happiness was positively correlated to preparation for old age in the following order: physical preparation for old age ((r=.576, p<.001), economic preparation for old age (r=.570, p<.001), psychological preparation for old age (r=.526, p<.001), social preparation for old age (r=.525, p<.001). It is forecasted that this study will be used as base line data for improvement of happiness and preparation for old age for the elderly according to general characteristics.