• 제목/요약/키워드: AGE-R

검색결과 3,624건 처리시간 0.026초

Testicular Cell Indices and Peripheral Blood Testosterone Concentrations in Relation to Age and Semen Quality in Crossbred (Holstein Friesian×Tharparkar) Bulls

  • Rajak, S.K.;Kumaresan, A.;Gaurav, M.K.;Layek, S.S.;Mohanty, T.K.;Aslam, M.K. Muhammad;Tripathi, U.K.;Prasad, Shiv;De, S.
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권11호
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    • pp.1554-1561
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    • 2014
  • Present study analyzed the changes in peripheral blood testosterone concentrations and testicular cytogram in relation to age and semen quality in crossbred males. Three different age groups of crossbred males viz. bull calves (6 months, n = 5), young bulls (15 months, n = 5) and adult bulls (4 to 6 years, n = 8) were utilized for the study. Testicular fine needle aspiration cytology technique was used to quantify testicular cytology and their indices. Peripheral blood testosterone concentrations were measured using enzyme-linked immunosorbent assay method. Semen samples collected from adult bulls were microscopically evaluated for quality parameters. Mean peripheral blood testosterone concentrations in bull calves, young bulls and adult bulls were $2.28{\pm}0.09ng/mL$, $1.42{\pm}0.22ng/mL$ and $5.66{\pm}1.08ng/mL$ respectively, and that in adult bulls were significantly different (p<0.01) from young bulls and bull calves. There was no significant difference between the proportion of different testicular cells in bull calves and young bulls. Between young and adult bulls, significant differences (p<0.01) were observed in the proportion of spermatocytes, spermatozoa, and sperm: Sertoli cell ratio. The proportions of Sertoli cells showed a significant difference (p<0.01) between the three age groups. The number of primary spermatocytes had a positive correlation with peripheral blood testosterone concentrations in bull calves (r = 0.719, p<0.01). Number of Sertoli cells per 100 germ cells was negatively correlated with blood testosterone concentration in young bulls (r = -0.713, p<0.01). Among different semen parameters in adult bulls, ejaculate volume (r = 0.790, p<0.05) had positive relationship, and sperm motility had significant negative correlation (r = -0.711, p<0.05) with testosterone concentrations. The number of Sertoli cells and Sertoli cell index had a positive correlation with various semen quality parameters (p<0.001). Results of the present study conclude that number of Sertoli cells and Sertoli cell index are good indicators of semen quality, but peripheral blood testosterone concentrations may not have a direct relationship with various seminal attributes in crossbred bulls.

한국 서해안 갈색띠매물고둥, Neptunea (Barbitonia) arthritica cumingii의 연령과 성장 (Age and Growth of the Neptunea (Barbitonia) arthritica cumingii in the West Sea of Korea)

  • 안정은;최종덕;류동기
    • 한국패류학회지
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    • 제30권1호
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    • pp.25-32
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    • 2014
  • 본 연구는 2007년 10월부터 2008년 9월까지 전라북도 군산시 고군산군도에서 통발어구로 채취된 갈색띠매물고둥을 조사하였다. 갈색띠매물고둥의 뚜껑에 나타난 윤문은 년 1회 형성되며 주 윤문 형성시기는 7월에서 8월로 조사되었으며, 초륜 형성기간은 12개월 (1년) 로 나타났다. 각고 (SH) 에 대한 각폭 (SW) 의 성장식은 SW = 0.5757 SH + 0.222 ($R^2$ = 0.8723), 총중량 (TW) 의 상대성장식은 TW = 0.0002 $SH^{2.8162}$ ($R^2$ = 0.9121) 과 같이 나타낼 수 있었다. 연령 (t) 에 대한 각고 (SH) 와 총중량 (TW) 의 von Bertalanffy 성장식은 다음과 같다. $$SH_t=173.964(1-e^{-0.164(t+1.173)})$$ $$TW_t=407.952(1-e^{-0.164(t+1.173)})^{2.8162}$$

어머니의 영유아에 대한 애착에 영향을 미치는 요인 -영유아와 어머니의 특성, 사회적 지지, 모아상호작용을 중심으로- (Factors Influencing Maternal Attachment to Infant-Toddler -Focusing on Infant-Toddler and Maternal Characteristics, Social Support and Mother-Child Interaction-)

  • 황영희;박선정
    • 한국산학기술학회논문지
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    • 제19권6호
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    • pp.231-239
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    • 2018
  • 본 연구의 목적은 영유아와 어머니의 일반적 특성, 사회적 지지 그리고 모아상호작용이 모아애착에 미치는 영향을 분석하는 것이다. 본 연구는 서술적 조사연구로 자료수집기간은 2016년 3월 1일부터 9월 30일까지였다. 영유아기의 자녀가 있는 어머니 215명을 대상으로 자가 보고형 설문지를 이용하여 일반적 특성, 사회적 지지, 모아상호작용 그리고 애착에 대한 자료를 수집하였다. 수집된 자료는 SPSS 24.0 프로그램을 이용하여 기술통계, 집단간 평균비교, 상관관계 그리고 다중회귀분석으로 분석하였다. 연구결과 영유아의 특성 중 성별(t=3.200, p<.002), 연령(t=4.037, p<.001)과 기질(F=4.614, p<.011)에 따라, 어머니의 특성 중 연령(F=18.028, p<.001)과 학력(F=4.241, p<.016)에 따라 애착의 평균값이 통계적으로 유의한 차이가 있었다. 애착은 사회적 지지(r=.507, p<.001) 및 모아상호작용(r=.571, p<.001)과 통계적으로 유의한 양의 상관관계가 있었다. 애착에 영향을 미치는 요인은 모아상호작용(${\beta}=0.361$, p<.001), 사회적 지지(${\beta}=0.309$, p<.001), 연령(30세미만)(${\beta}=-0.370$, p<.001) 그리고 결혼 기간(10년 미만)(${\beta}=-0.179$, p<.033)이었다. 애착에 중요한 영향을 미치는 사회적 지지와 모아상호작용을 높일 수 있는 중재 프로그램 개발이 필요할 것으로 생각된다.

스켈링 실습실 방문자의 구강건강행위에 관한 연구 (A study on the oral health behavior of oral prophylaxis clients)

  • 장계원;강용주;정미경
    • 한국치위생학회지
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    • 제10권6호
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    • pp.1083-1093
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    • 2010
  • Objective : The purpose of this study was to examine the relationship of the oral health behavior of oral prophylaxis clients and some residents in a community to their simplified oral environment index. Methods : The subjects in this study were 520 people who had their teeth cleaned in the oral prophylaxis practice lab in the department of dental hygiene at J health college. A survey was conducted from March 23 to June 3, 2010, by way of the self-reported questionnaire. The data materials are analyzed by general characteristics frequency and ratio, the relationship of oral health behavior and sex, age, scaling experience, simplified oral hygiene index $x^{2}$ test analysis. Results : 1. Concerning links between gender and oral health behavior including daily toothbrushing frequency, the largest group of the respondents brushed their teeth three times a day(p<0.05). As to educational experiences on toothbrushing method and the use of oral hygiene supplies, the women had more educational experiences than the men(p<0.05). 2. Regarding connections between age and oral health behavior involving daily toothbrushing frequency, the largest number of the respondents brushed their teeth three times a day in every age group (p <0.001). As for educational experiences on toothbrushing method, those who were in their 50s and up(64.7%) learned about that, and they had more educational experiences with age(p<0.05). As for scaling experiences, the older respondents had their teeth scaled more often (p<0.001). 3. As to relationship between scaling experiences and oral health behavior, there were differences in toothbrushing frequency according to scaling experiences(p <0.05). Regarding educational experiences on toothbrushing method, those who had their teeth cleaned received more toothbrushing education(p<0.001). Concerning smoking, the nonsmokers had more experiences to get their teeth cleaned (p<0.001). 4. As for links between simplified oral environment index and oral health behavior including a time for toothbrushing, the respondents who did toothbrushing after every meal(80.4%) had good simplified oral environment indexes(p<0.05). 5. In regard to relationship between simplified oral environment index and oral health behavior, oral environment index had a positive correlation to the use of oral hygiene supplies( r=0.129**), toothbrushing time(r=0.116**) and educational experiences on toothbrushing method (r=0.099**). Smoking(r=-0.092**) had a negative correlation to that. Conclusion : The above-mentioned findings illustrate that oral health behavior is one of crucial factors to affect oral health status and oral environment care. Therefore oral prophylaxis practice lab visitors should receive education on the right toothbrushing method and the use of oral hygiene supplies to promote their oral health, and an incremental oral health care system that involves regular scaling should be introduced.

노인의 불명확한 사망원인진단 관련요인 분석과 개선방안 (Analysis and Improving ways of Factors affecting the Ill-defined Causes of Death of the Aged in Korea)

  • 박상희;이태용
    • 보건행정학회지
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    • 제21권2호
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    • pp.329-348
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    • 2011
  • This research analyzed 168,010 cases of death of the aged over 65 from 244,867cases of death excluding 7 unknown age cases from 244,874 all age cases of death by using the death data of the National Statistical Office for 2007 to figure out factors affecting the quality of causes of death statistics of the aged and to suggest the ways of improving the quality of death statistics of the aged in korea. This research tried to derive factors affecting ill-defined cause of death category in acordance with WHO's guidelines and to find causes of lowering the accuracy of causes of death statistics of the aged. This research identified the problems of causes of death statistics of the aged by using both demographic characteristics such as sex, age, marital status, educational attainment, residential region, region size and factors of death items as independent variable to find causes of ill-defined cause of death of the aged. Logistic regression analysis was executed to calculate the hazard ratio about the ill-defined causes of death of the aged and multiple regression analysis was conducted to derive factors affecting the ill-defined cause of death by regional groups through using these independent variables such as the component ratio of over age 65, female death rates, doctors insitutions rate, medical institutions rate, attaching rates of death certificate by neighborhood. As a results of this research, R-code was the highest of ill-defined causes of death, accounting for 82.1%, and senility death(R54) of R-code was the highest, accounting for 91.2%. through subdivided order distribution of the ill-defined causes of death of the aged. As ill-defined causes of death by regional groups, attaching rates of death certificate by neighborhood was the most important factor(p<0.05) and also showed regression model's description with 83.8% ($R^2$=83.8%). Furthermore, Jeon-nam was the highest in the regional groups and these regions such as Je-ju, Jeon-buk, Chung-nam were not only attaching the death certificate by neighborhood but also were high at the rate of ill-defined causes of death. Therefore, this research found that both reconsideration about death certificate by neighborhood and education for doctors who write death certificate were needed the most.

Development of the Korean Developmental Screening Test for Infants and Children (K-DST)

  • Chung, Hee Jung;Yang, Donghwa;Kim, Gun-Ha;Kim, Sung Koo;Kim, Seoung Woo;Kim, Young Key;Kim, Young Ah;Kim, Joon Sik;Kim, Jin Kyung;Kim, Cheongtag;Sung, In-Kyung;Shin, Son Moon;Oh, Kyung Ja;Yoo, Hee-Jeong;Yu, Hee Joon;Lim, Seoung-Joon;Lee, Jeehun;Jeong, Hae-Ik;Choi, Jieun;Kwon, Jeong-Yi;Eun, Baik-Lin
    • Clinical and Experimental Pediatrics
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    • 제63권11호
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    • pp.438-446
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    • 2020
  • Background: Most developmental screening tools in Korea are adopted from foreign tests. To ensure efficient screening of infants and children in Korea, a nationwide screening tool with high reliability and validity is needed. Purpose: This study aimed to independently develop, standardize, and validate the Korean Developmental Screening Test for Infants and Children (K-DST) for screening infants and children for neurodevelopmental disorders in Korea. Methods: The standardization and validation conducted in 2012-2014 of 3,284 subjects (4-71 months of age) resulted in the first edition of the K-DST. The restandardization and revalidation performed in 2015-2016 of 3.06 million attendees of the National Health Screening Program for Infants and Children resulted in the revised K-DST. We analyzed inter-item consistency and test-retest reliability for the reliability analysis. Regarding the validation of K-DST, we examined the construct validity, sensitivity and specificity, receiver operating characteristic curve analysis, and a criterion-related validity analysis. Results: We ultimately selected 8 questions in 6 developmental domains. For most age groups and each domain, internal consistency was 0.73-0.93 and test-retest reliability was 0.77-0.88. The revised K-DST had high discriminatory ability with a sensitivity of 0.833 and specificity of 0.979. The test supported construct validity by distinguishing between normal and neurodevelopmentally delayed groups. The language and cognition domain of the revised K-DST was highly correlated with the K-Bayley Scales of Infant Development-II's Mental Age Quotient (r=0.766, 0.739), while the gross and fine motor domains were highly correlated with Motor Age Quotient (r=0.695, 0.668), respectively. The Verbal Intelligence Quotient of Korean Wechsler Preschool and Primary Scales of Intelligence was highly correlated with the K-DST cognition and language domains (r=0.701, 0.770), as was the performance intelligence quotient with the fine motor domain (r=0.700). Conclusion: The K-DST is reliable and valid, suggesting its good potential as an effective screening tool for infants and children with neurodevelopmental disorders in Korea.

Praat과 R로 분석한 한국인 대화 음성 말뭉치의 fundamental frequency(f0)값 분포 (The fundamental frequency (f0) distribution of Korean speakers in a dialogue corpus using Praat and R)

  • 양병곤
    • 말소리와 음성과학
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    • 제15권3호
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    • pp.17-25
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    • 2023
  • 이 논문은 국립국어원에서 배포한 한국인 대화 음성 말뭉치에서 화자의 성대의 진동을 나타내는 fundamental frequency(f0)값을 측정해서 한국인이 일상 대화를 할 때 f0값의 기초적인 통계자료를 살펴보고, 나이와 f0값의 분포는 어떤 관계를 보이는지를 조사했다. 연구자료 수집과 분석은 Praat과 R을 이용했고, 개인별 억양구마다 상자도를 구하고 사분위값을 활용하여 극단값을 제거하는 방법으로 최종 f0값 자료를 구했다. 그 결과 전체 한국인들의 f0값의 평균값은 185 Hz이고 중앙값은 187 Hz로 나왔다. 자료의 분포모양을 나타내는 왜도는 0.11의 정적분포를 보였고, 첨도는 -0.09로 정상분포에 거의 가까운 모양을 보였다. 일상대화의 피치값의 변화범위로는 238 Hz로 나타났다. 남녀 간의 f0값의 차이는 남성의 중앙값 114 Hz의 거의 두 배에 해당하는 199 Hz가 여성의 중앙값으로 나타났고 t검증결과 유의미한 차이를 보였다. 분포모양을 나타내는 왜도는 남성이 1.24이었고, 여성은 그것의 반에 해당하는 0.58이었다. 첨도는 남녀집단 각각 5.21과 3.88로 나타나 남성의 값이 34% 정도 더 뾰족한 모양을 보였다. 연령대별로는 남녀집단을 합하여 볼 때, 나이가 들수록 f0값이 서서히 내려가는 경향을 보였다. 연령대별 f0중앙값과 나이 간의 회귀분석을 실행한 결과 기울기가 남성집단에서는 0.15, 여성집단에서는 -0.586으로 서로 반대되는 경향을 기록했다. 결론적으로, 대규모 참여자가 녹음한 대화 음성에서 한국인의 집단별 연령별 다양한 f0분포를 규명할 수 있지만, 나이와 f0관계는 더 정밀한 자료수집이 필요함을 알 수 있었다.

한우의 체중 성장곡선 모수 추정을 위한 체중 측정 자료의 최적 범위에 관한 연구 (Study on the Optimum Range of Weight-Age Data for Estimation of Growth Curve Parameters of Hanwoo)

  • 조용민;윤호백;박병호;안병석;전병순;박영일
    • Journal of Animal Science and Technology
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    • 제44권2호
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    • pp.165-170
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    • 2002
  • 본 연구는 한우의 성장형태 분석을 위한 성장곡선 모수 추정시 이용하는 체중 측정자료의 최적 월령을 결정하기 위해 실시하였다. 분석에 이용한 자료는 농협 한우개량부에서 사육된 한우 수소 1,133두의 일령별 체중자료를 이용하였으며, 비선형 회귀모형인 Gompertz 모형으로 성장곡선을 추정하였다. 24개월까지 측정한 자료에 대해 14개월부터 2개월 단위로 최종 자료입력 시기를 분할한 6개의 측정종료 월령별 체중자료에 대해 추정한 성장곡선 모수 가운데 성숙체중(A)은 22개월령과 24개월령의 추정치 평균간 차이에 유의성이 없었으며, 성숙률(k) 추정치는 18-24개월령의 추정치 평균간 차이가 유의성이 없는 것으로 나타났다.(p$<$0.05). 측정종료 월령별 성숙체중(A) 추정치간의 상관 계수는 22개월령과 24개월령간에 0.93으로 가장 높게 나타났으며, 성숙률(k) 추정치간의 상관계수는 18-24개월령간에 0.91-0.99로 높게 나타났다(p$<$0.05). 성숙체중과 성숙률 추정치간의 상관은 12개월령의 경우 0.84로 높게 추정되었으나, 22개월령과 24개월령의 경우 0.12 및 0.10으로 추정되어 체중자료의 최종입력 시기가 연장됨에 따라 추정 모수간의 상관이 낮아지는 것으로 나타났다. 따라서 한우의 체중 성장 형태를 분석하기 위한 성장곡선 추정을 위한 자료의 최종 입력시기의 최적 월령은 22개월령 이상으로 사료된다.

적정체중아 제대혈의 ghrelin 및 leptin 농도와 신체계측치의 관계 (Correlations of cord blood Ghrelin and leptin concentrations with anthropometry of appropriate for gestational age newborns)

  • 이진;문세나;박소현;정민호;서병규;이병철
    • Clinical and Experimental Pediatrics
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    • 제49권1호
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    • pp.93-98
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    • 2006
  • 목 적 : 재태연령 34주 이상의 적정체중아(appropriate for gestational age, AGA)에서 제대혈의 ghrelin과 leptin의 농도를 측정하고 출생체중, 체질량지수(body mass index, BMI) 등의 신체계측치와의 연관성 및 IGF-I, IGFBP-3와 같은 성장과 관련된 호르몬과의 관계에 대해 알아보았다. 방 법 : 재태연령 34주에서 42주 미만의 신생아 중 재태기간과 비교해 적정체중을 가진 건강한 남아 31명과 여아 29명을 대상으로 하였다. 대상 신생아의 출생체중, 체질량지수를 계측하고 제대정맥혈을 채취하여 ghrelin, leptin, IGF-I 및 IGFBP-3 농도를 측정하여 분석하였다. 결 과 : 대상 신생아들의 제대혈에서 ghrelin 농도($528.3{\pm}307.3pg/mL$)는 신생아의 출생체중(r=-0.29, P<0.05)과 재태연령(r=-0.28, P<0.05)과 반비례하였다. 한편, 대상 신생아 제대혈의 leptin 농도($4.43{\pm}3.66ng/mL$)는 신생아의 출생체중(r=0.44, P<0.01), 재태연령(r=0.36, P<0.01), 체질량지수(r=0.28, P<0.05) 등과 비례하였다. 제대혈의 ghrelin 농도는 성별에 따른 차이가 없었으나 leptin 농도는 여아($5.45{\pm}4.32ng/mL$)에서가 남아($3.48{\pm}2.64ng/mL$)에서보다 유의하게 높았으며(P<0.05), 특히 재태연령 37주 이상인 군에서 성별에 따라 뚜렷한 차이를 보였다(P<0.01). 제대혈의 ghrelin과 leptin 농도 사이에서는 의미있는 상관관계가 없었으며, ghrelin 농도와 제대혈의 IGF-I 및 IGFBP-3 사이에서도 역시 의미있는 상관관계가 없었다. 결 론 : 적정체중을 가진 신생아의 제대혈 ghrelin 농도는 출생체중 및 재태연령에 반비례하였다. 제대혈의 leptin 농도는 신생아의 출생체중, 재태연령 및 체질량지수 등의 신체계측치에 비례하였으며 여아에서 남아에서보다 더 높은 농도를 나타냈다. 제대혈의 ghrelin과 leptin 농도 사이에는 특별한 상관관계가 없었다. 앞으로 이들 물질이 태아 성장에 생리적, 병리적으로 상호 어떤 역할을 하는지 규명하기 위해 더 많은 연구가 필요할 것으로 생각된다.

Age Estimation Based on Mandibular Premolar and Molar Development: A Pilot Study

  • Roh, Byung-Yoon;Kim, Eui-Joo;Seo, In-Soo;Kim, Hyeong-Geon;Ryu, Hye-Won;Lee, Ju-Heon;Seo, Yo-Seob;Ryu, Ji-Won;Ahn, Jong-Mo
    • Journal of Oral Medicine and Pain
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    • 제46권4호
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    • pp.125-130
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    • 2021
  • Purpose: The dental age estimation of children is performed using dental maturity. Postmortem missing of the anterior teeth or the distortion of image of the anterior teeth in panoramic radiographs can make it difficult to analyze the development of the anterior teeth. This pilot study was conducted to derive a new age estimation method based only on the developmental stage of mandibular posterior teeth. Methods: This study was conducted using panoramic radiographs of 650 subjects aged 3 to 15 years old. The dental developmental stages of the lower left first premolar, second premolar, first molar and second molar were evaluated according to the Demirjian's criteria. The intra-/inter-observer reliability was evaluated, and multiple linear regression analyses were performed including the developmental stage of each tooth as an independent variable. Results: The intra-/inter-observer reliability was 0.9626 and 0.8877, respectively, and showed very high reproducibility. Multiple linear regression analyses were performed for males and females, and the age calculation table was derived by obtaining the intercept and the coefficient according to the development stage of each tooth. The coefficient of determination (r2) of the age calculation method was 0.9634 for male and 0.9570 for female subjects, and the mean difference between chronological age and estimated dental age was -0.42 and -0.21, respectively. Conclusions: This pilot study evaluated the developmental stages of four lower posterior teeth in the Korean group according to Demirjian's criteria, and derived age estimation method. The accuracy was lower than when more teeth were used, but it will be useful to estimate age of children when the anterior teeth are difficult to accurately analyze.