• Journal of the Korean Society of Radiology
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• v.5 no.1
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• pp.37-49
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• 2011

To examine the possible changes in the SNRs, CNRs, and ADC values for lumbar spines with metastasis based on the DW images before and after contrast agent injection taken from metastatic spinal cancer patients using a 1.5 T MR machine. The quantitative analysis revealed that in case of spinal cancer subjects, both SNRs and CNRs at all of those assessed locations significantly increased on the DWI after contrast agent injection compared to before, while on the ADC map images, SNRs significantly decreased. On the other hand, significantly decreased ADC values at all the assessed locations were found on the ADC map images. With reference to the normal group, significantly increased SNRs were found at all of the assessed locations on the DWI image after injection compared to before, while significantly decreased SNRs were found on the ADC map images. Also, significantly decreased ADC values at all the assessed locations were found on the ADC map images. For the qualitative analysis, after contrast agent injection, significantly increased signal intensities were found at the locations with spinal cancer on the DWI. In contrast, significantly decreased signal intensities were found on the ADC map images. The implication from the results showing that SNR and CNR significantly increased while ADC value significantly decreased at, above, and below the location of metastatic spinal cancer on DWI after contrast agent injection is that DWI obtained after contrast agent injection can be made available for wider application to vertebral disorders.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.15 no.6
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• pp.467-474
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• 1990

In this paper, the circuit that has characteristics of high speed and low dissipation is described. A 4:1 parallel ADC is constructed by using the designed SCFL(Source Coupled FET Logic). The results of simulation shows that comparators is obtained integrated nonlinearity, $\pm$28mV, compared with limiting value, $\pm$68mV, at 66NHz input signal and 2Gs/s Niquist rates and this paper describes low power dissipation about 0.43W by reducing the elements in a ADC design.

• Investigative Magnetic Resonance Imaging
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• v.25 no.2
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• pp.118-128
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• 2021

Purpose: To investigate the value of MR textural analysis, including use of diffusion-weighted imaging (DWI) to differentiate malignant from benign soft-tissue tumors on 3T MRI. Materials and Methods: We enrolled 69 patients (25 men, 44 women, ages 18 to 84 years) with pathologically confirmed soft-tissue tumors (29 benign, 40 malignant) who underwent pre-treatment 3T-MRI. We calculated MR texture, including mean, standard deviation (SD), skewness, kurtosis, mean of positive pixels (MPP), and entropy, according to different spatial-scale factors (SSF, 0, 2, 4, 6) on axial T1- and T2-weighted images (T1WI, T2WI), contrast-enhanced T1WI (CE-T1WI), high b-value DWI (800 sec/mm²), and apparent diffusion coefficient (ADC) map. We used the Mann-Whitney U test, logistic regression, and area under the receiver operating characteristic curve (AUC) for statistical analysis. Results: Malignant soft-tissue tumors had significantly lower mean values of DWI, ADC, T2WI and CE-T1WI, MPP of ADC, and CE-T1WI, but significantly higher kurtosis of DWI, T1WI, and CE-T1WI, and entropy of DWI, ADC, and T2WI than did benign tumors (P < 0.050). In multivariate logistic regression, the mean ADC value (SSF, 6) and kurtosis of CE-T1WI (SSF, 4) were independently associated with malignancy (P ≤ 0.009). A multivariate model of MR features worked well for diagnosis of malignant soft-tissue tumors (AUC, 0.909). Conclusion: Accurate diagnosis could be obtained using MR textural analysis with DWI and CE-T1WI in differentiating benign from malignant soft-tissue tumors.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1197-1203
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• 2014

Background: Adenocarcinoma (ADC) is the most common histological type of lung cancer and its proportion is rising, especially in Asian non-smoking women. Recent studies suggest miR-25 may have diverse effects on the pathogenesis of different types of cancer. However, the role of miR-25 in lung cancer is still unknown. The aim of this study was to investigate the potential clinical value of miR-25 in non-smoking women with lung ADC. Patients and Methods: Quantitative RT-PCR was performed to evaluate the expression of miR-25 in 100 lung ADC tumor tissues and matched plasma samples and Pearson correlation tests were used to analyze the relationship between values. Associations of miR-25 expression with clinicopathological features were determined using the Student's t-test. To determine prognostic value, overall survival (OS) was evaluated using the Kaplan-Meier method. Univariate and multivariate analyses were performed using the Cox proportional hazard model. Results: Expression of miR-25 in tissue was found to be associated with lymph node metastasis (P=0.021) and disease stage (P=0.012). Moreover, high miR-25 expression was also associated with poorer overall survival of women with lung ADC (P=0.008). Conclusion: Tissue miR-25 expression may be associated with tumor progression and have prognostic implications in female lung ADC patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.6
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• pp.1402-1409
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• 2007

In this paper, we propose various types of AGC algorithms for implementing the OFDM communication systems. For the high-speed packet transmission, in this paper, we assume the OFDM system with relatively long and repeated preambles. We propose the maximum sample value counter for counting the number of maximum sample. In the maximum sample value counter, we use the buffer for the digital signal buffering. Finally, the counting value of the maximum sample value counter controls the gain control signal generator by using gain control table automatically.

• Journal of Sensor Science and Technology
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• v.26 no.3
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• pp.155-159
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• 2017

The analog-to-digital converter (ADC) is an important component in various fields of sensor signal processing. This paper presents an expandable flash analog-to-digital converter (E-flash ADC) for sensor signal processing using a comparator, a subtractor, and a multiplexer (MUX). The E-flash ADC was simulated and designed in $0.35-{\mu}m$ standard complementary metal-oxide semiconductor (CMOS) technology. For operating the E-flash ADC, input voltage is supplied to the inputs of the comparator and subtractor. When the input voltage is lower than the reference voltage, it is outputted through the MUX in its original form. When it is higher than the reference voltage, the reference voltage is subtracted from the input value and the resulting voltage is outputted through the MUX. Operation of the MUX is determined by the output of the comparator. Further, the output of the comparator is a digital code. The E-flash ADC can be expanded easily.

• Journal of Advanced Navigation Technology
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• v.3 no.1
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• pp.52-59
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• 1999

Digital microwave wideband receiver including linear amplifier, analog-to-digital converter(ADC) and digital signal processor is able to analyze its performance using sensitivity and dynamic range of system. Determination of gain, third-order intermodulation products and ADC characteristics and design criteria for the linear amplifier chain is essential problem for sensitive and dynamic range. Also, if there are two signals with frequencies very close, digital signal processor must be able to separate the two signals. In this paper, we measured dynamic range as gain was changed and determined gain value for the proper sensitivity and dynamic range and high resolution spectrum estimation was used to separate two close signals.

• Journal of Korean Neurosurgical Society
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• v.38 no.1
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• pp.23-27
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• 2005

Objective : The aim of this study is to assess the significance of an apparent diffusion coefficient[ADC] study for diagnosis of ventriculitis. Methods : Seven patients with ventriculitis were enrolled in this study. Diffusion-weighted[DW] magnetic resonance images[MRI] and ADC maps in the dependent intraventricular collection, periventricular white matter and non-dependent cerebrospinal fluid[CSF] were obtained. The images and ADC data from the different lesions were compared. Results : The DW MRI showed marked hyperintensity in the purulent pus lesion, and the corresponding ADC maps revealed prominent hypointensity and restricted ADC values compared with the non-dependent CSF and normal white matter. Conclusion : The decreased ADC value and increased signal intensity of the dependent intraventricular fluid on the DW MRI show restricted water diffusion in the purulent fluid, which is indicative of a pyogenic ventriculitis diagnosis.

• Journal of Advanced Navigation Technology
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• v.23 no.2
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• pp.214-220
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• 2019

The calibration method of the initial value error obtained in the weight measurement through anchor bolt type strain gauge sensor is proposed. The strain gauge sensor is developed for preventing the overturning of forklift, which is the most frequent type of safety-accident in industry. It was confirmed that the initial value error is caused from the physical and mechanical error of anchor bolt, and the environmental problem. Since the elimination of these causes falls outside the realm of this research, we find out the calibrated values based on all the causes, and we adjust the initial values of analog-to-digital convertor (ADC) module consisted of strain gauge sensor block using the calibrated values. We use the linear interpolation method for our calibration. We confirm that four sensor modules have the different under 5% between the real weight and the measured value in the experiment applied with the calibration of initial values. The low correlation between the real weights and ADC values is also improved through the proposed calibration.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.440-443
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• 2011

This paper aims to compose a new LED lighting control board in the LED lighting environment This LED lighting control board is designed to adjust the brightness of LED lighting depending on the change of surrounding brightness, and it is also designed to control the brightness by using ATmega128, which is an 8bit micro-controller, The PWM wave form likely to output into the LED driver is determined by the ADC value input through ADC.