• Journal of Nutrition and Health
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• v.54 no.5
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• pp.501-514
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• 2021

Purpose: The purpose of this study was to provide basic data for the management of atopic dermatitis (AD) in adults by analyzing the relationship between AD and intake of soft drinks in adults. Methods: This study was conducted on 5,931 adults aged 19 to 64 who completed the food frequency questionnaire (FFQ) for participants in the Korea National Health and Nutrition Examination Survey VII-3 and VII-1. Subjects were divided into an AD-diagnosed group and a non-AD group according to the diagnosis of AD. In addition, the group diagnosed with AD was divided into a 'symptom-AD' group and a 'no symptom-AD' group. The amount, frequency of intake, and nutritional status of soft drinks were analyzed using the FFQ. Results: Compared with the nutrient intake per 1,000 kcal of energy consumption, fat intake was higher in the AD-diagnosed group than in the non-AD group, and carbohydrate, dietary fiber, calcium, phosphorus, iron, potassium, vitamin A, thiamin, and vitamin C were lower in AD-diagnosed group. The daily intake of soft drinks and the percentage of 'more than 0.5 servings per day' were also higher in the AD-diagnosed group than in the non-AD group. Also, the frequency of the intake of soft drinks was significantly higher in the AD-diagnosed group than in the non-AD group. The odds ratio of AD symptoms due to the intake of soft drinks increased 2.6 times when the intake was 'less than 0.5 serving per day'. Conclusion: AD in adults appears to be related to malnutrition and excessive consumption of soft drinks, and the current prevalence of AD symptoms may also be related to the intake of soft drinks. Based on these results, we suggest that one of the ways to manage AD in adults would be to limit their intake of soft drinks.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.04a
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• pp.1314-1316
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• 2009

최근 모바일 단말의 사용과 그에 관련된 제품의 개발이 급증하고 있는 관계로 이와 관련된 많은 Peer-to-Peer (P2P) 연구들이 진행 중이다. 특히, Mobile Ad-Hoc 네트워킹 환경에서의 P2P 방식에 대한 연구 또한 활발히 진행되고 있다. 하지만, Flooding 방식의 메시지 전송은, 파일 탐색 시 Query 메시지 가 기하급수 적으로 증가할 수 있다. 이러한 메시지 전송은 센서 네트워크에서는 전력의 급격한 소모를 가져와 네트워크의 유지를 할 수 없게 하는 등의 오버헤드를 발생시킨다. 본 논문에서는 이러한 P2P 파일 검색에서의 메시지 전송수를 줄이기 위해 Mobile Ad-Hoc Network 환경에서 Peer를 Parent Peer(PPR)와 Child Peer(CPR)로 구분화하여 그룹화를 시키고 그룹을 Peer로 둔 P2P 네트워크를 구성하였다. 또한, 그룹 안에서 발생하는 CPR들의 가입과 탈퇴를 관리하여 오버헤드 발생을 줄이는 방법을 제안한다.

• The Journal of Pediatrics of Korean Medicine
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• v.32 no.3
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• pp.90-99
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• 2018

Objectives Hwangnyeonhaedok-tang is a Korean herbal medical treatment that removes toxic heat, fever and inflammation. The purpose of this study was to investigate the effect of Hwangnyeonhaedok-tang treatment on the relief of atopic dermatitis (AD) through regeneration of skin lipid barrier. Methods Male NC/Nga mice (20 g, 6 week age) were used. Each 10 mice were allocated to the control group (Ctrl), the AD-induced with no treatment group (AE), and the group which induced AD after administering Hwangnyeonhaedok-tang extract (HT). To induce AD-like skin lesions, sodium dodecyl sulfate (SDS) (Sigma-Aldrich, USA) was rubbed on the back of each mouse to remove the lipid lamella of the stratum corneum, and Dermatophagoides (D.) farinae crude extract was applied. HT group was orally administered Hwangnyeonhaedok-tang after induction of AD. IL-4 IL-13, $p-I{\kappa}B$, iNOS, Sudan Black B (SB), loricrin, and filaggrin were observed to confirm the effect. Results In HT group, AD skin score was decreased by 46%. The cytokine IL-4 and IL-13, which can identify Th2 differentiation, was reduced by 73% and 58% each. Anti-inflammatory effects were observed in $p-I{\kappa}B$ and iNOS by 69% and 54%, respectively. Finally, SB showed that the regeneration of the lipid layer and the increase of the regeneration power of loricrin and filaggrin were increased by 437% and 464%, respectively. Conclusions From the study result, we observed that Hwangnyeonhaedok-tang treatment alleviates AD by decreasing skin score, reducing Th2 differentiation, inducing anti-inflammatory, and increasing skin lipid barrier regeneration. Thus, Hwangnyeonhaedok-tang treatment would be considered as an effective AD relieving treatment.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.5A
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• pp.526-535
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• 2008

Recently, several MAC protocols using the directional antennas have been proposed for wireless mobile ad hoc networks. In the theory, it can improve spatial reuse and communication throughput in the Mobile Ad-hoc networks. But, or However even though direction transmissions using the Directional MAC protocol(D-MAC) are expected to provide significant improvements, they causes other problems such as deafness problem and fairness problem. In this paper, we analyze the D-MAC protocol in Mobile Ad-hoc network for Vehicle to vehicle(V2V) communication. Through the results of the analysis, We the fundamental problem of D-MAC protocol and finally we suggest new D-MAC protocol for V2V networks.

• BMB Reports
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• v.56 no.9
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• pp.520-525
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• 2023

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by cognitive decline. Several recent studies demonstrated that impaired adult neurogenesis could contribute to AD-related cognitive impairment. Adult subventricular zone (SVZ) neurogenesis, which occurs in the lateral ventricles, plays a crucial role in structural plasticity and neural circuit maintenance. Alterations in adult SVZ neurogenesis are early events in AD, and impaired adult neurogenesis is influenced by the accumulation of intracellular Aβ. Although Aβ-overexpressing transgenic 5XFAD mice are an AD animal model well representative of Aβ-related pathologies in the brain, the characterization of altered adult SVZ neurogenesis following AD progression in 5XFAD mice has not been thoroughly examined. Therefore, we validated the characterization of adult SVZ neurogenesis changes with AD progression in 2-, 4-, 8-, and 11-monthold male 5XFAD mice. We first investigated the Aβ accumulation in the SVZ using the 4G8 antibody. We observed intracellular Aβ accumulation in the SVZ of 2-month-old 5XFAD mice. In addition, 5XFAD mice exhibited significantly increased Aβ deposition in the SVZ with age. Next, we performed a histological analysis to investigate changes in various phases of adult neurogenesis, such as quiescence, proliferation, and differentiation, in SVZ. Compared to age-matched wild-type (WT) mice, quiescent neural stem cells were reduced in 5XFAD mice from 2-11 months of age. Moreover, proliferative neural stem cells were decreased in 5XFAD mice from 2 to 8 months of age. Furthermore, differentiations of neuroblasts were diminished in 5XFAD mice from 2-11 months of age. Intriguingly, we found that adult SVZ neurogenesis was reduced with aging in healthy mice. Taken together, our results revealed that impairment of adult SVZ neurogenesis appears with aging or AD progression.

• ALGAE
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• v.37 no.4
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• pp.331-347
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• 2022

Atopic dermatitis (AD) is one of major skin inflammatory diseases characterized by excessive Th2-mediated immune responses. Recent evidence provides that interlukin-13 (IL-13) plays the role of a key Th2 cytokine that drives the inflammation underlining AD. Due to adverse effects of commercially available synthetic drugs, the need for treatments based on natural products is gaining much attention. Sargassum horneri is an edible brown algae known for beneficial bioactivities including anti-inflammation. We investigated if polyphenol-rich S. horneri extracts (SHE) could suppress AD-like skin lesions in NC/Nga mice and if that involved inhibition of the infiltration of Th2-mediated cytokine IL-13. We observed markedly increased infiltration of IL-13 positive cells in AD-like skin lesions of mice but SHE treatments decreased it. Also, the dermal expression of IL-13 was sufficient to cause inflammatory responses in mice skin resembling human AD. SHE suppressed the dermal infiltration of inflammatory cells where IL-13 plays a crucial role in skin tissues and in the recruitment of inflammatory cells. Furthermore, it was confirmed that SHE reduced T cell, dendritic cell, and macrophage populations in spleen. Moreover, SHE decreased the collagen deposition in skin and ear dermis resulting in reduced fibrosis that occurs in AD due to excessive collagen. Taken together, our results reveal that SHE suppressed the infiltration of inflammatory cells into skin dermis by decreasing the infiltration of IL-13 positive cells. Therefore, SHE could be taken as a useful therapeutic agent to alleviate AD.

• Journal of Hospice and Palliative Care
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• v.17 no.2
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• pp.66-74
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• 2014

Purpose: This study is aimed to investigate perceptions of caregivers and medical staff toward do not resuscitate (DNR) and advance directives (AD). Methods: Participants were 141 caregivers and 272 medical staff members from five general hospitals. A questionnaire used for the study consisted of 20 items: 14 about DNR perceptions, three about AD, one each for age, gender and employment. Results: Both medical staff and caregivers strongly recognized the need for DNR and AD, and the level of recognition was higher with medical staff than caregivers (DNR ${\chi}^2=44.56$, P=0.001; AD ${\chi}^2=16.23$, P=0.001). The main reason for the recognition was to alleviate sufferings of patients in the terminal phase. In most cases, DNR and AD were filled out when patients with terminal conditions were admitted, and patients made the decisions by consulting with their guardians. Medical staff better recognized the need and for growing demand for guidelines for the DNR and AD decision making process than caregivers (${\chi}^2=7.41$, P=0.0025). Conclusion: This study showed that patients highly rely on their caregivers when making decisions for DNR and AD. Thus, it is important that patients and caregivers are provided with objective information about the decisions. Since participants' strong support for DNR and AD was mainly aimed at alleviating patients' suffering, further study is needed in the association with hospice care. Medical staff also needs to understand the different views held by caregivers and fully consider the disparity when informing patients/caregivers to make the DNR and AD decisions.

• Journal of Fashion Business
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• v.12 no.3
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• pp.136-152
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• 2008

The purpose of this study was to provide dress forms and jacket blocks for adult males based on the analysis of their somatotypes. As the result of the research conducted for this study that was based on 1290 males of 20 to 54 years-old, the shapes of adult male were 20 and each body shape was classified by size factor, height and chest girth. Also, master sizes were selected considering appearance frequency. XS type (master size: height 165cm and chest circumference 88cm), Yd type (master size: height 170cm and chest circumference 91cm), YI and AD2 types (master size: height 170cm and chest circumference 94cm) were selected to develop dress forms and their jacket blocks in this study. The procedure and results were follows; 1. The dress forms of XS, Yd, YI and AD2 types were produced base on means of 61 body measurements and cross sections of shoulder, chest, waist, hip of subjects belong to each somatotype. 2. New jacket blocks for XS, Yd, YI and AD2 types were developed based on the body surface developments through draping and the results of comparative investigation on the existing jacket blocks by wearing test. Also the drafting methods of new jacket blocks were provided. 3. The sensory evaluation by wearing test showed that the developed jacket blocks were estimated more highly in terms of chest's allowance, the front width's allowance, neck wrinkle, front allowance and overall appearance's fitness items than existing jacket blocks.

• IEMEK Journal of Embedded Systems and Applications
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• v.2 no.3
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• pp.155-163
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• 2007

In Ad Hoc Networks, a connection breaks due to the irregular movement of mobile nodes and the inherent characteristics of the wireless medium such as the interference and the multi-path fading. AODV, a typical on-demand routing protocol in Ad Hoc networks, uses Destination sequence numbering for loop-free, but it may cause RREQ broadcast storm problem. This paper proposes AODV_ods that does not need destination sequence number, in routing message and routing table without routing loop. To show the effectiveness of the proposed scheme, we performed extensive simulation with NS-2. The simulation results show that the proposed ADOV_ods efficiently uses wireless bandwidth compare to the original AODV. Finally AODV ods reduces the routing overhead, end to end delay and increases the overall packet delivery ratio.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2002.05a
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• pp.117-120
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• 2002

Bluetooth uses baseband of 2.4G ISM and composes radio Ad Hoc network based on Ad Hoc wireless connectivity which it used low power and low complexity solution. Bluetooth designed as can play detect, connect, discover service by surrounding other device even if users do not get acquainted all to Bluetooth. This paper operate wish to recognize mobility to routing algorithm how communication method and radio network in Bluetooth.