• Proceedings of the Korea Society for Industrial Systems Conference
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• 2007.02a
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• pp.26-31
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• 2007

An ad hoc network is a collection of mobile nodes without any Infrastructure. However, ad hoc networks are vulnerable to attacks such as routing disruption and resource consumption; thus, routing protocol security is needed This paper proposes a secure and efficient routing protocol for mobile ad hoc networks, where only one-way hash function are used to authenticate nodes in the ROUTE REQUEST, while additional public-key cryptography is used to guard against active attackers disguising a node in the ROUTE REPLY.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04a
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• pp.652-654
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• 2004

Ad Hoc On-Demand Routing Protocol(AODV)이 ad hoc 네트워크에 알맞게 잘 설계되었지만, 인터넷과의 통신에는 그렇지 못하다. 인터넷과 ad hoc 네트워크의 통합에 몇 가지 해결책이 제안되었다. 그러나 그 제안들은 몇 가지 결점을 가지고 있다. 그에 따라 우리는 중복 제어 패킷을 처리하는 동안의 제어패킷 오버헤드와 전원 소모를 줄인 동적 에이전트 광고를 제안하였으며 패킷 전송에 대한 오버헤드를 기존의 해결책과 비교하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10a
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• pp.616-618
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• 2003

최근 급속하게 성장하고 있는 무선 이동 통신 분야중의 한 분야가 Ad hoc 네트워크 분야일 것이다. Ad hoc 네트워크는 기존의 고정된 네트워크의 한계를 뛰어 넘는 네트워크이다. 본 연구에서는 Ad hoc 네트워크의 클러스터 기반의 라우팅 프로토콜에서의 인증에 대한 프로토콜을 멀티 계층으로 설계하였다. CBRP(Cluster Based Routing Protocol)의 라우팅 프로토콜에서는 클러스터간의 인증을 위하여 CH(Cluster Head)간의 인증을 통하여 인증을 하게 된다. CH간의 신뢰성을 위하여 MCH(Main Cluster Head)를 두어 CH간의 신뢰성을 보장함으로써 상호 클러스터간의 인증을 위한 프로토콜을 설계하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2005.07a
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• pp.541-543
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• 2005

본 논문에서는 Ad Hoc 네트워크와 Ad Hoc 라우팅 프로토콜 중에 대표적인 On-demand 방식인 AODV(Ad Hoc On-demand Distance Vector) 라우팅 프로토콜에 대해 알아본다. 본 연구의 목표는 멀티미디어 데이터를 위한 QoS를 지원하는 새로운 라우팅 알고리즘을 제안하고, 네트워크 시뮬레이터에 구현하여 다양한 실험환경에서 제안한 라우팅 알고리즘에 대한 성능평가를 수행하는 것이다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10a
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• pp.631-633
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• 2004

본 논문은 유비쿼터스 환경에서 리소스가 제한적인 이동통신 단말기 등에서 하위 네트워크 프로토콜이나 전송방식에 독립적인 서비스 발견을 위한 프레임웍을 설계하는데 있다. 이 연구의 접근은 Jini라는 서비스 프레임웍을 모바일 디바이스에 맞게 경량화하고 이 프레임웍에 다양한 Ad-hoc 전송 계층을 추가할 수 있도록 확장 가능한 Jini 서비스 프레임웍 제공함으로써 기존에 서비스가 가지던 네트워크 전송계층의 의존성을 극복하고자 하였다. 이를 위해 본 논문에서는 Bluetooth 전송기술을 하나의 Ad-hoc 네트워크 모델로 삼아 Jini 프레임웍 내에서 STL(Service Translation Layer)를 추가함으로써 Jini를 통한 Ad-hoc 네트워크에서 서비스 발견을 가능토록 하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10a
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• pp.436-438
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• 2004

이동 ad-hoc 네트워크(mobile ad-hoc network : MANET)는 유선 기반 망 흑은 액세스 포인트 없이 이동 단말기들로 구성된 망이다. 기존의 기반망을 사용하지 않으므로 유선 기반망이 구축되어 있지 않은 곳이나 유선 기반망이 파괴된 지역에 사용한다. 그러나 HANET에서는 노출된 매체와 동적인 토폴로지, 중앙의 감시와 관리 결여, 자원의 제약성 등과 같은 이유로 인해 유선망보다 더욱 않은 보안 문제가 발생한다. 본 논문에서는 이동 ad hoc 네트워크에서 노드의 신분 보장을 제공하기 위하여 기밀성에 중점을 둔 공개키 기반 구조에서의 노드 간 인증 기법을 제안한다.

• Tuberculosis and Respiratory Diseases
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• v.51 no.2
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• pp.135-146
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• 2001

Background : One of the important mechanisms responsible for a tumor escaping the immune response is an absence of the tumor associated antigen (TAA) on the cancer cell surface. To overcome this, combination gene therapy using a herpes simplex thymidine kinase (HSTK) gene, prototype of drug sensitizing gene, was conducted to enhance T AA release by cell destruction, as well as the cytokine genes for immune cell attraction. Methods : We investigated whether or not transduction with the adenovirus-HSTK (Ad-HSTK) enhanced the sensitivity of Lewis lung carcinoma (LLC) to ganciclovir (GCV) and induced a bystander effect. A Tumor vaccine trial was performed using LLC with ad-HSTK$\pm$ad-GM-CSF$\pm$ad-IL-2 to determine if they exhibit some antitumor effect on established lung cancer xenografts. Results : LLC with ad-HSTK revealed a much higher sensitivity to ganciclovir (GCV). LLC transduced with ad-HSTK and/or ad-IL-2, ad-GM-CSF showed a lower in vivo tumorigenicity. In the treatment experiment, vaccination with LLC transduced with ad-HSTK, ad-IL-2, or ad-GM-CSF alone modestly suppressed the growth of an established tumor. Combined transduction with HSTK and GM-CSF induced stronger growth suppression of a established lung cancer, while HSTK and IL-2 combination transduction did not have any antitumor effect on individual transduction. Vaccination with LLC-HSTK-GM-CSF increased the infiltration of dendritic cells in the spleen. Conclusion : It was concluded that a tumor vaccine transduced with HSTK and GM-CSF induces strong antitumor immunity by activating the dendritic cells.

• Journal of Korea Society of Industrial Information Systems
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• v.10 no.3
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• pp.30-37
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• 2005

Ad hoc network is a collection of mobile nodes without using any infrastructure, it , is using in the various fields. Because ad hoc network is vulnerable to attacks such as routing disruption and resource consumption, it is in need of routing protocol security. In this paper, we propose two secure route-discovery protocols. One is a protocol using hash function. This protocol is weak in active attack but has some merits such as small data of transmission packet and small computation at each hop. The other is a protocol using hash function and public key cryptography. This protocol is strong in active attack.

• Asian Journal of Atmospheric Environment
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• v.10 no.2
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• pp.114-123
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• 2016

A change in chemical compositions of Asian dust (AD) particles can dramatically alter their optical properties, cloud-forming properties, and health effects. The present study was undertaken to evaluate this aging of AD particles by means of two complementary methods (i.e., the traditional spot test and the most advanced micro-PIXE analytical technique) for single particle analysis. Size-classified particles were sampled at the rural peninsula of Korea (Byunsan, 35.37N; 126.27E) during AD event and non-AD period in 2004. Sulfate was principally enriched on the particles in the size range of $7.65-10.85{\mu}m$ collected during AD event. The average number fraction of coarse particles ($>2.05{\mu}m$) containing chloride was 16.2% during AD event. Relatively low particles containing nitrate compared to those containing sulfate and chloride were found in AD event. Micro-PIXE elemental maps indicated that a large number of AD particles were internally mixed with man-made zinc. The highest peaks of EC and OC concentrations were appeared at $0.01-0.43{\mu}m$ particle aerodynamic diameter. High EC concentration in $PM_1$ was might be caused by the Saemangeum Seawall Project that was being conducted during our field measurement.

• Herbal Formula Science
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• v.11 no.2
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• pp.95-110
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• 2003

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the near future AD will be the biggest problem in public health service. Although a variety of oriental prescriptions in study Jeonmaedan have been traditionally utilized for the treatment of AD, their pharmacological effects and action mechanisms have not yet fully elucidated. It has been widely believed that A${\beta}$ peptide devided from APP causes apoptotic neurotoxicity in AD brain. However, recent evidence suggests that CTl05(carboxy terminal 105 amino acid peptide fragment of APP) may be an important factor causing neurotoxicity in AD. In addition, AD is one of brain degeneration disease. So we studied on herbal medicine that have a relation of brain degeneration. In Oriental Medicine, Jeonmaedan has been used for disease in relation to brain degeneration. As the result of this study, in Jeonmaedan the apoptosis in the nervous system is inhibited, the repair against the degerneration of SK-N-SH cell lines by CT105 expression is promoted. So Jeonmaedan may be beneficial for the treatment of AD.