• The Transactions of the Korea Information Processing Society
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• v.5 no.4
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• pp.975-983
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• 1998

In these days, information communication systems are based on both open distributed computing technologies and object-oriented techniques like inheritance, encapsulation and object reuse to support various system configuration and application. As information systems are interconnected through unsecure networks, the need for the secure information exchange is more critical than before. In this paper, we have designed and implemented a transparent CORBA-basce Security infrastructure with authentication, security context association, access control and security information management to support a secure applications in distributed object environment. SESAME Ver. 4 was adopted as an external security service to manage user privilege attributes and to distribute keys for data encryption, decryption and integrity. Using filter and transformer with an interface to Object Request Broker, it provides a transparent security service to applications. The filter objects are special classes that allow additional parameters to be inserted into messages before they are sent and removed just after they are received. The transformer objects are special classes that allow direct access to the byte stream of every messages for encryption and decryption before it is sent and just after it is received. This study is to implement the access control interceptor(ACI) and the secure invocation interceptor(SII) of secure ORB defined in CORBA using filter and transformer.

• The Journal of Korean Medicine
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• v.34 no.3
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• pp.54-68
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• 2013

Objectives: This study aimed to evaluate the effects of microparticles of Socheongryong-tang (SCRT) on chronic obstructive pulmonary disease (COPD) in a mouse model. Methods: The inhalable microparticles containing SCRT were produced by spray-drying with leucine as an excipient, and evaluated with respect to the aerodynamic properties of the powder by Andersen cascade impactor (ACI). Its equivalence to SCRT extract was evaluated using lipopolysaccharide (LPS) and a cigarette-smoking (CS)-induced murine COPD model. Results: SCRT microparticles provided desirable aerodynamic properties (fine particle fraction of $49.6{\pm}5.5%$ and mass median aerodynamic diameter of $4.8{\pm}0.3{\mu}m$). SCRT microparticles did not show mortality or clinical signs over 14 days. Also there were no significant differences in body weight, organ weights or serum chemical parameters between SCRT microparticle-treated and non-treated groups. After 14 days the platelet count significantly increased compared with the non-treated group, but the values were within the normal range. Inhalation of SCRT microparticles decreased the rate of neutrophils in blood, granulocytes in peripheral blood mononuclear cells (PBMC) and bronchoalveolar lavage fluid (BALF) and level of TNF-${\alpha}$ and IL-6 in BALF on COPD mouse model induced by LPS plus CS. This effect was verified by histological findings including immunofluorescence staining of elastin, collagen, and caspase 3 protein in lung tissue. Conclusions: These data demonstrate that SCRT microparticles are equivalent to SCRT extract in pharmaceutical properties for COPD. This study suggests that SCRT microparticles would be a potential agent of inhalation therapy for the treatment of COPD.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.7
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• pp.120-128
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• 2019

It is very important to verify the seismic performance and stability of the power plant fixture in the domestic power plant, because earthquakes have increased in frequency around the world which resulted in the frequent occurrence of power plant damage caused by the failure of electric power facilities. In this study, through the on-site inspection of power plant fixation unit installed in domestic power plants, we carried out structural performance evaluation of the fixation unit anchor bolts installed on the concrete slabs. The field survey showed M12 J hook anchor bolts were used. Anchor bolt pullout and shear performance evaluation were performed based on ASTM E 488-96 standard. Moreover, artificial crack with the width of 0.5 mm was applied during the experiment based on ATM355.4 and ETAG 001. The comparison of M12 J hook anchor bolt pullout and shear test result to design value required in domestic and international design standard, show a satisfactory result. M12 J hook anchor pullout and shear performance was found to be about 35% and 7%, respectively, higher than the required design value.

• Magazine of the Korea Concrete Institute
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• v.11 no.2
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• pp.187-196
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• 1999

An experimental investigation was conducted to study the structural behavior of concrete columns confined with welded grids. The full-scale columns with different volumetric ratio, spacing and arrangement of welded reinforcement grids were tested under simulated seismic loading. The columns were subjected to constant axial compression of approximately 20% or 40% of their capacities accompanied by incrementally increasing lateral deformation reversals. The results indicate that the welded reinforcement grid can be used effectively as confinement reinforcement provided that the steel used, have sufficient ductility and the welding process employed does not alter the strength and elongation characteristics of steel. The grids improved the structural performance of columns, which developed lateral drift ratios in excess of 3% with the spacing and volumetric ratio of transverse reinforcement similar to those required by the ACI 318-95 Building Code. Drift capacity further increased when grids with larger number of cells were used. Furthermore, the use of grids reduced congesting of reinforcement while the dimensional accuracy provided perfect support to longitudinal reinforcement.

• Journal of the Korea Concrete Institute
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• v.17 no.1 s.85
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• pp.85-94
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• 2005

Post-tensioned Precast concrete System(PPS) consists of U-shaped precast wide beams and concrete column. The continuity of beam-column joint is provided with floor concrete cast on the PC shell beam and post-tensioning. The purpose of this paper is to evaluate the response of PPS interior beam-column joint subjected to cyclic lateral loading. To this end, an experimental investigation was performed with three half-scale specimens of interior connection. The design parameters are the amount of beam reinforcement placed inside the joint core. The test results showed that cracks were distributed well without my significant degradation of strength and ductility. Also, it was found that the prestressing may affect to alter the torsional crack angle. And the specimens sufficiently resist up to limiting drift ratio of 0.035 in accordance with the provisional by ACl of acceptance criteria for concrete special moment frames.

• Magazine of the Korea Concrete Institute
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• v.3 no.2
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• pp.123-132
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• 1991

The purpose of this study was to Investigate the effects of bent - up bar Within beam - column 1lint core with High - Strength Concrete up to 800kg/$cm^2$. To achieve these objectives, 5 specimens were designed and tested under monotoric loading and reversed cyclic loadings. The primary variables were the number of bent-up bars, compressive strength of concrete and loading patterns. The results showed that the load capacity of specimen subjected to monotonic loading had more large than that of specirnn subjected to reversed cyclic loadings and the bent - up bar within joint core could prevented the crack at the joint face from propagating into the pint core but the failure was concentrated at the face of beam - column pint. Thus the study on flexural strength ratio should be accomplished before using bent - up bars within the joint core.

• Journal of Chest Surgery
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• v.29 no.7
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• pp.713-722
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• 1996

Poor long term patient survival (60% at 2 years) in lung allograft recipients are mainly due to rejection and complications associated with the use of nonspecific immunosuppressants. Better means to achieve waft acceptance is desperately needed. 1 have investigated whether mixed allogeneic chimerism in the form of bone marrow stem cell engraftment would induce donor-specific tolerance for lung allografts. Fisher (F344) and Wistar Forth (WF)rats were lethally irradiated (1100c0y) and reconstituted with a mixture of T-cell depleted syngeneic and allogeneic bone marrow (F344+WFIWF, ACI +F344- F344). After Mixed chimerism was documented by peripheral blood Ipnphocyte typing at 28 days, orthotopic left single lung transplantation was performed, using donor-s ecific or third party allografts. No immunosuppressants were administered. Graft rejection was monitored by chest rentgenography, and con- firmed by histology Mixed chimeric rats accepted lung allografts permanently, and it was not strain specific effect. Tolerance was all or none phenomenon which had nothing to do with the percentage of chimerlsm. Mixed chimeras rejected third party allografts in less than 10 days, a time course similar to that of unmanipulated controls. No acute or chronic rejection was observed in donor specific grafts more than 150 days posttransplant. These data suggest that mixed chimerism in the form of bone marrow stem cell engraftment results in stable, systemic donor-specific transplantation tolerance for lung allografts.

• Journal of Animal Science and Technology
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• v.44 no.1
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• pp.23-30
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• 2002

PCR-RFLP analysis was carried out to investigate the genotype of Melanocortin receptor 1 (MC1R) gene in Korean Brindle Cattle and Korean Cattle with dark muzzle, which are coat color and muzzle pigmentation variants of Korean Cattle, respectively. Allelic variants of MC1R in cattle were analyzed by digestion with BsrFⅠ, AciⅠ. Among six genotypes, $E^D/E^D,\;E^D/E^+,\;E^D/e,\;E^+/E^+,\;E^+$/e and e/e, detected in cattle, only two genotypes, $E^+/E^+\;and\;E^+$/e, were observed in Korean Brindle Cattle, probably reflecting the necessary of $E^+$ allele for the expression of black brindle coat color. As in Korean Cattle with light muzzle, the $E^+$/e and e/e genotypes were detected in Korean Cattle with dark muzzle. The $E^+$ and e alleles frequencies in two populations of Korean Cattle with dark muzzle and with light muzzle were 0.37, 0.63 and 0,11, 0.89, respectively. Although the frequency of $E^+$ allele in Korean Cattle with dark muzzle was higher than in Korean Cattle with light muzzle, the $E^+$ allele was not completely associated with dark muzzle pigmentation. The results of this experiment indicate that the difference of MC1R genotype and frequency may be useful for fixation of coat color in Korean Cattle as well as Korean Brindle Cattle.

• Journal of the Korean Society for Advanced Composite Structures
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• v.6 no.2
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• pp.105-117
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• 2015

The purpose of this study is to develop a new seismic resistant method by using precast concrete wall panels for existing low-rise, reinforced concrete beam-column buildings such as school buildings. Three quasi-static hysteresis loading tests were experimentally performed on one unreinforced beam-column specimen and two reinforced specimens with L-type precast wall panels. The results were analyzed to find that the specimen with anchored connection experienced shear failure, while the other specimen with steel plate connection principally manifested flexural failure. The ultimate strength of the specimens was determined to be the weaker of the shear strength of top connection and flexural strength at the critical section of precast panel. In this setup of L-type panel specimens, if a push loading is applied to the reinforced concrete column on one side and push the precast concrete panel, a pull loading from upper shear connection is to be applied to the other side of the top shear connection of precast panel. Since the composite flexural behavior of the two members govern the total behavior during the push loading process, the ultimate horizontal resistance of this specimen was not directly influenced by shear strength at the top connection of precast panel. However, the RC column and PC wall panel member mainly exhibited non-composite behavior during the pull loading process. The ultimate horizontal resistance was directly influenced by the shear strength of top connection because the pull loading from the beam applied directly to the upper shear connection. The analytical result for the internal shear resistance at the connection pursuant to the anchor shear design of ACI 318M-11 Appendix-D except for the equation to predict the concrete breakout failure strength at the concrete side, principally agreed with the experimental result based on the elastic analysis of Midas-Zen by using the largest loading from experiment.

• Journal of the Korea Concrete Institute
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• v.18 no.5 s.95
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• pp.621-630
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• 2006

Twelve beams made of lightweight high-strength concrete were tested to determine their diagonal cracking and ultimate shear capacities. A total of 12 beams without(4 beams) and with lightweight(8 beams) were tested in a stiff testing facility, and complete load-midspan deflection curves, including the maximum capacities portion, were obtained. The variables in the test program were concrete strength, which varied 35.4 MPa, 65.3 MPa; shear span-depth ratios a/d=1.5, 2.5, 3.5, 4.5; and tensile steel ratio between 0.57 and 2.3 percent. Also, we divided beam by diagonal tension crack and ultimate shearing strength to propose an equation. In addition, it analyzed comparison mutually applying existing proposal and guide. $V_{cr}$ was as result that AIK recommendations and Zsutty proposal decrease more than a/d=2.5, increased some in Mathey's proposal equation. $V_{cr,\exp}/V_{cr,cal}$ showed tendency of overestimation according to increase of tensile steel ratio and compressive strength of concrete. On the other hand, $V_{cr,\exp}/V_{cr,cal}$ is superior in conformability with an experiment result Zsutty's proposal among other equations. The proposal equation hew that expect $V_{cr}/V_u$, rationally about shearing strength. Therefore, shear strength an equation is considered to be utilized usefully evaluating capacity by change of the shear span depth ratio of lightweight concrete, tensile steel ratio, and compressive strength of the concrete in this research.