• Nuclear Medicine and Molecular Imaging
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• v.43 no.1
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• pp.35-39
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• 2009

Purpose: Increased FDG uptake in the bone marrow has been reported in patients taking erythropoietin or granulocyte-colony stimulating factor (G-CSF). The aim of this study is to investigate the correlation between F-18 FDG uptake in the bone marrow and bone marrow finding, hematological parameters. Materials and Methods: Twenty patients who had diffuse FOG uptake at the bone marrow and received hematological examinations, bone marrow biopsy within 10 days before or after PET/CT were enrolled in this study. Among them, 11 patients were excluded; 4 patients received G-CSF or erythropoietin before PET/CT. Seven patients showed definite pathology in a bone marrow biopsy. The parameters included the measurement of WBC, hemoglobin, platelet and cellularity of the bone marrow. Results: Bone marrow FDG uptake was correlated with a low hemoglobin but not WBC, platelet. Histopathologic findings in marrow biopsies were various: normal finding (n=3), hyperplasia of granulocytic cells (n=2), eosinophilic hyperplasia (n=1), reactive lymphoid nodules (n=1), hypercelluar marrow (n=1), hypocelluar marrow (n=1). All patients except two, showed normal marrow celluarity. Conclusion: FOG uptake by bone marrow correlated with anemia but not WBC, platelet, bone marrow cellularity.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.2 no.2
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• pp.92-100
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• 1997

Distribution of bacterial abundance and production was investigated during October, 1995-August, 1996 in Lake Shiwha constructed artificially in 1994. Its water column was distinguished by two layers: the brackish surface layer with salinity ranged from 6 to 20‰ and the saline hypoxic/anoxic bottom layer with salinity of 17 to 27‰ Except for samples collected in March, 1996 (on average 13 ${\mu}g\;l^{-1}$), chlorophyll a concentration ranged from 27.6 to 249.5 ${\mu}g\;l^{-1}$ in the euphotic zone, indicating the hypertrophic condition of Lake Shiwha during most of the studied period. In this study, bacterial productions measured by $^3H$-thymidine incorporation method were similar to those by $^{14}C$-leucine incorporation method. In hypertrophic, surface waters of Lake Shiwha, bacterial abundance and production ranged from 1.4 to $19.5{\times}10^9\;cells\;l^{-1}$ and from 1.6 to $126.5{\times}10^7\;cells\;l^{-1}\;h^{-1}$ respectively; 2 to 4 fold and 2 to 30 fold higher than those in eutrophic coastal waters outside of Lake Shiwha, respectively. Turnover times of bacterial community in the surface layer of Lake Shiwha ranged from 0.2 to 8.9 day, indicating that bacteria in the lake seemed to adapt to the hypertrophic condition. In the hypoxic bottom layer, bacterial abundance and production was up to 3 fold and 20 fold lower than those in the surface layer, and showed slow bacterial growth. Significant correlations between the bacterial abundance, production, and community turnover time with water temperature indicate water temperature was the important factor controlling distribution and growth of bacteria. However, during summer season, bacterial production seemed to be regulated by supply of substrates.

• The Korean Journal of Food And Nutrition
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• v.29 no.1
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• pp.65-72
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• 2016

Black tomato (Lycopersicum esculentum) is known to have more ${\beta}-carotene$, lycopene, and vitamin C than general red-colored tomatoes. In this study, we evaluated the quality properties, antioxidant activities and sensory characteristics of black tomato cookies. Cookies were prepared by replacing 0, 1, 3, 5, and 7% of flour with black tomato powder. Density of black tomato cookies tended to be decreased between control (1.20) and 3% added groups (1.12). pH value was decreased from control (6.66) to 7% added group (5.16). Spread factor and loss rate were increased with increasing amounts of black tomato powder. Hardness was gradually increased from $107.77g/cm^2$ in control to $170.50g/cm^2$ in 7% added group. Color measurement indicated that L-value (brightness) was highest in control (70.46) and lowest in 7% added group (45.23); whereas, a-value (redness) increased while b-value (yellowness) tended to decrease with increasing amounts of black tomato powder. Total polyphenol contents and DPPH radical scavenging activities were directly proportional to the amount of black tomato powder. Consumer preference scores in color and flavor of black tomato powder added group were higher than those of control. Characteristic strength test was not significantly different among the groups. Overall, the results indicated that adding 5% black tomato powder is desirable for making black tomato cookies.

• Korean journal of food and cookery science
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• v.27 no.3
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• pp.11-20
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• 2011

The purpose of this study was to investigate the use and perception of adults concerning bokbunja (Rubus coreanus Miquel) products. Self-administered questionnaires were collected from 502 residents in the Daegu and Gyeongbuk area. According to the survey more females in their 20s responded than males (45.2 and 54.8%, respectively). In total, 82.6% of respondents had an income of under 4,000,000 won per month and most were living in the city. The results regarding knowledge about bokbunja products showed that the bokbunja wine score was highest (3.66), and intake frequency showed that over half of the respondents had never eaten bokbunja products. The preference for bokbunja wine by males was higher than that for females, whereas the others products showed higher scores for females than for males. When asked about how they knew about bokbunja products, 37.0% of males and 46.9% of females responded a family member or neighbor. When purchasing bokbunja products, males and females answered that they considered taste, country of origin, and manufacturer, and price. Approximately 48% of the respondents answered that they purchased bokbunja products in the grocery and department store. As a result, popularization of bokbunja products was based on product development and sales promotion, and the product development factor significantly influenced preference for bokbunja products.

• Clinical and Experimental Reproductive Medicine
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• v.24 no.1
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• pp.83-93
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• 1997

Although IVF-ET is widely applied in the treatment of couples with male factor infertility, it may fail in many infertile couples with normal semen parameters, and certain couples cannot be accepted for standard IVF-ET due to unfertilization or extremely low fertilization rate of oocytes. Recently, several procedures of microassisted fertilization (MAF) using micromanipulation have been introduced, and pregnancies and births have been obtained after partial zona dissection (PZD), subzonal insertion (SUZI), and intracytoplasmic sperm injection (ICSI). This clinical study was performed to develop and establish ICSI as an effective procedure of MAF in infertile couples who could not undergo standard IVF-ET repetitively because of failure in fertilization or extremely low fertilization rate of oocytes with the conventional fertilization technique in the previous IVF-ET cycles. From March, 1995 to May, 1996, 27 cycles of IVF-ET with ICSI in 19 infertile patients were included in study group, and the outcomes of ICSI were analyzed according to fertilization rate, cumulative embryo score (CES), and pregnancy rate. The number of oocytes retrieved after controlled ovarian hyperstimulation (COH) was $10.50{\pm}6.13$ in 30 previous cycles, and $10.57{\pm}5.53$ in 27 ICSI cycles. In ICSI cycles, the number of oocytes optimal for ICSI procedure was $7.89{\pm}4.30$, and the fertilization rate of $67.9{\pm}20.2%$ could be obtained after ICSI. The number of embryos transferred was $1.43{\pm}2.40$ in previous cycles, and $4.36{\pm}1.77$ with the mean CES of $41.8{\pm}27.4$ in ICSI cycles. In ICSI cycles, the overall pregnancy rate was 29.6% (8/27) per cycle and 42.1% (8/19) per patient with the clinical pregnancy rate of 22.2% (6/27) per cycle and 31.6% (6/19) per patient. In conclusion, MAF of human oocytes with ICSI is a promising fertilization method for IVF-ET patients, especially with the past history of failure in fertilization or low fertilization rate of oocytes in the previous IVF-ET cycles, and ICSI using micromanipulation procedures applied to human oocytes will provide a range of novel techniques which may dramatically improve the pregnancy rate in IVF-ET program and contribute much to effective management of infertile couples.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.11
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• pp.102-111
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• 1999

In this paper, we propose a fast full search block matching algorithm using the search region subsampling and the difference of adjacent pixels in current block. In the proposed algorithm, we calculate the lower bound of mean absolute difference (MAD) at each search point using the MAD value of neighbor search point and the difference of adjacent pixels in current block. After that, we perform block matching process only at the search points that need block matching process using the lower bound of MAD at each search point. To calculate the lower bound of MAD at each search point, we need the MAD value of neighbor search point. Therefore, the search points are subsampled at the factor of 4 and the MAD value at the subsampled search points are calculated by the block matching process. And then, the lower bound of MAD at the rest search points are calculated using the MAD value of the neighbor subsampled search point and the difference of adjacent pixels in current block. Finally, we discard the search points that have the lower bound of MAD value exceed the reference MAD which is the minimum MAD value of the MAD values at the subsampled search points and we perform the block matching process only at the search points that need block matching process. By doing so, we can reduce the computation complexity drastically while the motion compensated error performance is kept the same as that of full search block matching algorithm (FSBMA). The experimental results show that the proposed method has a much lower computational complexity than that of FSBMA while the motion compensated error performance of the proposed method is kept same as that of FSBMA.

• Economic and Environmental Geology
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• v.38 no.5 s.174
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• pp.499-512
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• 2005

EPMA determined that Fe(Mn)-(oxy)hydroxides and well-crystallized Fe-(oxy)hydroxides and could contain a small amount of As $(0.3-11.0\;wt.\%\;and\;2.1-7.4\;wt.\%\;respectively)$. Amorphous crystalline Fe-(oxy) hydroxide assemblages were identified as the richest in As with $28-36\;wt.\%$. On the ternary $As_2O_5-SO_3-Fe_2O_3$ diagram, these materials were interpreted here as 'scorodite-like'. Dissolved As was attenuated by the adsorption on Fe-(oxy) hydroxides and Fe(Mn)-(oxy) hydroxides and/or the formation of an amorphous Fe-As phase (maybe scorodite: $FeAsO_4\cdot2H_2O$). Leaching tests were performed in order to find out leaching characteristics of As and Fe under acidic conditions. At the initial pHs 3 and 5, As contents dissolved from tailings of the cheongyang mine significantly increased after 7 days due to the oxidation of As-bearing secondary minerals (up to ca. $2.4\%$ of total), while As of Seobo mine-tailing samples was rarely released (ca. $0.0-0.1\%$ of total). Dissolution experiments at an initial pH 1 liberated a higher amount of As (ca. $1.1-4.2\%$ of total for Seobo tailings, $1.5-14.4\%$ of total for Cheongyang tailings). In addition, good correlation between As and Fe in leached solutions with tailings was observed. The kinetic problems could be the important factor which leads to increasing concentrations of As in the runoff water. Release of As from Cheongyang tailings can potentially pose adverse impact to surface and groundwater qualities in the surrounding environment, while precipitation of secondary minerals and the adsorption of As are efficient mechanisms for decreasing the mobilities of As in the surface environment of Seobo mine area.

• Journal of Hospice and Palliative Care
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• v.5 no.2
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• pp.146-154
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• 2002

Purpose : Death due to cancer has been continuously increasing, therefore cancer is the first in the cause of death now. A national policy for the elevation of medical costs in cancer patients is necessary, therefore, we searched for the medical costs and its related factors in terminal cancer patients for the effective reduction of the medical costs. Methods : We reviewed the medical records of 259 hospitalized terminal cancer patients who had died during the period of July 1, 2000 to June 30, 2002. History of cancer included type of cancer, type of past treatment, existence of metastasis. Clinical manifestation was examined and medical costs on last admission was categorized based on the account of charges of the department of patient affair on the last hospitalization. For analysis of factors related with medical costs, ANOVA was used. Results : Of the 259 patients, the number of male was 135 cases (52.1%), and the female, 124 cases (47.9%). The most frequent type of cancer was stomach (21.9%) cancer. Of the clinical manifestation, anorexia (87.6%) was the most frequent manifestation. Total medical costs was 740,628,045won, the mean costs was $285,968{\pm}3,070,272won$. The frequent category of medical costs was injection (32.0%), medical accommodation (27.9%), examination (14.0%), in order. The only factor related with mean medical costs was pain (P<0.05). Conclusion : If unnecessary injection of opioid analgesics is reduced, hospice care at home is activated and excessive examination is reduced In terminal cancer inpatients, it will be possible to reduce the medical costs in terminal cancer patients more effectively.

• Journal of Hospice and Palliative Care
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• v.18 no.2
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• pp.120-127
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• 2015

Purpose: We aimed to investigate how serum vitamin D levels are related to survival of terminally ill cancer patients. Methods: From May 2012 through June 2013, a retrospective chart review was performed on 96 hospice patients. Univariate and multivariate logistic regression analyses were conducted to identify factors associated with severe vitamin D deficiency and Coxcy and Coxional hazard analyses were used to evaluate effects on survival. Results: The mean vitamin D level in patients was $8.60{\pm}7.16ng/ml$. Vitamin D was severely deficient (<10 ng/ml) in 75 patients (78.2%), deficient (10~20 ng/ml) in 13 patients (13.5%), relatively insufficient (21~29 ng/ml) in five patients (8.3%) and sufficient ((t ng/ml) in three patients (3.1%). Hyperbilirubinemia (${\geq}1.2g/dl$) was the only factor associated with severe vitamin D deficiency according to the multiple logistic regression analysis (Odds ratio, OR=18.48, P<0.05). Although hyperbilirubinemia showed a strong association with survival (Hazard ratio, HR=2.25, P<0.01), no association was found between severe vitamin D deficiency and survival (HR=1.15, P>0.05) in Cox's proportional hazard analysis. Conclusion: Although serum vitamin D levels were severely low in terminally ill cancer patients, we found no association between severe vitamin D deficiency and patient survival.

• Korean Journal of Ecology and Environment
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• v.35 no.1 s.97
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• pp.10-20
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• 2002

Changes of seasonal and vertical water quality was analyzed with physico-chemical data from Soyang and Paldang river-reservoir system in Korea during the 1996 to 1998. In Soyang river-reservoir system, the water column was well stratified, which narrow epilimnion layer of 5 to 10 m depth in spring to summer enlarged gradually about 40 m depth in fall as going to times. In contrast, metalimnion layer tended to be narrow during the same period. Water temperature of hypolimnion was maintained about $5^{\circ}C$ continuously throughout the year. DO of the epilimnion layer was supersaturated from spring to summer, however, it was decreased to 75% at the epilimnion layer and $45{\sim}50%$ at the hypolimnion layer at the late fall. The lowest conductivity of below $50\;{\mu}S/cm$ was observed at the metalimnion layer during thesummer to fall. In Paldang river-reservoir system, the water column wag well mixed layer throughout the year, although water temperature was changed seasonally from $5^{\circ}C$ in February to $28^{\circ}C$ in July. Water temperature between upper and lower layer was different about $5^{\circ}C$ from late spring (May) to early fall (September). DO was over and less saturated in upper and lower layer during the early summer to early fall, respectively. Conductivity was decreased to $90\;{\mu}S/cm$ in lower layer of below $4{\sim}5\;m$ depth during the late spring to early fall and that of upper layer of above 10 m depth decreased to about $100\;{\mu}S/cm$ during the late fall (November) and early spring (March). Retention time of Soyang river-reservoir system was much longer than that of Paldang river-reservoir system. Chlorophyll a, T-N and T-P concentration in Paldang river-reservoir system were higher than that of Soyang river-reservoir system by a factor of 2.7, 1.2 and 2.6, respectively. Algal blooming was deeply affected by the nutrients than the retention time.