• 대한의용생체공학회:의공학회지
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• 제18권3호
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• pp.273-283
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• 1997

위전도는 피부전극을 이용하여 위에서 발생하는 전기신호를 측정하여 위운동 상태를 측정하는 검사방법이다. 여러 연구자들이 위전도를 이용하여 위수축과 관련된 정보를 얻으려고 노력하였지만 아직까지 임상적으로 유용한 정보를 주는 방법을 제시하지 못하고 있다. 본 연구에서는 위전도신호를 주파수영역 분석 및 벡터분석을 이용하여 위수축을 측정할 수 있는 방법을 제시하였다. Running spectrum analysis를 이용한 주파수영역분석에서는 주주파수와 이의 고조파의 크기변화를 위수축신호(스트레스인게이지신호, 위내압신호)와 비교하였다. 벡터분석에서는 피부전극에서 얻은 위전도신호를 이용하여 위전도벡터를 구한 후, 이 위전도벡터의 분포에 대한 분석을 실시하였다. 제시된 방법은 동물실험 및 임상실험을 통하여 그 타당성을 검정하였다. 주파수영역분석에서 위수축이 일어나는 경우 주주파수의 크기에 비해 제1고조파의 크기가 상대적을 증가하는 것을 발견하였다. 위전도 벡터분석에서는 위수축유무에 따라 위전도벡터의 분포가 변함을 알 수 있었으며, 위전도벡터의 분포로부터 계산한 회귀곡선의 기울기 및 회귀곡선에 대한 분산이 위수축유무에 따라 유의한 차이를 가지는 값을 가짐을 알 수 있었다.

• East Asian mathematical journal
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• 제24권1호
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• pp.81-95
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• 2008

Let E be a uniformly convex Banach space with a uniformly $G{\hat{a}}teaux$ differentiable norm, C a nonempty closed convex subset of E, and $T\;:\;C\;{\rightarrow}\;E$ a nonexpansive mapping satisfying the weak inwardness condition. Assume that every weakly compact convex subset of E has the fixed point property. For $f\;:\;C\;{\rightarrow}\;C$ a contraction and $t\;{\in}\;(0,\;1)$, let $x_t$ be a unique fixed point of a contraction $T_t\;:\;C\;{\rightarrow}\;E$, defined by $T_tx\;=\;tf(x)\;+\;(1\;-\;t)Tx$, $x\;{\in}\;C$. It is proved that if {$x_t$} is bounded, then $x_t$ converges to a fixed point of T, which is the unique solution of certain variational inequality. Moreover, the strong convergence of other implicit and explicit iterative schemes involving the sunny nonexpansive retraction is also given in a reflexive and strictly convex Banach space with a uniformly $G{\hat{a}}teaux$ differentiable norm.

• 대한임상전기생리학회지
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• 제7권1호
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• pp.43-48
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• 2009

Purpose : The purpose of this study was to study the effect of rectus abdominal muscle contraction by proprioceptive neuromuscular facilitation trunk stabilization training using extremity simultaneous pattern (PNF trunk stabilization training) and traditional trunk stabilization training methods. Methods : A group of 24 adults male and female, healthy, with no previous medical history nor disability in neuromuscular system and musculoskeletal system was chosen as subjects, and was divided into a control group, a PNF trunk stabilization training group and a traditional trunk stabilization training group. Experiments were performed on the last two groups, 3 times a week for 6 weeks, totaling 18 times. Using a dynamometer, muscle strength and endurance time on trunk flexion were measured before and after each experiment, and surface electromyography in left and right rectus abdominis were measured. Results : following results were obtained; 1. As for the change in the maximal voluntary isometric contraction (MVIC), all subjects in the trunk stabilization training group showed significant difference from those in the control group. 2. As for surface electromyography measurement and the changes in root mean square at the time of trunk flexion, in the left rectus abdominis, PNF trunk stabilization training group showed significant difference from the control group, while in the right rectus abdominis, traditional trunk stabilization training group showed significant difference. Conclusion : To sum up the results, both trunk stabilization training groups showed improvement in the MVIC of abdominal muscle, motor unit action potential activity, but the difference between two trunk stabilization training groups was not significant. Therefore, while trunk stabilization training significantly improved abdominal muscle contraction, but the difference attributable to training methods was found to be insignificant.

• 한국융합학회논문지
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• 제7권1호
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• pp.105-111
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• 2016

본 연구에서는 실시간 초음파 영상 분석을 통해 세 가지 골반바닥근 수축 운동이 골반바닥근과 배가로근, 배속빗근, 그리고 배바깥빗근의 두께에 미치는 영향을 분석하였다. 골반바닥근과 몸통 근육들의 근두께는 초음파 영상 장비를 이용하여 안정시, 전통적 골반바닥근 수축[운동 A]시, 엉덩 모음근과 골반바닥근 동시 수축[운동 B]시, 실시간 초음파 영상장비를 이용한 골반바닥근 수축 유도[운동 C])시 측정하였다. 측정 결과, 다른 운동들에 비해 운동 C 수행 시 안정 시 보다 가장 크게 골반바닥근의 두께가 감소하였고(p<.05), 배가로근 역시 다른 운동들에 비해 운동 C 수행 시 안정 시 보다 근두께가 가장 크게 증가하였다(p<.05). 이와 같은 결과를 바탕으로, 본 연구에서 수행한 세 가지 골반바닥근 수축 방법들 중에서 실시간 초음파 영상 장비를 이용하여 골반바닥근 수축을 유도하는 운동 C 방법이 골반바닥근 수축을 통한 여성들의 오줌새기를 개선시킬 수 있는 방법으로 추천될 수 있을 것으로 사료된다.

• Journal of Microbiology and Biotechnology
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• 제7권4호
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• pp.267-271
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• 1997

We developed a dermal equivalent (DE) which was engineered using human dermal fibroblasts and a matrix of collagen gel. The in vitro construction of the DE was accomplished by casting a porcine collagen type I solution plus concentrated medium with isolated and cultured fibroblasts. These constructs were attached to culture dishes or left floating in culture medium. Contraction of attached gels results in decreased gel thickness without a change in gel diameter, and contraction of floating gels results in decreased gel thickness and diameter. After contraction, there was no increase in cell number in floating gels, but cells in attached gels began to increase after about 4 days of the lag phase in cell growth curve. At this lag phase, addition of fibroblast growth factor (FGF) at a concentration of $0.1{\mu}$/ml promoted cell proliferation in the attached collagen gels, but no effect in floating gels. These results indicate that the method of contraction had an influence on the extracellular matrix (ECM) organization, and this influenced not only cell growth but also fibroblast responsiveness to FGF. This suggests that attached collagen gel is more suitable as a dermal equivalent than the floating gel. And the final contracted area of attached gel is much larger than that of the floating gel since floating gel is contracted in all directions but attached gel is contracted only vertically.

• 약학회지
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• 제36권5호
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• pp.496-505
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• 1992

The correlation between GABA receptors($GABA_A$ and $GABA_B$ receptor) and benzodiazepine receptor on the saline infusion-induced micturition reflex contraction was studied in the female rat. To investigate the effect of ${\gamma}-aminobutyric$ acid(GABA) on the micturition reflex, exogenous GABA(10 mg/kg) and GABA transaminase inhibitor(aminooxyacetic acid; AOAA $1\;{\mu}g$) were administered intravenously(i.v.) and intracerebroventriculary(i.c.v.), respectively. In result, both GABA and AOAA inhibited the saline induced micturition reflex contraction. This AOAA induced inhibition of micturition reflex was blocked by both bicuculine. $GABA_A$ receptor antagonist, and Ro 15-1788, benzodiazepine receptor antagonist. Muscimol, $GABA_A$ receptor antagonist($0.1\;{\mu}g$ i.c.v., $3\;{\mu}g$ intrathecal; i.t., 1 mg/kg i.v.) and baclofen, $GABA_A$ receptor agonist($1\;{\mu}g$ i.c.v., $3\;{\mu}g$ i.t., 1 mg/kg i.v.) also inhibited the bladder contraction. Pretreatment of bicuculline($1\;{\mu}g$ i.c.v.), but not of 5-aminovaleric acid(AVA, $1\;{\mu}g$ i.c.v.), $GABA_B$ receptor antagonist blocked the central inhibition of muscimol. These inhibitory effects were reversed by Ro15-1788 but were potentiated by flurazepam, benzodiazepine receptor antagonist. On the other hand, the inhibitory effects of baclofen were not affected by Ro 15-1788. Diazepam and flurazepam also inhibited the micturition reflex contraction when they were administered $3\;{\mu}g$ i.c.v., $10\;{\mu}g$ i.t., $10\;{\mu}M$, $30\;{\mu}M$ transurethrally, respectively. In conclusion, these results suggest that the micturition reflex is mediated by $GABA_A$, $GABA_B$ receptor and benzodiazepine receptor. The bezodiazepines increase the receptor binding of GABA to the $GABA_A$ receptor, so that the benzodiiazepines show the synergistic effect on the inhibition of the micturition reflex contraction, but not to the $GABA_B$ receptor.

• The Korean Journal of Physiology
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• 제24권1호
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• pp.67-76
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• 1990

The contractile mechanisms of serotonin were investigated in the renal artery of a rabbit. The helical strips of isolated renal artery were immersed in the normal or $Ca^{2+}$-free tris-buffered Tyrode's solution, which was equilibrated with 100% $O_{2}$ at $35^{\circ}C$. The contraction by serotonin or norepinephrine (NE) began at $1{\times}10^{-7}\;M$ and reached the maximal contraction at $1{\times}10^{-5}\;M$. The maximal contraction by serotonin corresponded to $58.1{\pm}4.2%$ of maximal contraction by NE. Cyproheptadine, a serotonin receptor blocker, shifted the concentration-response curve to the right without any reduction in the maximum response but shifted that of NE to the right with reduction in maximum response. And phentolamine, an ${\alpha}-receptor$ blocker, shifted the concentration-response curve of serotonin or NE without any reduction in maximum responses. The $pA_{2}$ values for cyproheptadine against serotonin and NE were $10.35{\pm}0.04$ and $8.45{\pm}0.13$, respectively. The $pA_{2}$ values for phentolamine against serotonin and NE were $6.87{\pm}0.04$ and $8.14{\pm}0.08$, respectively. after the pretreatment with 6-hydroxydopamine, the contraction induced by 100 mM $K^{+}$, tyramine and serotonin reduced to $83.0{\pm}2.0$, $26.8{\pm}6.2$ and $82.0{\pm}3.5%$ of control, respectively. The contraction by serotonin in the $Ca^{2+}$-free Tyrode's solution was increased and sustained with the addition of $Ca^{2+}$ extracellulary. The serotonin-sensitive intracellular $Ca^{2+}$ pool was depleted completely by the pretreatment with NE, but the NE-sensitive intracellular $Ca^{2+}$ pool was depleted partially by the pretreatment with serotonin. From the above results, it is suggested that the contraction induced by serotonin in the renal artery of a rabbit may be due to mechanisms in which serotonin acts directly on specific serotonin receptors and also acts indirectly on ${\alpha}-adrenoceptors$ by displacing NE from neuronal stores.

• 대한인간공학회:학술대회논문집
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• 대한인간공학회 1994년도 춘계학술대회논문집
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• pp.49-51
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• 1994

The aims of this study were first to determine the influence of vibration displacement amplitude $(200{\mu}m, 300{\mu}m peak-to-peak)$ at selected frequencies (40-200Hz) on a commonly observed but often undesired motor response elicited bylocal vibratory stimulation, the Tonic Vibration Reflex (TVR). Second, to determine the degree of synchronization of motor unit (MU) activity with vibratory stimuli. Vibration was applied to the distal tendons of the hand flexor muscles. Changes in root- mean-square electromyographic (EMG) activity of the finger and wrist flexor muscles were analyzed both as a function of their initial contraction level (0%, 10%, 20% of the maximal voluntarycontraction: MVC) and as a function of the vibration parameters. The results indicate that the TVR increased with the initial muscle contraction up to 10% MVC: The TVR increased with vibration frequency up to 100-150 Hz and decreases beyond; A significant increase of the TVR with vibration displacement amplitude was observed only for the wrist flexor muscle; MU synchronization at vibration frequency (VF) was found more often in the low frequency range $(f{\leq}100 Hz)$ and tended todecrease beyond; In the high frequency range $(f{\geq}120 Hz)$, MU activity at subharmonic frequency was predominant; The "cut-off" frequency of the synchronization with VF was neither affected by the vibration displacement amplitude nor initial muscle contraction level. The surface EMG turned out to be a useful means to analyze MU synchronization since it is noninvasive, and it can be easily used for analysis of different muscle contraction levels, while single MU technique might have some difficulties at high muscle contraction levels. Furthermore, these results indicate that high frequencyvibration (f>150 Hz) tends to induce less muscle/tendon stress and MU synchronization. Such remarks are of importance for the design of hand-held vibrating tools.ing tools.

• 한국CDE학회논문집
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• 제17권2호
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• pp.132-139
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• 2012

Presented in the paper is a procedure to extract simplified triangular mesh from a height map (terrain data). The proposed algorithm works directly on a height map that extracts a simplified triangular mesh. For the simplification, the paper employs an iterative method of edge contractions. To determine an edge to be contracted, the contraction cost of an edge is evaluated through the QEM method. Normally, an edge contraction will remove two triangles sharing the edge. Although the edge contraction can be implemented easily on a triangular mesh, it is not viable to implement the operation on a height map due to the irregular topology. To handle the irregular topology during the simplification procedure, a new algorithm is introduced.

• 대한인간공학회지
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• 제21권2호
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• pp.25-33
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• 2002

The purpose of study is to investigate the relationship between the trunk muscle fatigue and recovery time during repetitive extension by using a surface electromyogram(EMG). Ten healthy subjects particioated in a simulated lifting task with five levels of recovery time and three levels of sub-maximal contraction. EMG signals of the L1(Lumbar 1st Vertebrae) and L3(Lumbar 3rd Vertebrae) level of the erector spinae muscle were recorded. and analyzed in terms of MPF(mean power frequency) parameter to quantify the level of muscle fatigue. It was found that MPF significantly (p<0.05) decreased during repetitive extension task at 50% and 75% sub-maximal contractions. Then it took minutes for the trunk muscle to recover from fatigue during 50% sub-maximal contraction. and it took five minutes during 75% sub-maximal contraction. and it took five minutes during 75% sub-maximal contraction. The recovery time estimated by the maximum force needs to be re-evaluated for the trunk muscle to fully recover from fatigue. In conclusion. the work/rest cycle needs to be studied based upon the information of muscle fatigue in order to prevent workers from musculoskeletal injuries during repetitive lifting task.