• Title/Summary/Keyword: A-contraction

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Acetylcholine및 Oxytocin에 의하여 야기되는 렛드 자궁수축에 미치는 Verapamil 및 Tetracaine의 영향 (Effects of Verapamil and Tetracaine on Acetylcholine-and Oxytocin-induced Uterine Contraction Pattern)

  • 이만기;김중영
    • 대한약리학회지
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    • 제23권2호
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    • pp.133-141
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    • 1987
  • Acetylcholine및 oxytocin에 의하여 야기되는 흰쥐의 적출자궁수축을 $Ca^{2+}$ 길항제의 일종인 verapamil및 tetracaine 존재하에서 acetylcholine및 oxytocin에 의한 자궁수축곡선을 4개의 요소 (trough tension, T: peak tension, P; contraction frequency, F: duration, D)로 나누어 비교분석하여 다음과 같은 결과를 얻었다. Verapamil $(0.25\;{\mu}M)$은 자발수축을 억제시켰으나 tetracaine$(42\;{\mu}M)$은 자발수축을 억제시키지 못하였다. 이들 길항제의 존재하에서 acetylcholine및 oxytocin에 의하여 야기되는 자궁수축의 각 구성요소에 변화를 관찰하였다. 즉 acetylcholine에 의한 수축에서 verapamil은 P와 D를 감소시켰고 tetracaine은 F를 감소시키고 D를 증가시켰다. oxytocin에 의한 수축에서 verapamil은 P와 D를 감소시켰으나 tetracaine은 oxytocin농도에 따라 차이가 있었는데, 저농도의 oxytocin에 의한 수축에서는 F를 감소시키고 D를 증가시켰으나 고농도의 oxytocin에 의한 수축에서 는 F와 D에는 영향을 주지 않고 P만 감소시켰다. 이상의 결과로 미루어 acetylcholine및 oxytocin에 의하여 야기되는 수축곡선은 시각적으로 큰 차이가 없었으나 작용기전이 다른 $Ca^{2+}$ 길항제에 의하여 acetylcholine및 oxytocin의 수축의 구성요소에 다르게 영향을 미칠 수 있었다는 것은 수축곡선의 구성요소의 변화를 면밀히 검토하면 자궁수축제의 수축작용기전이 다름을 예측할 수 있을 뿐만 아니라 수축억제제에 의한 억제 기전의 차이점도 예측할 수 있을 것으로 생각되어 진다.

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성향정기산(星香正氣散)이 가토(家兎)의 경동맥(頸動脈) 평골근(平滑筋) 절편(切片)에서 t-Butyl Hydroperoxide 에 의한 지질과산화(脂質過酸化) 및 수축(收縮)에 미치는 영향(影響) (Effect of Sunghyangchungi-san (Xingxiangzhengqi-san) on Contraction and Lipid Peroxidation Induced by t-Butyl Hydroperoxide in Isolated Rabbit Carotid Artery)

  • 김영균;김종훈
    • 대한한의학회지
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    • 제20권3호
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    • pp.77-86
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    • 1999
  • This study was undertaken to evaluate the effect of Sunghyangchungi-san (SHCS) on the oxidant-induced contraction and lipid peroxidation in rabbit carotid artery. Vascular rings isolated from rabbit carotid artery were exposed to t-butyl hydroperoxide (t-BHP), an extrinsic oxidant, and the effect of SHCS on the changes of vascular tension and lipid peroxidation induced by t-BHP was determined. t- BHP induced a slowly developing and sustained contraction of the arterial rings. SHCS effectively relaxed the arterial rings that were pre-contracted by t-BHP. The responses to SHCS were partially dose-dependent at concentrations lower than 0.5 mg/ml. When SHCS was applied prior to the exposure to t-BHP, it inhibited the t-BHP-induced contraction as well. t- BHP increased lipid peroxidation in a dose-dependent manner. SHCS as well as well-known anti-oxidants GSH and DPPD reduced significantly lipid peroxidation induced by t-BHP. SHCS partially blocked the increase in $^{45}Ca$ uptake induced by t-BHP. In contrast to SHCS, anti-oxidants GSH and DPPD failed to inhibit significantly the t- BHP-induced contraction or $^{45}Ca$ uptake. From the above results, it is suggested that SHCS relaxed t-BHP-induced contraction of rabbit carotid artery independently of its anti-oxidant action, and inhibition of $Ca^{2+}$ influx may contribute to the underlying mechanism.

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MULTIDIMENSIONAL COINCIDENCE POINT RESULTS FOR CONTRACTION MAPPING PRINCIPLE

  • Handa, Amrish
    • 한국수학교육학회지시리즈B:순수및응용수학
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    • 제26권4호
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    • pp.277-288
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    • 2019
  • The main objective of this article is to establish some coincidence point theorem for g-non-decreasing mappings under contraction mapping principle on a partially ordered metric space. Furthermore, we constitute multidimensional results as a simple consequences of our unidimensional coincidence point theorem. Our results improve and generalize various known results.

UTILIZING ISOTONE MAPPINGS UNDER MIZOGUCHI-TAKAHASHI CONTRACTION TO PROVE MULTIDIMENSIONAL FIXED POINT THEOREMS WITH APPLICATION

  • Handa, Amrish
    • 한국수학교육학회지시리즈B:순수및응용수학
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    • 제26권4호
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    • pp.289-303
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    • 2019
  • We study the existence and uniqueness of fixed point for isotone mappings of any number of arguments under Mizoguchi-Takahashi contraction on a complete metric space endowed with a partial order. As an application of our result we study the existence and uniqueness of the solution to integral equation. The results we obtain generalize, extend and unify several very recent related results in the literature.

COMMON FIXED POINT RESULTS VIA F-CONTRACTION ON C* -ALGEBRA VALUED METRIC SPACES

  • Shivani Kukreti;Gopi Prasad;Ramesh Chandra Dimri
    • Korean Journal of Mathematics
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    • 제31권4호
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    • pp.391-403
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    • 2023
  • In this work, we establish common fixed point results by utilizing a variant of F-contraction in the framework of C*-algebra valued metric spaces. We utilize E.A. and C.L.R. property possessed by the mappings to prove common fixed point results in the same metric settings. To validate the applicability of these common fixed point results, we provide illustrative examples too.

FIXED POINT THEOREMS FOR A PAIR OF (α, η, ψ)-GERAGHTY CONTRACTION TYPE MAPS IN COMPLETE METRIC SPACES

  • P. Sudheer Kumar;G. V. V. Jagannadha Rao;R. Santhi Kumar;P. E. Satyanarayana
    • Nonlinear Functional Analysis and Applications
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    • 제29권1호
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    • pp.57-67
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    • 2024
  • In this paper, we prove the existence of common fixed point for a pair of α-η-ψ-Geraghty contraction type maps in complete metric spaces using new type of α-admissible. These results extend and generalize some of the previously known results.

엉덩관절 모음근의 수축을 동반한 플랭크 운동이 중심 근육의 두께에 미치는 영향 (The Effects of Plank Exercises with the Contraction of the Adductor Muscle of the Hip Joint on Core Muscle Thickness)

  • 고민균;송창호
    • PNF and Movement
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    • 제17권2호
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    • pp.293-302
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    • 2019
  • Purpose: The purpose of this study was to investigate the effects of plank exercises involving the contraction of the adductor muscle of the hip joint on core muscle thickness and to propose an effective plank exercise method. Methods: A total of 30 healthy young adults (17 males, 13 females) voluntarily participated in the study. The subjects were randomized to the prone plank exercise with hip adductor contraction (n=10), the prone plank exercise (n=10), and the supine plank exercise (n=10) groups. Muscle thickness measurements were taken prior to starting the exercise program and after completing the program at the end of a 4-week period. The muscle thickness of the rectus abdominis (RA), multifidus (MF), external oblique (EO), internal oblique (IO), and transverse abdominis (TrA) muscles were measured using ultrasonography. Each group performed the stipulated plank exercise five times a week as follows: 5 sets of 20 seconds during the first week, 5 sets of 30 seconds in the second week, 5 sets of 40 seconds in the third week, and 5 sets of 40 seconds in the last week. Results: The three different types of plank exercises all showed significantly increased thickness of the RA, MF, EO, IO, and TrA (P<0.05). Furthermore, changes in the thickness of both the MF and TrA were statistically more significant in the groups that did the prone plank exercise with the hip adductor contraction and the supine plank exercise than in the prone plank exercise group (P<0.05). Conclusion: The study results suggest that the prone plank exercise with hip adductor contraction is a more effective method for overall activation of the RA, MF, EO, IO, and TrA than the prone plank exercise and the supine plank exercise.

산후운동이 산욕부의 질수축압, 신체조성, 체력에 미치는 효과 (Effects of Postpartum Exercise on Pelvic Muscle Contraction, Body Composition, and Physical Fitness of the Postpartum Mother)

  • 이선옥
    • 여성건강간호학회지
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    • 제10권3호
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    • pp.244-251
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    • 2004
  • Purposes: This study was to examine the effects of postpartum exercise on pressure of the pelvic muscle contraction, body composition and physical fitness of postpartum mothers. Method: A nonequivalent pre-test, post-test control group study was conducted. Fifty-two postpartum mothers(experimental group, 26; control group, 26) admitted to a postpartum ward in a Busan mother-baby clinic were recruited. Data was analyzed using mean, $x^2$-test, and t-test by SPSS 10.0. Result: Body fat mass(t=-3.196. p= .002), body fat rate (t=-3.831, p= .000), and fat distribution(t=-3.026, p= .004) of body composition increased significantly in the experimental group after the postpartum exercise as compared with the control group. After an 8 week exercise program, the pressure of the pelvic muscle contraction in the experimental group was significantly higher than in the control group(t=3.329, p=.002). In the change of physical fitness, grip strength of the hand, back muscle strength, and trunk flexion forward were not significantly changed, but trunk backward extension in the experimental group significantly increased(t=1.950, p=.050). Conclusion: Postpartum exercise affects pelvic muscle contraction, body composition, and physical fitness of the postpartum mother.

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산욕부에게 적용한 요실금 예방 프로그램의 효과 (Effects of an Incontinence Prevention Program on Postpartum Women)

  • 정남옥
    • 여성건강간호학회지
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    • 제15권3호
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    • pp.177-185
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    • 2009
  • Purpose: This study was done to examine the effects of an incontinence prevention program on postpartum women. Methods: The study design was a nonequivalent control pretest-posttest design. The subjects were 49 postpartum women with a normal vaginal delivery, 25 in the experimental group and 24 in the control group. Data was collected from lune 1. 2007 to April 30. 2008 at a postpartum women's care center located in Jeonju, Korea. For the experimental treatment, an incontinence prevention program was carried out for 24 weeks. Measures included maximum pressure of pelvic floor muscle contraction and duration of pelvic floor muscle contraction at pre-treatment, 5 weeks postpartum and 24 weeks postpartum. Data was analyzed by Repeated ANOVA using the SPSS/WIN 14.0 program. Results: The mean maximum pressure of pelvic floor muscle contraction (F = 8.95, p < .001) and mean duration of pelvic floor muscle contraction (F = 22.01, p < .001) were significantly different between the groups, and significantly increased as time passed. Conclusion: Practice of an incontinence prevention program is considered an effective intervention for the results of fewer urinary incontinence symptoms in postpartum women.

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Classification of Premature Ventricular Contraction using Error Back-Propagation

  • Jeon, Eunkwang;Jung, Bong-Keun;Nam, Yunyoung;Lee, HwaMin
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권2호
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    • pp.988-1001
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    • 2018
  • Arrhythmia has recently emerged as one of the major causes of death in Koreans. Premature Ventricular Contraction (PVC) is the most common arrhythmia that can be found in clinical practice, and it may be a precursor to dangerous arrhythmias, such as paroxysmal insomnia, ventricular fibrillation, and coronary artery disease. Therefore, we need for a method that can detect an abnormal heart beat and diagnose arrhythmia early. We extracted the features corresponding to the QRS pattern from the subject's ECG signal and classify the premature ventricular contraction waveform using the features. We modified the weighting and bias values based on the error back-propagation algorithm through learning data. We classify the normal signal and the premature ventricular contraction signal through the modified weights and deflection values. MIT-BIH arrhythmia data sets were used for performance tests. We used RR interval, QS interval, QR amplitude and RS amplitude features. And the hidden layer with two nodes is composed of two layers to form a total three layers (input layer 0, output layer 3).