• Biomolecules & Therapeutics
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• v.25 no.1
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• pp.69-79
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• 2017

Viruses continue to evolve a new strategy to take advantage of every aspect of host cells in order to maximize their survival. Due to their central roles in transducing a variety of transmembrane signals, GPCRs seem to be a prime target for viruses to pirate for their own use. Incorporation of GPCR functionality into the genome of herpesviruses has been demonstrated to be essential for pathogenesis of many herpesviruses-induced diseases. Here, we introduce US28 of human cytomegalovirus (HCMV) as the best-studied example of virally-encoded GPCRs to manipulate host GPCR signaling. In this review, we wish to summarize a number of US28-related topics including its regulation of host signaling pathways, its constitutive internalization, its structural and functional analysis, its roles in HCMV biology and pathogenesis, its proliferative activities and role in oncogenesis, and pharmacological modulation of its biological activities. This review will aid in our understanding of how pathogenic viruses usurp the host GPCR signaling for successful viral infection. This kind of knowledge will enable us to build a better strategy to control viral infection by normalizing the virally-dysregulated host GPCR signaling.

• Journal of the Korean Society of Safety
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• v.19 no.1
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• pp.23-30
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• 2004

Modern production systems are very complex by request of automation, and failure modes that occur in thisautomatic system are very various and complex. The efficient fault diagnosis for these complex systems is essential for productivity loss prevention and cost saving. Traditional fault diagnostic system which perforns sequential fault diagnosis can cause catastrophic failure during diagnosis when fault propagation is very fast. This paper describes the Real-time Intelligent Multiple Fault Diagnosis System (RIMFDS). RIMFDS assesses current machine condition by using sensor signals. This system deals with multiple fault diagnosis, comprising of two main parts. One is a personal computer for remote signal generation and transmission and the other is a host system for multiple fault diagnosis. The signal generator generates various faulty signals and image information and sends them to the host. The host has various modules and agents for efficient multiple fault diagnosis. A SUN workstation is used as a host for multiple fault modules and agents for efficient multiple fault diagnosis. A SUN workstation is used as a host for multiple fault diagnosis and graphic representation of the results. RIMFDS diagnoses multiple faults with fast fault propagation and complex physical phenomenon. The new system based on multiprocessing diagnoses by using Hierarchical Artificial Neural Network (HANN).

• The Journal of Engineering Research
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• v.6 no.2
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• pp.125-130
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• 2004

In the current Internet, IP addresses does not support Mobility and Multi-homming because it depend on their topological location. To resolve these problems, IETF hip WG introduces Host Identity Protocol that separates the endpoint identifier and locator roles of IP addresses. However the DNS that was presented for the HIP had only a part of the expansion design from the existing DNS function, so it was not an absolute complete method. This paper propose how the dymanic DNS has been designed so that it support the HIP completely. We added the Host Identity Namespace and the Rendezvous Server Namespace, defined the new PRs in DNS.

• Mycobiology
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• v.50 no.3
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• pp.166-171
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• 2022

Virginia creeper (or five-leaved ivy; Parthenocissus quinquefolia) is one of the most popular and widely grown climbers worldwide. In September 2021, Virginia creeper leaves with typical rust symptom were found in an arboretum in Korea, with severe damage. Globally, there is no record of a rust disease on Virginia creeper. Using morphological investigation and molecular phylogenetic inferences, the rust agent was identified as Neophysopella vitis, which is a rust pathogen of other Parthenocissus spp. including Boston ivy (P. tricuspidata). Given that the two ivy plants, Virginia creeper and Boston ivy, have common habitats, especially on buildings and walls, throughout Korea, and that N. vitis is a ubiquitous rust species affecting Boston ivy in Korea, it is speculated that the host range of N. vitis may recently have expanded from Boston ivy to Virginia creeper. The present study reports a globally new rust disease on Virginia creeper, which could be a major threat to the ornamental creeper.

• Korean journal of applied entomology
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• v.51 no.3
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• pp.265-269
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• 2012

The Korean Boletoxenus known as fungivorous are taxonomically reviewed as two species including a new recorded species, Boletoxenus incurvatus (Lewis, 1894). And the host fungus of B. incurvatus is revealed through this study. Therefore, we provide the taxonomical information as well as the ecological information on the host fungi of the Korean Boletoxenus species.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.156-158
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• 2009

New liquid crystal (LC) host mixtures and reactive mesogens (RMs) designed for the Polymer Sustainable Vertically Aligned (PS-VA) mode have been developed. The novel combination of LC host mixture with RMs enables to show superior LC display performance with high reliability and to contribute for the robust LC panel production process.

• Journal of the Korea Society of Computer and Information
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• v.8 no.4
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• pp.126-131
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• 2003

While the advantages of multicast delivery over multiple unicast deliveries is undeniable, the deployment of the IP multicast protocol has been limited to network domains under single administrative control. Deployment of inter-domain multicast delivery has been slow due to both technical and administrative reasons. For this reasons overlay multicasting technologies are recently proposed. We propose a End-Host Multicast Tree Protocol (EMTP) that searches two levels of the tree at a time until reaching to a leaf node and can select the nearest node that a new node try to join in the tree. Even if there is no available degree of the desirable node that a new node want to join, selecting the node as a potential parent by EMTP can reduce the number of tree switching with robustness of the tree and bring to ruduce the data delivery time.

• Journal of Microbiology and Biotechnology
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• v.20 no.10
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• pp.1463-1470
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• 2010

E. coli has long been widely used as a host system for the manufacture of recombinant proteins intended for human therapeutic use. When considering the impurities to be eliminated during the downstream process, residual host cell DNA is a major safety concern. The presence of residual E. coli host cell DNA in the final products is typically determined using a conventional slot blot hybridization assay or total DNA Threshold assay. However, both the former and latter methods are time consuming, expensive, and relatively insensitive. This study thus attempted to develop a more sensitive real-time PCR assay for the specific detection of residual E. coli DNA. This novel method was then compared with the slot blot hybridization assay and total DNA Threshold assay in order to determine its effectiveness and overall capabilities. The novel approach involved the selection of a specific primer pair for amplification of the E. coli 16S rRNA gene in an effort to improve sensitivity, whereas the E. coli host cell DNA quantification took place through the use of SYBR Green I. The detection limit of the real-time PCR assay, under these optimized conditions, was calculated to be 0.042 pg genomic DNA, which was much higher than those of both the slot blot hybridization assay and total DNA Threshold assay, where the detection limits were 2.42 and 3.73 pg genomic DNA, respectively. Hence, the real-time PCR assay can be said to be more reproducible, more accurate, and more precise than either the slot blot hybridization assay or total DNA Threshold assay. The real-time PCR assay may thus be a promising new tool for the quantitative detection and clearance validation of residual E. coli host cell DNA during the manufacturingprocess for recombinant therapeutics.

• Korean journal of applied entomology
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• v.59 no.4
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• pp.357-360
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• 2020

We identified Jolcham oak (Quercus serrata Thunb. ex Murray) (Fagales: Fagaceae) as a new host tree for Callipogon relictus Semenov (Coleoptera: Cerambycidae), a Korean natural monument and an endangered species, in Gwangneung Forest, South Korea. We herein report the morphometric characteristics of C. relictus larvae found in a Q. serrata tree and provide a revised list of C. relictus hosts.

• KIPS Transactions on Computer and Communication Systems
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• v.2 no.8
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• pp.327-334
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• 2013

Today's network traffic has become extremely complex and diverse since the speed of network became faster and a variety of application services appear. Moreover, many applications appear and disappear fast and continuously. However, the current traffic classification system does not give much attention to this dynamic change of applications. In this paper, we propose an application awareness system in order to solve this problem. The application awareness system can provide the information, such as the usage trend of conventional applications and the emergence of new applications by recognizing the application name in a rapidly changing network environment. In order to recognize the application name, the Host field of HTTP protocol has been utilized. The proposed mechanism consists of two steps. First, the system generates the candidates of application name by extracting the domain name from the Host field in HTTP packet. Second, the administrator confirms the name afterward. The validity of the proposed system has been proved through the experiments in campus network.