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Study on Relationship between constitution medicine and Prostaglandin E2 in Blood (사상인(四象人) 체질(體質)과 혈중(血中) Prostaglandin E2치(値)와의 관계(關係)에 관(關)한 연구(硏究))

  • Kim, Jong-Weon
    • Journal of Sasang Constitutional Medicine
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    • v.9 no.2
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    • pp.245-261
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    • 1997
  • The investigation were carried out the 37 patient with cerebrovascular accidents who had been treated in Oriental Medical Hospital in Kyung Hee University and in KangNam Uy Lim, and the 10 examinees who had been worked in Medical Hospital in Kyung Hee University. The consitution which had discriminated by survey, which had discriminated by study on the morphological diagrammings, which had discriminated by the result of the impatient of hospital on a dosage of constitutial prescription. The Prostaglandin E2 in blood for 47 persons (37 patients & 10 examinees) was measured. The following results were obtained. 1.In the constitution which had discriminated by survey, in the value of Prostaglandin E2 in bood of ammong four constitutiens didn,t showed significant differance. 2.In the constitution which had discriminated by study on the morphological diagrammings, in the value of Prostaglandin E2 in bood of ammong four constitutiens didn,t showed significant differance. 3.In the constitution which had discriminated by the result of patient of hospital on a dosage of constitutial prescription, the value of Prostaglandin E2 in blood of among four constitutions didn,nt showed signicant differance. 4.In the constitution which had discriminated by colligated three methods(survey, morphological diagrammings,the result of patient of hospital on a dosage of constitutial prescription), the value of Prostaglandin E2 in blood of ammong four constituion didn,t showed significant differnce. 5.In the constitution which had discriminated by survey, a test of significance between the value of Prostaglandin E2 in blood of each constitution and the value of Prostaglandin E2 in blood of the others was conducted. Only the value of Prostaglandin E2 in blood between in the TAE-EUM-IN(太陰人) and the others of female showed significant differance. 6.In the constitution which had discriminated by study on the morphological diagrammings,a test of significance between the value of Prostaglandin E2 in blood of each constitution and the value of Prostaglandin E2 in blood of the others was conducted. Only the value of Prostaglandin E2 in blood between in the SO-EUM-IN(少陰人) and the others of male showed significant differance. 7.In the constitution whichhad discriminated by the result of patient of hospital on a dosage of constitutial prescription,a test of significance between the value of Prostaglandin E2 in blood of each constitution and the value of Prostaglandin E2 in blood of the others was conducted. Only the value of Prostaglandin E2 in blood between in the TAE-EUM-IN(太陰人) and the others of male showed significant differance. 8.In the constitution which had discriminated was the colligated three methods(survey,morphological diagrammings,the result of patient of hospital on a dosage of constitutial prescription),a test of significance between the value of Prostaglandin E2 in blood of each constitution and the value of Prostaglandin E2 in blood of the others didn,t showed significant differnce. In this connected study is inadequete at present. But if the study is done persistently,the analysis of various ingredient in the body enables objectification in differentiation of four types of physical constitution as the supplemental method.

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EQUATIONS AX = Y AND Ax = y IN ALGL

  • Jo, Young-Soo;Kang, Joo-Ho;Park, Dong-Wan
    • Journal of the Korean Mathematical Society
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    • v.43 no.2
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    • pp.399-411
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    • 2006
  • Let L be a subspace lattice on a Hilbert space H and X and Y be operators acting on a Hilbert space H. Let P be the projection onto $\frac\;{R(X)}$, where RX is the range of X. If PE = EP for each $E\;\in\;L$, then there exists an operator A in AlgL such that AX = Y if and only if $$sup\{{\parallel}E^{\bot}Yf{\parallel}/{\parallel}E^{\bot}Xf{\parallel}\;:\;f{\in}H,\; E{\in}L}=K\;<\;\infty$$ Moreover, if the necessary condition holds, then we may choose an operator A such that AX = Y and ${\parallel}A{\parallel} = K.$ Let x and y be vectors in H and let $P_x$ be the projection onto the singlely generated space by x. If $P_xE = EP_x$ for each $E\inL$, then the assertion that there exists an operator A in AlgL such that Ax = y is equivalent to the condition $$K_0\;:\;=\;sup\{{\parallel}E^{\bot}y{\parallel}/{\parallel}E^{\bot}x\;:\;E{\in}L}=<\;\infty$$ Moreover, we may choose an operator A such that ${\parallel}A{\parallel} = K_0$ whose norm is $K_0$ under this case.

Development of Wear Model concerning the Depth Behaviour

  • Kim, Hyung-Kyu;Lee, Young-Ho
    • KSTLE International Journal
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    • v.6 no.1
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    • pp.1-7
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    • 2005
  • Wear model for predicting the vehaviour of a depth is considered in this paper. It is deduced from the energy and volume based wear models such as the Archard equation and the workrate model. A new parameter of the equivalent depth ($D_e$= wear volume /worn area) is considered for the wear model of a depth prediction. A concenpt of a dissipated shear energy density is accommodated for in the suggested models. It is found that $D_e$ can distinguish the worn area shape. A cubic of $D_e$($D_e^3$) gives a better linear regression with the volume than that of the maximmum depth $D_{max}e$($D_{max}^3$) does. Both $D_{max}$ and $D_e$ are used for the presently suggested depth-based wear model. As a result, a wear depth profile can be simulated by a model using $D_{max}$. Wear resistance from the concern of an overall depth can be identified by the wear coefficient of the model using $D_e$.

Combustion Characteristics of E.V.A., Rubber Waste Treatment by Fixed-Bed Incinerator. (E.V.A., 고무폐기물 소각에 따른 폐가스 처리의 연구)

  • Bae, Byung-Hoon;Jang, Seong-Ho;Lim, Gyoung-Teck
    • Journal of Environmental Science International
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    • v.5 no.2
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    • pp.221-227
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    • 1996
  • The objectives of this study are to examine combustion characteristics of E.V.A. and rubber wastes by fixed-bed incinerator, The results are as follows. Combustion temperature with time rises rapidly, and mass of E.V.A. reduces at short time in E.V.A. combustion. In variation of air-fuel ratio (m), ice ideal values of m of E.V.A. and rubber are 2.5, 1.5 respectively. Mixed-waste combustion is more economic than single E.V.A. combustion, because we can get high combustion efficiency (94.0~99.0%) at 2.0 air-fuel ratio of mixed-waste combustion. Removal efficiencies of SO2 at cooling tower are about 20%. The combustion efficiencies of rubber are over 98.0% according to the experimental conditions.

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A Study on the Development of the e-Marketplace on Fisheries Sector in Gangwon Do (강원도 수산물 분야 e-Marketplace 활성화 방안에 관한 연구)

  • Eom, Kwang-Yeol
    • International Commerce and Information Review
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    • v.7 no.3
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    • pp.53-75
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    • 2005
  • Owing to the Digital revolution, Internet Commerce and Electronic Commerce is having a profound influence on the global Market and internal commerce, revolutionizing the way of doing business. e-Marketplace have adopted in order to the reshape of the Fisheries Sector's competitiveness, and it is now being utilized as a major global marketing instrument to develop new customers, save Market transaction costs ad facilitate new work processes. The purpose of this study is to provide a program for activation in e-Marketplace of the Fisheries Sector in Gangwon Do. However, at present, the environment of e-Marketplace Infrastructure in Gangwon Do is very poor. Therefore, this study points out the problems of e-Marketplace of the Fisheries Sector in Gangwon Do and provides many considerations for a program for activation of e-Marketplace.

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A Study on the Effect of e-CRM on the Reuse Intention of e-Learning Service (이러닝 서비스의 e-CRM이 재이용의도에 미치는 영향에 관한 연구)

  • Hong, Kyu Jeong;Kang, Min Jung
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.383-396
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    • 2021
  • This study attempts to verify the effect of e-CRM on reuse intetnion of e-learning and to determine whether the presense mediates the relationship between e-CRM and reuse intetnion of e-learning through empirical analysis. The results of the study are as follows. First, The effect of e-CRM(e-marketing, e-service, e-communication) on the intention of reuse for e-learning services was significant. Second, it was found that the effect of e-CRM(e-marketing, e-service) on reuse intention of e-learning was significantly mediated by the teaching presence. Third, it was found that the effect of e-CRM(e-marketing, e-service, e-communication) on reuse intention of e-learning was significantly mediated by the cognitive presence. Finally, it was found that the effect of e-CRM(e-marketing) on reuse intention of e-learning was significantly mediated by the social presence.

The Attenuation Mechanism and Live Vaccine Potential of a Low-Virulence Edwardsiella ictaluri Strain Obtained by Rifampicin Passaging Culture

  • Shuyi Wang;Jingwen Hao;Jicheng Yang;Qianqian Zhang;Aihua Li
    • Journal of Microbiology and Biotechnology
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    • v.33 no.2
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    • pp.167-179
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    • 2023
  • The rifampicin-resistant strain E9-302 of Edwardsiella ictaluri strain 669 (WT) was generated by continuous passage on BHI agar plates containing increasing concentrations of rifampicin. E9-302 was attenuated significantly by 119 times to zebrafish Danio rerio compared to WT in terms of the 50% lethal dose (LD50). Zebrafish vaccinated with E9-302 via intraperitoneal (IP) injection at a dose of 1 × 103 CFU/fish had relative percentage survival (RPS) rates of 85.7% when challenged with wild-type E. ictaluri via IP 14 days post-vaccination (dpv). After 14 days of primary vaccination with E9-302 via immersion (IM) at a dose of 4 × 107 CFU/ml, a booster IM vaccination with E9-302 at a dose of 2 × 107 CFU/ml exhibited 65.2% RPS against challenge with wild-type E. ictaluri via IP 7 days later. These results indicated that the rifampicin-resistant attenuated strain E9-302 had potential as a live vaccine against E. ictaluri infection. A previously unreported amino acid site change at position 142 of the RNA polymerase (RNAP) β subunit encoded by the gene rpoB associated with rifampicin resistance was identified. Analysis of the whole-genome sequencing results revealed multiple missense mutations in the virulence-related genes esrB and sspH2 in E9-302 compared with WT, and a 189 bp mismatch in one gene, whose coding product was highly homologous to glycosyltransferase family 39 protein. This study preliminarily explored the molecular mechanism underlying the virulence attenuation of rifampicin-resistant strain E9-302 and provided a new target for the subsequent study of the pathogenic mechanism of E. ictaluri.

Integration of WFST Language Model in Pre-trained Korean E2E ASR Model

  • Junseok Oh;Eunsoo Cho;Ji-Hwan Kim
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.18 no.6
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    • pp.1692-1705
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    • 2024
  • In this paper, we present a method that integrates a Grammar Transducer as an external language model to enhance the accuracy of the pre-trained Korean End-to-end (E2E) Automatic Speech Recognition (ASR) model. The E2E ASR model utilizes the Connectionist Temporal Classification (CTC) loss function to derive hypothesis sentences from input audio. However, this method reveals a limitation inherent in the CTC approach, as it fails to capture language information from transcript data directly. To overcome this limitation, we propose a fusion approach that combines a clause-level n-gram language model, transformed into a Weighted Finite-State Transducer (WFST), with the E2E ASR model. This approach enhances the model's accuracy and allows for domain adaptation using just additional text data, avoiding the need for further intensive training of the extensive pre-trained ASR model. This is particularly advantageous for Korean, characterized as a low-resource language, which confronts a significant challenge due to limited resources of speech data and available ASR models. Initially, we validate the efficacy of training the n-gram model at the clause-level by contrasting its inference accuracy with that of the E2E ASR model when merged with language models trained on smaller lexical units. We then demonstrate that our approach achieves enhanced domain adaptation accuracy compared to Shallow Fusion, a previously devised method for merging an external language model with an E2E ASR model without necessitating additional training.

Distinct Humoral and Cellular Immunity Induced by Alternating Prime-boost Vaccination Using Plasmid DNA and Live Viral Vector Vaccines Expressing the E Protein of Dengue Virus Type 2

  • George, Junu A.;Eo, Seong-Kug
    • IMMUNE NETWORK
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    • v.11 no.5
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    • pp.268-280
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    • 2011
  • Background: Dengue virus, which belongs to the Flavivirus genus of the Flaviviridae family, causes fatal dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with infection risk of 2.5 billion people worldwide. However, approved vaccines are still not available. Here, we explored the immune responses induced by alternating prime-boost vaccination using DNA vaccine, adenovirus, and vaccinia virus expressing E protein of dengue virus type 2 (DenV2). Methods: Following immunization with DNA vaccine (pDE), adenovirus (rAd-E), and/or vaccinia virus (VV-E) expressing E protein, E protein-specific IgG and its isotypes were determined by conventional ELISA. Intracellular CD154 and cytokine staining was used for enumerating CD4+ T cells specific for E protein. E protein-specific CD8+ T cell responses were evaluated by in vivo CTL killing activity and intracellular IFN-${\gamma}$ staining. Results: Among three constructs, VV-E induced the most potent IgG responses, Th1-type cytokine production by stimulated CD4+ T cells, and the CD8+ T cell response. Furthermore, when the three constructs were used for alternating prime-boost vaccination, the results revealed a different pattern of CD4+ and CD8+ T cell responses. i) Priming with VV-E induced higher E-specific IgG level but it was decreased rapidly. ii) Strong CD8+ T cell responses specific for E protein were induced when VV-E was used for the priming step, and such CD8+ T cell responses were significantly boosted with pDE. iii) Priming with rAd-E induced stronger CD4+ T cell responses which subsequently boosted with pDE to a greater extent than VV-E and rAd-E. Conclusion: These results indicate that priming with live viral vector vaccines could induce different patterns of E protein-specific CD4+ and CD8+ T cell responses which were significantly enhanced by booster vaccination with the DNA vaccine. Therefore, our observation will provide valuable information for the establishment of optimal prime-boost vaccination against DenV.

e-AIRS: Construction of an Aerodynamic Integrated Research System on the e-Science Infrastructure (e-AITS: e-Science 인프라 기반의 항공우주 공력통합연구 환경구축)

  • Kim, Jin-Ho;Yi, Jun-Sok;Ko, Soon-Heum;Ahn, Jae-Wan;Kim, Chong-Am;Kim, Yoon-Hee;Cho, Kum-Won
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.5
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    • pp.428-437
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    • 2008
  • e-AIRS, an abbreviation of ‘e-Aerospace Integrated Research System’, is a virtual organization designed to support the aerospace engineering processes in the e-Science environment. As the first step toward a virtual aerospace engineering organization, the e-AIRS intends to give a full support to aerodynamic research processes. Currently, the e-AIRS can handle both the computational and experimental aerodynamic researches on the e-Science infrastructure. In detail, users can conduct the full CFD(Computational Fluid Dynamics) research processes, request wind tunnel experiments, perform the comparative analysis between computational and experimental resultants and finally collaborate with other researchers using the web portal. The current paper will describe those functions and the internal architecture of the e-AIRS system.