• Korean Journal of Remote Sensing
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• v.38 no.5_2
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• pp.707-723
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• 2022

Although satellite-based sea surface temperature (SST) is advantageous for monitoring large areas, spatiotemporal data gaps frequently occur due to various environmental or mechanical causes. Thus, it is crucial to fill in the gaps to maximize its usability. In this study, daily SST composite fields with a resolution of 4 km were produced through a two-step machine learning approach using polar-orbiting and geostationary satellite SST data. The first step was SST reconstruction based on Data Interpolate Convolutional AutoEncoder (DINCAE) using multi-satellite-derived SST data. The second step improved the reconstructed SST targeting in situ measurements based on light gradient boosting machine (LGBM) to finally produce daily SST composite fields. The DINCAE model was validated using random masks for 50 days, whereas the LGBM model was evaluated using leave-one-year-out cross-validation (LOYOCV). The SST reconstruction accuracy was high, resulting in R² of 0.98, and a root-mean-square-error (RMSE) of 0.97℃. The accuracy increase by the second step was also high when compared to in situ measurements, resulting in an RMSE decrease of 0.21-0.29℃ and an MAE decrease of 0.17-0.24℃. The SST composite fields generated using all in situ data in this study were comparable with the existing data assimilated SST composite fields. In addition, the LGBM model in the second step greatly reduced the overfitting, which was reported as a limitation in the previous study that used random forest. The spatial distribution of the corrected SST was similar to those of existing high resolution SST composite fields, revealing that spatial details of oceanic phenomena such as fronts, eddies and SST gradients were well simulated. This research demonstrated the potential to produce high resolution seamless SST composite fields using multi-satellite data and artificial intelligence.

• The Korean Society of Law and Medicine
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• v.22 no.1
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• pp.91-124
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• 2021

In May 2019, the Ministry of Food and Drug Safety revised the "Pharmaceutical Determination and Adjustment Criteria" with the content of differentially calculating the price of generic drugs according to the registration of the drug substance and meeting the requirements for their own bioequivalence test. According to this revised rule, if their own bioequivalence test is not conducted, even the generic drugs that have already been approved would be lowered in price. I wondered whether this system was introduced with sufficient public legal considerations regarding its legislative purposes and means. Therefore, I reviewed the contents of the revised notice based on whether or not it is valid to determine and adjust the price of generic drugs in terms of the legitimacy of legislative purposes and the proportionality principle after introducing the history and background of the rule. First, I raised a question as to whether the purpose of preventing the overrun of generic drugs is indeed legitimate in terms of the legitimacy of the purpose. In order for the revised notice of "reduction of drug prices when the test requirements are not met," to meet the conformity principle, the premise that it is difficult to recognize safety and effectiveness through consignment (joint) bioequivalence test or that these tests are insufficient in safety and efficacy verification than their own test must be established. Nevertheless, it seems that suffficient review has not been carried out. In order to achieve the purpose of securing safety and effectiveness, the focus should be on 'reinforcement of the standards for bioequivalence test and the management of the bioequivalence test itself' rather than whether it is a their own test or a consignment (joint) test. Third, it is contrary to the necessity and substantiality principle that strict standards are uniformly applied to the products that can be considered to have been sufficiently verified for safety and effectiveness after a considerable period of time has passed after the product approval. In many cases, revised administrative legislations quickly enacted and amended in the state of lack of legal review or consensus, while the regulatory effects resulting from it are quite direct and specific to the regulated person. In this respect, I emphasized that the administrative legislative process also requires substantial review and prior control of the regulatory purposes and means, and that the participation of stakeholders in the legislative procedure is to be strengthened.

• Korean Journal of Mineralogy and Petrology
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• v.35 no.4
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• pp.447-455
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• 2022

Fully dehydrated Tl₁₂-LTA (|Tl₁₂|[Si₁₂Al₁₂O₄₈]-LTA,Tl₁₂-A) was treated with 6.0×10³ Pa of ZrI₄ (g) at 623 K for 72 hr under anhydrous conditions. The crystal structure of product, |Zr_0.25I_1.5Tl₁₂|[Si₁₂Al₁₂O₄₈]-LTA, was determined by single-crystal crystallography using synchrotron X-radiation in the cubic space group Pm3m (a = 12.337(2) Å). It was refined using all data to the final error index (for the 712 unique reflections for which F_o> 4σ(F_o) R₁/wR₂= 0.055/0.189. In this structure, octahedral ZrI₆^2- ions center about 25% of the large cavities (Zr-I = 2.91(4) Å). Each coordinates to eight Tl⁺ ions and they are further bridged by Tl⁺ ions in the planes of 8-rings to form a cubic three-dimensional ZrI₆Tl₁₁⁹⁺ cationic cluster. About 1.5 Tl⁺ ions per unit cell moved to deeper side of sodalite cavity after reaction with ZrI₄(g). The remaining Tl⁺ ions occupy well-established cation positions near 6- and 8-rings.

• Journal of the Korean Orthopaedic Association
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• v.55 no.2
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• pp.162-168
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• 2020

Purpose: The purpose of this study was to suggest an appropriate treatment method by comparing nonsurgical treatment and surgical treatment for enchondroma in the hands and feet. Materials and Methods: Seventy four cases with enchondroma of the hands and feet from January 1996 to March 2017 were selected to evaluate the functional outcomes. Thirty cases were treated with nonsurgical treatment, and 44 cases were treated with surgical treatment, such as curettage only or curettage with a bone graft. The mean follow-up period was 18.1 months. The functional results were analyzed using the Wilhelm and Feldmeier formula. Results: The mean age was 38 years, and the age range was between eight and 69 years. According to the Wilhelm and Feldmeier formula, the mean score of hand enchondroma was 3.09±0.85 and 3.20±0.91 in the non-operative and operative group, respectively. The mean scores of the foot except for the grip strength were 2.57±0.79 and 2.75±0.50, respectively. No significant difference was observed according to the functional results. Among the 18 cases of enchondroma with pathological fractures, nine cases were treated non-surgically and nine cases were treated by surgically. In all 18 cases, complete bone healing was observed at the final follow-up. Conclusion: Relatively satisfactory results were obtained in both surgical and nonsurgical treatment and there was no significant difference in functional outcomes. In cases of enchondroma in the hands and feet, nonsurgical treatment can also be a good treatment option.

• Research in Plant Disease
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• v.28 no.2
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• pp.82-91
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• 2022

Recently, several in vitro studies have reported antiviral activity of agents of systemic acquired resistance against plant virus infection, but the approach has not been applied in a wide range of agricultural fields. The objective of this study was to evaluate the inhibitory effect of the exogenous application of salicylic acid (SA), chitosan (CH), or eugenol (EG) in tomato yellow leaf curl virus (TYLCV) infection of greenhouse-grown tomato plants. In vitro, the initial time of symptom was observed in TYLCV-infected plants (VP) of the resistant cultivar 'Superdotaerang' at 12 days post inoculation (dpi) after application of antiviral agents. At 32 dpi, the disease rate of TYLCV in the CHT+VP (0.1% chitosan and virus infected control) treated plants was 87.5%, lower than that of the other treatment. However, the virus content in the CHT+VP treated plants was higher than those of the other treatments, and SA, EG, and CH did not show significant effect on plant height or shoot and root fresh weight. Our results from summer-cultivated greenhouse-grown tomatoes show that none of the tested agents had an inhibitory activity on viral infection or yield of tomato 'Dotaerangsola'cultivar. In contrast, all treated 'TY Giants' cultivars that possessed TYLCV resistance genes Ty-1 and Ty-3a did not show typical symptoms and the virus content was remarkably lower than those in the TYLCV treated plants in 'Superdotaerang'. The results of this research indicated that the planting of resistant tomato cultivars was effective method instead of using SA, EG, and CH (known as resistance-inducing factors for control) of TYLCV in the field.

• Microbiology and Biotechnology Letters
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• v.50 no.3
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• pp.337-346
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• 2022

The purpose of this study was to investigate the antioxidant and anti-inflammatory activities of hot water (AMPW) and 70% ethanol (AMPE) extracts of apple mango (Mangifera indica L.) peel. The antioxidant activities were measured using a total polyphenol, electron-donating, 2,2'-azinobis [3-ethylbenzothiazoline6-sulfonic acid] (ABTS) radical scavenging assay. The total polyphenol content of AMPW and AMPE was 66.08 ± 0.62 mg TAE/100 g and 100.13 ± 0.23 mg TAE/100 g, respectively. As a result of measuring the electrondonating ability, at a concentration of 1,000 ㎍/ml, AMPW and AMPE showed an effectiveness of 86% and 94%, respectively. The ABTS assay showed 80% and 98% respective radical scavenging activity for AMPW and AMPE, at a concentration of 1,000 ㎍/ml. The cell viability on macrophage cells was performed using a 3-[4,5-dimethyl-thiazol-2-yl]-2,5-diphenyl-tetrazoliumbromide (MTT) assay, and the results showed more than 90% cell viability at a 100 ㎍/ml concentration. Anti-inflammatory activity was verified by confirming nitric oxide (NO) production inhibitory activity, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) protein and mRNA expression inhibitory activity from lipopolysaccharide (LPS)-treated RAW 264.7 cells. The NO production inhibitory effects were measured using the Griess assay, which confirmed 45% and 40% inhibition after treatment with AMPW and AMPE, respectively. Moreover, the protein and mRNA expression of inflammatory-related factors iNOS and COX-2, decreased in a concentrationdependent manner. In conclusion, this study showed antioxidant and anti-inflammatory effects of Mangifera indica L. peel and revealed its promising potential for application as an antioxidant and anti-inflammatory agent.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.67-67
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• 2023

수문관측의 핵심은 강우-유출 관계다. 하천유량 생산을 위해 수많은 지점에서 유량측정을 수행한다. 그러나 유량자료의 신뢰도는 높지 않다. 그리고 댐 유입량 산정에 아무 도움이 되지 않고 있다. 더구나 저수지의 경우는 유입량 자료도 없이 운영되고 있다. 저수지, 댐에 물이 고여 있는데 이를 활용하면 유입량을 계산할 수 있고, 그 지점에서 유량이 얼마인지 고품질로 생산할 수 있다. 여기서는 총저수량 260만m³, 유역면적 3.7km²인 감포댐에 적용하여 저수량 자료를 활용하여 유입량의 신뢰도를 얼마나 개선시킬 수 있는지 분석한 결과는 다음과 같다. 여기서 적용 기간은2020.9.1.~9.14., 2022.9.5.~9.6 등 2개 사상이고, ONE 모형에 의해 10분 단위로 유출량을 모의했다. 모의 방법은 총유량을 같게 하는 방법과 저수위 오차를 최소로 하는 방법 등 두 가지로 했다. 첫째, 2020.9.1.~9.14. 사상은 강우량은 10분 최대 19.0mm, 총 127.0mm였다. 총유량을 같게 하는 경우 유입량은 10분 최대 5.4m³/s, 총 40만m³로 모의돼, 유출률 85.5%로 나타났고, 관측은 10분최대 4.7m³/s, 총 40만m³, 유출률 85.3%로 나타났다. 유량 신뢰도는 RMSE 0.491mm, NSE 0.237, R²는 0.455로 나타났다. 이 경우 저수위 모의 신뢰도는 RMSE 0.600m, NSE 0.158, R²는 0.893로나타났다. 저수량 오차를 최소로 한 경우 유입량은 10분 최대 4.0m³/s, 총 28만m³로 모의돼, 유출률 59.4%로 나타났고, 관측은 10분 최대 4.0m³/s, 총 28만m³, 유출률 85.3%로 나타났다. 유량 신뢰도는 RMSE 0.425mm, NSE 0.430, R²는 0.507로 나타났다. 이 경우 저수위 모의 신뢰도는 RMSE 0.110m, NSE 0.972, R²는 0.995로 높았다. 둘째, 2022.9.5.~9.6. 사상은 강우량은 10분 최대 32.3mm, 총 196.0mm였다. 총유량을 같게 하는 경우 유입량은 10분 최대 64.5m³/s, 총 59만m³로 모의돼, 유출률 81.6%로 나타났고, 관측은 10분 최대 80.1m³/s, 총 59만m³, 유출률 81.6%로 나타났다. 유량 신뢰도는 RMSE 1.832mm, NSE 0.960, R²는 0.984로 나타났다. 이 경우 저수위 모의 신뢰도는 RMSE 0.323m, NSE 0.968, R²는 0.999로나타났다. 저수량 오차를 최소로 한 경우 유입량은 10분 최대 80.1m³/s, 총 66만m³로 모의돼, 유출률 91.6%로 나타났고, 관측은 10분 최대 80.1m³/s, 총 59만m³, 유출률 81.8%로 나타났다. 유량 신뢰도는 RMSE 2.120mm, NSE 0.947, R2는 0.949로 나타났다. 이 경우 저수위 모의 신뢰도는 RMSE 0.153m, NSE 0.993, R²는 0.997로 높았다. 종합하면 저수량 오차가 최소가 되도록 하천 유출량을 모의하면 결과적으로 하천유량의 신뢰도를 향상시키는 것이라 말할 수 있다.

• Journal of Mushroom
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• v.21 no.1
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• pp.1-7
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• 2023

This study addresses the current demand of the Korean mushroom export industry to establish an export strategy and governing policies.The enoki mushroom exports increased by 89% in 2009 and 23% in 2010, resulting in the largest export volume (17,163 tons) and export value ($26,292,000) being recorded in 2010. In contrast, exports in 2020 yielded only $18,525,000, which was 29% lower than that in 2010. In case of king oyster mushrooms, exports increased by 10% in 2012, 13% in 2013, and 2% in 2014, maintaining a moderate-growth trend. Moreover, Korea's mushroom exports are focused on a few specific countries. Enoki mushrooms accounted for more than 50% of the total exports to North America and Vietnam from 2012 to 2022, whereas king oyster mushrooms accounted for more than 50% of the total exports to Europe and North America (USA and Canada) from 2009 to 2022. Another characteristic trend in Korean mushroom exports is the diversification of export markets. The number of countries importing enoki mushrooms and king oyster mushrooms from Korea is increasing.

• Journal of the Korean Geotechnical Society
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• v.23 no.9
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• pp.5-16
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• 2007

The simple linear elastic-perfectly plastic model with soil parameters $s_u,\;E_u$ and n of undrained condition is usually applied to predict the displacement of a constructed diaphragm wall(DW) on soft soils during excavation. However, the application of this soil model for finite element analysis could not interpret the continued increment of the lateral displacement of the DW for the large and deep excavation area both during the elapsed time without activity of excavation and after finishing excavation. To study the characteristic behaviors of soil behind the DW during the periods without excavation, a series of tests on soft Bangkok clay samples are simulated in the same manner as stress condition of soil elements happening behind diaphragm wall by triaxial tests. Three kinds of triaxial tests are carried out in this research: $K_0$ consolidated undrained compression($CK_0U_C$) and $K_0$ consolidated drained/undrained unloading compression with periodic decrement of horizontal pressure($CK_0DUC$ and $CK_0UUC$). The study shows that the shear strength of series $CK_0DUC$ tests is equal to the residual strength of $CK_0UC$ tests. The Young's modulus determined at each decrement step of the horizontal pressure of soil specimen on $CK_0DUC$ tests decreases with increase in the deviator stress. In addition, the slope of Critical State Line of both $CK_0UC$ and $CK_0DUC$ tests is equal. Moreover, the axial and radial strain rates of each decrement of horizontal pressure step of $CK_0DUC$ tests are established with the function of time, a slope of critical state line and a ratio of deviator and mean effective stress. This study shows that the results of the unloading compression triaxial tests can be used to predict the diaphragm wall deflection during excavation.

• Knowledge Management Research
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• v.23 no.4
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• pp.91-112
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• 2022

In order to improve the quality of consumption in senior generation, it is necessary to build trust in the digital consumption environment. However, there are limitations from previous researches on consumption in the digital environment that has mainly focused on Millennial and Z generations. Therefore, this study aims to examine the antecedents of digital consumption trust and to explore the market segments of senior generation created by the dynamics of these antecedents. In addition, in order to provide practical implications, we investigate the difference in the level of perceived digital consumption trust using segmentation. This study, therefore, used 2021 Korea's consumer life index data conducted by the Korea Consumer Agency for general consumers, and only consumer data of 60s and older are extracted for the analysis. As a result, we confirm from the main results that the three antecedents, consumer competency, perceived corporate responsibility, and local community's problem-solving environment, are significant in building the digital consumption trust in the senior generation. It is academically significant in this aspect to look at approaches to improve senior customers' trust in digital consumption circumstances by dividing generations because generations exhibit varying levels of understanding of online consumption or digital consumption conditions. It is academically significant in this aspect to look at approaches to improve senior customers' trust in digital consumption circumstances by dividing generations because generations exhibit varying levels of understanding of online consumption or digital consumption conditions. Additionally, it is proposed as a practical implication that it should be managed so that significant improvements of customers, businesses, and regional public institutions are developed in order to allow the senior consumers to prepare trusted digital consumption circumstances.