• Clinical Nutrition Research
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• v.12 no.4
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• pp.257-268
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• 2023

Migraine is a common neurological disease correlated with oxidative stress and lipid profile disorders. The present study was designed to determine the effects of Coenzyme Q10 (Co-Q10) supplementation on oxidative status and lipid profile in migraine individuals. This clinical trial was conducted on 84 females aged 18-50 years, diagnosed for episodic migraine according to the International Headache Society. Subjects were randomized to receive either Co-Q10 supplement (400 mg/day) or placebo for 12 weeks. Lipid profile and oxidative stress indices including malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured before and after intervention in both groups. Also, anthropometric indices, dietary intakes, and clinical features were collected. Data analysis was conducted using SPSS version 16. Seventy-seven of the participants, with mean age of 33.70 ± 7.75 years, completed the study. After 12-week intervention, Co-Q10 led to a significant decrease in MDA levels compared to placebo (p = 0.009), with no effect on TAC levels (p = 0.106). A significant increase in serum Co-Q10 concentration and high-density lipoprotein cholesterol (HDL-C) level in Co-Q10 group was observed, but no significant differences were found in other lipid profile variables (low-density lipoprotein cholesterol, triglycerides and total cholesterol). Among anthropometric variables, Co-Q10 only caused a significant reduction in body fat percentage (BFP), but we did not find any significant changes in others. A 12-week Co-Q10 supplementation led to significant improvement in clinical features, BFP, and HDL-C level among migraine individuals.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.7
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• pp.1015-1020
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• 2018

The cavity resonator is one of the widely used components in the microwave applications. The unloaded Q, the resonant frequency, and the coupling factor are basic parameters of a cavity. A simple unloaded Q factor measurement procedure of a cavity is proposed in a lossy coupling. The equivalent circuit of a cavity with coupling loss at near the resonant frequency is presented. The coupling loss resistance was found by the measurement of a cavity impedance. The cavity impedance compensated coupling loss was redrawn on the Smith Chart. The loaded Q and coupling factor were obtained based on the compensated impedance locus and then the unloaded Q factor was calculated. To verify the proposed procedure, the cavity with lossless coupling was measured. The two measurement results in the lossy and lossless coupling agree well. The results confirm the proposed procedure is valid.

• The Journal of the Korea Contents Association
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• v.22 no.2
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• pp.431-446
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• 2022

In this study, the characteristics of the experiences and perceptions of vulnerable adolescents on the school environment were explored and categorized, and of which the meanings were confirmed. For this purpose, Q methodology was used, and 94 Q samples were extracted by analyzing pre-interviews, literature analysis, and media search contents to form a Q population. Q classification was performed on the subjects. The schools belonging to the sample P are 7 high schools in Seoul and 4 high schools in Gyeonggi-do. As a result of analyzing the data collected in Q sorting using QUANL-PC program, a Q analysis program, it was classified into 4 types. Type 1 is 'a conformal and moeling type', and Type 2 is 'negative and defiant type', Type 3 is 'passive and helpless type' and Type 4 is 'progressive and struggling type'. Through this study, it is expected that this study will be able to understand the experiences and perceptions of the school environment of underprivileged adolescents, and to obtain the necessary clues for realistic support strategies for them.

• Korean Journal of Adult Nursing
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• v.26 no.5
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• pp.522-532
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• 2014

Purpose: This study's purpose is to classify and analyze caregivers' recognition of the elderly suicidal intents. Methods: This study uses applied Q-methodology to measure human subjectivity in depth. Concretely, 35 statements are composed in depth interviews and literature investigation. Then, Q-cards and distributive chart of Q-sampling were given to 25 caregivers randomly-selected, who were asked to arrange them on a 7-score based. After coding Q-factor analysis is carried out with the PC-QUANL program. Results: Four types of indicators of the elderly suicidal intents were identified by the caregivers. These are Knowledge-based recognition, Behavioral measure based recognition, Negative comprehension and Sympathy. Conclusion: In this study, four types of recognition were yielded among the caregivers and the characteristics of each type were analyzed. These findings may be useful in assessing suicidal potential and nursing interventions.

• Journal of Nutrition and Health
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• v.55 no.1
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• pp.120-140
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• 2022

Purpose: The purpose of the study was to investigate whether adherence to the Korea Healthy Eating Index (KHEI) was associated with metabolic syndrome and risk markers. Methods: The participants included 8,345 adults, aged 20-59 years, who took part in the 7th Korea National Health and Nutrition Examination Survey (KNHANES). The data were analyzed using a complex-sample t-test, the Rao Scott χ²-test, and logistic regression analysis on the SPSS v. 26.0 software. The participants were divided into four groups by quartiles of KHEI scores. Results: The average KHEI score was 61.06 points out of 100, and the women's score (62.50 points) was significantly higher than that of men (59.63 points). The KHEI quartiles status showed significant differences by age (p < 0.001), household income (p < 0.001), smoking status (p < 0.001), and food security. Specifically, the KHEI quartiles in the men showed significant differences in education (p < 0.001) and economic activity (p < 0.001) whereas those of women showed significant differences in alcohol-consumption (p < 0.001), depression (p < 0.01) and eating-out (p < 0.001). As the KHEI scores increased, the proportion of subjects with an energy intake below the estimated energy requirement (EER) was lower, and significantly better levels of intake were observed for carbohydrate, protein, vitamin C, calcium, vitamin B₁, vitamin B₂, and niacin. The incidence of the metabolic syndrome risk factors, hypertriglyceridemia and hyperglycemia for men and hypertension, and hyperglycemia for women showed significant differences. The KHEI scores were inversely associated with abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, hyperglycemia, hypertension, and metabolic syndrome. Conclusion: Based on these results, we conclude that higher adherence to the KHEI was associated with lower metabolic syndrome risk factors and incidence of the metabolic syndrome.

• The Korean Journal of Nuclear Medicine Technology
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• v.21 no.2
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• pp.31-36
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• 2017

Purpose Recently, the performance of PET/CT scanner has been improved and various techniques have been developed to increase the image quality such as Sensitivity and Resolution. The purpose of this study is to evaluate the usefulness of Q.Clear (a fully convergent iterative reconstruction) technique of GE Discovery IQ equipment to enhance the image quality. Materials and Methods All scans were acquired by Discovery IQ (GE Healthcare, MI, USA). In NEMA IEC Body Phantom test, Background to Hot-sphere (10 mm, 13 mm, 17 mm, 22 mm) ratio was 1:4 and scan time was 3 minutes. The images were reconstructed by VPHDs (VUE Point High-Definition + SharpIR) and Q.Clear to evaluate each Contrast. We injected 18F-FDG 187 M㏃ to PET/SPECT Performance Phantom. And then it was scanned for 4 minutes to evaluate Resolution and Uniformity. T-test statistical analysis was performed on SUVmax of small lesions less than 2 cm in 100 clinical patients regardless of disease type. Results In the NEMA IEC Body Phantom, the Contrast was $63.6{\pm}5.7%$ (VPHDs) and $75{\pm}4.8%$ (Q.Clear). In the PET/SPECT Performance Phantom, the Resolution was 9.2 mm (VPHDs) and 7.3 mm (Q.Clear). Uniformity of Q.Clear was 10.8% better than VPHDs. T-test statistic of the clinical patients showed a significant difference of p value of 0.021. Conclusion Both the phantom test and the clinical results showed that the quality of the image was improved in Q.Clear was applied. The SUVmax was highly measured in Q.Clear and the lesions were clearly distinguished visually. Therefore Q.Clear can be useful in various aspects such as dose-reduction, patients evaluation and image analysis.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.601-601
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• 2015

비홍수기 하천유량관리는 정해진 기준 이상으로 유량을 유지하는 데 목적을 두며 유량관리를 위한 기준유량으로는 하천유지유량이나 하천관리유량이 주로 사용되고 있다. 이들 기준유량과 함께 최근에는 하천 유량 변화를 효과적으로 파악하고 유량변화에 따른 갈수상황을 객관적으로 판단하기 위한 의사결정 도구로 갈수지표가 활용되고 있다. 본 연구에서는 낙동강 주요 홍수예보지점의 하나인 진동지점을 대상으로 유량자료를 수집하고 갈수지표를 이용한 유량평가를 실시하였다. 다양한 갈수지표 중 특정기간을 대상으로 일정시간 가장 낮은 유량을 갈수지표로 활용하는 기법과 동일기간 유량자료의 저유량백분위 기준을 적용하여 이를 갈수임계값으로 활용하는 기법을 적용하였다. 전자는 7Q10(Singh, 1974)이 대표적이며 이는 10년 중 가장 낮은 값을 갖는 7일의 유량이 갈수의 기준이 된다. 본 연구에서는 7Q10의 기간을 20년으로 확대한 7Q20을 적용하였다. 후자는 WMO(2008)에서 적용된 바 있으며 본 연구에서는 1~12월의 월별 저유량90분위(Q90)를 갈수임계값으로 선정하였다. 신뢰할 수 있는 장기유량자료의 활용을 위해 "장기 수문자료 검증 및 평가연구"(한강홍수통제소, 2011)를 통해 수정, 보완된 진동지점의 과거 20년간(1994~2013) 유량자료를 활용하였으며 갈수지표와 함께 유량관리를 위한 기준유량으로 활용되는 하천유지유량(2006년 고시)과 하천관리유량(2013년 기준)의 유량만족도를 비교하였다. 과거 가뭄발생 및 제한급수시기, 강수량 등과 비교했을 때 월별 갈수임계값(Q90)을 갈수지표로 활용한 경우가 갈수관리에 효과적이라 판단되었다. 해당 기법은 통계학적 유의성을 갖기 위해서 장기수문자료의 활용이 필요하나 유량의 시계열 변동특성 반영이 가능하므로 우리나라와 같이 갈수기와 홍수기의 구분이 명확하고 하상계수가 큰 지역에서는 장점을 갖는 것으로 판단된다.

• Journal of Environmental Health Sciences
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• v.20 no.3
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• pp.19-30
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• 1994

Regarding to Q fever which is one of the most important zoonoses in Food (Milk) Hygiene and in Environmental Public Health, a sero-epidemiological study was carried out to detect the complement fixation antibodies to Coxiella burnetii Nine Mile strain phase II antigen among the milking cows in Kyunggi Province. The results obtained were summarized as follows: 1. The overall prevalence of the CF antibodies to Q fever among 989 milking cows of 75 dairy farms in Kyunggi Province was revealed as high as 58.7% by the farms and 27.8% by the individual cows with higher prevalence in Kyunggi Central and Kyunggi East regions than any other regions in the Province. 2. Anticomplementary reactions were appeared as 7.5% (74/989) and it ranged from 1.0% to 16.0% according to the regions investigated. 3. In the titration of the positively reacted sera, the figures of 16.7%, 37.5%, 29.8%, 9.5%, 2.9% and 3.6% at the serum dilutions of 1: 10, 1: 20, 1: 40, 1: 80, 1: 160 and higher than 1: 160, respectively. 4. It was recognized that the relatively higher cumulated frequency distribution of the CF antibodies was shown in the sera collected from the regions with higher prevalence of Q fever. 5. There was a high correlation between the prevalence of Q fever CF antibodies and the age which is usually equivalent to one year older than the calving history of the milking cows.

• BMB Reports
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• v.37 no.5
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• pp.522-526
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• 2004

Prader-Willi (PWS) and Angelman (AS) are syndromes of developmental impairment that result from the loss of expression of imprinted genes in the paternal (PWS) or maternal (AS) 15q11-q13 chromosome. Diagnosis on a clinical basis is difficult in newborns and young infants; thus, a suitable molecular test capable of revealing chromosomal abnormalities is required. We used a variety of cytogenetic and molecular approaches, such as, chromosome G banding, fluorescent in situ hybridization, a DNA methylation test, and a set of chromosome 15 DNA polymorphisms to characterize a cohort of 27 PWS patients and 24 suspected AS patients. Molecular analysis enabled the reliable diagnosis of 14 PWS and 7 AS patients, and their classification into four groups: (A) 6 of these 14 PWS subjects (44%) had deletions of paternal 15q11-q13; (B) 4 of the 7 AS patients had deletions of maternal 15q11-q13; (C) one PWS patient (8%) had a maternal uniparental disomy (UPD) of chromosome 15; (D) the remaining reliably diagnoses of 7 PWS and 3 AS cases showed abnormal methylation patterns of 15q11-q13 chromosome, but none of the alterations shown by the above groups, although they may have harbored deletions undetected by the markers used. This study highlights the importance of using a combination of cytogenetic and molecular tests for a reliable diagnosis of PWS or AS, and for the identification of genetic alterations.

• Journal of Life Science
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• v.28 no.3
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• pp.314-319
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• 2018

We analyzed QTLs for alkali-related digestion by using 120 population crossed Cheongcheong and Nagdong derived from anther culture (CNDH). The DNA markers located in the QTLs gene were selected and applied to existing cultivars. As a result of the investigation of the alkali decay degree, brown rice of Cheongcheong and Nagdong was 1.9 and 1.6, respectively, and the CNDH was $3.79{\pm}2.01$, and the distribution of variance was distributed to 7.0-1.0. The milled rice of Cheongcheong and Nagdong was 5.6 and 4.1, respectively. The mean of the CNDH was $4.86{\pm}1.55$, and the distribution of variance was distributed to 7.0-2.0. Variation distribution curves showed continuous variation that was close to non-normal distribution. In the QTLs analysis, qBRA2, qBRA6, and qBRA11 were mapped in 1-2 replications of brown rice. QHRA2-1, qHRA2-2, qHRA2-3, qHRA3, and qHRA8 were mapped in the first replication. QHRA2-1, qHRA2-2, qHRA2-3 and qHRA3 were mapped in the second replicates. And mapped to qHRA5 in 4 replicates. These were found on chromosome 2, 3, 6, 8 and 11, respectively. The phenotypic variations of qBRA2, qBRA6, and qBRA11 on the chromosomes of brown and milled rice were 1-9%. The polymorphism was analyzed for 12 types of the japonica type and six types of the indica type, based on the nine markers found in the QTLs analysis of alkali digestion. Chromosome 11, RM27258, was selected to determine the segregation ratio, which shows the difference in size by the band pattern. The results of this study will be used as basic data for the development of high-quality rice cultivars.