• Toxicological Research
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• 제35권4호
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• pp.353-359
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• 2019

The purpose of this study was to investigate the effect of $7-MEGA^{TM}$ 500 on the improvement of skin aging in an UVB-induced photo-aging model of hairless mice. The dorsal skin of hairless mice was exposed to UVB three times a week for 12 weeks to induce skin wrinkle. After inducing the wrinkle, $7-MEGA^{TM}$ 500 was orally administered once a day for 4 weeks. Skin thickness, skin barrier function, and wrinkle indicators were improved by treatment with $7-MEGA^{TM}$ 500. Both gene and protein expression levels of MMP-3 and c-Jun in skin were significantly decreased by $7-MEGA^{TM}$ 500. Therefore, the intake of $7-MEGA^{TM}$ 500 is thought to have a positive effect on the improvement of skin aging, although further studies are needed.

• Toxicological Research
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• 제34권2호
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• pp.103-110
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• 2018

Environmental stimuli can lead to the excessive accumulation of reactive oxygen species (ROS), which is one of the risk factors for premature skin aging. Here, we investigated the protective effects of $7-MEGA^{TM}$ 500 (50% palmitoleic acid, 7-MEGA) against oxidative stress-induced cellular damage and its underlying therapeutic mechanisms in the HaCaT human skin keratinocyte cell line (HaCaT cells). Our results showed that treatment with 7-MEGA prior to hydrogen peroxide ($H_2O_2$)-induced damage significantly increased the viability of HaCaT cells. 7-MEGA effectively attenuated generation of $H_2O_2$-induced reactive oxygen species (ROS), and inhibited $H_2O_2$-induced inflammatory factors, such as prostaglandin $E_2$ ($PGE_2$), tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), and $interleukin-1{\beta}$ ($IL-1{\beta}$). In addition, cells treated with 7-MEGA exhibited significantly decreased expression of matrix metalloproteinase-1 (MMP-1) and increased expression of procollagen type 1 (PCOL1) and Elastin against oxidative stress by $H_2O_2$. Interestingly, these protective activities of 7-MEGA were similar in scope and of a higher magnitude than those seen with 98.5% palmitoleic acid (PA) obtained from Sigma when given at the same concentration (100 nL/mL). According to our data, 7-MEGA is able to protect HaCaT cells from $H_2O_2$-induced damage through inhibiting cellular oxidative stress and inflammation. Moreover, 7-MEGA may affect skin elasticity maintenance and improve skin wrinkles. These findings indicate that 7-MEGA may be useful as a food supplement for skin health.

• International Journal of Advanced Culture Technology
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• 제7권4호
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• pp.321-326
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• 2019

As AI technology is recently introduced into various fields, it is being applied to the fashion field. This paper proposes a system for recommending cody clothes suitable for a user's selected clothes. The proposed system consists of user app, cody recommendation module, and server interworking of each module and managing database data. Cody recommendation system classifies clothing images into 80 categories composed of feature combinations, selects multiple representative reference images for each category, and selects 3 full body cordy images for each representative reference image. Cody images of the representative reference image were determined by analyzing the user's preference using Google survey app. The proposed algorithm classifies categories the clothing image selected by the user into a category, recognizes the most similar image among the classification category reference images, and transmits the linked cody images to the user's app. The proposed system uses the ResNet-50 model to categorize the input image and measures similarity using ORB and HOG features to select a reference image in the category. We test the proposed algorithm in the Android app, and the result shows that the recommended system runs well.

• 국제초고층학회논문집
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• 제10권3호
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• pp.193-201
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• 2021

Cheongna City Tower is a 448-meter-high rise observatory tower with 8.7:1 aspect ratio located at central lake park in Incheon Cheongna international city. The tower is a crystal shaped image and it turns invisible when the façade is activated. The tower was planned to be hexagonal 30-story building with two basements which are composed of mega frame structure using mega column and mega brace. In order to minimize the wind effect, the blow-through area was installed so that the wind can pass through. This observatory tower is an unprecedented project since the whole building is covered by façade for invisibility effect.

• Journal of Plant Biology
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• 제6권1호
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• pp.1-7
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• 1963

Two individuals of intergeneric hybrids in the crossing of Brassica pekinensis ♀$\times$Raphanus sativus ♂ were obtained, and among the three kinds of plants, Brassica, Raphanus, and F1, comparison on the mega- and microsporogenesis, megagammetophyte formation, and morphological changes in the developing sporangia, etc., were made. Differences between Brassica and Raphanus were observed in the shape of mega- and microsporangia, their changes in development, and the formation of megagametophyte. Sporangia of the F1 plants, until pre-meiotic stage, show intermediate, maternal, paternal, or vigorous inclination, and the difference of these characteristics when compared with those of the parent is slight. Meiotic irregularity resulted from the intergeneric hybridity of F1 plant gives rise to the abnormal mega- and microspore and accompanied abortive female and male gametophytes, bringing about the remarkable differences from its parent in the morphological changes of the developing mega- and microsporangia.

• 한국항해항만학회지
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• 제29권7호
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• pp.635-640
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• 2005

This paper aims to understand and analyze the mega-trends such as trends towards larger vessels due to an increasing trade volume, accordingly fewer port calls, strategic alliances and M&A Increasing degree of concentration through M&A activities in shipping industry results in a decreasing number of shipping finns with an increasing share in the world shipping capacity. But competition is strongly increasing on main trunk routes. Therefore, shipping concentration directly leads to further concentration of port traffic in fewer and larger ports with an increasing competition among neighboring ports.

• 웰빙융합연구
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• 제7권2호
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• pp.39-47
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• 2024

This study investigates the impact of mega-influencers and micro-influencers on consumer trust, brand attitude, and purchase intention within the beauty industry. Methods: A survey of 160 adults was conducted in March 2024, analyzing responses to the influence of a beauty mega-influencer ("Isa Bae") and a micro-influencer ("Day Beauty"). Participants were surveyed online over two weeks, and the data were analyzed using statistical tools to compare the influence of both types of influencers. Results: The results indicated that mega-influencers had a more substantial effect on reliability and brand attitude compared to micro-influencers, although both types of influencers significantly influenced purchase intentions. Influencer attractiveness and expertise emerged as critical factors in shaping consumer perceptions and behaviors. Conclusion: This study provides insights into optimizing influencer marketing strategies by leveraging the distinct characteristics and scales of influencers to enhance consumer engagement and brand loyalty. The findings underscore the importance of choosing the appropriate influencer type to maximize marketing effectiveness and consumer trust in the digital marketing landscape.

• 섬유기술과 산업
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• 제7권4호
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• pp.428-434
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• 2003

• 대한건축학회논문집:구조계
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• 제35권7호
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• pp.147-156
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• 2019

The purpose of this study is to consider structural issues and analyze construction sequences when constructing hanging floors supported by Mega truss. Since suspended structures were supported by the Mega truss, vertical load on suspended structures was needed to transfer from low to high. Deflection management of structures was the primary point under construction. The results of this study were as follows; The steel structures, which has relatively lighter self-weight, were constructed upwards after the base floor steel truss erection. Concrete Placing, which has relatively heavier self-weight, were performed in two phases to minimize structure's deflection. Slab was placed downwards from the top floor to lower floor whereas column was places upwards. Deflection measurements were carried out at every construction sequences.

• 한국콘텐츠학회논문지
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• 제10권11호
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• pp.318-328
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• 2010

본 광역권별 경제력 비교분석은 정부의 지역경제정책에 대한 기초연구로서 콜드스타트(cold start)된 5+2광역경제권의 상이한 경제여건과 펀더멘털을 고찰하고 설정된 비교지표를 중심으로 전국 7대 광역권의 지역경제력을 비교 분석해 봄으로써 글로벌 경쟁력 확보 차원에서 자립적 광역경제권을 육성한다는 정부의 지역경제정책의 타당성과 향후 광역경제권의 정책방향을 고찰하는데 목적을 두고 있다. 경제력지수 비교결과, 수도권의 경제력지수가 절대 우위에 있는 반면 강원권, 호남권, 제주권은 상대적 열위상태인 것으로 조사되었다. 지역의 특성과 경제적 펀더멘털이 다르기 때문에 향후 지역발전 및 광역경제권 정책을 추진함에 있어서는 이를 고려한 세심한 배려와 발전계획 수립이 필요할 것으로 보인다. 그리고 정부는 지역경제여건을 감안한 광역경제권사업의 지역안배와 조정을 통하여 지역사업의 중복성 문제를 원천 차단함으로써 재정의 효율성을 제고시켜야 할 것이다. 또한 수요분석에 기초한 demand-based policy와 demand-pull policy, 지역낙후성을 감안하여 예산균등할(豫算均等割)정책보다는 비균등할 지원책을 탄력적으로 사용함으로써 지역균형발전을 도모하여야 할 것으로 사료된다.