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버전 상호 호환 가능한 HL7 파서의 설계 (Design of an Version-Compatible HL7 Parser)

  • 이인근;황도삼
    • 한국어정보학회:학술대회논문집
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    • 한국어정보학회 2017년도 제29회 한글및한국어정보처리학술대회
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    • pp.201-202
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    • 2017
  • 의료정보시스템의 상호운용을 위해 개발된 의료정보 교환 국제 표준인 HL7은 복잡한 구조와 문법으로 인해 컴퓨터 소프트웨어로 관리되고 있다. 현재 개발되고 있는 HL7 인터페이스 소프트웨어에서는 다양한 버전 간 호환이 되지 않아 의료정보시스템에서 버전 상호 간의 호환을 위해 변환 소프트웨어 모듈을 개발하여 사용한다. 그러나 다양한 버전(V2.1~V2.8)의 HL7 메시지 간 상호 변환을 위해 소프트웨어 모듈을 모두 개발하는 것은 많은 시간과 막대한 비용 및 노력이 필요한 비효율적인 방법이다. 따라서 본 연구에서는 HL7 버전 호환성 정의에 기반을 두어 버전별 상호변환이 가능한 HL7 파서(Parser)를 설계하고, 객체 지향적 구조에 기반을 두어 하위 버전과의 호환(Backward Compatibility)뿐만 아니라 상위 버전과 호환(Forward Compatibility) 가능한 파서를 제안한다. 또한, 버전 간 변환 실험을 통해 효용성을 검증하였다.

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The Pathophysiologic Roles of TRPM7 Channel

  • Park, Hyun Soo;Hong, Chansik;Kim, Byung Joo;So, Insuk
    • The Korean Journal of Physiology and Pharmacology
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    • 제18권1호
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    • pp.15-23
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    • 2014
  • Transient receptor potential melastatin 7 (TRPM7) is a member of the melastatin-related subfamily and contains a channel and a kinase domain. TRPM7 is known to be associated with cell proliferation, survival, and development. It is ubiquitously expressed, highly permeable to $Mg^{2+}$ and $Ca^{2+}$, and its channel activity is negatively regulated by free $Mg^{2+}$ and Mg-complexed nucleotides. Recent studies have investigated the relationships between TRPM7 and a number of diseases. TRPM7 regulates cell proliferation in several cancers, and is associated with ischemic cell death and vascular smooth muscle cell (VSMC) function. This review discusses the physiologic and pathophysiologic functions and significance of TRPM7 in several diseases.

전자건강기록시스템을 위한 HL7 메시지 서버 프로토타입 설계 및 구현 (Design and Implementation of a Prototype HL7 Message Server for LEX : Lifelong Electronic Health Record Based on XML)

  • 유수영;김보영;최진욱
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2001년도 가을 학술발표논문집 Vol.28 No.2 (3)
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    • pp.463-465
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    • 2001
  • 본 논문에서는 향후 의료분야에서 활용하게 되는 표준화 기반기술을 개발함을 주된 목표로 HL7 메시지 서버 구축에 필요한 소프트웨어 프레임워크의 디자인 및 구현에 대해서 기술하였다. HL7 표준은 의료 환경에서의 전자적 데이터 교환을 위한 이벤트 중심의 어플리케이션 프로토콜로서, 메시지 단위로 정보의 전송이 이루어진다. 이와 같은 의료정보 교환의 기본 단위인 HL7 메시지를 만들기 위해서 연구진들은 중간 계층의 인터페이싱 방식의 유효성을 고려하여 인터페이스 엔진에 해당하는 HL7 메시지 서버를 구축하였다. HL7 메시지 서버는 병원점보시스템에 연결되어 약속된 이벤트가 발생할 때마다 해당하는 HL7 메시지를 자동적으로 생성하는 서버 시스템으로서, 현재 운영되고 있는 국내병원정보시스템에 HL7 표준을 쉽게 적용시킬 수 있는 최적의 솔루션을 제공해 줄 것이다.

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$CsTiP_2O_7$의 합성과 결정구조 (Synthesis and Crystal Structure of $CsTiP_2O_7$)

  • 김대영;동용관;이건수;윤호섭
    • 한국결정학회지
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    • 제10권1호
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    • pp.51-55
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    • 1999
  • Cesium titanium(III) pyrophosphate 화합물인 CsTiP2O7을 합성하고 X절 회절법을 이용하여 그 결정구조를 해석하였다. 이물질은 단사정계의 P21/a 공간군으로 결정화되었고 a=8.369(2) , b=10.208(2) , c=7.752(1) , β=104.77(2)o, V=640.4(2) 3, and Z=4이다. 이 물질의 구조는 모서리를 공유하고 있는 TiO6 팔면체와 P2O7 pyrophosphate group들로 구성된 framework로 구성되어 있으며 그 결과로 형성된 tunnel 안에는 Cs+이온이 존재한다. CsTiP2O7은 ATiP2O7(A=K, Rb)와 KAIP2O7 그리고 AMoP2O7(A=K, Rb, Cs)등 다른 +3금속 pyrophosphate들로 유사한 구조를 가지고 있다. 이 물질은 [Cs+][Ti3+][P2O74-]의 식으로 표현할 수 있다.

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Methyl-7-oidoheptanoate의 합성에 관한 연구 (Study on Synthesis of Methyl-7-iodoheptanoate)

  • 심영섭;최종욱;김완주;박호군;박영숙
    • 약학회지
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    • 제30권6호
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    • pp.348-351
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    • 1986
  • New synthetic method for methyl-7-iodoheptanoate was studied. Methyl-7-iodoheptanoate is important compound in the synthesis codlemone, the sex pheromone of codling moth which doing harm to apple tree significantly, and this compound also be used essentially in the synthesis of prostaglandin derivatives. In previous the methyl-7-iodoheptanoate has been prepared from-7-chloroheptanoic acid as a starting material with disadvantage, since the 7-chloroheptanoic acid is expensive and the process is much complicate. In this paper the method to preparing methyl-7-iodoheptanoate was developed economically by using dihydropyran as a starting material in the course of 5 steps. Hence, methyl-7-iodoheptanoate which can be synthesized by new method studied onthis paper should be very useful compound for preparing codlemone or its acetate which will be used to developing pollution-free insecticides, and for preparing prostaglandin derivatives with advantage.

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Isolation and Characterization of Soil Strains Producing Glutaryl-7-Aminocephalosporanic Acid Acylase

  • Knang, Yong-Ho;Yoo, Ryong-Hoon
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제2권2호
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    • pp.105-108
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    • 1997
  • A search was undertaken to screen microorganisms that produce an enzyme capable of deacylating glutary1-7-amincephalosporanic acid to 7-aminocephalosporanic acid in soil samples. The screening was carried out by preparing enrichment cultures containing glutary-7ACA and cephalosporin C as selective carbon sources. A non-${\beta}$-lactam model compound,, glutary-p-nitroanilide, was synthesized as a substrate suitable for the rapid screening of microorganisms isolated from the enrichment cultures. Two isolates exhibiting acylase activity, designated BY7.4 and BY8.1, were identified as strains of Pseudomonas species. Pseudomonas BY8.1 showed higher acylase activity toward G1-7ACA than Pseudomonas BY7.4. Environmental conditions for the optimal acylase activity of Pseudomonas BY8.1 were shown to be pH9 and 30$^{\circ}C$.

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크롬탄화물형 크롬백철 오버레이 용착금속에서의 $(Cr,\;Fe)_7C_3$의 경도특성 (Characteristics of Hardness of $(Cr,\;Fe)_7C_3$ in the Chromium-Carbide-Type Chromium White Iron Hardfacing Weld Deposits)

  • 백응률
    • Journal of Welding and Joining
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    • 제23권2호
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    • pp.75-80
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    • 2005
  • The effect of chemical constituents of $(Cr,\;Fe)_7C_3$ carbide phase on its hardness in the chromium-carbide type Cr white iron hardfacing weld deposits has been investigated. In order to examine $(Cr,\;Fe)_7C_3$ carbide phase, a series of filler metals with varying chromium contents was used. The alloys were deposited once or twice on a mild steel plate using the self?shielding flux cored arc welding process. The hardness of $(Cr,\;Fe)_7C_3$ carbide phase was measured by the micro-Vickers hardness test. It was shown that hardness of $(Cr,\;Fe)_7C_3$ carbide phase increased with increasing Cr content in $(Cr,\;Fe)_7C_3$ carbide phase. This behavior of the hardness of $(Cr,\;Fe)_7C_3$ carbide phase was explained by the types of chemical bonds that hold atoms together in $(Cr,\;Fe)_7C_3$ carbide phase.

살구씨의 화학적 조성에 관한 연구 (A Studies on the Chemical Composition of Apricot Seed)

  • 이성민;임효진
    • 한국식품영양학회지
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    • 제5권1호
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    • pp.1-6
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    • 1992
  • For the effective utilization of apricot seed resources of food protein and lipid, the general composition, amino acid composition and chemical characteristics were analysed. The skinned and non-skinned apricot seed contained 53.9% and 48.0% of crude lipid, 24.7% and 26.8% of crude protein, respectively. There were no significant difference in the amino acid composition among skinned and non-skinned apricot seed, The major amino acids were glutamic acid, aspartic acid, alanine, tyrosine and threonine, holding 14.6 to 16.9%, 12.4 to 13.7%, 9.2 to 12.1%, 7.2 to 7.5% and 7.0 to 7.2% of total amino acid content, respectively. The sum of these ammo acids occupied about 50% to total amino acids. While the quantities of methionine, histidine, and Lysine were poor content. The essential amino acids occupied about 30% to total amino acids. The acid, iodine and saponification value of apricot seed oil were 0.7 to 7.1, 80.8 to 107.5 and 182.7 to 208.4, respectively. These values were significant difference in skinned and non-skinned apricot seed.

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T7 발현체계에서 chloramphenicol acetyltransferase의 선택적 과잉생산 (Selective overproduction of chloramphenicol acetyltransferase in the T7 expression system)

  • 김한복;강창원
    • 미생물학회지
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    • 제27권4호
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    • pp.317-322
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    • 1989
  • A gene can be selectively overexpressed in E. coli by utilizing the phage T7 RNA polymerase's stringent recognition and active transcription of the T7 promoter. The T7 expression system was constructed such that the T7 RNA polymerase gene is under the control of lacUV5 promoter in one plasmid, and that the target gene, the promoterless chloramphenicol acetyltransferase (CAT) gene with E. coli ribosome binding site is under the control of T7 promoter in the other plasmid. Only the E. coli cells containing both plasmids show high resistance to chloramphenicol. When the copy number of the runaway plasmid containing the polymerase gene was varied by a temperature shift, amounts of the CAT protein synthesized upon induction was correspondingly changed as shown in SDS gel electrophoresis.

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The Convolution Sum $\sum_{al+bm=n}{\sigma}(l){\sigma}(m)$ for (a, b) = (1, 28),(4, 7),(1, 14),(2, 7),(1, 7)

  • Alaca, Ayse;Alaca, Saban;Ntienjem, Ebenezer
    • Kyungpook Mathematical Journal
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    • 제59권3호
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    • pp.377-389
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    • 2019
  • We evaluate the convolution sum $W_{a,b}(n):=\sum_{al+bm=n}{\sigma}(l){\sigma}(m)$ for (a, b) = (1, 28),(4, 7),(2, 7) for all positive integers n. We use a modular form approach. We also re-evaluate the known sums $W_{1,14}(n)$ and $W_{1,7}(n)$ with our method. We then use these evaluations to determine the number of representations of n by the octonary quadratic form $x^2_1+x^2_2+x^2_3+x^2_4+7(x^2_5+x^2_6+x^2_7+x^2_8)$. Finally we express the modular forms ${\Delta}_{4,7}(z)$, ${\Delta}_{4,14,1}(z)$ and ${\Delta}_{4,14,2}(z)$ (given in [10, 14]) as linear combinations of eta quotients.