• Korean Chemical Engineering Research
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• v.56 no.6
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• pp.832-840
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• 2018

In this study, both of the concentration of benzo(a)pyrene in 5 species (total 50 samples) of medicinal herbs and their transfer ratios in the preparation steps of water extract(decoction) and soft extract, were measured by HPLC/FLD. The calibration curve of benzo(a)pyrene shows excellent correlation over the concentration range of 3~40 ng/mL with the correlation coefficient ($R^2$) of 1.000. The detected benzo(a)pyrene concentrations from the medicinal herbs ranged from non-detection to $37.54{\mu}g/kg$, and their average was $6.73{\mu}g/kg$. Among the total samples, 15 samples (i.e., 30%) exceeded the limit of herbal medicine benzo(a)pyrene criteria (i.e., $5{\mu}g/kg$) according to the notification No. 2009-302 from Ministry of Food and Drug Safety. In particular, the concentration of benzo(a)pyrene in Coptidis Rhizome was turned out to be the highest of $37.54{\mu}g/kg$. The detected benzo(a)pyrene concentrations from water extract(decoction), soft extract and remnant after boiling, ranged from non-detection to $2.31{\mu}g/kg$, non-detection to $2.28{\mu}g/kg$, and 2.18 to $21.91{\mu}g/kg$, respectively. In preparation of water extract(decoction) and soft extract, transferred benzo(a)pyrene was not detected or, if transferred, the maximal transfer ratios of benzo(a)pyrene were shown to be 8.9% and 9.8%, respectively. Therefore, the content of benzo(a)pyrene in the samples of herbal medicine used in this study, were reduced by more than 90% in preparation steps of water extract (decoction) and soft extract.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.592-602
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• 2020

This study examined the contribution of the risk factors that cause cardiovascular disease in Koreans. The subjects were 20,012 adults aged 30~74 years who were enrolled from the 2005~2013 Korean National Health and Nutrition Examination Survey, had filled the risk factors data, and had no cardiovascular disease history. Data analysis was conducted using SAS 9.3, and a weighted composite sample design analysis was performed. The contribution was obtained by applying a squared semi-partial correlation. As a result, they were higher in the order of age (63.9%), smoking (17.3%), systolic blood pressure (7.9%), diabetes (6.9%), antihypertensive medication use (3.0%), and BMI (0.9%) in men. In women, the contributions were in the order of age (54.1%), systolic blood pressure (23.5%), diabetes (13.6%), antihypertensive medication use (5.1%), smoking (3.1%), and BMI (0.6%%). According to age bracket analysis, smoking (51.8~33.7%) was the biggest risk factor, followed in order by age (26.6%) in their 30s and systolic blood pressure (17.3~21.0%) in those older than 40 years in men. In women, the systolic blood pressure (56.2~40.5%) was the main contributor to the risk factors, followed by age (24.0%) in their 30s and diabetes (13.6~32.6%) in those older than 40 years. The contribution of the income level was similar. Therefore, to prevent cardiovascular disease, various programs that reflect the contributions of the risk factors should be developed. Moreover, it is recommended to use the results shown in this study as basic data.

• Korean Journal of Optics and Photonics
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• v.10 no.2
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• pp.95-101
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• 1999

We have studied the 1.54$\mu\textrm{m}$ forward and backward stimulated Raman scattering (SRS) and stimulated Brillouin scattering (SRS) for various $CH_4$pressures by 1.06$\mu\textrm{m}$ Q-switched Nd:YAG laser pumping under a repetition rate of Hz in single pass. We obtained that the output of backward SRS was more efficient than that of the forward SRS. The output energy and conversion efficiency of forward and backward SRS were higher than those of SBS since SRS is a steady state, but SBS is a transient state. In a $CH_4$gas uncirculating system, the output energy of the backward SRS and SBS were reduced the about 47% due to a thermal heating of $CH_4$medium in a focusing region for a repetition rate of 5 Hz. But, the output energy of forward SRS was slightly enhanced by about 8.5% due to the increase of the undepleted pump beam in the backward SRS generation. Inthe Raman half resonator using a dichromatic focusing lens, the conversion efficiency of SRS was more than 37% for a input pump laser energy of 40 mJ.

• Journal of Chest Surgery
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• v.52 no.1
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• pp.40-43
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• 2019

Epiphrenic diverticula are known to cause a series of complications. We report the case of a 54-year-old woman who was diagnosed with an epiphrenic diverticulum at a regular checkup in November 2006. Ten years later, she presented with massive hematemesis. Imaging studies revealed an epiphrenic diverticulum measuring 7.8 cm in diameter and a large amount of bleeding inside the diverticulum. Computed tomography showed fistula formation between the diverticulum and the left lower lobe of the lung, leading to the development of a pulmonary abscess. Diverticulectomy and $180^{\circ}$ posterior partial fundoplication were performed transabdominally. The pulmonary abscess was treated with antibiotics alone. She was discharged 16 days after the operation without any complications over 7 months of follow-up.

• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.969-985
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• 2020

This study was conducted on 139 nursing students in their junior year of college in G City from October 29 to November 1, 2018, in order to identify the effects of personality type, academic stress and stress coping methods on college life adjustment. The results of the study showed that there were significant differences in college life adjustment (t=2.54, p=.012) according to gender (t=-3.55, p=.001), satisfaction of major (F=9.38, p<.001), satisfaction of interpersonal relationships (F=12.24, p<.001), and judging or perceiving (JP) among the MBTI preference pairs (t=2.54, p=.012). College life adjustment had a significant negative correlation with academic stress (r=-.56, p<.001). Factors that affected college life adjustment included academic stress (β=-.40, p<.001), satisfaction of interpersonal relationships (β=-.27, p<.001), and gender (β=.22, p=.002), and the explanatory power of these factors was 40.6%. Based on the findings of the study, it is necessary to develop and apply extracurricular programs to help nursing students reduce academic stress and improve their interpersonal relationships so that they can adjust well to college life.

• Journal of Digital Convergence
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• v.19 no.10
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• pp.491-500
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• 2021

The status of breast cancer screening of women at a breast clinic in a small city in Korea-Using medical records Purpose: This study was conducted to investigate breast cancer incidence by age, including those under 40, and to emphasize the importance of early breast cancer screening for young breast cancer patients. Method: The study was designed as a retrospective survey method. We investigated the medical charts of 483 patients diagnosed with breast cancer among 23,200 visitors to local breast clinic from May 1, 2010 to April 30, 2020. Results: The average age of 483 patients was 47.9, with 36% in their 40s and 28.6% under 40. Among the patients, 5.4% had a family history of breast cancer, and 70.8% were pre-menopausal. The most common reason for visiting the clinic was the mass(54.2%). The size of tumors was less than 2cm (56%), followed by 2-5cm (43.4%) and more than 5cm (5.6%). The size of tumors was smaller in the asymptomatic case than in the symptomatic case. In the pathologic results, invasive ductal cancer was the most common at 80.3%. Conclusions: Breast cancer screening program should be activated even for young women under the age of 40. We suggest educating the importance of breast cancer screening, and lowering the age of national breast cancer screening program.

• Journal of the Korean Arthroscopy Society
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• v.7 no.2
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• pp.196-200
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• 2003

Purpose : To evaluate clinical outcomes after anterior cruciate ligament (ACL) reconstruction in middle-aged patients and determine the factors affecting the outcome. Subjects and Methods : Clinical results obtained from 60 cases (60 patients) older than 40 years of age at the time of surgery and 58 cases (58 patients) younger than 40 years of age who underwent ACL reconstruction between August 1988 to January 2002, return to sports activity, and stress radiographs using Telos instrument were compared. Results : The Lysholm knee score was improved from the preoperative score of 54.0 points to the postoperative score of 92.9 in patients older than 40 years of age and was improved from 56.2 points to 92.2 points in patients younger than 40 years of age. Clinical outcome was excellent in 51 cases $(85\%)$ and good in 9 cases $(15\%)$ in patients olde. than 40 years of age and was excellent in 47 cases $(81.0\%)$ and good in 11 cases $(19.0\%)$ in patients younger than 40 years of age. There was a significant difference in the rate of returning to preoperative sports activity between patients older than 40 years of age ($60\%$, 36 cases) and younger than 40 years ($82.8\%$, 48 cases). According to Telos stress radiography, the preoperative difference of 11.2 mm was decreased to the postoperative difference of 3.1 mm in patients older than 40 years of age and the preoperative difference of 10.7 mm was decreased to the postoperative difference of 2.9 mm in patients younger than 40 years of age. Clinical outcome did not show significant correlation with age, gender, surgery method, the presence of additional injury, and the rate of return to sports activity before receiving injury (p>0.05). Conclusion : Age didn't have a significant influence on the final outcome of ACL reconstruction and good results could be obtained with ACL reconstruction even in middle-aged patients.

• Clinical and Experimental Reproductive Medicine
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• v.40 no.2
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• pp.47-54
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• 2013

To overcome the difficulty of controlling stem cell fate and function in applications to regenerative medicine, a number of alternative approaches have been made. Recent reports demonstrate that a non-cellular niche modulating the biophysical microenvironment with chemical factors can support stem cell self-renewal. In our previous studies, early establishment was executed to optimize biophysical factors and it was subsequently found that the microgeometry of the extracellular matrix made huge differences in stem cell behavior and phenotype. We review here a three-dimensional, non-cellular niche designed to support stem cell self-renewal. The characteristics of stem cells under the designed system are further discussed.

• Korean Journal of Food Science and Technology
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• v.50 no.3
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• pp.260-266
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• 2018

The change in physicochemical characteristics of sorghum among different varieties and at different harvest stages after heading were evaluated. The proximate compositions and chromaticity of sorghum were significantly different, depending on their varieties and harvesting times. Water solubility was high in sorghum harvested on the $50^{th}$ day after heading; however, the swelling power was reversed. Total polyphenol content of Hwanggeumchal, Nampungchal, and Sodamchal was 17.60-24.62, 17.88-24.67, and 17.37-22.37 mg GAE/g, respectively, and the flavonoid content was 10.43-13.50, 9.68-13.85, and 9.52-12.46 mg CE/g, respectively. The DPPH radical-scavenging activities were 9.94-16.21, 11.42-16.54, and 10.12-15.16 mg TE/g, respectively, and the ABTS radical-scavenging activities were 8.85-19.99, 10.51-20.24, and 9.71-17.93 mg TE/g, respectively. Total polyphenol and flavonoid contents, and radical scavenging activities were high in sorghum harvested on the $40-50^{th}$ day after heading. As a result, it is considered that sorghum varieties such as Hwanggeumchal, Nampungchal, and Sodamchal should be harvested on the $40^{th}$ day after heading.

• Fashion & Textile Research Journal
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• v.21 no.6
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• pp.821-829
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• 2019

This study investigated the location of grading lines and grading amount for a jacket item by the target age groups (20-30, 30-40, and 40-50) for 17 women's wear brands. This study then utilized 7th SizeKorea data to analyze the increase rate of body size and to suggest the grading deviation distribution ratio of the jackets using regression analysis. The increase in neck girth of the jackets targeting aged 30-40s did not reflect the human body change rate. The shoulder length increased by 4.6%-8.1% with the bust girth increase; however, the brands produced longer shoulder length reflecting 20-35% of the bust girth increase. The armhole girth was 54.9% - 59.7% of bust circumstance increase rate. However, the 20-30 target age group brands distributed 80% of bust girth to armhole girth and the 30-40 and the 40-50 target age group brands distributed 50% of the bust girth to armhole. In particular, the 20-30 target age group brands were found to produce a large margin around the armhole. When it came to length items, the brands targeting 20-30s and the 40-50s reflected deviation distribution rate of length from underarm to waist and length from waist to hip in comparison with the overall jacket length deviation. The 30-40 target age group brands, 8 out of 20 brands distributed the jacket length deviation in the length from the back of neck to the underarm; consequently, only 22% percent should be distributed in this part.