• Korean Journal of Pharmacognosy
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• v.17 no.2
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• pp.139-147
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• 1986

Ginseng saponins(GS), protopanaxadiol saponins(PD) and protopanaxatriol saponins (PT) were tested for the inhibition of the development of morphine tolerance and dependence antagonism of morphine analgesia and the loss of morphine tolerance and dependence in mice The results were as follows: 1. Inhibition of the development of morphine tolerance and dependence. 2. Antagonism of morphine analgesia. 3. Increase in the loss of morphine tolerance and dependence. Antagonism of morphine by ginseng saponins and its reversal by L-DOPA and 5-HTP suggest some possibility that catecholamines and serotonin levels might be associated with the results.

• Journal of Ginseng Research
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• v.16 no.2
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• pp.93-98
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• 1992

This study examined the Influence of ginseng total saponins (GTS) on the analgestic action and tolerance development of pentazocine in mice. Pentazocine prolonged the latency to response in the tail flick rather than in the tail pinch test. The analgesic effect of pentaEocine was antagonized by naloxone and completely eliminated by pretreatment u·ith f-chlorophenylalanine (PCPA). GTS provented the pentasocine-incuced analgesia ann inhibited the development of tolerance to pentazocine. The antagonistic effect of GTS on the pentazocine-induced analgesia was abolished by 5-HTP, but not by L-DOPA. These results suggest that GTS inhibits the analgesic action of pentazocine by the interaction with serotonergic neuron.

• Journal of People, Plants, and Environment
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• v.22 no.4
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• pp.365-373
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• 2019

This study was conducted to determine the effects of horticultural therapy on self-esteem of women with hearing impairment. Ten women with hearing impairment registered in the Mokpo Branch of the Korean Association of the Deaf participated in the horticultural therapy programs (HTP) for self-esteem. The self-esteem scale was used to evaluate the effects of the programs and scores were compared to determine the difference before and after the programs. Self-esteem was improved in all 10 subjects, and its mean value increased with statistical significance from 22.5 points before the programs to 29.8 points after the programs. The programs preferred by women with hearing impairment included 'making a centerpiece using scented candles and flowers', 'packing and planting pot spray chrysanthemum', 'making a topiary', 'planting Hedera helix', and 'planting cyclamen'. Therefore, it was suggested that self-esteem of women with hearing impairment were improved by increasing social and family support, emotional stability, positive feedback, and self-expression through horticultural therapy programs.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.15 no.1
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• pp.61-74
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• 2004

Objectives：This study was performed to introduce a psychoeducational family therapy model for the families of schizophrenic patient and to investigate the effect of this model on the changes in coping style and depressive symptoms of the family members, and in perception of emotional support by families and depressive symptoms of patients. Methods：Nine preschool children, 3-5 years old, experiencing physical injuries caused by attack from a psychotic patient at kindergarten, were evaluated for psychological assessments；Intelligence test, MSSB(MacArthur Story-Stem Battery), H-T-P test(House-Tree-Person test). And their parents completed rating scale, KPI-C(Korean Personality Inventory for Children about children’s psychological conditions). Results：With respects to the contents and emotional reactions of MSSB, 9 preschool children showed generally high levels of anxiety, depression, avoidance, aggression, probably related to the traumatic experiences. Even though children couldn't verbally report directly about their traumatic experiences, in both MSSB, structured play narrative assessment tool, and HPT, free drawing and association test, they demonstrated psychiatric problems through reenactment plays, regardless of clinical diagnoses. Conclusion：Present study allowed us the chance to see beyond the outer pathological behaviors of PTSD in preschool children, through deeper evaluations of their mental representation. These preliminary data suggest deep understanding of internal representation would be of help for thorough evaluations and treatment plan for preschool children, experiencing severe trauma.

• Journal of Microbiology and Biotechnology
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• v.12 no.6
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• pp.972-978
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• 2002

Streptomyces sp. AD001 is a Gram-positive soil actinomycetes secreting an uncharacterized 2,4-dichlorophenol (DCP) oxidizing enzyme, whose activity is similar to the previously known Actinomycetes lignin-peroxidase (ALiP). This extracellular peroxidase was purified from Streptomyces sp. AD001 as a single protein band on an SDS-PACE by ammonium sulfate fractionation, Q-sepharose, concanavalin A, and Bio-Gel HTP column chromatographies. The molecular mass of the purified peroxidase was determined by SDS-PAGE to be 45.2 kDa, and 49.7 kDa with MALDI-TOF-MS, respectively. The highest level of peroxidase activity was observed at pH 7.5 and $30^{\circ}C$. The amino terminal sequence of the purified peroxidase (G-E-P-E-E-G-N-V-D-G-T-L) showed no significant homologies to my known proteins, suggesting that Streptomyces sp. AD001 may secrete a novel kind of bacterial peroxidase Initial rate kinetic data of the 2,4-DCP oxidation were best modeled with a random-binding bireactant system.

• Journal of Digital Convergence
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• v.18 no.4
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• pp.201-209
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• 2020

In this paper, we perform a case study of children's emotional care program that analyzes the emotional status through the drawings of children based on web system. In order to overcome spatial and temporal environment constraints, we have developed based on web system that performs to support the whole process from the request of analysis of children 's drawings to the feedback of the final result step by step. The online platform is designed to conduct observations for the purpose of primary screening using a smartphone, and then proceed to the offline secondary care linkage process based on the results. Then according to the results of the analysis, children and parents who need deep examination are figured out and professional institutions are linked to them for help. Parental stress had been analyzed to improve the accuracy of the test and to figure out the cause of the problem. The study was conducted on 2,532 children and their parents between the ages of 3 and 5 years attending a day care center. As a result, 564 children and 223 parents were figured out to be in need of secondary institutional care, and 311 parents were educated and counseled from the professional institutions.

• Journal of KIISE:Computing Practices and Letters
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• v.10 no.6
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• pp.460-471
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• 2004

Since the RTP is suitable for real-time data transmission in multimedia services like VoD, AoD, and VoIP, it has been adopted as a real-time transport protocol by RTSP, H.323, and SIP. Even though the RTP protocol stack for embedded systems has been in great need for efficient support of multimedia services, such a stack has not been developed yet. In this paper, we explain embeddedRTP which supports the RTP protocol stack at the kernel level so that it is suitable for embedded systems. Since embeddedRTP is designed to reside in the UBP module, existing applications which rely ell TCP/IP services can proceed the same as before, while applications which rely on the RTP protocol stack can request HTP services through embeddedRTp API. EmbeddedRTP stores transmitted RTP packets into per session packet buffer, using the packet's port number and multimedia session information. Communications between applications and embeddedRTP is performed through system calls and signal mechanisms. Additionally, embeddedRTP API makes it possible to develop applications more conveniently. Our performance test shows that packet-processing speed of embeddedRTP is about 7.5 times faster than that oi VCL RTP for multimedia streaming services on PDA in spite that its object code size is reduced about by 58% with respect to UCL RTP's.

• Journal of Life Science
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• v.33 no.8
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• pp.639-650
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• 2023

The levels of harmful components in aerosols from heated tobacco products (HTPs) have been reported to be significantly lower than in cigarette smoke. However, it remains unclear whether the use of HTPs can mitigate the cardiovascular risks associated with cigarette smoking (CS). The objective of this study was to investigate the effects of a short-term switch from CS to HTP use on cardiac autonomic regulation (CAR). Seven healthy male smokers completed an open-label, randomized, cross-over trial consisting of five days of CS, use of three different HTPs (IQOS use, IQ; lil SOLID use, LS; lil HYBRID use, LH), or non-smoking (NS). Each session was separated by a one-week washout period, and levels of exhaled carbon monoxide (CO) and carboxyhemoglobin (COHb), systolic (SBP) and diastolic blood pressure (DBP), and heart rate variability (HRV) reflecting CAR were assessed before use of the product assigned to each session and at 24, 48, 72, 96, and 120 hr after use. Levels of exhaled CO and COHb were statistically significantly reduced only during NS. There were no statistical changes in SBP and DBP within any session. However, in HRV spectral analysis, log-transformed high frequency (lnHF) increased statistically significantly in IQ, LS, and NS, respectively. Normalized HF (HFnu) was significantly increased in NS and LH, respectively. lnHF and HFnu showed significant interaction effects. The findings of this study suggest that a short-term switch to HTPs instead of CS may lead to different distribution patterns of CAR, primarily driven by enhanced cardiac vagal tone.

• Journal of The Korean Society of Grassland and Forage Science
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• v.43 no.4
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• pp.206-215
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• 2023

This study was performed to investigate immune changes by comparing the proportion and function of immune cells in the blood under high-temperature period and convalescence temperature period in Holstein dairy cows. The experiment was conducted using Holstein dairy cows of five animals per group (60 ± 20 months old, 175 ± 78 non-day) from the National Institute of Animal Science at high-temperature period (THI: 76 ± 1.2) and convalescence temperature period (THI: 66 ± 1.3). Complete blood count results showed no change in the number of immune cells between groups. In the analysis using Flow Cytometry of PBMCs, no significant differences were observed among B cells, Helper T cells, cytotoxic T cells, and γδ T cells between groups. However, there was an increase in Th17 cells producing IL-17a, while Th1 cells decreased during the convalescence temperature period. The results of gene expression analysis using qRT-PCR in PBMCs revealed an increase in IL-10 during the convalescence temperature period, while a decrease in HSP70 and HSP90 was observed. In conclusion, the increased expression of IL-10 and the decrease in HSP expression suggest the possibility of a weak recovery from heat stress. However, the lack of observed changes in B cells, T cells, and other immune cells indicates incomplete recovery from heat stress during the convalescence temperature period.