• 제목/요약/키워드: 5-FU

검색결과 723건 처리시간 0.023초

Study on rectangular concrete-filled steel tubes with unequal wall thickness

  • Zhang, Yang;Yu, Chen-Jiang;Fu, Guang-Yuan;Chen, Bing;Zhao, She-Xu;Li, Si-Ping
    • Steel and Composite Structures
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    • 제22권5호
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    • pp.1073-1084
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    • 2016
  • Rectangular concrete-filled steel tubular columns with unequal wall thickness were investigated in the paper. The physical centroid, the centroidal principal axes of inertia, and the section core were given. The generalized bending formula and the generalized eccentric compression formula were deduced, and the equation of the neutral axis was also provided. The two rectangular concrete-filled steel tubular stub specimens subjected to the compression load on the physical centroid and the geometric centroid respectively were tested to verify the theoretical formulas.

Fabrication of Composite Drug Delivery System Using Nano Composite Deposition System and in vivo Characterization

  • Chu, Won-Shik;Jeong, Suk-Yong;Pandey, Jitendra Kumar;Ahn, Sung-Hoon;Lee, Jae-Hoon;Chi, Sang-Cheol
    • International Journal of Precision Engineering and Manufacturing
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    • 제9권2호
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    • pp.81-83
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    • 2008
  • The Rapid Prototyping (RP) technology has advanced in many application areas. In this research, two different types, cylinder and scaffold, of implantable Drug Delivery System (DDS) were fabricated using Nano Composite Deposition System (NCDS), one of the RP systems. The anti-cancer drug (5-fluorouracil, 5-FU), biodegradable polymer (PLGA(85: 15)), and bio ceramic (Hydroxyapatite, HA) were used to form drug-polymer composite material. Both types of DDS were evaluated in vivo environment for two weeks. For evaluation, the cumulative drug release and shape stability were measured. Test results showed that the scaffold DDS provide higher cumulative drug release and has better stability than cylinder DDS.

DRYING CHARACTERISTICS OF RANGOLA GRASS

  • Lu, Fu-ming;Kung, Hsiang-chin
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 1996년도 International Conference on Agricultural Machinery Engineering Proceedings
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    • pp.886-895
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    • 1996
  • To fit the desorption isotherm and adsorption isotherm for Pangola grass, the modified Henderson model, Chung-Pfost model, modified Halsey model, and modified Oswin model were used to fit the experimental EMC /ERH data. A step-by -step ERH measuring technique was used in this study. The ERH data were collected at three temperature levels of 5 $^{\circ}C$, $25^{\circ}C$ and 5$0^{\circ}C$ for Pangola grass whole plant, stem , and foliage. The modified Halsey model has the best fit for both desorption isotherm and adsorption isotherm of Pangola grass whole plant as compared with other models.

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Sliding Mode Control of Three-Phase Four-Leg Inverters via State Feedback

  • Yang, Long-Yue;Liu, Jian-Hua;Wang, Chong-Lin;Du, Gui-Fu
    • Journal of Power Electronics
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    • 제14권5호
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    • pp.1028-1037
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    • 2014
  • To optimize controller design and improve static and dynamic performances of three-phase four-leg inverter systems, a compound control method that combines state feedback and quasi-sliding mode variable structure control is proposed. The linear coordinate change matrix and the state variable feedback equations are derived based on the mathematical model of three-phase four-leg inverters. Based on system relative degrees, sliding surfaces and quasi-sliding mode controllers are designed for converted linear systems. This control method exhibits the advantages of both state feedback and sliding mode control. The proposed controllers provide flexible dynamic control response and excellent stable control performance with chattering suppression. The feasibility of the proposed strategy is verified by conducting simulations and experiments.

Interaction of Indigo Carmine with Cetyltrimethylammonium Bromide and Application to Determination of Cationic Surfactant in Wastewater

  • Wang, Hong-Yan;Gao, Hong-Wen;Zhao, Jian-Fu
    • Bulletin of the Korean Chemical Society
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    • 제24권10호
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    • pp.1444-1448
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    • 2003
  • The microsurface adsorption - spectral correction (MSASC) technique has been applied to the interaction of indigo carmine (IC) with cetyltrimethylammonium bromide (CTAB). The aggregation of IC on CTAB obeys Langmuir isothermal adsorption. The results show that both the monomer complex $IC{\cdot}CTAB$ and the micellar complex $(IC{\cdot}CTAB)_{78}$ were formed. The binding constant of the monomer complex was calculated to be $K_{IC{\cdot}CTAB}$ = 2.20 ${\times}10^5L{\cdot}mol^{-1}$, and the molar absorptivity of the micellar complex was calculated to be ${\varepsilon}_{(IC{\cdot}CTAB)78}\;^{560nm}$ = 8.58 ${\times}10^5L{\cdot}mol^{-1}{\cdot}cm^{-1}$. The aggregation was applied to the determination of cationic surfactant in wastewater.

Analytical solutions for skewed thick plates subjected to transverse loading

  • Chun, Pang-Jo;Fu, Gongkang;Lim, Yun Mook
    • Structural Engineering and Mechanics
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    • 제38권5호
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    • pp.549-571
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    • 2011
  • This paper presents analytical solutions for skewed thick plates under transverse loading that have previously been unreported in the literature. The thick plate solution is obtained in a framework of an oblique coordinate system. The governing equation is first derived in the oblique coordinate system, and the solution is obtained using deflection and rotation as partial derivatives of a potential function developed in this research. The solution technique is applied to three illustrative application examples, and the results are compared with numerical solutions in the literature and those derived from the commercial finite element analysis package ANSYS 11. These results are in excellent agreement. The present solution may also be used to model skewed structures such as skewed bridges, to facilitate efficient routine design or evaluation analyses, and to form special elements for finite element analysis. At the same time, the analytical solution developed in this research could be used to develop methods to address post-buckling and dynamic problems.

Non-linear static analysis and design of Tensegrity domes

  • Fu, Feng
    • Steel and Composite Structures
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    • 제6권5호
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    • pp.417-433
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    • 2006
  • In this paper, a non-linear structural analysis software with pro-processing and post-recessing function is proposed by the author. The software incorporating the functions of the structural analysis and geometrical design of Tensegrity structures. Using this software, Cable Dome is analyzed as a prototype, a comprehensive study on the structural behavior of Tensegrity domes is presented in detail. Design methods of Tensegrity domes were proposed. Based on the analysis, optimizing design was performed. Several new Tensegrity domes with different geometrical design scheme are proposed, the structural analysis of the new schemes is also conducted. The analysis result shows that the proposed new forms of the Tensegrity domes are reasonable for practical applications.

Inhibitory Lignans against NFAT Transcription Factor from Acanthopanax koreanum

  • Cai, Xing-Fu;Lee, Im-Seon;Dat, Nguyen-Tien;Guanghai-Shen;Kang, Jong-Seong;Kim, Dong-Hyun;Kim, Young-Ho
    • Archives of Pharmacal Research
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    • 제27권7호
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    • pp.738-741
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    • 2004
  • Three lignans isolated from the roots of A. koreanum (Araliaceae), namely eleutheroside E(1), tortoside A(2), and hemiariensin(4), were evaluated for their ability to inhibit NFAT transcription factor. Of these compounds, compound 4, possessing a diarylbutane skeleton, exhibited potent inhibitory activity against NFAT transcription factor (($IC_{50}$ : 36.3${\pm}2.5{\mu}\textrm{M}$). However, the activities of 1 (($IC_{50}$:>500 11M) and 2 (($IC_{50}$: 136.1 ${\pm}9.4\mu\textrm{M}$), which possess bisaryldioxabicy-clooctane skeletons, were lower. As the lignan derivatives of the same skeletons, hinokinin (5) and (-)-yatein (6) with diarylbutane skeletons and(+)-syringaresinol (3) with a bisaryldioxabicy-clooctane skeleton were also studied for their inhibitory effects on NFAT transcription factor.

Concrete strength monitoring based on the variation of ultrasonic waveform acquired by piezoelectric aggregates

  • Wei, Li;Wang, Zijian;Cao, Maosen;Fu, Ronghua
    • Structural Engineering and Mechanics
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    • 제76권5호
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    • pp.591-598
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    • 2020
  • Ultrasonic waves provide a non-destructive and sensitive way to monitor the concrete hydration. However, limited works are reported to monitor the evolution of the mechanical parameter at early ages. In this study, modified piezoelectric aggregates are embedded inside a concrete beam to excite and receive primary waves. A hydration index, namely, the variation of ultrasonic waveform (VUW) is developed to characterize the variation of the transmitted waves during the hydration process. The recorded hydration indices are compared with the compressive strength measured by destructive test at different ages. The results show that the VUW is closer to the compressive strength than the other two traditional hydration indices, ultrasonic velocity and wave packet energy. The proposed VUW provides a simple and accurate way to monitor the concrete hydration at early ages.

THE BIPOLAR SMOULDER PROSTHESIS LONGER TERM RESULTS (5-10 YEARS) IN THE MANAGEMENT OF END-STAGE ROTATOR CUFF ARTHROPATHY

  • M.B.B.S. Prue Keith;Worland Richard L.
    • 대한견주관절학회:학술대회논문집
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    • 대한견주관절학회 2002년도 아시아견관절학술대회
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    • pp.11-19
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    • 2002
  • This prospective clinical study evaluates the 5-10 year results of the BiPolar shoulder Arthroplasty in patients with end-stage RotatorCuff Arthropathy. The study group consisted of 48 patients (59 shoulders). Average age was 72 years and average FU time was 73 months. Results showed that the average UCLA score went from 7.9 Pre-op to 23.3 Post-op. Final Constant score averaged $52\% (unadjusted). Pain relief using the VAS was 1.2(were 0=no pain. 15 = excruciating pain). ROM improved by an average of $20^\circ$. There were 2 reoperations because of periprosthetic fractures. Despite rather poor functional results, these patients were satisfied with their pain relief and the functional gains accompanying pain relief would be an added benefit.

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