• Title/Summary/Keyword: 5'-Modification

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Dynamics of Nanopore on the Apex of the Pyramid

  • Choi, Seong-Soo;Yamaguchi, Tokuro;Park, Myoung-Jin;Kim, Sung-In;Kim, Kyung-Jin;Kim, Kun-Ho
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.187-187
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    • 2012
  • In this report, the plasmonic nanopores of less than 5 nm diameter were fabricated on the apex of the pyramidal cavity array. The metallic pyramidal pit cavity can also utilized as the plasmonic bioreactor, and the fabricated Au or Al metallic nanopore can provide the controllable translocation speed down using the plasmonic optical force. Initially, the SiO2 nanopore on the pyramidal pit cavity were fabricated using conventional microfabrication techniques. Then, the metallic thin film was sputter-deposited, followed by surface modification of the nanometer thick membrane using FESEM, TEM and EPMA. The huge electron intensity of FESEM with ~microsecond scan speed can provide the rapid solid phase surface transformation. However, the moderate electron beam intensity from the normal TEM without high speed scanning can only provide the liquid phase surface modification. After metal deposition, the 100 nm diameter aperture using FIB beam drilling was obtained in order to obtain the uniform nano-aperture. Then, the nanometer size aperture was reduced down to ~50 nm using electron beam surface modification using high speed scanning FESEM. The followed EPMA electron beam exposure without high speed scanning presents the reduction of the nanosize aperture down to 10 nm. During these processes, the widening or the shrinking of the nanometer pore was observed depending upon the electron beam intensity. Finally, using 200 keV TEM, the diameter of the nanopore was successively down from 10 nm down to 1.5 nm.

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The Awareness of Cardiovascular Risk Factors and Its Correlates in Patients with Coronary Artery Diseases (관상동맥질환자의 위험요인 인식 및 관련요인)

  • Yang, In-Suk;Choi, Dong-Hoon;Kang, Youn-Hee
    • Korean Journal of Adult Nursing
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    • v.22 no.5
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    • pp.499-508
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    • 2010
  • Purpose: Cardiovascular risk factor modification is important for patients with coronary artery disease to prevent poor progression of the disease. Without an understanding and an awareness of risk factors, patients with coronary artery disease are not able to reduce their risk by the lifestyle modification. The aims of this study were to assess patient's awareness of risk factors and to identify predictors of awareness of risk factors. Methods: A descriptive correlational study using a cross-sectional survey method was performed. The sites of the study were three hospitals in Seoul, Korea. The sample consisted of 214 subjects. The awareness of risk factors and other subjects' characteristics were measured by a questionnaire developed for this study. Results: A range of subjects (gender: 72.0%; hyperlipidemia: 51.9%; hypertension: 40.7%; obese: 37.4%; age: 35.5%; smoking: 22.4%; diabetes: 19.2%; family history: 18.2%) were not able to accurately identify the risk factors. Among predictors, gender (${\beta}$=-.17) and diabetics (${\beta}$=-.25) had statistically significant influences on awareness of risk factors. Conclusion: Our findings highlight the lack of awareness of risk factors for coronary artery disease. The findings have important implications for nursing practice in terms of guiding educational strategies for the modification of risk factors for coronary heart disease.

Surface Modification of Flake-Shaped Inorganic Mica and Their Cool Paint Performances (판상형 무기소재인 Mica의 표면개질 및 차열페인트의 특성 평가)

  • Park, Jeong Min;Kim, Hee Jung;Yoo, Jung Whan
    • Applied Chemistry for Engineering
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    • v.27 no.1
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    • pp.35-38
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    • 2016
  • In this study, the mica used as a thermal-insulation material was modified with a silane coupling agent, octyltriethoxysilane (OTES), to improve its hydrophobicity. The modified mica was characterized using FT-IR spectrometer, water wettability test, and water contact angle measurement. The analysis exhibits that OTES for the modified mica sample was well bonded chemically and drastically enhanced the hydrophobicity. The reflectance observed as 73.9% (mica) and 86.4% (OTES/mica), respectively, for OTES/mica was improved about 12.5% before any modifications. Also the modified mica sample showed $7.2^{\circ}C$ decrease in the thermal-insulation performance of cool paints compared to that of using unmodified mica, indicating that the modification of mica with silane coupling agents could be effective in enhancing the thermal-insulation performance of the cool paint.

Surface Modification and Heat Treatment of Ti Rod by Electro Discharge (전기방전에 의한 Ti rod의 열처리 및 표면개질 특성에 관한 연구)

  • Byun, C.S.;Oh, N.H.;An, Y.B.;Cheon, Y.W.;Kim, Y.H.;Cho, Y.J.;Lee, C.M.;Lee, W.H.
    • Korean Journal of Materials Research
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    • v.16 no.3
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    • pp.168-172
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    • 2006
  • Single pulse of 2.0 to 3.5 kJ from $150{\mu}F$ capacitor was applied to the cp Ti rod for its surface modification and heat treatment. Under the conditions of using 2.0 and 2.5 kJ of input energy, no phase transformation has been occurred. However, the hardness and tensile strength decreased and the elongation increased after a discharge due to a slight grain growth. By using more than 3.0 kJ of input energy, the electro discharge made a phase transformation and the hardness at the edge of the cross section increased significantly. The Ti rod before a discharge was lightly oxidized and was primarily in the form of $TiO_2$. However, the surface of the Ti rod has been instantaneously modified by a discharge into the main form of TiN from $TiO_2$. Therefore, the electro discharge can modify its surface chemistry in times as short as $200{\mu}sec$ by manipulating the input energy, capacitance, and discharging environment.

Generation of Artificial Time History Covering Design Response Spectrum by Two Modification Functions (이중 수정함수 적용을 통한 설계응답스펙트럼 포괄 인공지진파의 생성)

  • Park, Gun;Hong, Ki Nam;Han, Sang Hoon;Kim, Jae Suk
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.1-11
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    • 2016
  • The domestic and foreign seismic design codes have specified that time history covers design response spectrum when the response spectrum, which calculated from the time history, is smaller than the design response spectrum at five points or less. In order to verify the design codes, time history analysis for a pier was performed by using five artificial time histories conforming design code with various characteristics and its member forces were evaluated according to them. It was confirmed from analysis results that, regardless of the conformity to design code requirement, seismic design using the artificial time histories could not guarantee earthquake resistant design if the response spectrum from them is lower than design response spectrum at the similar period to the natural frequency of structure. Thus, the time history generating method to make its acceleration response spectrum to be greater than design response spectrum at all period was proposed by two modification function in this study. It was also verified whether time histories from the proposed method satisfy the seismic design codes or not.

Development of Site Classification System and Modification of Design Response Spectra considering Geotechnical Site Characteristics in Korea (III) - Modification of Desing Response Specra (국내 지반특성에 적합한 지반분류 방법 및 설계응답스펙트럼 개선에 대한 연구 (III) - 설계응답스펙트럼 개선방법)

  • Yoon, Jong-Ku;Kim, Dong-Soo;Bang, Eun-Seok
    • Journal of the Earthquake Engineering Society of Korea
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    • v.10 no.2 s.48
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    • pp.63-71
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    • 2006
  • In the companion paper (II, Development of Site Classification System), new size classification system based on site periods $(T_G)$ was recommended for legions of shallow bedrock depth in Korea. Despite the site classification method was improved, the response spectrum would be required to be modified by adjusting the integration interval to calculate the site coefficients because the response spectra did not match well the average spectral accelerations obtained by site response analyses in the range of long periods. In this paper, new response spectra for each site categories were determined by adjusting the integration interval of long period site coefficient $F_v\;from\;0.4{\sim}2.0\;to\;0.4{\sim}1.5$ second. It matched well the average spectral accelerations and new response spectrum, and it was also improved compared to the current she classification system.

Study on the Improvement of Speech Recognizer by Using Time Scale Modification (시간축 변환을 이용한 음성 인식기의 성능 향상에 관한 연구)

  • 이기승
    • The Journal of the Acoustical Society of Korea
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    • v.23 no.6
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    • pp.462-472
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    • 2004
  • In this paper a method for compensating for thp performance degradation or automatic speech recognition (ASR) is proposed. which is mainly caused by speaking rate variation. Before the new method is proposed. quantitative analysis of the performance of an HMM-based ASR system according to speaking rate is first performed. From this analysis, significant performance degradation was often observed in the rapidly speaking speech signals. A quantitative measure is then introduced, which is able to represent speaking rate. Time scale modification (TSM) is employed to compensate the speaking rate difference between input speech signals and training speech signals. Finally, a method for compensating the performance degradation caused by speaking rate variation is proposed, in which TSM is selectively employed according to speaking rate. By the results from the ASR experiments devised for the 10-digits mobile phone number, it is confirmed that the error rate was reduced by 15.5% when the proposed method is applied to the high speaking rate speech signals.

Investigation of chemical modification on tosyl-activated polystyrene microsphere magnetic particle surface by infrared microscopy (토실 활성화된 폴리스티렌 마이크로구체 자성 입자 표면의 화학적 변형에 대한 적외선 연구)

  • Byun, Chang Kyu
    • Analytical Science and Technology
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    • v.29 no.5
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    • pp.225-233
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    • 2016
  • The chemical engrafting of polymers on particle surface, plays an important role on selective partitioning of micro/nano-particles in the separated layers of liquid media, such as aqueous two phase systems (ATPSs). Three polymers, dextran, poly (ethylene glycol) and albumin were chosen and chemically conjugated to the polystyrene (PS) magnetic microparticle surface. The attachment of long-chained polymer chains which may switch the partition behavior, can be simply performed by SN2 substitution of various polymers having primary amine functional groups, with p-toluenesulfonyl (tosyl)-activated polystyrene magnetic micro-particles. The surface modification of microparticle was probed by infrared microscopy. The distinctive peak represents N-H stretching vibration mode for microparticles after the reaction and it is common for all three polymers examined. The locations of main peaks are similar for all micro-particles but different and distinguishable in fingerprint region.

Modification of nutrition strategy for improvement of postnatal growth in very low birth weight infants

  • Choi, Ah Young;Lee, Yong Wook;Chang, Mea-young
    • Clinical and Experimental Pediatrics
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    • v.59 no.4
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    • pp.165-173
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    • 2016
  • Purpose: To identify the effects of modified parenteral nutrition (PN) and enteral nutrition (EN) regimens on the growth of very low birth weight (VLBW) infants. Methods: The study included VLBW infants weighing <1,500 g, admitted to Chungnam National University Hospital between October 2010 and April 2014, who were alive at the time of discharge. Subjects were divided according to 3 periods: period 1 (n=37); prior to the PN and EN regimen being modified, period 2 (n=50); following the PN-only regimen modification, period 3 (n=37); following both PN and EN regimen modification. The modified PN regimen provided 3 g/kg/day of protein and 1 g/kg/day of lipid on the first day of life. The modified EN regimen provided 3.5-4.5 g/kg/day of protein and 150 kcal/kg/day of energy. We investigated growth rate, anthropometric measurements at 40 weeks postconceptional age (PCA) and the incidence of extrauterine growth restriction (EUGR) at 40 weeks PCA. Results: Across the 3 periods, clinical characteristics, including gestational age, anthropometric measurements at birth, multiple births, sex, Apgar score, surfactant use and PDA treatment, were similar. Growth rates for weight and height, from time of full enteral feeding to 40 weeks PCA, were higher in period 3. Anthropometric measurements at 40 weeks PCA were greatest in period 3. Incidence of weight, height and head circumference EUGR at 40 weeks PCA decreased in period 3. Conclusion: Beginning PN earlier, with a greater supply of protein and energy during PN and EN, is advantageous for postnatal growth in VLBW infants.

Effects of Surface-modification of Carbon Black on the Characteristics of Polymerized Toner (카본블랙의 표면개질이 중합토너의 특성에 미치는 영향)

  • Lee, Eun Ho;Kim, Dae Su
    • Korean Chemical Engineering Research
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    • v.51 no.5
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    • pp.628-633
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    • 2013
  • Carbon black was surface-modified to prepare styrene-based suspension polymerized toner with excellent carbon black dispersibility inside toner particles. Carbon black was oxidized first to introduce hydroxyl groups on the surfaces, then esterification between the hydroxyl groups and carboxyl groups of organic acids (oleic acid, palmitic acid, acrylic acid) was followed to obtain organically surface-modified carbon black. The surface-modification of carbon black was confirmed by FTIR. Apparent carbon black dispersibility in the monomer mixture of the binder resin was tested and the particle size of dispersed carbon black was measured by particle size analyzer. Optical micrographs showed that carbon black dispersibility inside toner particles was improved considerably when the carbon black surfacemodified with oleic acid was used. The polymerized toner prepared with the carbon black surface-modified with oleic acid showed ideal particle size and size distribution as a toner.