• 제목/요약/키워드: 4P Analysis

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두 개의 플랫폼을 가지는 새로운 타입의 공간 4 자유도 병력기구의 조합 및해석 (Synthesis and Analysis of a New Class of Spatial4-DOF Parallel Mechanism with Two Platforms)

  • 윤정원;류제하
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 추계학술대회
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    • pp.1482-1487
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    • 2003
  • This paper presents a new family of 4-DoF parallel mechanism with two platforms. The new mechanism is composed of front and rear platforms, and three limbs. Two limbs with 6dof joint (P-P-S-P) are attached to the each platform and are perpendicular to baseplate, while the middle limb with 4-Dof joints (R-R-R-P or R-R-P-P) is attached to the revolute joint that connect front and rear platform. The two-DoF-driving mechanism at the middle limb with two base-fixed prismatic actuators can generate the heaving and roll motions or two translational motions. Therefore, Therefore, the new 4-Dof parallel mechanism (1T-3R) can generate pitch motions at each platforms, roll, and heaving motions, while another type of new 4-Dof parallel mechanism (2T-2R) can generate pitch motions at each platforms, x and z translational motions. For 1T-3R mechanism, kinematic analyses including inverse, forward kinematics, and Jacobian are performed.

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Southern Hybridization에 의한 Biphenyl 및 4-Chlorobiphenyl 분해유전자들의 상동성 분석 (Homology Analysis Among the Biphenyl and 4-Chlorobiphenyl Degrading Genes by Southern Hybridization)

  • 남정현;김치경;이재구;이길재
    • 한국미생물·생명공학회지
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    • 제22권1호
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    • pp.37-44
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    • 1994
  • The homology among the genes coding for degradation of bipheny(BP) and 4-chlorobiphenyl(4CB) was comparatively analyzed by Southern hybridization in several BP/4CB degrading bacterial strains. As the hybridization results of their genomic DNAs with pcbABCD as the DNA probe, the group of Pseudomonas sp. DJ-12. P08 and P27 strain was separated by the group of P20 and P1242 strains. The P. pseudoalcaligenes KF707 showed the hybidization signal which was homologous to the group of DJ-12, but they had different restriction endonuclease sites. The pcbAB genes in pCUl recombinant plasmid from Pseudomonas sp. DJ-12 appeared to be homologous to pchAB genes in pKTF20 cloned from P. pseudoalcaligenes KF707, but the C genes in both strains were not homologous. The bphABC in pKTF20 showed the signals homologous to the cbp ACB in pAW6194 cloned from P. putida OU83, but homologous signal was not found botween the pcbABCD genes in pCUl and the cbpADCB genes in pAW6194 recombbinant plasmid.

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Impact of Methylation of the Gene $p16^{INK4a}$ on Prognosis of Head and Neck Osteosarcoma

  • Kim, Yong-Deok;Hwang, Dae-Seok;Kim, Cheol-Hoon;Shin, Sang-Hun;Kim, Uk-Kyu;Kim, Jong-Ryoul;Chung, In-Kyo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제33권1호
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    • pp.46-54
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    • 2007
  • PURPOSE Osteosarcoma occurring in the head and neck region is known as a malignant tumor that shows a relatively poor prognosis and, despite various treatments, clinicians have often been confounded by it. The existence or non-existence of the mutation of the gene $p16^{INK4a}$ has been used in prognosis assessment. In this study, author have attempted to determine whether methylation of the gene $p16^{INK4a}$ could be applied to forecast the progress of osteosarcomas in the head and neck region having been given poor prognoses in the diagnostic process and the early stage of treatment. RESEARCH SUBJECT AND METHOD Clinicopathologic investigations, immunohistochemical examinations, a methylation specific polymerase reaction (MSP) analysis, and a survival analysis were conducted on the tissues of 20 patients with mandibulofacial osteosarcoma. RESULTS Neither age, sex, size, smoking or non-smoking, nor region have showed a statistical significance with methylation or unmethylation of the gene $p16^{INK4a}$ and expression rates demonstrated by immunohisto- chemical examinations. A chi-square test indicated that recurrence inclination has no relation with the expression rate of p16 protein (p=0.6615), but it showed a statistical significance with methylation of the gene $p16^{INK4a}$ (p=0.0033). With respect to investigations of the survival rates, a Kaplan-Meier survival analysis found that the manifestation rate of p16 protein did not have an impact on survival (p=0.8864), but that the methylation of the gene $p16^{INK4a}$ resulted in significant differences in survival rates (p=0.0105). CONCLUSIONS The above results show that methylation of the gene $p16^{INK4a}$ could be one of the major factors that help determine the recurrence inclination and prognosis of osteosarcomas occurring in the head and neck region.

적외선 분광 분석과 조직 분석을 통한 출토 인골의 보존 상태 평가 (Conservation status assessment of archaeological bone from Fourier Transform Infrared Spectroscopy and histological Analysis)

  • 이정원;김수훈;김윤지;조은민;강소영
    • 보존과학연구
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    • 통권35호
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    • pp.87-98
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    • 2014
  • 뼈의 보존 상태를 화학적으로 평가하기 위하여 조선시대 인골 10점을 대상으로 감쇠전반사법을 활용한 적외선 분광분석(FTIR-ATR)을 실시하였다. FTIR-ATR 스펙트럼을 통해 결정화 지수(crystallinity index; CI), 탄산염간의 비(C/C), 탄산염과 인산염의 비(C/P)를 계산한 결과 CI는 $4.25{\pm}0.78$, C/C는 $0.91{\pm}0.04$, C/P 는 $0.19{\pm}0.06$으로 확인되었다. 화학적 평가 결과 조직학 지수가 높을수록 CI와 C/P 값이 증가하며, C/C는 감소하는 것을 확인하였다. 반면 뼈에서 추출한 DNA 분석 가능 여부는 C/C가 낮고 C/P가 높을수록 분석이 가능 하였다. 이를 통해 FTIR을 이용한 화학적 평가와 조직 분석 결과가 출토 인골의 보존 상태를 종합적으로 파악하기 위한 기준으로 적용이 가능할 것으로 판단된다.

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간호사의 수면장애, 조직 내 지지, 건강증진행위가 소진에 미치는 영향 (The Influence of Clinical Nurses' Sleep Disorder, Organizational Support, Health promotion behaviors on Burn-out)

  • 장진숙;김미영
    • 문화기술의 융합
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    • 제7권2호
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    • pp.27-33
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    • 2021
  • 본 연구는 간호사의 수면장애, 조직 내지지, 건강증진행위가 소진에 미치는 영향을 파악하기 위해 시도된 서술적 상관관계연구이다. 연구대상자는 B와 G시에 소재한 200병상 이상 300병상 미만 병원에서 근무 중인 간호사 256명을 대상으로 하였다. 자료 수집은 2017년 9월 4일부터 9월 11일까지 이며, 수집된 자료는 SPSS WIN 20.0을 이용하여 분석하였다. 소진은 평균 28.90±4.00점이며, 소진은 수면장애(r=-.321, p<.001), 조직 내 지지(r=-.321, p<.001), 건강증진행위(r=-.519, p<.001), 소진에 미치는 영향요인은 조직 내 지지(β=-.113, p=.045), 수면장애(β=-.129, p<.040), 성별(β=-.131, p=.024), 건강증진행위(β=-.423, p<.001)이며, 설명력은 32.2%이었다. 간호사의 소진을 조절할 수 있는 각종 프로그램 개발이 필요하다.

포괄치위생관리(CDHC) 과정 적용에 따른 스케일링 경험 대상자의 구강건강신념과 만족도 (Oral health belief and satisfaction after scaling experience with comprehensive dental hygiene care)

  • Kim, Mi-Hye;Moon, Sang-Eun;Kim, Yun-Jeong;Kim, Seon-Yeong;Cho, Hye-Eun;Kang, Hyun-Joo
    • 한국치위생학회지
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    • 제22권1호
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    • pp.1-9
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    • 2022
  • 연구목적: 본 연구는 포괄치위생관리(Comprehensive Dental Hygiene Care; CDHC) 과정 적용에 따른 스케일링 경험 대상자의 구강건강신념과 만족도를 확인하고자 수행하였다. 연구방법: 2020년 7월 1일부터 2020년 9월 20일까지 치과 병·의원에서 스케일링을 받은 대상자 182명의 자료를 수집하여 분석하였다. 자료는 SPSS Statistics 22.0을 이용하여 빈도분석, chi-square, t-test, One way ANOVA, Pearson's correlation analysis를 실시하였다. 연구결과: 구강건강행태는 CDHC 적용 그룹에서 칫솔, 치약 외 구강관리용품 사용 92.4%(p<0.001), 구강관리를 위한 정기적인 치과 방문이 67.4%였다(p<0.001). 일반적 특성에 따른 구강건강신념은 CDHC 적용 그룹에서 연령 '50-65세'가 2.41로 가장 높았고, 사후검정 결과 '20-29세'와 유의한 차이가 있었다(p <0.001). CDHC 적용 그룹에서 구강건강행태에 따른 구강건강신념은 스케일링 주기 '3개월'이 가장 높았다(p<0.05). CDHC 적용 그룹의 구강건강신념 하위 요소인 유익성(p <0.01)과 중요성(p<0.05)이 높을수록 만족도와 높은 상관관계를 보였다. 결론: CDHC 적용이 스케일링 경험 대상자들의 구강건강신념과 만족도에 긍정적인 영향을 주는 것을 알 수 있었다. CDHC 과정 적용은 구강건강신념과 만족도를 높이는 매개로써 임상에 더욱 확산하여야 할 것이다.

학령기 아동의 건강 행위 실천의 예측 요인 (Predicting and Understanding School-Age Children위s Health Behavior)

  • 신희선;정연
    • 대한간호학회지
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    • 제28권4호
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    • pp.846-855
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    • 1998
  • The purpose of the study was to investigate the level of health behavior of school-age children and to identify the predicting variables of the school-age children's health behavior. The subject were 467 children in grades four to six, enrolled in two elementary schools located in two cities. The mean age of the subject was 10.03(SD=1.33). The data were analyzed using t-test, ANOVA, correlation analysis, and stepwise multiple regression. The result are as follows : 1. The mean of the score of health behavior of the school-age children was 154.6, showing that they are practicing health behavior relatively well. 2. There were significant differences in the mean scores of health behavior according to grade (F=6.53 p=.001), sex(t=-3.70, p=.000), educational level of the parents(F=4.92, p=.002 ; F=4.47, p=.004), occupation of the parents(F=3.31, p=.003 ; F=4.76, p=.000), and socioeconomic status(F=11.87, p=.000). 3. There were significant correlations between health behavior and health motivation(r=.53, p=.000), self-concept(r=.32, p=.000), perceived health status(r=.16, p=.000), and health locus of control (r=.15, p=.001). 4. Health motivation, self-concept, grade, socioeconomic status, and health locus of control were identified as predictor variables of health behavior of the school-age children from the stepwise multiple regression analysis. The total percent of variance accounted for by these five variables was 35.0%. From the result, it is suggested that in the development of a school health education program, the effect of health motivation and self-concept to promote student's health behavior in school-age children should be considered.

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학령전기 아동의 스마트폰 과몰입에 영향을 미치는 요인 (Factors associated with Smartphone Overdependency in Preschool Children)

  • 이민정;박성희
    • Child Health Nursing Research
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    • 제24권4호
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    • pp.383-392
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    • 2018
  • Purpose: The purpose of this study was to identify factors associated with smartphone overdependency in preschool children based on an analysis of mother, child, and their mutual dyadic relationships. Methods: Data were collected from 171 mothers of preschool children enrolled at daycare centers and kindergartens from January to March 2018. The data were analyzed by descriptive statistics, the t-test, analysis of variance with $Scheff{\acute{e}}$ post hoc test, Pearson correlation coefficient, and hierarchical regression analysis using SPSS version 24. Results: The self regulation of preschool children (${\beta}=-.358$, p<.001) was the factor most closely associated with smartphone overdependency. The second most closely associated factor was children's use of a smartphone 0.5-1 hour daily (${\beta}=-.249$, p=.005). Additional associated factors were mothers' use of a smartphone for 3-4 hours daily (${\beta}=.217$, p=.002), children's use of a smartphone for less than 0.5 hour daily (${\beta}=-.212$, p=.006), and children's use of a smartphone for 1-2 days per week (${\beta}=-.205$, p=.026). Conclusion: Based on the results of this study, it is necessary to try to develop guidelines and programs to prevent smart phone overdependency in preschool children.

The Effect of Manual Physical Therapy on Neck Disability Index in Myofascial Pain Syndromes: A Systematic Review

  • Kim, Chan-Myeong
    • 대한물리의학회지
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    • 제15권4호
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    • pp.21-28
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    • 2020
  • PURPOSE: The main purpose of this meta-analysis study was to identify the degree-of-effect size and the variables for the effects of manual physical therapy on myofascial pain syndrome. METHODS: This study collected six studies published between 2015.01.01 and 2019.12.31. The analysis result verified nine effect size data. The random-effect model was chosen because of the heterogeneity of the data. RESULTS: First, the full case showed the largest mean effect size of 2.297 (p < .001). Second, the size of the effect based on the fascial distortion model (FDM) intervention showed an effect size of 4.654 (p < .001). Third, the number of participants showed a 15 or less effect size of 2.612 (p > .058). The number of treatments showed a 10 less effect size of 2.844 (p > .129). The publication type showed a thesis effect size of 3.095 (p < .002). CONCLUSION: Manual physical therapy has a great effect on myofascial pain syndrome in the neck and shoulders, and that the effects differ according to the methods of intervention.

지하수 중 자연방사성물질의 위해성 관리에 대한 고찰 (International Trends in Risk Management of Groundwater Radionuclides)

  • 신동천;김예신;문지영;박화성;김진용;박선구
    • Environmental Analysis Health and Toxicology
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    • 제17권4호
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    • pp.273-284
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    • 2002
  • At present, the health risks associated with the natural radionuclides of ground water have become a concern as potential social problems. However, there are no regulatory actions or control strategies for such risks. Therefore, we have investigated and discussed the risks and associated management strategies for radionuclides in other countries. US EPA has proposed MCL (300 pCi/L) and AMCL (4,000 pCi/L) for radon, and 30 ppb for uranium, 15 pCi/L for gross-alpha and 5 pCi/L for radium as final MCLs. Also, Canada, WHO and European countries have their inherent management levels. Finally, we suggested several criteria for setting guidelines in our countries including exposure related criteria such as geological distribution, occurrence, exposure probability distribution, exposure population and multimedia exposure assessment, acceptable risk, and cost -benefit analysis. The national-scale exposure and risk assessment, and economic analysis should be conducted for producing and aggregating the representative information on these criteria.