• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.223.2-223.2
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• 2003

A rapid, sensitive and selective liquid chromatography-tandem mass spectrometric (LC/MS/MS) method for the determination of eupatilin in human plasma was developed. Eupatilin and internal standard, (S)-[N-3-(4-(2-(1-methyl-5-tetrazolyl)-pyridine-5-y1)- 3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide (DA-7867) were extracted from human plasma by liquid-liquid extraction and analyzed on a phenyl-hexyl column with the mobile phase of acetonitrile-ammonium formate (10 mM, pH 3.0) (60:40, v/v). (omitted)

• 지질공학
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• 제19권2호
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• pp.153-163
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• 2009

본 연구에서는 제주도 현무암에 대한 삼축압축시험을 실시하고 암석의 Mohr-Coulomb파괴규준과 Hoek-Brown파괴규준을 적용하여 강도정수를 산정하였다. 그리고 각각의 파괴규준에 의해 산정된 강도정수를 비교검토하여 각각의 파괴규준에 대한 특성을 고찰하였다. 암석의 Mohr-Coulomb파괴규준을 적용한 결과 표선리 현무암의 경우 점착력은 5.35 MPa, 내부마찰각은 $50.25^{\circ}$이고, 조면암질 현무암의 경우 점착력은 16.99 MPa, 내부마찰각은 $60.66^{\circ}$이며, 스코리아의 경우 점착력은 2.33 MPa, 내부마찰각은 $37.05^{\circ}$이다. 암석의 Hoek-Brown의 파괴규준에 대한 회귀분석결과를 토대로 암석의 점착력과 내부마찰각을 선정할 수 있다. 표선리 현무암의 경우 점착력은 4.77 MPa, 내부마찰각은 $52.47^{\circ}$이고, 조면암질 현무암의 경우 점착력은 14.69 MPa, 내부마찰각은 $60.70^{\circ}$이며, 스코리아의 경우 점착력은 2.22 MPa, 내부마찰각은 $47.60^{\circ}$이다. 이상의 결과를 토대로 Mohr-Coulomb의 파괴포락선과 Hoek-Brown의 파괴규준으로부터 추정된 파괴포락선을 비교한 결과 Hoek-Brown의 파괴규준은 Mohr-Coulomb의 파괴규준보다 점착력은 대체로 낮게 평가되는 반면, 내부마찰각은 크게 평가되고 있다.

• 경영정보학연구
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• 제3권1호
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• pp.47-60
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• 2001

• Mass Spectrometry Letters
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• 제3권2호
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• pp.47-49
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• 2012

Myoglobin was hydrolyzed by microwave-assisted weak acid hydrolysis with 2% formic acid at $37^{\circ}C$, $50^{\circ}C$, and $100^{\circ}C$ for 1 h. The most effective hydrolysis was observed at $100^{\circ}C$. Hydrolysis products were investigated using matrixassisted laser desorption/ionization time-of-flight mass spectrometry. Most cleavages predominantly occurred at the C-termini of aspartyl residues. For comparison, weak acid hydrolysis was also performed in boiling water for 20, 40, 60, and 120 min. A 60- min weak acid hydrolysis in boiling water yielded similar results as a 60-min microwave-assisted weak acid hydrolysis at $100^{\circ}C$. These results strongly suggest that microwave irradiation has no notable enhancement effect on acid hydrolysis of proteins and that temperature is the major factor that determines the effectiveness of weak acid hydrolysis.

• 한국식품저장유통학회지
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• 제18권5호
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• pp.706-713
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• 2011

본 연구는 단감분말을 부재료로 이용하여 0%, 3%, 4%, 5% 별로 첨가량을 달리한 단감 고추장을 제조하여 $20^{\circ}C$에서 90일 동안 숙성 시키면서 화학적 특성을 조사하였다. 수분함량은 모든 처리구에서 숙성 기간 내내 증가하는 경향을 보였으며, 단감 분말 첨가 고추장과 대조구 사이에 유의적 차이는 없었다. pH는 숙성 기간 중 모든 시료에서 숙성기간이 증가함에 따라 서서히 감소하는 경향을 보였으며, 숙성 60일부터 4.64-4.67 수준을 유지하였다. 적정산도의 변화는 pH와 반대로 숙성기간 동안 증가하는 경향을 보여숙성 90일 째 단감 분말 첨가 고추장의 적정 산도는 0.147-0.156 mg%수준이었다. 당도는 숙성 초기 $33.67-39.67^{\circ}brix$로 나타났으며 단감 분말 첨가량이 증가할수록 당도는 높아지는 경향을 보였다. 아미노태 질소는 숙성 초기에는 241.27-245.47 mg%수준이었고, 숙성 60일 이후에는 단감 분말 3%, 4% 첨가구에서 아미노태 질소 함량이 유의적으로 높게 나타났다(p<0.05). 숙성 최종 단계인 90일차에 아미노태 질소 함량은 357.47-371.53 mg% 수준이었다.숙성 기간 내내 증가하는 경향을 보였다. 알코올 함량은 숙성기간이 증가함에 따라 점차 증가하는 경향을 보여 숙성 70일 째알코올 함량은 0.96-0.108%로 가장 높았고, 이후 모든 처리구에서 약간 감소하는 경향을 보였다.

• 한국응용과학기술학회지
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• 제16권3호
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• pp.223-230
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• 1999

This study was performed to determine optimum level of ethanol intake with weanling male rats. The weanling rats and the experimental diets were divided into 5 groups, control, A, B, C, D group in according to the levels of ethanol intake for 10 weeks. In the result of their serum analyses, we suggest that an adequate intake of ethanol is 1.47ml/kg/day. If body weight of any man is 60kg, he can drink about 90ml(1.47*60=88.2) ethanol/day. It corresponds to 360ml [90=360*(25/100)] of 25% SOJU.

• Nuclear Engineering and Technology
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• 제47권3호
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• pp.253-259
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• 2015

The fast neutron reactor BOR-60 is one of the key experimental facilities worldwide to perform large-scale tests of fuel, absorbing, and structural materials for advanced reactors. The BOR-60 reactor was put into operation in December 1969, and by the end of 2014 it had been operating on power for ~265,000 hours. BOR-60 still demonstrates potential capabilities to extend the lifetime of sodium-cooled fast reactors. The BOR-60 lifetime should have expired at the end of 2014. Over the past few years, a great scope of work has been performed to justify the possibility of extending its lifetime. The work included inspection of the equipment conditions, calculations and experimental research on operating parameters and the conditions of nonremovable components, investigation of the structural material samples after their long-term operation under irradiation, etc. Based on the results of the work performed, the residual lifetime was evaluated and the reactor operator made a decision to extend the lifetime period of the BOR-60 reactor. After considering both a set of documents about the reactor conditions and the positive decision of independent experts, the Regulatory Authority of the Russian Federation extended the BOR-60 operating license up to 2020.

• 미생물학회지
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• 제38권4호
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• pp.275-275
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• 2002

Pseudomonas sp. S-47 is capable of catabolizing 4-chlorobenzoate (4CBA) as carbon and energy sources under aerobic conditions via the mesa-cleavage pathway. 4CBA-dioxygenase and 4CBA-dihydrodiol dehydrogenase (4CBA-DD) catalyzed the degradation af 4CBA to produce 4-chlorocatechol in the pathway. In this study, the xylL gene encoding 4CBA-DD was cloned from the chromosomal DNA of Pseudomonas sp. S-47 and its nucleotide sequence was analyzed. The xylL gene was found to be composed of 777 nucleotide pairs and to encode a polypeptide of 28 kDa with 258 amino acid residues. The deduced amino acid sequence of the dehydrogenase (XylL) from strain S-47 exhibited 98% and 60% homologies with these of the corresponding enzymes, Pseudomonas putida mt-2 (XyIL) and Acinetobacter calcoaceticus (BenD), respectively. However, the amino arid sequences show 30% or less homology with those of Pseudomonas putida (BnzE), Pseudomonas putida Fl (TodD), Pseudomonas pseudoalcaligenes KF707 (BphB), and Pseudomonas sp. C18 (NahB). Therefore, the 4CBA-dihydrodiol dehdrogenase of strain S-47 belongs to the group I dehydrogenase involved in the degradation of mono-aryls with a carboxyl group.

• The Journal of Korean Physical Therapy
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• 제30권2호
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• pp.47-53
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• 2018

Purpose: To find the effect of visual feedback of head angle with using a mobile posture-aware system on craniocervical angle and neck and shoulder muscles fatigue for preventing or decreasing the forward head posture. Methods: Twenty-four healthy young adults in Chungbuk to participate in this study. The subjects started to watch a movie clip for 10 minutes with visual feedback in $0^{\circ}$, $30^{\circ}$, and $60^{\circ}$ of head angles. During the task, surface electromyography (EMG) was used to collect data from the upper trapezius (UT), sternocleidomasetoid muscle (SCM), cervical erecter spinae (CES) during watching the smartphone. Craniocervical angles were measured using a sagittal-view photograph of the subject in a sitting posture. A one-way repeated analysis of variance with a significant level of 0.05 used for statistical analysis. Results: Craniocervical angle with $0^{\circ}$ visual feedback was significantly greater than $30^{\circ}$ and $60^{\circ}$. Craniocervical angle with $30^{\circ}$ visual feedback was significantly greater than $60^{\circ}$. In addition, MDF of UT muscles in $0^{\circ}$ and $30^{\circ}$ of visual feedback was significantly greater than $60^{\circ}$. Conclusion: We concluded that $0^{\circ}$ visual feedback of head angle with using a mobile posture-aware system would be beneficial to prevent or decrease forward head posture during watching a smartphone. We also could recommend using of $30^{\circ}$ visual feedback in case of caring UT muscle fatigue primarily.

• 복식문화연구
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• 제11권1호
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• pp.66-74
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• 2003

This study is to improve the worst lightfastness of a natural dye. To modify the fiber surface, low temperature oxygen plasma was carried out on silk fabric. The result is followed below after the examination of surface shape, dyeability, color change, UV absorbent influence and lightfastness. 1. When electric discharge outputs are 60W, 80W and 100w, and processing times are 10minutes, 20minutes and 40minutes, the etching effect of surface increased as electric discharge outputs and processing times increased. 2. When examined UV absorbent for 5hours, 10hours, 20hours, 40hours and 80hours, the value changes of E are 1.47, 2.51, 2.91, 3.71, 4.51 and 5.31 in case of Al pre-mordanting/ prasma 80W, 20min./ UVabsorbent 5% (100:1), 2.31, 2.47, 3.84, 3.90, 3.61 and 4.42 in case of Al pre-mordanting/prasma 80W, 20min.1 UV absorbent 5% (o.w.f.). The lightfastness decreased when UV absorbent increased. 3. Dyeability of the samples pre-treated with five different methods was in the following order: plasma processing for 20minutes at 60W/Al pre-mordanting > Al pre-mordanting > plasma processing for 20minutes at 60W > Al after-mordanting. non mordanting Plasma treatment had superior effect on dyeability. 4. When UV absorbent was applied in fabric, the sample under higher electric discharge out puts showed more effective in improving lightfastness.