• The Transactions of the Korea Information Processing Society
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• v.2 no.4
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• pp.509-523
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• 1995

With the diversified and enlarged softwares, the issue of software maintenance became more complex and difficult consequently, the cost of software maintenance took up the highest portion in the software life cycle. At the same time, in order to develop or use software for general computers the development environment will be changed to incorporate user-friendly 4GL (Fourth generation Language). Therefore, it is required to take a closer look at the languages such as COBOL, C, FORTRAN, PASCAL which have source code comprised of 4GL and investigate the method of analysis and reuse for program understanding since a lot of research has been done with these languages in program maintenance. The purpose of this paper is to propose reverse engineering tool in 4GL and find an effective way of understanding and maintaining the program by transforming source code comprised of 4GL to meta language and designing and implementing Document Generator, Report Generator, Module Generator, Code Translator for program understanding.

• Journal of agricultural medicine and community health
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• v.4 no.1
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• pp.81-89
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• 1979

This study was undertaken to evaluate the present status of intestinal helminthic infection in rural areas of Korea from Dec. 1976 to Feb. 1979.The 4,311 stool specimens collected from 4 mountainous areas, 2 plain areas and 4 ri ver basins were examined. The methods employed were Kato's cellophane thick smear technique and brine fletation technique. The results are as follows. 1. The positive rate of intestinal helminch of any kind was 73.4%. It was 82.9% in river basins, 70. 2% in plain areas and 70. 4% in mountainous areas. 2. The positive rates of intestinal helmint.h were; Ascaris lumbricoides 42.5%, Trichocephalus trichiurus 51.4%, Hookworm 4.2%, Clonorchis sinensis 4.0%, Meta-gonimus yokogawai 5.7%, Hymenolepis nana 1.3%, Taenia species 1.0%, and Trichostrongyllus orientalis 1.2% respectively. 3. Sexual distribution of heiminthic infections showed higher rate in female than that of male except C. sinensis, H. nana, Taenia species, and. M. yokogawai. 4.Infection rates of T. trichiurus, Hook-worm and C. sinensis increased with age, but conversely H. nana were more prominent in younger age. 5. No geographical differen=e was noticed except that, M. yokogawai (20.9%), C sinensis (14.2%) in river basins ancl Taenia species (2.3%, by applying only stool examination) in mountainous areas were higher than the other 2 areas.

• YAKHAK HOEJI
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• v.42 no.2
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• pp.165-169
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• 1998

Inhibitory effects of 16 cinnamic acid analogs on formyl-Met-Leu-Phe(fMLP)-induced chemotaxis of rat polymorphonuclear leukocytes were determined by using a microchemotaxis appa ratus. 3,4-Dlhydrocinnamic acid called as caffeic acid exhibited the highest inhibitory effect on the chemotaxis among cinnamic acid analogs tested in this study. Hydroxycinnamic acids exhibited stronger inhibitory effects on the chemotaxis than cinnnamic acid. Hydroxycinnamic acids with one hydroxy group at ortho, meta or para position exhibited similar inhibitory effects on the chemotaxis with corresponding methoxy cinnamic acids, but 3,4-dihydroxycinnamic acid did stronger inhibitory effects than 3,4-dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exhibited weaker inhibitory effects on the chemotaxis than 1,2-dimethoxy-4-propenylbenzene and 3,4-dimethoxy cinnamonitrile with -CH=CHCN or -CH=$CHCH_3$, group instead of -CH=CHCOOH group. 4-Hydroxy cinnamic acid and 3,4-dihydroxycinnamic acid exhibited stronger exhibitory effects on the chemotaxis than 3-(4-hydroxyphenyl) propionic acid and 3,4-dihydroxyhydrocinnamic acid with -$CH_2CH_2$COOH group instead of -CH=CHCOOH group.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.4
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• pp.247-254
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• 2015

Ride comfort is one of the major factors in evaluating the performance of the vehicle. Tire is closely related to the ride comfort of the vehicle as the only parts in contact with the road surface directly. Vertical stiffness which is one of the parameters to evaluate the tire performance is great influence on the ride comfort. In general, the lower the vertical stiffness, the ride comfort is improved. Research for improving the ride comfort has been mainly carried out by optimizing the shape of the pneumatic tire. However, demand for safety of the vehicle has been increased recently such as a run-flat tire which is effective in safety improvement. But a run-flat tire have trouble in practical use because of poor ride comfort than general tire. Therefore, In this paper, the research was carried out for improving the ride comfort through the optimization of the SIR shape inside a run-flat tire. Meta-model was generated by using the design of experiment and it was able to reduce the time for the finite element analysis of optimization. In addition, Shape optimization for improving the ride comfort was performed by using the genetic algorithm which is one of the global optimization techniques.

• International journal of advanced smart convergence
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• v.4 no.1
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• pp.88-92
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• 2015

Today, the medical information system has evolved in the way of integrated healthcare IT information systems. Therefore, it is trying to build advanced U-Healthcare service. Though the U-Healthcare environments is exchanged the information between systems in many cases, however since the each system is different, the integration and exchange of data is difficult. To overcome this problem, in this paper it proposes that we suggests a possible DBaaS(DataBase as a Service) for the heterogeneous integration of medical information management and data exchange. First, the proposed system builds DBaaS cloud by integrating the meta-DB Schema level and DB Schema for each hospital. And, the mapping the schema data and the existing hospital information system is possible using the International Standard HL7. By applying the proposed method to the hospital system, it comes true the efficient exchange of information between the patients, doctors, staffs through the data mapping of the one to multi-system.

• Journal of Yeungnam Medical Science
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• v.37 no.4
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• pp.277-285
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• 2020

Tuberculosis (TB) is still a major health problem worldwide. Especially, multidrug-resistant TB (MDR-TB), which is defined as TB that shows resistance to both isoniazid and rifampicin, is a barrier in the treatment of TB. Globally, approximately 3.4% of new TB patients and 20% of the patients with a history of previous treatment for TB were diagnosed with MDR-TB. The treatment of MDR-TB requires medications for a long duration (up to 20-24 months) with less effective and toxic second-line drugs and has unfavorable outcomes. However, treatment outcomes are expected to improve due to the introduction of a new agent (bedaquiline), repurposed drugs (linezolid, clofazimine, and cycloserine), and technological advancement in rapid drug sensitivity testing. The World Health Organization (WHO) released a rapid communication in 2018, followed by consolidated guidelines for the treatment of MDR-TB in 2019 based on clinical trials and an individual patient data meta-analysis. In these guidelines, the WHO suggested reclassification of second-line anti-TB drugs and recommended oral treatment regimens that included the new and repurposed agents. The aims of this article are to review the treatment strategies of MDR-TB based on the 2019 WHO guidelines regarding the management of MDR-TB and the diagnostic techniques for detecting resistance, including phenotypic and molecular drug sensitivity tests.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.4 s.247
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• pp.465-472
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• 2006

Recently, the regulations of the government and the concerns of people have rise to the interest in noise pollution levels as compared to other vehicles. In this area, many researchers have studied to reduce this noise in the field of automotive engineering. This paper proposes an optimal design scheme to reduce the noise of the intake system by adapting Kriging with two meta-heuristic techniques. For this, as a measuring tool for the performance of the intake system, the performance prediction software, was used. Then, the length and radius of each component of the current intake system are selected as input variables and the orthogonal arrays is adapted as a space-filling design. With these simulated data, we can estimate a correlation parameter in Kriging by solving the nonlinear problem with a genetic algorithm and find an optimal level for the intake system by optimizing Kriging estimated with simulated annealing. We notice that this optimal design scheme gives noticeable results and is a preferable way to analyze the intake system. Therefore, an optimal design for the intake system is proposed by reducing the noise of its system.

• Tuberculosis and Respiratory Diseases
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• v.77 no.4
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• pp.161-166
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• 2014

Since tuberculosis (TB) remains a major global health concern and the incidence of multi-drug resistant (MDR)-TB is increasing globally, new modalities for the detection of TB and drug resistant TB are needed to improve TB control. The Xpert MTB/RIF test can be a valuable new tool for early detection of TB and rifampicin resistance, with a high sensitivity and specificity. Late-generation fluoroquinolones, levofloxacin, and moxifloxacin, which are the principal drugs for the treatment of MDR-TB, show equally high efficacy and safety. Systemic steroids may reduce the overall TB mortality attributable to all forms of TB across all organ systems, although inhaled corticosteroids can increase the risk of TB development. Although fixed dose combinations were expected to reduce the risk of drug resistance and increase drug compliance, a recent meta-analysis found that they might actually increase the risk of relapse and treatment failure. Regarding treatment duration, patients with cavitation and culture positivity at 2 months of TB treatment may require more than 6 months of standard treatment. New anti-TB drugs, such as linezolid, bedaquiline, and delamanid, could improve the outcomes in drug-resistant TB. Nontuberculous mycobacterial lung disease has typical clinical and immunological phenotypes. Mycobacterial genotyping may predict disease progression, and whole genome sequencing may reveal the transmission of Mycobacterium abscessus. In refractory Mycobacterium avium complex lung disease, a moxifloxacin-containing regimen was expected to improve the treatment outcome.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.10
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• pp.1095-1102
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• 2014

In this paper, We proposed the approach of GPU and motion vector to analysis the Human activity in real-time surveillance system. The most important part, that is detect blob(human) in the foreground. We use to detect Adaptive Gaussian Mixture, Weighted subtraction image for salient motion and motion vector. And then, We use motion vector for human activity analysis. In this paper, the activities of human recognize and classified such as meta-classes like this {Active, Inactive}, {Position Moving, Fixed Moving}, {Walking, Running}. We created approximately 300 conditions for the simulation. As a result, We showed a high success rate about 86~98%. The results also showed that the high resolution experiment by the proposed GPU-based method was over 10 times faster than the cpu-based method.

• Journal of Pharmaceutical Investigation
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• v.41 no.4
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• pp.233-238
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• 2011

DEET, N,N'-diethyl-m-toluamide, is the most commonly used mosquito repellent. However, it can easily permeate through skin leading to toxic effects. A recent study showed that the ortho analogue of DEET showed enhanced repellency with reduced permeation compared to the commercially used meta analogue. Thus, in order to understand the differences in properties and effectiveness among the m-, o- and p-analogues of DEET, an HPLC-UV method was developed for separately analyzing the three analogues. Moreover, stability profiles at temperatures ranging from $30^{\circ}C$ to $70^{\circ}C$ as well as pH ranging from pH 3 to pH 9 have been determined. All three analogues were stable with no degradation observed during the 5 day period. o-DEET therefore could be further developed into a safer and more effective mosquito repellent.