• Journal of KIISE:Software and Applications
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• v.29 no.11
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• pp.837-850
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• 2002

In this paper, we propose an EEG-based response time prediction method during a yes/no cognitive decision task. In the experimental task, a subject goes through responding of visual stimulus, understanding the given problem, controlling hand motions, and hitting a key. Considering the subject's varying brain activities, we model subjects' mental states with defining CT (cut time), ST (selection time), and RP (repeated period). Based on the assumption between ST and RT in the mental model, we predict subjects' response time by detection of selection time. To recognize the subjects' selection time ST, we extract 3 types of feature from the filtered brain waves at frequency bands of $\alpha$, $\beta$, ${\gamma}$ waves in 4 electrode pairs combined by spatial relationships. From the extracted features, we construct specific rules for each subject and meta rules including common factors in all subjects. Applying the ST detection rules to 8 subjects gives 83% success rates and also shows that the subjects will hit a key in 0.73 seconds after ST detected. To validate the detection rules and parameters, we test the rules for 2 subjects among 8 and discuss about the experimental results. We expect that the proposed detection method can be a basic technology for brain-computer-interface by combining with left/right hand movement or yes/no discrimination methods.

• The korean journal of orthodontics
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• v.40 no.1
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• pp.27-33
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• 2010

Objective: The need to bond orthodontic brackets onto various alloys has increased because of the increasing demand for adult orthodontic treatment. This study tried to evaluate the shear bond strength between gold alloy and metal bracket using light emitting diode (LED) light curing after metal primer and silicoating surface conditioning. Methods: Half of the type III gold alloy plates were treated with sandblasting with aluminum oxide and metal primer containing 4-META. the other half were treated with silica and silane. Metal brackets were bonded with Transbond XT light curing adhesive on these plates and shear bond strength were evaluated 1 hour, 6 hours, and 24 hours later. The differences of shear bond strength between groups were evaluated with two-way ANOVA. Results: The results showed higher bond strength in the silicoating group and a tendency of bond strength increase over time. Conclusions: When using LED curing lights for metal bracket bonding to alloy surfaces, long curing time and silicoating can produce a reliable bonding strength.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.293-298
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• 2018

The aim of this study was to survey the effects of planned exercise over the age of 65 in male and female with regard to their self-efficacy, depression, and life satisfaction, based on the literatures of 14 master and doctoral dissertations published between 2004 and 2014. The subjects with program exercise habit were chosen considering the generalization of the physical characteristics of elderly subjects. The exercise duration was 50 minutes for 3 times a week for 12 to 24 weeks. Exercise intensity was an optimal aerobic exercise plan that the subjects themselves could perform. The average effect size of self-efficacy was 0.793 (26.1% increased), depression was -0.91(31.9% decreased), and life satisfaction was 1.506 (43.4% increased). These indicate that post-exercise psychological variables had a positive effect on self-efficacy and life satisfaction by lowering depression after regular exercise. Therefore, it is necessary to increase regular exercise participation and to provide sustainable scientific information for the aged and healthy living of the elderly.

• Korean Journal of Environmental Agriculture
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• v.10 no.2
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• pp.167-177
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• 1991

O-ethyl S-methyl ethylphosphonothioate [$LD_{50}$ (rat, oral) 4.6mg/kg ; $K_i$(bovine erythrocyte acetylcholinesterase) 303 $M^{-1\;min-1}$] was selected as a model compound to study the mode of action of O, S-dialkyl alkylphosphonothioates which have been hypothesized to be toxic via a bioactivation process. Two chemical oxidants, meta-chloroperoxybenzoic acid and monoperoxyphthalic acid, and rat liver microsomal oxidases were used to mimic the action of mixed function oxidases on the model compound. The formation of S-oxide, a very unstable active intermediate, was proposed based on the identification of metabolic products.Furthermore, a trapping experiment with ethanol showed that the unstable intermediate S-oxide had the ability to phosphorylate acetylcholinesterase which is an important enzyme in nerve systems. The S-oxide intermediates are presumed to be responsible for the toxicity of O,S-dialkyl alkylphosphonothioates.

• Applied Biological Chemistry
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• v.43 no.2
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• pp.95-99
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• 2000

A series of hetero ring (X) substitued chalcone derivatives with farnesyl protein transferase (FPTase) inhibition activities $(pI_{50})$ values determined in vitro is analyzed by modified Free-Wilson (F-W) and Hansch method for quantitative structure activity relationship (QSARs). On the basis of F-W analysis on the FPTase inhibitory activity of a training set of the compounds, none of the (X)-substituents were not contribute the activity. But the net charge of ${\alpha}$ carbon atom is contribute the activity than that of ${\beta}$ carbon atom. And the relative orders of the (Y)-substituents on the activity are ortho>meta>para-substituents. According to Hansch approach, the activities would depend largely on the optimal, $(R_{opt.}=-0.35)$ resonance effect with ortho substituted $(I_o>0)$ electron donating group (R<0) and STERIMOL parameter, $B_1$ constant. The inhibition activity between hetro ring substituents have been a proportioned with each others and none substituent(H), 45 showed the highest FPTase inhibition $(pI_{50}=4.30)$ activity.

• Journal of Korea Water Resources Association
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• v.51 no.4
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• pp.281-291
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• 2018

Harmony search algorithm (HSA), developed by Hydrosystem lab. in Korea University in 2001, was a new meta-heuristic optimization algorithm inspired by the iterative improvision process of Jazz music players where the best harmony is eventually produced. HSA is now one of the most well-known meta-heuristic algorithms (as proven by its cited number of the first published paper more than 3,600 times as of January 11th 2018 based on Google Scholar citation) and has been applied to diverse research domains such as not only water resources and civil engineering but also in medical science, business, and humanities. This paper is a review article written with the wish for wider application of HSA and other optimization algorithms, especially in the domain of water resources engineering. Therefore, this paper first briefly introduces the mechanism and operators of HSA and then reviews its application area and citation frequency per research domain. In addition, recent globalization of HSA will be investigated and summarized by checking the current status of related international conferences and on-going research projects. After reviewing previous domestic papers with optimization algorithms specifically published in the water resources domain, this paper is finalized by delivering some suggestions to encourage the application of optimization algorithms including HSA.

• Journal of Animal Science and Technology
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• v.62 no.1
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• pp.31-42
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• 2020

The aim of this study was to investigate the effects of 3-nitrooxypropanol (NOP) on gas production, rumen fermentation, and animal performances depending on animal type using a meta-analysis approach. A database consisted of data from 14 studies, 18 experiments and 55 treatments. The supplementation of NOP linearly decreased methane (CH₄) emissions [g/kg dry matter intake (DMI)] regardless of animal type and length of experimental period (beef, p < 0.0001, R² = 0.797; dairy, p = 0.0003, R² = 0.916; and long term, p < 0.0001, R² = 0.910). The total volatile fatty acids (VFA) concentration and the proportion of acetate, based on beef cattle database, were significantly decreased with increasing NOP supplementation (p = 0.0015, R² = 0.804 and p = 0.0003, R² = 0.918), whereas other individual VFAs was increased. Based on the dairy database, increasing levels of NOP supplementation linearly decreased proportion of acetate (p = 0.0284, R² = 0.769) and increased that of valerate (p = 0.0340, R² = 0.522), regardless of significant change on other individual VFAs. In animal performances, the DMI, from beef cattle database, tended to decrease when the levels of NOP supplementation increased (p = 0.0574, R² = 0.170), whereas there was no significant change on DMI from dairy cattle database. The NOP supplementation tended to decrease milk yield (p = 0.0606, R² = 0.381) and increase milk fat and milk protein (p = 0.0861, R² = 0.321, p = 0.0838, R² = 0.322). NOP is a viable candidate as a feed additive because of its CH₄ mitigation effects, regardless of animal type and experiment period, without adverse effects on animal performances.

• Journal of dental hygiene science
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• v.17 no.2
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• pp.160-167
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• 2017

The purpose of this systematic review was to investigate the association between periodontal disease and chronic kidney disease. A search of Embase, PubMed and The Cochrane Library databases was performed up to April 17, 2016. Article selection was based on cohort study design and the study subjects were patients with periodontal disease or severe periodontal disease. The final result was development of chronic kidney disease and kidney function decrease based on the estimated glomerular filtration rate values. The quantitative synthesis of the final selected articles was assessed using Review Manager statistical analysis software. A fixed-effects model meta-analysis was performed to estimate the degree of association between periodontal disease and chronic kidney disease. The search strategy identified 3,018 potentially eligible articles, of these, four studies were finally selected for meta-analysis, revealing that periodontal disease was significantly associated with the risk of developing chronic kidney disease (odds ratio, 1.65; 95% confidence interval, 1.44~1.90; p<0.001). In order to prevent the development of chronic kidney disease and kidney function decrease it is important to prevent periodontal disease, as well as minimizing the traditional risk factors known to reduce the quality of life of patients and increase disease burden.

• Journal of Ginseng Research
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• v.30 no.4
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• pp.212-219
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• 2006

Research literatures (e.g. research report, scientific paper and thesis, published between 2001 and 2005) of 332 collected from KISTI, KISS, ARPC databases were investigated and analyzed to give an overview of domestic ginseng researches. Most of recent ginseng researches have been performed by private nonprofit institutions and individuals, which suggests that a role of public institution fur ginseng researches needed to be enlarged. In terms of research fields, cultivation and agricultural researches have been mainly accomplished in ginseng research. Cell physiology and reproductive function researches occupied large part of pharmacological studies, but clinical studies were relatively limited. Studies on general food products development have taken the main part in fields of food products including functional foods. As the result of analysis of 312 domestic ginseng patents by classifications of world international property organization (WIPO), it was categorized into food technology, medicinal fermentation development technology, fermentation technology, and agriculture-fisheries technology. This integrated overview of the widely scattered ginseng literatures shows current general research trends in Korea and will be able to suggest further needs on cultivation, studies and industralization of ginseng.

• The KIPS Transactions:PartD
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• v.18D no.4
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• pp.261-274
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• 2011

In recent competitive business environment each enterprise has to be agile and flexible. For these purposes run-time monitoring ofservices provided by an enterprise and early decision making through this becomes core competition of the enterprise. In addition, in order to process various innumerable events which are generated on enterprise systems techniques which make filtering of meaningful data are needed. However, the existing study related with this is nothing but discovering of service faults by monitoring depending upon API of BPEL engine or middleware, or is nothing but processing of simple events based on low-level events. Accordingly, there would be limitations to provide useful business information. In this paper, through situation detection an extended complex event model is presented, which is possible to provide more valuable and useful business information. Concretely, first of all an event processing architecture in an enterprise system is proposed, and event meta-model which is suitable to the proposed architecture is going to be defined. Based on the defined meta-model, It is presented that syntax and semantics of constructs in our event processing language including various and progressive event operators, complex event pattern, key, etc. In addition, an event context mechanism is proposed to analyze more delicate events. Finally, through application studies application possibility of this study would be shown and merits of this event model would be present through comparison with other event model.