• Korean Journal of Health Education and Promotion
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• v.21 no.4
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• pp.15-33
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• 2004

With growing significance of psychological well-being in the worksite, the purpose of this analysis was to overview the empirical studies on worksite stress management and to identity the overall effect of worksite health promotion programs on stress management through meta-analysis. Literature retrieval was conducted on-line first in MEDLINE, EBSCOhost Academic Search Premier, and PSYCHINFO databases in public health, psychology, sociology, and human resource management areas. All studies written in English and published in the peer-reviewed journals during 1990 and 2002 were recruited. Key words used in literature retrieval were 'worksite,' 'intervention,' 'program,' 'work stress,' 'strain,' 'burnout,' 'management,' 'prevention,' 'education,' and 'health promotion.' A total of 18 worksite intervention studies with 48 effect sizes were analyzed and the results were as follows. Approximately 60％ of the studies had quasi-experimental design and were conducted in manufacturing company and public sector. General psychological strains and burnout were frequently used measures of psychological stress. The lecturing and discussion typed intervention and the participatory problem-solving typed intervention were employed more than others in the studies. The average effect (r: pearson's simple correlation coefficient) weighted by sampling error was -0.14 (-0.32 to 0.05). In the conventional category of effects this is a small effect ranging from -0.59 to 0.05. Binomial effect size showed that success rates increased from 43％ without intervention to 57％ after an intervention. Sampling error explained 47.14％ of the observed variance and its effectiveness on stress management were heterogeneous. In regression analysis with suspected moderating factors affecting the worksite interventions, research design was the only significant moderating factor. The studies with quasi-experimental design had greater effects than the studies with experimental design.

• Journal of the Korea Society for Simulation
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• v.17 no.4
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• pp.209-218
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• 2008

The Unified Modeling Language becomes popular to specify, visualize, construct, and document software-intensive systems, especially in supporting the design phase of software engineering. Most of designs in UML have focused on firm designing of software system structure. Recently, some researches have raised additional demands in many emerging complex software systems, such as aspect-oriented design. In this paper, we work on the dynamic aspect of policy-driven architecture. We present a UML-based high-level modeling of policy-driven management which is applicable in various application domains. In order to manage a number of activities of applications, dynamics and flexibility should be supported with policies consistently on different resources in the same context. Thus, a methodology of meta-modeling to represent dynamic aspects of policy-driven architecture is studied. Based on our methodology, we could achieve meta-modeling to develop a number of policy-driven management applications.

• Journal of KIISE:Databases
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• v.33 no.4
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• pp.363-371
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• 2006

In spite of computer's development, the present state of a lot of electronic documents overflowed it's going to be more difficult to get appropriate information. Therefore it's more important to get meaningful information than to focus on the speed of processing. Semantic web enables and intelligent processing by adding semantic meta data on your web documents. Also as the semantic web grows, the knowledge resource is more important. In this paper, we propose a RDF storage system using relational database model aimed at intelligent processing by adding semantic meta data on your web documents, also a query processor aimed at query processing through the storage system. By using relational model, we could overcome a weakness of object or memory model.

• Journal of Korean Medicine Rehabilitation
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• v.27 no.2
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• pp.39-54
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• 2017

Objectives This study aimed to search the Chinese literature on acupotomy for lumbar disc herniation and to analyze their methodologies. Methods Using 4 Chinese databases (CBM [www.sinomed.ac.cn], CNKI [www.cnki.net], WANFANG [www.wanfangdata.com], and WEIPU [www.cqvip.com]), we searched for clinical trials conducted in China over the past 10 years on acupotomy for lumbar disc herniation. The search terms used were "(腰椎椎間板脫出症 or 椎間板脫出症 or 椎間板脫出) and (针刀or 针刀松解术)" and we selected only meta-analyses that were published before December 2016. From among these meta-analyses, we excluded duplicates and selected the remaining 36 randomized controlled trials (RCTs) for our final analysis. Results The largest numbers of acupotomy papers were published in 2008 and 2013 (8 papers each). The average number of subjects was 120; the most common treatment method used for the control group was standard acupuncture (in 11 papers), and the most common concurrent treatment in the treatment group was massage (in 10 papers). The most common site of needle insertion was between the spinous processes, or at less than 0.5 cm on either side of the spinous processes (in 24 papers). The most common site of adhesion lysis was at the transverse process (in 24 papers). Two studies were blinded, and the mean Jadad score was 1.17. Conclusions A large number of RCTs on the use of acupotomy for lumbar disc herniation are conducted every year in China, and the procedure has been shown to be very effective, with few adverse effects. However, the average quality of the studies was not very high. Based on our study, we expect several high-quality clinical trials on acupotomy to be conducted in Korea in the future.

• Journal of Korean Clinical Nursing Research
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• v.23 no.2
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• pp.151-160
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• 2017

Purpose: The purpose of this study was to evaluate the effects of oral stimulation interventions on the transition from tube to oral feeding in preterm infants through systematic review. Methods: The randomized clinical trials published between 1980 and 2015 were searched using domestic and international databases, and five randomized studies were selected for this study. The quality of study was assessed by assessment tool from the SIGN and meta-analysis was performed using the Cochrane Review Manager software Version 5.3 (RevMan). Results: Oral stimulation intervention in preterm infants decreased the transition time from tube to oral feeding (Post Menstrual Age, Day of life). Especially, a significant medium effect size was found in the number of days needed on the transition (ES=-4.95, p=.02). The oral stimulation intervention also had a significant large effect on the length of stay at hospital (ES=-8.33, p<.001). Conclusion: Based on the findings, oral stimulation interventions could be useful to facilitate the transition from tube to oral feeding in preterm infants in terms of reducing the length of stay at hospital and the number of days needed on transition.

• Journal of Information Technology and Architecture
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• v.9 no.4
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• pp.443-453
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• 2012

In order to minimize the damage from system failures, systems over various fields are requested to contain the safety-critical features. In this paper, we deliver the considerable issues, especially, in the cyber physical systems that is recently used as a safety-critical system, as well as we propose the model driven architecture based on time as its the important factor. Based on meta-modeling approach, we introduce the time-based architecture which is associated with deadline, transition state, and threshold, and also we work out a design for this by using model driven architecture. We propose a realizable safety-critical architecture by means of showing failure handling components with safety transaction model from the meta-model. In the detailed models and the example, we design a basic safety processing state, a multiple safety processing state, and a compound safety processing state for completing the safety-critical system architecture.

• Journal of Korea Technology Innovation Society
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• v.20 no.4
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• pp.888-914
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• 2017

The main aim of this study is a meta-theoretical investigation to explain the current theoretical landscape of social innovation theories and researches. First of all, this paper makes a typology of social innovation based on concepts and sectors of social innovation. Second, in terms of societal innovation, which it is a kind of social innovation systematic approach, this paper draws some implications for social innovation policy. My key argument is that social innovation could be specified in three different sectors, public innovation, market innovation, and social economy innovation. However, all of them have attention to such as improving a quality of life and making society more sustainable, so it can be argued that those different sectors are structured on social innovation altogether with common goals. Finally, in order to activate the social innovation ecosystem, the government has to play a key role as a facilitator to make sustainable networks and a governance of social innovation that is needed to coordinate between different features and roles of social innovation sectors.

• Journal of Microbiology
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• v.43 no.4
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• pp.325-330
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• 2005

Rhodococcus sp. strain YU6 was isolated from soil for the ability to grow on o-xylene as the sole carbon and energy source. Unlike most other o-xylene-degrading bacteria, YU6 is able to grow on p-xylene. Numerous growth substrate range experiments, in addition to the ring-cleavage enzyme assay data, suggest that YU6 initially metabolizes 0- and p-xylene by direct aromatic ring oxidation. This leads to the formation of dimethylcatechols, which was further degraded largely through meta-cleavage path-way. The gene encoding meta-cleavage dioxygenase enzyme was PCR cloned from genomic YU6 DNA using previously known gene sequence data from the o-xylene-degrading Rhodococcus sp. strain DK17. Subsequent sequencing of the 918-bp PCR product revealed a $98\%$ identity to the gene, encoding meth-ylcatechol 2,3-dioxygenase from DK17. PFGE analysis followed by Southern hybridization with the catechol 2,3-dioxygenase gene demonstrated that the gene is located on an approximately 560-kb megaplasmid, designated pJY J1

• The Journal of Korean Society for School & Community Health Education
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• v.18 no.2
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• pp.27-42
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• 2017

Objectives: The purpose of this study was to investigate the characteristics of smoking prevention programs and their effectiveness for Korean school-aged children and adolescents by using systematic review and meta-analysis. Methods: Electronic searches were performed in RISS, NAL, DBPia, KISS using keywords according to inclusion criteria. 21 studies published from 2003 to the first half of 2017 that dealt with effects of smoking prevention programs for school-aged children and adolescents were selected for systematic review. Results: All 21 studies were quasi-experimental research designs. More than half of the programs(66.7%) were conducted for male and female. Most of the programs were conducted more than once a week(71.4%). 14 studies(66.7%) did not report using a theoretical model. Five dependent variables(knowledge of smoking, attitude toward smoking, non-smoking intention, self-assertiveness, and self-efficacy) were selected to measure the effectiveness of the smoking prevention programs. Knowledge of smoking was the most effective at hedge's g=0.673. Self-efficacy and self-assertiveness variables were statistically significant at hedge's g=0.461 and hedge's g=0.279, respectively. Effect sizes of attitude toward smoking and non-smoking intention were not statistically significant compared to the control group. As a result of the moderator effect analysis on the knowledge of smoking variable, the statistically significant variables were 'gender of participants'(p<0.01) and 'duration of the program'(p<0.001). Conclusions: The results of this study using systematic review and meta-analysis will be evidence-based data for researchers conducting smoking prevention programs in school-aged children and adolescents.

• Tuberculosis and Respiratory Diseases
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• v.84 no.4
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• pp.299-316
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• 2021

Background: The lack of effective medications for coronavirus disease 2019 (COVID-19) has led to a trend of drug repurposing such as the case of azithromycin which shows immunomodulatory and anti-viral effect. Several clinical trials have shown conflicting results. It is currently unclear whether the available evidence is in favor or against the use of azithromycin in COVID-19 patients. Thus, the aim of this study was to investigate the efficacy and safety of azithromycin in COVID-19 patients. Methods: Four independent reviewers selected relevant studies from PubMed, ScienceDirect, EBSCO, and ProQuest published prior to March 2021. The protocol used in this study has been registered in PROSPERO (CRD42020224967). Results: We included 17 studies and found that the mortality rate (odds ratio [OR], 0.95; 95% confidence interval [CI], 0.76-1.19), need of respiratory support (OR, 1.30; 95% CI, 0.98-1.73), hospitalization rate (standardized mean difference, 0.12; 95% CI, -0.02 to 0.27), and intensive care unit transfer (OR, 1.21; 95% CI, 0.79-1.86) of azithromycin-treated group did not differ significantly (p>0.05) from those of the control group. Azithromycin treatment did not significantly increase the risk of getting secondary infection (OR, 1.23; 95% CI, 0.83-1.82), hypoglycemia (OR, 0.73; 95% CI, 0.38-1.40), gastrointestinal problems (OR, 1.03; 95% CI, 0.73-1.45) or electrocardiogram abnormalities (OR, 1.16; 95% CI, 0.94-1.42). The overall quality of evidence ranged from low to very low. Conclusion: Azithromycin did not result in a superior clinical improvement in COVID-19 patients, although it was well-tolerated and safe to use.