• Journal of Korean Society for Quality Management
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• v.49 no.4
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• pp.447-466
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• 2021

Purpose: This article aims 1) to propose Quality 4.0 concept through surveying related literature, 2) to suggest key elements of Quality 4.0 by arranging the elements of Quality 4.0 that appeared in the literature, 3) to determine the levels of Quality 4.0, and 4) to suggest ideas for effective deployment of Quality 4.0. Methods: Eleven papers or documents are reviewed for Quality 4.0 concept; two papers and one document are investigated for key element extraction of Quality 4.0; and smart factory roadmap and industry 4.0 maturity model are studied to determine the levels of Quality 4.0. Results: 1) Quality 4.0 definition is proposed. 2) Three key elements are determined: data acquisition and analytics, connection and integration, and leadership and culture. 3) Six Quality 4.0 levels are determined. 4) Some suggestions are addressed for effective deployment of Quality 4.0. Conclusion: 1) Definition, key elements, levels, and some suggestions on effective deployment of Quality 4.0 are addressed. 2) Specific contents of Quality 4.0 education and training courses should be provided in the future. 3) Two future research directions are proposed.

• Archives of Pharmacal Research
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• v.18 no.4
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• pp.277-281
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• 1995

An anticoagulant, 4-hydroxy-3-[1, 2, 3, 4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyll-1 -naphthyl]coumarin (Flocoumafen) was synthesized in 8 steps starting from phenylacetyl shloride and anisole. The key step in the synthesis involves the reaction of 3-(4-methoxyphenyl)-1-teralol with 4-hydroxycoumarin to give 4-hydroxy-3 [1, 2, 3, 4-tetrahydro-3-[4-emthoxyphenyl]-1-naphthyl]coumarin.

• Bulletin of the Korean Chemical Society
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• v.16 no.4
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• pp.336-340
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• 1995

3',5'-Dimethoxy-4'-(2-vinyloxyethoxy)-4-nitrostilbene 2 and 3',5'-dimethoxy-4'-(2-vinyloxyethoxy)-2,4-dinitrostilbene 5 were prepared by the reactions of 2-iodoethyl vinyl ether with 3',5'-dimethoxy-4'-hydroxy-4-dinitrostilbene 1 and 3',5'-dimethoxy-4'-hydroxy-2,4-dinitrostilbene 4, respectively. Monomers 2 and 5 were polymerized with cationic initiators to obtain polymers with 3',5'-dimethoxy-4'-oxy-4-nitrostilbene and 3',5'-dimethoxy-4'-oxy-2,4-nitrostilbene, which are presumably effective chromophores for second-order nonlinear optical application in the side chain. The resulting polymers 3 and 6 were soluble in DMSO and DMF. The inherent viscosities of the polymers were in the range of 0.28-0.33 dL/g in DMSO. Polymers 3 and 6 showed a thermal stability up to 250 ℃ in TGA thermogram, and the Tg values obtained from DSC thermograms were in the range of 81-87°.

• Journal of Bio-Environment Control
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• v.4 no.2
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• pp.188-194
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• 1995

This study was carried out to investigate the effect of NH$_4$H$_2$PO$_4$ on pH stabilization in deep flow culture system using tap water, and to determine the optimum range of NH$_4$H$_2$PO$_4$ in culture solution. The pH of tap water is 7.5. The higher the concentration of NH$_4$H$_2$PO$_4$ was, the more the pH of nutrient solution was decreased. In NH$_4$H$_2$PO$_4$ 4/3-5/3 me/$\ell$, the pH of nutrient solution was 6-7.5 during the experiment. The highest brix(%) was obtained in NH$_4$H$_2$PO$_4$ 5/3-6/3 me/$\ell$. Leaf length, leaf width and stem-base diameter were highest in NH$_4$H$_2$PO$_4$ 2/3 me/$\ell$. The L and b＊ values were highest and the a＊ value was lowest in NH$_4$H$_2$PO$_4$ 8/3 me/$\ell$. Toxicity symptom of ammonium appeared in NH$_4$H$_2$PO$_4$ 8/3 me/$\ell$. It suggests that there was the relationship between leaf color and growth condition. It was concluded that NH$_4$H$_2$PO$_4$ 2/3 me/$\ell$ was good before harvest stage and NH$_4$H$_2$PO$_4$ 5/3-6/3 me/$\ell$ at harvest stage.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2010.04a
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• pp.403-407
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• 2010

건축 구조재료로 사용되는 소나무의 화재조건을 알아보기 위하여 콘칼로리미터(ISO 5660-1)를 이용하여 연소성질을 분석하였다. 자연 건조된 소나무에 $(NH_4)_2SO_4$, $NH_4H_2PO_4$, $(NH_4)_2HPO_4$ 등의 암모늄염을 이용하여 난연성을 부가하였다. 소나무의 함수율은 10.2%였으며 초기 열방출 곡선은 $(NH_4)_2HPO_4$인 경우 완만하게 증가하였으며 가장 좋은 난연성을 보였다. $HRR_{peak}$ 값은 무처리된 경우 $217\;kW/m^2$, $(NH_4)_2SO_4$, $NH_4H_2PO_4$, $(NH_4)_2HPO_4$인 경우에는 각각 $190\;kW/m^2$, $188\;kW/m^2$, $166\;kW/m^2$로 나타났다. 즉 $(NH_4)_2HPO_4$로 처리된 경우 23.5%의 감소현상이 관찰되었다. $HRR_{peak}$ 도달 시간은 무처리된 시험편(290s) 및 $(NH_4)_2SO_4$, $NH_4H_2PO_4$, $(NH_4)_2HPO_4$으로 처리된 시험편은 각각 298s, 263s, 313s로 나타났다. 연기 발생속도는 사용한 암모늄염 중 $(NH_4)_2SO_4$로 처리된 시험편이 가장 작게 관찰되어 저발연성 감연제 역할을 하는 것으로 판단된다.

• Journal of the Korean Chemical Society
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• v.52 no.1
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• pp.47-51
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• 2008

A simple synthetic strategy is described for one-pot synthesis of 5,7-diaryl-4,4-dimethyl-4,5,6,7-tetrahydropyridino[3,4-d]-1,2,3-selenadiazoles (11-15) in the presence of NaHSO4.SiO2 as a heterogeneous catalyst in dry media under microwave irradiation.Key words: One-pot synthesis, 3,3-Dimethyl-2,6-diarylpiperidin-4-one; 1,2,3-Selenadiazoles; Selenium dioxide; NaHSO4.SiO2 Heterogeneous catalyst.

• YAKHAK HOEJI
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• v.33 no.2
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• pp.80-86
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• 1989

2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-(2'-phenylsulfinyl) ethyl ester (10) or 2,6-Dimethyl-4-(2' or 3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-alkyl 5-(2-methylsulfonyl) ethyl ester (14a, b, c) were hydrolyzed by treatment with NaOH in aqueous EtOH solution to give 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester (4b), 2,6-Dimethyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester (4c) and 2,6-Dimethyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monoisopropyl ester (4d) in 80 -90% yield. By the same procedure, 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis (2'-methylsulfonyl) ethyl ester (15) gave 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid (4e) in 96% yield.

• KSBB Journal
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• v.14 no.4
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• pp.422-428
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• 1999

A transformat Alcaligence eutrophus GA5 harboring phbC gene from A. latus was cultivated for production of Poly(3-hydroxybutyrate-4-hydroxybutyrate)[P(3HB-4HB)] containing high molar fraction of 4-hydroxybutyrate(4HB)] containing high molar fraction of 4-hydroxybutyrate(4HB). Transformation did not influenced significantly on total cell growth, on total cell growth, concentration, and content of P(3HB-4HB), however, significantly influenced on 4HB molar fraction in P(3HB-4HB) increasing from 12.3 to 23.5 mol% after 48 h cultivation in two-stage using 1.0%(W/V) of ${\gamma}$-butyrolactone as a precursor compare to parent strain. Above increment may be due to the accelerated polymerization between 3HB and 4HB converted from precusor compound by amplified phbC gene. Citrate increased remarkbly total cell mass and P(3HB-4HB) concentration, but did not influenced on the molar fraction of 4HB, meanwhile, magnesium ion influenced on P(3HB-4HB) concentration and 4HB molar fraction significantly. The two-stage cultivation method was modified, in such a way minimizing P(3HB) accumulated inside of cell grown at first-stage, consquently, 26.3% of P(3HB-4HB) containing 61.0 mol% of 4HB fraction was obtained after 72hr. Furthermore, semi-homopolymeric P(4HB) containing 92.0 mol% of 4Hb was obtained, and its structure was confirmed by $^1$H-NMR.

• Archives of Pharmacal Research
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• v.26 no.2
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• pp.107-113
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• 2003

Several fused triazolo and ditriazoloquinoxaline derivatives such as 1-aryl-4-chloro-[1,2,4]triazolo[4,3-a]quinoxalines (3a-d), 4-alkoxy[1,2,4]triazolo[4,3-a]quinoxalines (4a,b), 4-substituted-amino-[1,2,4] triazolo[4,3-a]quinoxalines (5a-h), 1-(aryl)-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-thione (6), 4-(arylidenehydrazino )-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalines (10a-e) and [1,2,4]ditriazolo[4,3-a:3',4'-c]quinoxaline derivatives (11-13) have been synthesized and some of these derivatives were evaluated for antimicrobial and antifungal activity in vitro. It was found that compounds 3a and 9b possess potent antibacterial activity compared to the standard tetracycline.

• Journal of the Korean Chemical Society
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• v.52 no.4
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• pp.439-444
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• 2008