• 대한정형도수물리치료학회지
• /
• 제21권2호
• /
• pp.15-24
• /
• 2015

Background: Many people are suffering from neck and shoulder pain due to muscle weakness, muscle fatigue, lack of exercise and accidents during exercise. In this study we compared the effects of McKenzie method and Mulligan technique method. Method: we randomly selected men(10) and women(10) and they are the 20s students of Busan material K college. We divided for McKenzie exercise group and Mulligan exercise group. McKenzie exercise and mulligan exercise applied cervical area three times a week for three weeks. We compared with pre-experiment and after 1~3 week through measuring the electromyography (EMG) change and neck range of motion (ROM). Results: The changes in the EMG at each exercise group, there was a statistically significant difference in each week. Although there was a significant difference after 1 week between the exercise group, the changes in the neck ROM at each exercise group there was no statistically significant difference. Conclusion: After experiment, EMG and neck ROM were increased in McKenzie exercise group and Mulligan exercise group. But Mulligan exercise group showed the change better than McKenzie exercise group in early stage. We suggest the Mulligan exercise method for recovering in early stage of neck ROM.

• Food Science and Biotechnology
• /
• 제17권5호
• /
• pp.947-952
• /
• 2008

The unripe fruit of Momordica charantia (MC) has been shown to possess antidiabetic activity. However, the mechanism of its antidiabetic action has not been fully understood. In this study, the effects of the aqueous ethanolic extract of MC (AEE-MC) were evaluated on the apoptosis in pancreatic $\beta$-cells treated with a combination of the cytokines, interleukin (IL)-$1{\beta}$, tumor necrosis factor (TNF)-$\alpha$, and interferon (IFN)-$\gamma$. In MIN6N8 cells, the inhibitory effect of AEE-MC was significantly observed at 2 to 50 ${\mu}g/mL$: a 26.2 to 55.6% decrease of cytoplasmic DNA fragments quantified by an immunoassay. The molecular mechanisms, by which AEE-MC inhibited $\beta$-cell apoptosis, appeared to involve the inhibition on the expression of p21, Bax, and Bad, the up-regulation of Bcl-2 and Bcl-$X_L$, and the inhibition on the cleavage of caspase-9, -7, and -3 and poly (ADP-ribose) polymerase. This study suggests that MC may inhibit cytokine-induced apoptosis in $\beta$-cells and, thus, may contribute via this action to the antidiabetic influence in diabetes.

• Toxicological Research
• /
• 제22권3호
• /
• pp.301-306
• /
• 2006

Microcystin-LR(MC-LR), a cyanobacterial toxin produced by Microcystis aeruginosa, causes severe hepatotoxicity. Here we investigated the morphologic changes of rat hepatocyte spheroid induced by exposure of MC-LR($10^{-6}M$) in vitro. In addition, to determine the effects of such toxin in the process of hepatocyte spheroid formation, primarily isolated hepatocytes were incubated with MC-LR and the process of spheroid formation was observed. In both hepatocyte spheroid and suspension culture systems, the morphologic changes caused by MC-LR were noticible at 5 min post exposure and were characterized by the loss of microvilli, cytoplasmic vacuolation, the accumulation of lipid droplets, and blob formation. Especially, the size and numbers of blob on the cell surface were increased as the incubation time prolonged and the appearance of electron dense bodies were observed in the cytoplasm of hepatocyte at 20 min post exposure. Furthermore, bile canaliculi-like structures in the hepatocyte spheroids were slightly widened and the process of spheroids formation was inhibited in the isolated hepatocytes incubated with MC-LR. These results indicate that morphologic changes in. the hepatocyte membrane and organelles seem to be typical events in showing the MC-LR induced hepatotoxic effects and the spheroid culture method might be a useful experimental tool to evaluate hepatoxicity since it reflects the in vivo status of hepatocytes.

• 대한수의학회지
• /
• 제45권3호
• /
• pp.351-357
• /
• 2005

Here I describe a multiplex allele specific PCR-based approach for the rapid detection between Hanwoo and Holstein meat associated with Melanocortin 1 receptor (MC1R) gene. Specific and universal oligonucleotide primers were used in combination to detect the presence of a single nucleotide polymorphism within the bovine MC1R DNA sequence. The presence of the bovine MC1R gene is indicated by the production of a single control PCR product, whilst positive samples generate an alternative smaller specific product over the same region. The mutations in MC1R104 codon revealed depending on the presence or absence of an indicative fragment amplified from the wild-type allele of this codon. As little as 0.39 ng and 1.56 ng of genomic DNA of Hanwoo and Holstein could be detected by MAS-PCR assay, respectively. This technique, which is widely used in human genetic screening, provides a reliable and sensitive result that has not been documented for the identification of bovine coat color. The MAS-PCR assay approach was proven to be useful in complementing routine beef DNA analysis for differentiation of these MC1R variants and it would facilitate the screening of deceiving sales of Holstein meat in the butcher shop.

• Restorative Dentistry and Endodontics
• /
• 제10권1호
• /
• pp.127-134
• /
• 1984

This study was conducted to evaluate the sealing ability of McSpadden technique compared with lateral condensation and Engine reamer technique, and according to the degree of canal enlargement and the use and nonuse of sealer. Seventy single-rooted teeth were divided into 14 groups and each tooth was enlarged and obturated according to the purpose of this study. Obturated teeth were infiltrated by Indian ink and decalcified and cleared. The apical sealing ability was evaluated by measuring the degree of ink penetration into the canal. The results were as follows: 1. All the teeth filled by lateral condensation using gutta-percha cone and sealer proved better in canal sealing ability than McSpadden technique and Engine reamer technique, showing less ink penetration. 2. In the McSpadden technique, there was less ink penetration detected in using the sealer than not. 3. In all of the experimental methods, the difference of the degree of ink penetration according the degree of canal enlargement could not be accepted. 4. There was no significant difference in ink penetration degree between Engine reamer technique using sealer and McSpadden technique without sealer.

• 한국CDE학회논문집
• /
• 제14권3호
• /
• pp.186-196
• /
• 2009

Mass customization (MC) is a business practice that aims to provide customers with customized products and services at near mass production efficiency. To achieve the aim, a number of methods to implementing MC are proposed. However, most of them require changes in entire process of the company, which make companies hesitate to implement MC even if it is essential to survive. In this paper, we proposed alternatives to partially implement MC for quick adaptation of MC. The base line assumption is not to change the production lines. The pros and cons of alternatives are given by qualitative and quantitative evaluation. Especially, by giving radar chart analysis of the quantitative measures, we give insight on the changes in the business performance measures, such as time to market and cost. Proposed alternatives are based on sub-processes such as purchasing raw materials, production process changes and packaging for efficient logistics. In this way, companies are able to provide customized products with small changing of the current manufacturing system. The process and benefit of the proposed strategy is verified by real world cases of a Korean health food company.

• 복식
• /
• 제60권10호
• /
• pp.118-132
• /
• 2010

The purpose of the research is to develop a systematic model to interpret makeup signs through a case analysis of makeup shown in Alexander McQueen's ready-to-wear collections from 2001 to 2010 and to prove an importance of makeup as a communication medium to deliver social and cultural values. This research employed Panofsky's Iconology theory to analyze data. This theory consists of three steps to interpret the meaning of a work: (1) pre-iconographical description, (2) iconographical analysis, and (3) iconological interpretation. Alexander McQueen's makeup was analyzed with the three steps in order. As a result of the pre-iconographical description step, makeup styles (icons) in his collections are identified which are Egyptian style, Gothic style, Androgynous style, Victorian style, Fantasia style, and Futuristic variant style. The iconographical analysis step identified that the elements used in his makeup are inspired by his identity and life. In the final step of iconological interpretation, the researcher concluded that Alexander McQueen's makeup expresses social, cultural, and aesthetical value of the time period when the collection was created. His makeup shows postmodernism that accepts a diversity of views (the pluralism) and humanism, romantic narcissism that is his personality trait, and avant-garde that pursues a new, creative aesthetics.

• 한국정보통신학회논문지
• /
• 제2권3호
• /
• pp.309-315
• /
• 1998

본 논문에서는 직접대역확산방식을 이용한 DS-CDMA의 ISI나 ICI와 같은 문제점을 다수의 협대역 부반송파를 이용하여 해결할 수 있도록 제안된 변조방식인 MC-CDMA시스템의 성능을 분석하였다. 여기서 고려한 채널모델은 Rician 페이딩 분포를 가지며, 부반송파에서의 페이딩은 서로 독립적인 특성을 갖는 옥내이동통신 환경으로 하였다. 시스템의 성능분석을 위해 먼저 오류정정부호를 사용하지 않은 시스템의정방향과 역방향의 비트오율을 분석하였다. 그리고 (7,4) Hamming 부호, (15,7) BCH 부호, 구속장이 7인 1/2-길쌈부호와 같은 오류정정부호를 사용하였을 때 이용자수와 부반송파수 그리고 신호대 잡음비(SNR)에 따른 비트오율변화를 분석하므로써 부호화 MC-CDMA 시스템의 성능을 분석하였다.

• Journal of Communications and Networks
• /
• 제11권3호
• /
• pp.240-247
• /
• 2009

The results of performance analysis by adopting the channel scenarios characterized as Weibull fading for an multicarrierdirect sequence-coded division multiple access (MC-DS-CDMA) system are proposed in this investigation. On the other hand, an approximate simple expression with the criterion of bit error rate (BER) versus signal-to-noise ratio (SNR) method is derived for an MC-DS-CDMA system combining with maximal ratio combining (MRC) diversity based on the moment generating function (MGF) formula of Weibull statistics, and it associates with an alternative expression of Gaussian Q-function. Besides, the other point of view on the BER performance evaluation of an MC-DS-CDMA system is not only the assumption of both single-user and multi-user cases applied, but the phenomena of partial band interference (PBI) is also included. Moreover, in order to validate the accuracy in the derived formulas, some of the system parameters, such as Weibull fading parameter (${\beta}$), user number (K), spreading chip number (N), branch number (L), and the PBI (JSR) values, etc., are compared with each other in the numerical results. To the best of author's knowledge, it is a brand new idea which proposes the evaluation of the system performance for an MC-DS-CDMA system over the point of view with Weibull fading channel.

• 한국해양생명과학회지
• /
• 제3권2호
• /
• pp.96-100
• /
• 2018

간흡충(Clonorchis sinensis)은 우리나라에서 인체 감염율이 가장 높은 기생충이며, 이는 담수어류를 중간숙주로 삼는다. 따라서 강 유역에 서식하는 담수어류를 대상으로 간흡충의 메타세르카리아(Clonorchis sinensis metacercariae, CsMc)가 감염되어 있는지를 조사한 연구가 많이 수행되었으나 호수에 서식하는 물고기를 대상으로 한 연구는 거의 없다. 본 연구에서는 주요 인공호수인 소양호, 남양호, 안동호, 춘천호에서 2016년부터 2017년까지 잉어과어류를 채집하여 CsMc의 감염 여부를 조사하였다. 이생흡충류의 메타세르카리아는 남양호에서 채집한 치리 및 붕어와, 소양호에서 채집한 피라미와 끄리에서 관찰되었다. 간흡충에 특이적인 프라이머를 사용하여 PCR을 수행한 결과, 남양호의 치리에서 관찰된 것이 CsMc 이었음을 확인할 수 있었다. 본 연구는 주요 인공호수에 서식하는 잉어과어류에서 CsMc의 감염 실태에 대한 정보를 제공하고 있으며, 남양호의 치리에서 CsMc 감염을 처음으로 보고하고 있다는 것에 의의가 있다.