• 치과방사선
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• 제20권2호
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• pp.171-182
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• 1990

The purpose of this study was to investigate the effects of irradiation on the striated duct cells of the rat submandibular gland ductal tissues which control the characteristics of saliva. For this study, the experimental group was composed of 36 irradiated Sprague Dawley strain rats divided into 8 subgroups 1 hour, 2 hours, 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, 72 hours after irradiation. 4 non-irradiated rats were used as the control group. The experimental animals were singly irradiated with a dose of 18Gy gamma ray to their head and neck region by the Co-6- teletherapy unit and sacrificed after each experimental duration. The specimens were examined with a light microscope with an H-E stain and with a trans- mission electron microscope. The results of this study were as follows. In the light micrograph, a severe atrophic change occurred in the striated duct cells at 2hours after irradiation and gradual recovery occurred from 6 hours after irradiation. 2. The nuclear chromosomes of the striated duct cells were changed granular at 2 hours after irradiation. Recovery was observed at 6 hours after irradiation. Nuclear bodies were also observed from 3 hours after irradiation. 3. The mitochondria of the striated duct cells had indistinct cristae at 2 hours after irradiation, and were degenerated or swollen at 3 hours after irradiation. They recovered, however, from 6 hours, with an increasing number at 48 hours and a regular arrangement was observed at 72 hours after irradiation. 4. The microvilli showed atrophic changes at 2 hours after irradiation and were almost lost at 3 hours after irradiation. They were observed again from 48 hours after irradiation. 5. The rough endoplasmic reticulum and golgi body were not apparent at 1 hour after irradiation and were dilated with degeneration 2 hours after, but intact rough endoplasmic reticulum were observed from 3 hours after irradiation and developed well at 24 hours after irradiation. By the result of this study, showing a mild change in the functional morphology of the salivary striated duct cells immediately following irradiation, it is considered that the many complications which occur after radiation therapy, will disappear in time with the histological and the functional recovery of the glandular tissues.

• 한국산업보건학회지
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• 제29권3호
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• pp.414-419
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• 2019

Objectives: The objective of this study was to evaluate the inhibitory effect of non-thermal dielectric barrier discharge (DBD) plasma by air volume against Mycobacterium tuberculosis (MTB). Methods: Plasma generators (TB-300, Shinyoung Airtec, Seongnam-si, Korea) were operated in a 2A type biosafety cabinet. The plasma generator was set to a wind flow rate of 14 ($80m^3/h$), 18 ($110m^3/h$), and 22 ($150m^3/h$), and exposure times were set to 0 hours, 3 hours, 6 hours, 9 hours, and 24 hours. Results: The inhibitory effects of plasma at air volume 14 with prolonged exposure time of three hours was 20%, 64% at six hours, 82.3% at nine hours, and 100% after 24 hours exposure. With air volume of 18, the inhibitory effects upon plasma exposure were 36% for three hours, and 100% from 24 hours. Greater air volume resulted in greater inhibition of tuberculosis bacterial growth. In particular, the maximum inhibitory effect (100%) was shown in air volume of 22 ($150m^3/h$) after three hours of plasma exposure. Conclusions: The results showed the correlating inhibitory effects of plasma on the growth of MTB in combination with increasing plasma exposure time and air volume.

• Journal of Korean Biological Nursing Science
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• 제16권3호
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• pp.226-234
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• 2014

Purpose: This prospective study was designed to investigate the incidence of acute postoperative pain (APP) ${\geq}4$ and the risk factors of APP${\geq}$ for the first 48 hours after surgery. Methods: Data from 531 surgical patients were collected from November, 2009 to May, 2010. APP was assessed from the time of arrival at the Post Anesthetic Care Unit (PACU) to the end of the post-operative 48 hours. Risk factors of APP${\geq}$ were analyzed by logistic regression analysis. Results: The incidence of APP ${\geq}4$ was 58.8% for the first postoperative 4 hours; 33.5%, 24 hours; 11.1%, 48 hours. The score of pain was 5.55, the highest on arriving at PACU; 5.03 at postoperative 30 minutes; 4.03 at 1 hour; 3.96 at 4 hours; 2.76 at 24 hours; 1.44 at 48 hours Risk factors for APP ${\geq}4$ were females (Odds ratio [OR], 1.94; p=.013), general anesthesia (OR, 4.29; p<.001) and patient controlled analgesia (PCA) (OR, 2.83; p<.001) at 4 hours after operation; body mass index (BMI) ${\geq}25$ (OR, 1.80; p=.009), duration of surgery ${\geq}1$ hour (OR, 2.87; p=.037), general anesthesia (OR, 3.99; p<.001) and PCA (OR, 6.23; p<.001) at 24 hours; general anesthesia (OR, 3.53; p=.003) and PCA (OR, 3.01; p=.013) at 48 hours. Conclusion: Surgical patients with BMI ${\geq}25$, PCA and general anesthesia seem to have a higher incidence of pain ${\geq}4$ through the first postoperative 48 hours.

• 핵의학기술
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• 제14권1호
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• pp.138-142
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• 2010

PTH 측정은 체내 칼슘 및 이온화 칼슘의 수치와 함께 갑상선 절제술 후 저칼슘혈증을 예측하는 유용한 지표로서 임상에서는 신속한 결과 보고를 요구하고 있으나 검사반응시간이 길어 이에 상응하지 못하고 있다. 따라서 본 연구는 PTH 검사반응시간에 변화를 주어 신속한 결과 보고를 함으로서, 저칼슘혈증 예측 지표의 유용성을 평가하고자 한다. 2009년 7~8월까지 PTH를 검사한 환자들(n=131)을 대상으로 하였으며, 검사방법은 면역방사계수법으로 반응시간은 18${\pm}$2시간(Overnight), 0.5, 3, 6시간으로 구분하여 상관관계, 정밀도(10회 반복), 회수율을 측정하였다. 또한 조기 저칼슘 혈증 예측지표의 유용성을 평가하기 위해 민감도, 특이도, 양성예측도, 정확도를 비교 분석 하였다. 상관관계에서는 overnight을 기준으로 0.5시간은 $R^2$=0.987, 3시간은 $R^2$=0.993, 6시간은 $R^2$=0.996로 나타났다. 정밀도(%CV${\pm}$SD)에서 0.5시간은 $15.92{\pm}15.54$, 3시간은 $6.91{\pm}7.38$, 6시간은 $4.30{\pm}4.69$, Overnight은 $4.59{\pm}2.59$로 측정되었다. 회수율(%Mean${\pm}$SD)에서 0.5시간은 $96.8{\pm}5.44$, 3시간은 $102.6{\pm}4.35$, 6시간은 $100.7{\pm}2.56$, Overnight은 $102.2{\pm}5.98$로 측정되었다. 양성 예측치(cut-off point=15 pg/mL)를 기준으로 저칼슘혈증을 예측할 때, 0.5시간일 때 민감도 97.5% 특이도 96.0% 양성예측도 86.6% 정확도 84.7%였고, 3시간일 때 민감도 97.5% 특이도 100% 양성예측도 100% 정확도 97.5%였고, 6시간일때 민감도 97.5% 특이도 92.3% 양성예측도 92.8% 정확도 90.6%였다. Overnight법과 비교할 때 검사반응시간 3시간에서 98.3%로 가장 높은 일치율을 보였고, Kappa와 상관관계 또한 우수하였다. 이에 검사반응시간을 3시간으로 단축시켜 신속한 결과를 보고함으로써 환자의 저칼슘혈증을 조기에 예측하여 칼슘제 투여 등 적절한 조치를 취하여 환자의 증상발현을 막을 수 있는 유용한 지표로 활용될 것이다.

• 한국산업보건학회지
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• 제25권2호
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• pp.236-243
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• 2015

Objectives: This study sought to examine the association between long working hours and depressive symptoms among interns and residents in South Korea. Methods: We analyzed a cross-sectional survey of 1,661 interns and residents from the 2014 Korean Interns & Residents Survey. Total working hours during the preceding week was assessed and classified into five categories(i.e. less than 60 hours, 60-79 hours, 80-99 hours, 100-119 hours, and 120-168 hours). Depressive symptoms during the previous week were measured by using ten items from the Center for Epidemiologic Studies Depression Scale questionnaire. Multivariate negative binomial regression was applied to examine the association between long working hours and depressive symptoms after adjusting for potential confounders, including medical specialty and training year. All analyses were performed using STATA/SE version 13.0. Results: 86%(N=1,429) of interns and residents worked 60 hours or more per week. Compared to the "less than 60 hours" group, long working hours for interns and residents were significantly associated with depressive symptoms: "60-79 hours"(PR: 1.56, 95% CI: 1.05, 2.32), "80-99 hours"(PR: 2.27, 95% CI: 1.54, 3.33), "100-119 hours"(PR: 2.62, 95% CI: 1.76, 3.89), and "120-168 hours"(PR: 3.28, 95% CI: 2.21, 4.86). Conclusions: This study found that long working hours were prevalent among interns and residents in South Korea, and it was associated with depressive symptoms.

• 기본간호학회지
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• 제2권2호
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• pp.199-211
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• 1995

This study analyzed the practical education in fundamentals of nursing, for the 36 nursing schools including 12 4-year nursing schools and 24 junior college nursing schools. This survey was done from september 5th to october 5th in 1995. The results of this study were as follows : 1. Required credit in fundamentals of nursing. 1) The highest incidence of the total required credit was 7 in 4-year nursing school and 9 in junior college. 2) For the lecture course credit, the large number of 4-year nursing school gave 5 credit lessons and 6 credits provided in junior nursing colleges. 3) For the credit of practical education the major portion of 4-year nursing school gave 2 credits instruction, however junior nursing school provided 3 credits. 2. Laboratory practice in fundamentals of nursing. In laboratory practice, the ratio of instructor and student was 1 : 20 in 83.4% of the 4-year nursing school and in 66.7% of the junior nursing school. 3. Contents and hours of fundamental nursing practice. 1) In the area of health assessment and nursing process, the large number of schools allocated following hours : 6 hours for vital signs, 4 hours for nursing process, 2 hours for recording but practice for physical examination and communication was done in few schools. 2) In the area of functional health pattern, the large number of schools allocated practice hours like followings : 2 hours for I/O, 2 hours for gavage feeding, 2 hours for elimination, 6 hours for catheterization, 6 hours for bed making, 2 hours for positioning, 6 hours for personal hygiene, 2 hours for R.O.M, 4 hours for moving turning lifting, 2 hours for inhalation and suction. But C.P.R and terminally ill patient care were taught in smaller number of schools. 3) In the area of special nursing measures, the major portion of nursing schools allocated hours like followings. It consisted of 6 hours for asepsis, 16-18 hours for medication, 2 hours for heat and cold application, 2 hours for wound care. 4) 22.2% of the nursing schools had total review practice time and 36.1% of the nursing schools had the students clinical practice. Based on above mentioned results, 4-year nursing school had faithful practical education of fundamental nursing than junior nursing school. But for the contents and allocated hours for practice education, junior nursing schools were much more contents and hours than 4 year school.

• 한국가금학회지
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• 제14권1호
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• pp.55-61
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• 1987

본 시험은 broiler 사육에 있어 점등방법이 broiler 증체나 사료요구율에 미치는 영향을 구명하기 위하여 시판사료를 이용하여 1986년 4월3일부터 동년 3월 21일까지 49일간에 걸쳐 실시하였으며 broiler 감별 웅추 180수를 공시하였다. 시험구는 24시간 연속점등 방법(24L), 1시간 점등에 3시간씩 소등하는 간헐점등 방법(24L), 1시간 점증에 3시간씩 소등하는 간헐점등 방법(1L＋3D), 20시간 점등에 4시간 소등하는 방법(20L＋4D) 및 자연일조시간을 이용하는 방법(Natural)등 4개 처리하였으며 그 결과를 요약하면 다음과 같다. 1. 전시험기간중의 증체량은 1L＋3D구가 가장 높았으며, 20L＋4D구, 24L구, Natural 구 순으로 낮아졌으나 각 처리간에 유의차는 인정되지 않았다. 2. 전기 4주간의 증체량은 1L＋3D구와 20L＋4D구가 Natural구와 24L구보다 현저히 높았으나 각 추리간에 유의차는 없었다. 각 구별로는 1L＋3D구가 가장 증체량이 높았으며, 20L＋4D구, Natural 구, 24L 구 순으로 낮아졌다. 3. 후기 3주간의 증체량은 24L구, 1L＋3D구, 20L＋4D구, Natural구 순으로 낮아져서 전기와는 상이한 경향을 보였으나 각 처리간에 유의차는 없었으며 증체량도 거의 차이가 없었다. 4. 전시험기간중 사료요구율은 1L＋3D구가 가장 좋았으며, 20L＋4D구, Natural구, 24L구 순으로 나빠졌으나 각 처리간에 유의차는 인정되지 않았다. 사료섭취량은 각 처리가 거의 같은 수준을 나타내어 각 처리별 점등방법이 공시계가 충분히 사료는 섭취하는 데는 시간이 부족하지 않았음을 알 수 있었으며, 사료 섭취후 일정시간 활동을 억제하는 것이 사료요구율 개선에 좋은 영향을 미쳤음을 관찰할 수 있었다. 5. 전기 4주간의 사료요구율은 1L＋3D구와 20L＋4D구가 Natural 구와 24L구에 비하여 현저히 좋았으나 각 처리간에 유의차는 없었다. 각 구별로는 1L＋3D구가 가장 사료요구율이 좋았으며 20L＋4D구, Natural구, 24L구 순으로 나빠졌다. 6. 후기 3주간의 사료요구율은 1L＋3D구가 가장 좋았으며 24L구, 20L＋4D구, Natural구 순으로 전기와는 상이한 경향을 보였으나 각 처리간에 유의차는 없었으며 사료섭취량도 거의 차이가 나지 않았다. 이상의 결과를 종합해 볼 때 broiler에 있어 일정시간 점등과 소등을 계속하거나 일정시간 소등을 해주는 간헐점등 방법이 24시간 연속점등방법이나 자연일조시간 방법보다 증체량이나 사료요구율에 좋은 영향을 주는 것으로 사료된다.

• 대한간호학회지
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• 제22권4호
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• pp.589-603
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• 1992

This study investigated a process to estimate the need for nursing staff on the basis of a patient elassification system and the required care needs and activities. The investigation was carried out in the following four steps. Step 1. Patients were classified according to the amount of nursing care need on each shift as class I (mildly ill), class II (mederately ill), class III (acutely ill), and class IV (critically ill). Step 2. Measurement of the direct nursing care hours needed for each patient class, and measurement of indirect nursing care hourse and personal time of the nursing staff. Step 3. Calculation of he total nursing workload in a nursing unit. Step 4. Estimation of the nursing staff needed. The investigation was carried out from July 17th to 30th, during 24hours every other day. The subjects were the patients and the nursing staff on two units of Seoul National University Hospital, Korea. Some of the results from the investigation are as follows : 1) Distribution of patient classification On the neuro surgical (N.S.), the distribution was class I, 22 patient, 3, class II, 27 patients, class III, 26 patients, and class IV, 25 patients, For the orthopedic surgical unit(0.5.), it was class I, 43 patients, class II, 43 patients, class III, patients, and class IV, 3 patients. 2) Direct nursing care hours per day On the N.S. unit, 3.2 hours of direct nursing care were needed for class I, 3.9 hours for class II, 5.1 hours of class III, and 6.2 hours for class IV patients, while 2.0 hours for class I, 2.5 hours for class II, 3.5 hours for class III, 5.0 hours class IV patients were needed on the 0.5. units. 3) Analysis of direct nursing care activities Activities were classified into assessment and observation(47%), medication(38.7%), communiontion(5.1%), exercise(2.4%), elimination and irrigation(1.3%), treatmemt(1.1%), hygiene(0.8%), nutrition(0.8%), and hot and cold compress(0.1%). 4) Average hours of indirect nursing care per day. On the N.S. unit 4.2 hours, and on the O.S. unit, 3.5 hours of RN indirect care was needed. 5) The average personal time used by the of nursing staff was 17 minutes for both RNs and nursing assistants in the N.S. unit, and 32 minutes for both RNs and nursing assistants in the O.S. unit. 6) Estimation of nursing staff needed on two specialized units of a university hospital For the N.S. nursing unit of 43 beds, 31 nursing staff would be indicated. For the 0.5. nursing unit of the same number of beds, 19 nursing staff would be indicated.

• 대한치과교정학회지
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• 제23권2호
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• pp.199-216
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• 1993

The purpose of this study was to quantify the biologic effects of the tensile forces from helical springs across the maxillary incisors on the periodontal tissues of rats. 39 Sprague-Dawlely rats were divided into a control group(3 rats) and three experimental groups(36 rats)-group 1, pressured with a light force(50-75g), group 2, with a heavy force(250-300g) and group 3, with a hen force(250-300g) plus laser irradiation. Autoradiographic and histopathologic observations were performed in 12, 24, 48 and 96 hours after force application. The result were as follow : 1. Hyalinized zone of periodontal ligament began to appear at pressure side in 12 hours in group 2 and group 3 ; all decreased in 96 hours except in group 2. 2. Alveolar bone resorption began to appear in 12 hours in group 2 and group 3 ; Group 2 showed more resorption than group 1 and no difference to group 3. 3. Tearing of periodontal ligament and vascular dilatation began to appear at tension side in 12 hours in all groups ; Group 2 showed more changes than group 1 and no difference to group 3 ; Decrease began to appear in 96 hours. 4. New bone formation began to appear at tension side in 12 hours and increased more and more ; No differences were shown of groups 5. New capillary proliferation began to appear at pressure side in 12 hours ; The changes were the greatest in group 3, group 2, group 1, in that order. 6. Positive reaction of cells to $[^3H]-thymidine$ was the greatest in 24 hours of all groups and decreased with times i Group 2 showed more reaction than group 1 and no difference to group 3.

• 수산해양기술연구
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• 제58권3호
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• pp.205-213
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• 2022

The experimental fish transplanted from China in 2015 was used after seedling production and cultivated. Breeding management for experiment was carried out from October 2020 to February 2021. Also, it succeeded in inducing artificial maturation three to four months earlier than wild broodstock and secured good quality fertilized eggs. The average size of fertilized eggs was 1.22 mm, at 20℃ Blastodisc (15 minutes post-fertilization), 2 cell (50 minutes), 4 cell (1 hours), 8 cell (2 hours), 16 cell (2 hours and 30 minutes), 32 cell (2 hours and 50 minutes), morula (3 hours), blastula (8 hours), gastrula (15 hours), skull formation (20 hours), organ formation (30 hours) and hatching yolk larvae stage (35 hours). The total length of the just hatched larvae were 2.50 ± 2 mm, and then gain growth of 42.5 mm by 60 days, reaching 45 ± 5 mm.