• Natural Product Sciences
• /
• v.25 no.2
• /
• pp.115-121
• /
• 2019

Alzheimer's disease is a chronic neurodegenerative disorder with no curative treatment. The commercially available drugs, which target acetylcholinesterase, are not satisfactory. The aim of this study was to investigate the cholinesterase inhibitory activity of Solenostemma argel aerial part. Eight compounds were isolated and identified by NMR: kaempferol-3-O-glucopyranoside (1), kaempferol (2), kaempferol-3-glucopyranosyl($1{\rightarrow}6$)rhamnopyranose (3) p-hydroxybenzoic acid (4), dehydrovomifoliol (5), 14,15-dihydroxypregn-4-ene-3,20-dione (6), 14,15-dihydroxy-pregn-4-ene-3,20-dione-$15{\beta}$-D-glucopyranoside (7) and solargin I (8). Two of them (compounds 2 and 3) could inhibit over 50 % of butyrylcholinesterase activity at $100{\mu}M$. Compound (2) displayed the highest inhibitory effect against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with a slight selectivity towards the latter. Molecular docking studies supported the in vitro results and revealed that (2) had made several hydrogen and ${\pi}-{\pi}$ stacking interactions which could explain the compound potency to inhibit AChE and BChE.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.21 no.2
• /
• pp.91-100
• /
• 2011

The Triple Data Encryption Algorithm (Triple DES) is an international standard of block cipher, which composed of two encryption processes and one decryption process of DES to increase security level. In this paper, we proposed a Differential Fault Analysis (DFA) attack to retrieve secret keys using reduction of last round execution for each DES process in the Triple DES by fault injections. From the simulation result for the proposed attack method, we could extract three 56-bit secret keys using exhaustive search attack for $2^{24}$ candidate keys which are refined from about 9 faulty-correct cipher text pairs. Using laser fault injection experiment, we also verified that the proposed DFA attack could be applied to a pure microprocessor ATmega 128 chip in which the Triple DES algorithm was implemented.

• Journal of the Korean Society of Costume
• /
• v.19
• /
• pp.175-194
• /
• 1992

Le Proche-Orient est le pays de la Bible, Le peuple He breu ancien, appartenant la race des S mits s mi-nomades, est venu avec Abraham, de m sopotamie en Palestine, terre de Canaan. Nous avons consid r les v tements du peuple des anciens H breux en nous basant sur la Bible et en observant des peintures murales et des bas-reliefs des divers payes de l'ancienne poque, Pour comprendre l' volution des v tements des gens de la pr sente r gion palestinienne, nous avons tudi les v tements traditionnels de la race b douine qui m nent jusqu' maintenant une vie nomade dans le m nent jusqu' maintenant une vie nomade dans le d sert, parce que nous n'avons pas pu connaitre le processus d' volution des v tements apr s l'ancienne poque la suite d' v nements historiques compliques. En conclusion, nous pouvons nous r sumer comme suit: 1) Nous pensons que la kimlah, costume important du peuple h breu ancien est devenu abajeh, manteau des B douins, puisque ces v tements servent prot ger le corps lors des changments de temps, et la nuit on les utilise comme couverture et comme sac pour y mettre des objets, et comme tente lors su travail. en un mot, les fonctions de la Simlah et celles de l'abajeh sont les memes l' poque ancienne et maintenant. 2) Nous pensons que la forme et l'utilisation de la Kethoneth ayant une forme de tunique et de la thob des B douins sont presque semblable. La kethoneth et la thob sont la tuniqu importante que portent jusqu' maintenant tous les peuples du Proche-Orient. 3) Comme on le voit dans la Bible, les femmes du peuple h breu et celles des B douins utilisent le voile pour couvrir la e te, et se servent d'accessoires pour d corer leur corps. A l'avenir, les vVtements des Palestiniens, dans une recherche pous approfondie, feront l'objet de a 2 me partie de l' tude des costumes du Proche-Orient.

• Journal of Practical Agriculture & Fisheries Research
• /
• v.22 no.1
• /
• pp.65-77
• /
• 2020

In order to industrialize of Dendranthema indicum (L.) DesMoul., which is a lot of commercially available and is synonymous with chrysanthemum tea, in the autumn of 2018, Dendranthema indicum (L.) DesMoul. seeds were collected from its own native region, and the seeds were germinated after refrigerated storage. Young seedlings were subjected to experiments in February, March, and April in the open field to examine the effects on the harvesting of leaves by distance and the growth of leaves and stems. The results of analyzing the components by collecting the leaves+stem after collecting the flower of Dendranthema indicum (L.) DesMoul. are as follows. 1. When D. indicum (L.) DesMoul. seedlings were planted according to the transplanting date, the number of flowers was 17.1 in the transplanting date in April. The diameter of the flower was 2.9cm, 16ea, 6.5~6.6g in the fresh weight, and the dry weight of the case was 1.1~1.2g. The leaves were 46~47ea in March and April in the planted area, 5.2~5.3cm in leaf length and 3.5~3.6cm in leaf width. 2. When planted D. indicum (L.) DesMoul. seedlings according to transplanting distance, the number of flowers was 16.2 when planted at 20×20cm intervals and, 16.8~17.1 at 30×30~50×50cm intervals. The diameter of the flower was 2.7~2.8cm, the number of petals was 8, the length of the petal was 0.8 cm, and fresh weight was 6.5~6.6g per flower. Leaves had the largest number of 47 of 30×30cm and 40×40cm, and leaf length appeared at the longest 6.2cm in the 50×50cm treatment area, but 5.2cm in the other treatment areas. 3. The extraction yield of D. indicum (L.) DesMoul. leaves+stems was 7.93%, and the extraction solvent colors were light green at 50, 60% and green at 70, 80, 90, 100%. The extraction yield of D. indicum (L.) DesMoul. flowers was 7.58%, the color of the extraction solvent was light yellow at 50, 60 and 70%, yellow at 80 and 90%, and dark yellow at 100%. 4. We confirmed 11 kinds of ingredients such as in D. indicum (L.) DesMoul. flowers are gallic acid, 4-hydroxy benzoic acid, methyl gallate, 4-hydroxy-3-methoxy benzoic, caffeic acid, salicylic acid, p-coumaric acid, sinapic acid, naringin, 4-melthoxyben, flavone. The content was 29.200-36.900ppm. 5. The components contained in the D. indicum (L.) DesMoul. leaf+stem, salicylic acid appeared at 6,129.526ppm, and the next 4-methoxyben was 1,966.714ppm. It was methyl gallate 8.197ppm, 4-hydroxy-3-methoxy benzoic 6.994ppm, caffeic acid 5.566ppm, flavone 4.522ppm, p-coumaric acid 3.787ppm, gallic acid 1.893ppm that appeared in the content below 10ppm.

• Proceedings of the Korean Magnestics Society Conference
• /
• 2008.12a
• /
• pp.205.1-205.1
• /
• 2008

• Membrane and Water Treatment
• /
• v.11 no.2
• /
• pp.123-130
• /
• 2020

Submerged Membrane bioreactor (SMBR) is one of the last techniques that allow a high quality of treated industrial effluents by coupling biological treatment and membrane separation. Thus, this research was an effort to evaluate performance of a SMBR treating a model textile wastewater (MTWW). Different SMBR operating parameters like mixed liquor suspended solids (MLSS) and Dissolved oxygen concentration, hydraulic retention time (HRT), and nutrients addition (N and P) have been investigated. MTWW (influent to the SMBR) was generated using the reactive azo-dye, Novacron blue FNG (100mg/L feed concentration). Results of MTWW treatment using SMBR under optimal operating conditions (MLSS, 4.2-13.3g/L; HRT, 4 days; pH, 6.9-7.2; conductivity, 400-900 μS/cm and temperature, 19.4-22.2 ℃) showed that COD and blue colour treatment performances are between 94-98% and 30-80%, respectively. It is concluded that SMBR can be used in large scale textile wastewater treatment plants to improve effluent quality in order to meet effluent discharge standards.

• Proceedings of the Korean Magnestics Society Conference
• /
• 2012.11a
• /
• pp.100-100
• /
• 2012

• The Korean Journal of Quaternary Research
• /
• v.2 no.1
• /
• pp.1-11
• /
• 1988

L'analyse des galets fractures decouverts sur les sols d'habitat de la grotto du Lazaret permet de penser que la cassure des galets se serait produite sur place dans la grotte, soit par des actions naturelles, soit par des actions des hommes prehistoriques. D'apres la comparaison des resultats obtenus par 1'etude exprimentale, les cassures des galets sont liees a plusieurs modes de fraturation. On peut seulement dire que les trois modes (1,3 et 5) sont susceptibles de donner des indications sur 1'aspect intentionnel de certains types de fracturation.

• The KIPS Transactions:PartC
• /
• v.9C no.2
• /
• pp.157-162
• /
• 2002

In this study, the secure Internet phone system using digital signature and data encryption with DES algorithm and EDE algorithm was implemented. And new key distribution algorithm was suggested utilizing the Diffie-bellman algorithm. For reducing processing time, a table combined with S-BOX and P-BOX of the DES was used. The proposed system was implemented with Java and the results showed the processing time using DES algorithm for encryption was 1.46 seconds and that of EDE algorithm was 3.25 seconds respectively. This system can be applied to Protect the copyright of sound products and data using internet.

• Journal of Food Hygiene and Safety
• /
• v.5 no.4
• /
• pp.179-186
• /
• 1990

This study was performed for assessing carcinogenicity of several synthetic hormones; Diethylstilbesterol (DES), 17-ethinylestradiol ($EE_2$) and Bovine somatotrophin (BST). Six weeks old F344 rats were divided into five groups and given an intraperitoneally injection of 200 mg of diethylnitrosamine (DENA). At two week after beginnig of experiment, DES, $EE_2$, BST. Phenobarbital were administered to group 1, 2, 3 and 4 respectively, group 4 is positive control and group 5 is negative control. At the same time, all groups received a single i.p. injection of D-galactosamine at a dose of 300 mg/kg and underwent 2/3 partial hepatectomy at week 5. All rats were sacrificed at the end of week 8 for assessment of liver lesion development. The liver was processed for immunohistochmical staining for GST-P and quantitatively analyzed by image analyzer. It was concluded that two synthetic estrogen hormones (DES, $EE_2$) was different significantly (p < 0.01) but BST was not different as compared with control group. Therefore, we thought that DES, $EE_2$ was promoting effects and BST was not in rat hepatocarcinogenesis.