• Journal of the East Asian Society of Dietary Life
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• v.22 no.2
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• pp.224-230
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• 2012

To investigate the effect of Panax ginseng C.A. Meyer extract (Ginseol K-b1), on skin functionality, we evaluated skin appearance and properties, such as wrinkle formation, skin moisture content, and skin elasticity in the skin of hairless mice damaged by UV irradiation. In addition, the effect of Ginseol K-b1 on collagen synthesis in human dermal fibroblasts was investigated. Female hairless mice were orally administered Ginseol K-b1 for 10 weeks with UV irradiation. Wrinkle formation in the Ginseol K-b1-treated group was significantly suppressed compared to the UV-irradiated group. Skin properties, including skin moisture content and elasticity, of the Ginseol K-b1-treated group were better than those of the control group. In the human fibroblast cells, Ginseol K-b1 treatment enhanced cell proliferation and significantly stimulated collagen synthesis. These results suggest that Ginseol K-b1 is a potent ingredient with anti-aging effects.

• Geomechanics and Engineering
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• v.34 no.3
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• pp.233-250
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• 2023

This paper investigates the flexural analysis of isotropic, transversely isotropic, and laminated composite plates using a new higher-order normal and shear deformation theory. In the present theory, only five unknown functions are involved compared to six or more unknowns used in the other similar theories. The developed theory does not need a shear correction factor. It can satisfy the zero traction boundary conditions on the top and the bottom surfaces of the plate as well as account for sufficient distribution of the transverse shear strains. The thickness stretching effect is considered in the computation. A simply supported was considered on all edges of the plate. The plate is subjected to uniform and sinusoidal distributed load in the static analysis. Laminated composite, isotropic, and transversely isotropic plates are considered. The governing equations are obtained utilizing the virtual work principle. The differential equations are solved via Navier's procedure. The results obtained from the developed theory are compared with other higher-order theories considered in the previous studies and 3D elasticity solutions. The results showed that the proposed theory accurately and effectively predicts the bidirectional bending responses of laminated composite plates. Several parametric studies are presented to illustrate the various parameters influencing the static response of the laminated composite plates.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.2
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• pp.515-527
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• 2014

This study conducted experiment for understanding engineering characteristics of domestic sands by examining standard sand and sand from Yokji Island and Nakdong River in terms of confining pressure, $K_0$, over consolidation and relative density factors through triaxial compression test. The test showed that deviator stress by strain positively changed as confining pressure and relative density grow while $K_0$ and over consolidation factors do not directly correlated with it. Angle of internal friction decreases as confining pressure increases which strengthens contact force between particles, and declines as relative density drops, whereas $K_0$ and over consolidation factors hardly affect the results. When it comes to volumetric strain, volume expansion decreases as confining pressure increase due to crushability and rearrangement of particles while $K_0$ and over consolidation shows same movement unconditionally, and relative density appears compressed as it grows at the beginning however it expands as axial strain increases. Modulus of elasticity ($E_{sec}$) by strain has tendency into convergence resulting in initial secant modulus of elasticity ($E_{ini}$) > secant modulus of elasticity($E_{sec}$) > tangent modulus of elasticity ($E_{tan}$). On the other hand, it grows as confining pressure and relative density increase while indicating similar modulus of elasticity ($E_{sec}$) regarding on $K_0$ and over consolidation. Slope of critical line (M) tended to decrease as confining pressure increases, follow same line according to $K_0$, confining pressure and relative density, and increase as relative density grows.

• Structural Engineering and Mechanics
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• v.66 no.5
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• pp.665-676
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• 2018

In this study, a four-node quadrilateral partial mixed plate element with low degrees of freedom (dofs) is developed for static and free vibration analysis of functionally graded material (FGM) plates rested on Winkler-Pasternak elastic foundations. The formulation of the presented finite element model is based on a parametrized mixed variational principle which is developed recently by the first author. The presented finite element model considers the effects of shear deformations and normal flexibility of the FGM plates without using any shear correction factor. It also fulfills the boundary conditions of the transverse shear and normal stresses on the top and bottom surfaces of the plate. Beside these capabilities, the number of unknown field variables of the plate is only six. The presented partial mixed finite element model has been validated through comparison with the results of the three-dimensional (3D) theory of elasticity and the results obtained from the classical and high-order plate theories available in the open literature.

• BMB Reports
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• v.49 no.12
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• pp.655-661
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• 2016

Polymer brush is a soft material unit tethered covalently on the surface of scaffolds. It can induce functional and structural modification of a substrate's properties. Such surface coating approach has attracted special attentions in the fields of stem cell biology, tissue engineering, and regenerative medicine due to facile fabrication, usability of various polymers, extracellular matrix (ECM)-like structural features, and in vivo stability. Here, we summarized polymer brush-based grafting approaches comparing self-assembled monolayer (SAM)-based coating method, in addition to physico-chemical characterization techniques for surfaces such as wettability, stiffness/elasticity, roughness, and chemical composition that can affect cell adhesion, differentiation, and proliferation. We also reviewed recent advancements in cell biological applications of polymer brushes by focusing on stem cell differentiation and 3D supports/implants for tissue formation. Understanding cell behaviors on polymer brushes in the scale of nanometer length can contribute to systematic understandings of cellular responses at the interface of polymers and scaffolds and their simultaneous effects on cell behaviors for promising platform designs.

• Structural Engineering and Mechanics
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• v.28 no.2
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• pp.239-257
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• 2008

Double-sided punched metal plate timber fasteners present projections on both sides, which offer improved joint fire resistance and better joint aesthetics. In this paper, 3-D nonlinear finite element models were developed to simulate double-sided nail plate fastener timber joints. The models, incorporating orthotropic elasticity, Hill's yield criterion and elasto-plasticity and contact algorithms, are capable of simulating complex contact between the tooth and the timber and between the base plate and the timber in a fastener. Using validated models, parametric studies of the double-sided nail plate joints was undertaken to cover the tooth length and the tooth width. Optimal configuration was assumed to have been attained when increase in nail plate tooth width did not result in a raise in joint capacity, in conjunction with the optimum tooth length. This paper presents the first attempt to model and optimise tooth profile of double-sided nail plate fastener timber joints, which offers rational designs of such fasteners.

• Coupled systems mechanics
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• v.7 no.1
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• pp.5-25
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• 2018

A fully-coupled thermodynamic-based transient finite element formulation is proposed in this article for electric, magnetic, thermal and mechanic fields interactions limited to the linear case. The governing equations are obtained from conservation principles for both electric and magnetic flux, momentum and energy. A full-interaction among different fields is defined through Helmholtz free-energy potential, which provides that the constitutive equations for corresponding dual variables can be derived consistently. Although the behavior of the material is linear, the coupled interactions with the other fields are not considered limited to the linear case. The implementation is carried out in a research version of the research computer code FEAP by using 8-node isoparametric 3D solid elements. A range of numerical examples are run with the proposed element, from the relatively simple cases of piezoelectric, piezomagnetic, thermoelastic to more complicated combined coupled cases such as piezo-pyro-electric, or piezo-electro-magnetic. In this paper, some of those interactions are illustrated and discussed for a simple geometry.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.44 no.1
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• pp.70-73
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• 1999

This study was conducted to ascertain the chromosomal locations and effect of quantitative trait loci (QTL) associated with the physical traits of rice (Oryza sativa L.) eating quality. One hundred sixty four recombinant inbred lines (MGRILs) of F$_{11}$ were derived from the cross between Milyang 23 (Tongil type) and Gihobyeo (japonica type). They were evaluated for six physical traits of cooked rice. Transgressive segregation was observed for all examined traits. Significant QTL were detected (LOD$\geq$2.0) in three traits, including single QTL for adhesiveness, gumminess, and chewiness of cooked rice, respectively. Phenotypic variation explained by each QTL ranged from 6.3% to 14.6%. However, no significant QTL was detected for hardness, cohesiveness, and elasticity of cooked rice. Pleiotropic effects of single QTL on different traits are observed.d.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.10 no.6
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• pp.56-62
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• 2011

In this study, a method for the press forming of rectangular aluminium tube has been proposed. Rectangular aluminium tube has high stiff as the cold steel which can be lighter over 30% weight. It is increased every year by being recycled over 80%. Press die consists of punch, wing-die and holder for aluminium tube bending. When punch is applied with aluminium tube, holder is operated as same punch and wing-die is rotated through hinge. Stress-strain relations and springback are considered by bending angle of aluminium tube. In this study, the behaviors on tubes of square aluminium and rectangular aluminium with different thickness and area are established by the analysis of $DEFORM^{TM}$-3D program. Reducing fuel consumption is expected by using the aluminium tube deformation and it becomes the lightweight through recycling.

• Proceedings of the KIEE Conference
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• 2002.06a
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• pp.67-71
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• 2002

In this paper, we propose a new deformable model based on non-linear elasticity, anisotropic behavior and the finite element method and developed the high-speed controller for haptic control. The proposed controller is based on the PCI/FPGA technology, which can calculate the real position and transmit the force data to device rapidly, The haptic system is composed of 6DOF force display device, high-speed controller and HIR library for 3D graphic deformation algorithm & haptic rendering algorithm. The developed system will be used on constructing the dynamical virtual environment. we demonstrate the relevance of this approach for the real-time simulating deformations of elastic objects. To show the efficiency of our system, we designed simulation program of force-reflecting, As the result of the experiment, we found that the controller has much higher resolution than some other controllers.