• 대한기계학회논문집B
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• 제36권3호
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• pp.259-268
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• 2012

엇갈리게 배열된 두 개의 수평관의 수직 이격거리($P_v$/D)와 수평 이격거리($P_h$/D)를 변화시키며 자연대류 열전달을 실험적으로 측정하였다. 열/물질전달의 상사성을 이용하여 물질전달 실험을 수행하였고 난류영역까지 확장하였다. Pr 수 2,014, RaD 수 $1.5{\times}10^8\sim2.5{\times}10^{10}$, $P_v$/D는 1.02~5, $P_h$/D는 0~2 범위에서 수행하였다. 하단 수평관의 물질전달은 단일 수평관 상관식의 예측치와 일치하였다. 상단 수평관의 물질전달은 $P_v$/D가 작을 때, 하단 수평관에서 상승하는 플룸의 예열영향(Preheating effect)으로 인해 감소하였고, $P_h$/D가 증가하면 급격히 상승하였다. 그러나 $P_v$/D가 클 때, 상단 수평관의 물질전달은 하단 수평관의 플룸 속도영향으로 인하여 단일 수평관보다 컸고, $P_h$/D가 증가함에 따라 완만하게 감소하였다. $P_h$/D가 매우 증가하여도 굴뚝효과(Chimney effect)와 측면유동효과(Side flow effect) 인하여 상단 수평관의 열전달이 하단 수평관의 열전달보다 크게 나타났다.

• 한국수자원학회논문집
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• 제45권5호
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• pp.465-472
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• 2012

최근water front나 자연형 하천의 개발이 많아지는 가운데 해안에 인접한 하천설계에 있어 일반적으로 기점 홍수위가 만조 시 수위보다 높게 계산되면 조석의 영향을 고려하지 않고 기점 홍수위만으로 수리해석을 하는 경우가 대부분이다. 그러나 본 연구는 기점 홍수위가 만조 시 수위 보다 높더라도 밀려오는 조류의 영향으로 하천 기점 홍수위의 변화를 야기시킬 수 있을 것이라 판단하여 부산의 지방하천인 온천천이 조석현상에 의해 어떤 흐름의 변화가 발생하는지를 Delft-3D를 이용하여 분석하였다. 수치해석 결과 하류 경계조건에 조석영향을 고려하였을 경우 하천의 일정범위까지 수위가 조석의 주기성을 나타내었고 하천 상류방향으로 수위 변동범위가 확대되었다.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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• 제5B권2호
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• pp.123-128
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• 2005

This paper presents an analysis of the permanent magnet overhang effect for the permanent magnetic actuator. Generally, the overhang is often used to increase the force density in permanent magnet machineries. The overhang is particularly profitable in reducing the volume after increasing the force density per volume when using the overhang effect of the permanent magnet. Therefore, the 3D Equivalent Magnetic Circuit Network Method (3D EMCN) has been used in this paper. According to the plunger position, the flux distribution per overhang length and the holding force are quantitatively compared. Furthermore, an appropriate length of the overhang has been proposed. To confirm the accuracy of the analysis method, the results of 2D FEM and 3D FEM are compared for the basic model.

• 한국해양공학회지
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• 제25권2호
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• pp.29-35
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• 2011

In order to effectively control waves in a coastal zone, Multi-Cylinder Piles have been suggested as economic structures. A numerical analysis was conducted using the Delft-3D: WAVE module based on SWAN, which considered wave shoaling and refraction. Moreover, irregular waves were used to investigate the hydrodynamic characteristics of the wave interaction with the structure. In this paper, a numerical analysis was carried out to research the effect of wave control through a wave height analysis concerning an existing, concrete wave breaker and multi-cylinder piles placed at the same location. As a result, the effect of the wave control is shown using the wave breaker, multi-cylinder piles, and existing data.

• 혜화의학회지
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• 제26권1호
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• pp.81-87
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• 2017

이 증례보고의 목적은 도침 시술이 외상성으로 유발된 급성 요배통 환자의 통증, 기능, 삶의 질에 미치는 영향을 보고하기 위함이다. 1주일 이내의 외상성 계기로 인해 요배통을 호소하는 총 3명의 환자에게 도침 시술을 시행하여 NRS, ROM, RMDQ, EQ VAS에서 유의한 호전이 있었으며 EQ-5D의 경우 증례 1,3에서 유의한 호전이 있었다. 향후 보다 많은 증례보고 및 연구가 필요할 것으로 사료된다.

• 한국미생물·생명공학회지
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• 제24권2호
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• pp.137-142
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• 1996

The biosynthesis and catabolite repression of cyclodextrin glucanotransferase(CGTase) and cyclodextrinase(CDase) were studied in Bacillus sp. KJI6. In accompanying to the cell growth, CGTase was synthesized during early growth phase (20h culture) and CDase was synthesized during late growth phase (60h culture). Synthesis of CGTase was rather constitutive than that of CDase in the absence or presence of carbon source. Production of CDase was strongly stimulated by amylopectin and $\gamma$-CD medium (about 6 times), but CGTase synthesis was slightly increased (about 1.3 times). Easily metabolizable carbohydrates such as D-glucose, D- fructose and D-mannose completely repressed the expression of CDase, whereas their repressive effect to CGTase synthesis was relatively negligible. By addition of 10 mM cAMP, any significant effect on the synthesis of the two enzymes was not observed. Hardly metabolizable glucose analogues such as 2-deoxy-D-glucose and 3-0-methyl-D-glucopyranose also did not show any repression on the syntheses of CGTase and CDase. This indicates that D-glucose has to be metabolized to exert its repressive effect. With these results, it seems likely that the biosynthesis of CGTase and CDase are regulated by the catabolite repression due to unknown metabolite(s) of EM pathway.

• 약학회지
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• 제40권4호
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• pp.428-437
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• 1996

The in vitro and in vivo antibacterial activities of a new fluoroquinolone, DWP20364(1-cyclopropyl-5-amino-6,8-difluoro-7-(2,7-diazabicyclo[3.3.0]oto-4-ene-7-yl)-1 ,4-di-hydro-4-oxoquinoline-3-carboxylic acid) were evaluated in comparison with those of ciprofloxacin(CPFX), sparfloxacin(SPFX) and ofloxacin(OFLX). DWP20364 was more potent than CPFX and OFLX against Staphylococcus spp., Streptococcus spp. and Enterococcus faecium MD8b and it was similarly or slightly less active than CPFX against Escherichia spp. and Pseudomonas spp.. For MRSA and OFLX resistant strains (Staphylococcus spp.(14),Enterococcus spp.(4), Acinetobacter spp.(2), Pseudomonas spp.(9), Klebsiella spp.(2) and Serratia spp.(6)),DWP20364(MICs for 90% of strains,0.025 and 12.5${\mu}$g/ml, respectively) was 4 to 32 folds more potent than SPFX and CPFX. The activity of DWP20364 decreased moderately in the presence of 5mM $Mg^{2+}$. However, various pHs and the concentrations of various serum had no effect on the activity of DWP20364. DWP20364 possessed a bacteriocidal effect at the 1MIC against gram positive and gram negative strains. The protective effect of DWP20364 against systemic infections in mice caused by S. aureus Smith or S. aureus L2379 was superior to that of CPFX and SPFX but it was less active than that of CPFX against infection by P. aeruginosa E-2.

• 대한한의학회지
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• 제23권1호
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• pp.120-132
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• 2002

Objectives : The purpose of this investigation was to evaluate the effect of Goomicheongsim-won Extracts on E20 corticells and P7 cerebellar cells exposed to hypoxia, and the effect on neuronal protection by elimination of Rhinoceros unicornis L. and/or Orpiment $As_2S_3$. Methods : P7 cerebellar cells were grown in various concentrations of KM-A, KM-B, KM- C and KM-D. On 7 DIV (day in vitro), cells were exposed to hypoxia (98% $N_2/5%{;}CO_2,{\;}3{\;}hr,{\;}37^{\circ}C$) and normoxia, and then further incubated for 3 days. Neuronal viabilities were expressed as percentages of control. E20 cortical cells were grown in various concentrations of KM-A, KM-B, KM-C, and KM-D. On 7 DIV, cells were exposed to hypoxia and normoxia, and then further incubated for 3 and 7 days. Results : I. The effect of KM-A on neuronal protection was significantly increased P7 cerebellar granule cells and E20 cortical cells on normoxia and hypoxia. 2. The effect of KM-B on neuronal protection was increased P7 cerebellar granule cells on normoxia, but was significantly decreased P7 cerebellar granule cells on hypoxia. The effect of KM-B on neuronal protection was non-significantly increased E20 cortical cells on normoxia and hypoxia. 3. The effect of KM-C on neuronal protection was non-significantly increased P7 cerebellar granule cells on normoxia and hypoxia and was decreased (p=0.058) on hyperconcentration of the extracts in normoxia. The effect of KM-C on neuronal protection was significantly increased P7 cerebellar granule cells and E20 cortical cells on normoxia and hypoxia (10 DIV), and the effect was E20 cortical cells on normoxia (14 DIV), non-significantly increased E20 cortical cells on hypoxia (14DIV). 4. The effect of KM-D on neuronal protection was increased P7 cerebellar granule cells on normoxia but was not on hyperconcentration of the extracts, was significantly decreased on hyperconcentration of the extracts in hypoxia. The effect of KM-D on neuronal protection was significantly increased E20 cortical cells on normoxia and was significantly increased E20 cortical cells increased on hypoxia (10 DIV). Conclusions : Goomicheongsim-won extracts had applicable effect on E20 corticells and P7 cerebellar cells exposed to hypoxia. The effect on neuronal protection by elimination of Rhinoceros unicornis L. and/or Orpiment $As_2S_3$ was changed.

• 한국방사선학회논문지
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• 제16권4호
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• pp.427-434
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• 2022

심방세동 치료는 3D장비를 이용한 고주파 절제술과 냉각 풍선을 이용한 냉각 풍선 절제술이 있다. 두 시술 모두 혈관 조영 장비를 이용해 심장의 구조를 파악한 뒤 진입하는 공통점이 있다. 따라서 시술 시간에 따른 피폭의 영향이 환자와 시술자 모두 위협이 될 수 있다는 단점이 존재하므로 본 연구를 통해 총 절제술 시간과 방사선 피폭 영향 등의 연관성을 확인하고자 한다. 2019년 03월부터 2022년 07월까지 관상 동맥 조영술과 부정맥 시술을 동시에 시행한 41명 환자의 후행적 데이터를 이용하였다. 총 절제술 시간에 대한 범위는 절제술 시작 시점부터 종료 시점까지의 기록된 데이터를 대상으로 하였다. 3D 고주파 절제술 종료 시점은 4곳의 폐정맥에 대해 절제술 시행을 완료한 시점으로 하였고 냉각 풍선 절제술의 경우 전기적 절연에 성공한 데이터를 대상으로 하였다. 총 절제술에 걸린 시간을 분석한 결과 냉각 풍선 절제술에 걸린 시간이 1037.29±103.66 s로 3D를 이용한 고주파 절제술 3485.9±405.71 s 보다 2448.61 s 더 빠른 시술 시간을 보였고 통계적으로 유의했다. (p<0.05) 총 투시 조영 시간을 분석한 결과 3D를 이용한 고주파 절제술 피폭 시간이 2573.75±239.08 s로 냉각 풍선 절제술 피폭 시간 4290.9±420.42 s 보다 1717.15 s만큼 덜 노출됐으며 통계적으로 유의했다. 총면적 선량의 경우 3D 고주파 절제술이 59.04±13.1 uGy/m²로 냉각 풍선 절제술 980.6±658.07 uGy/m²보다 921.56 uGy/m²만큼 저 선량을 나타냈으며 통계적으로 유의했다. 냉각 풍선 절제술의 절연 시간이 3D 고주파 절제술보다 짧은 것으로 보아 환자의 상태가 좋지 않아 빠른 시술이 필요한 경우 냉각 풍선 절제술을 이용하는 방법이 효과적일 것으로 판단된다. 그러나 심방세동이 오래된 환자일 경우 심장의 구조적 변화가 발생할 확률이 높으므로 조작이 어려운 냉각 풍선 절제술 보다 3D 고주파 절제술을 이용해 치료하는 방법이 좋을 것으로 사료된다.

• 생약학회지
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• 제32권1호통권124호
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• pp.68-71
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• 2001

For the use of tannins in the whitening-effect cosmetics, inhibitory effect against tyrosinase activity was determined. Three condensed tannins including gallocatechin, gallocatechin 3',4'-di-O-gallate and epicatechin 3-O-gallate and three hydrolyzable tannins, 1,2,6-tri-O-galloyl-${\beta}$-D-glucose, 2,3-(S)-HHDP-D-glucose and pedunculagin showed 15-29% mild inhibitory effects against tyrosinase activity.