• Progress in Medical Physics
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• v.33 no.4
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• pp.80-87
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• 2022

Purpose: Proton therapy has different relative biological effectiveness (RBE) compared with X-ray treatment, which is the standard in radiation therapy, and the fixed RBE value of 1.1 is widely used. However, RBE depends on a charged particle's linear energy transfer (LET); therefore, measuring LET is important. We have developed a LET measurement method using the inefficiency characteristic of an EBT3 film on a proton beam's Bragg peak (BP) region. Methods: A Gafchromic EBT3 film was used to measure the proton beam LET. It measured the dose at a 10-cm pristine BP proton beam in water to determine the quenching factor of the EBT3 film as a reference beam condition. Monte Carlo (MC) calculations of dose-averaged LET (LET_d) were used to determine the quenching factor and validation. The dose-averaged LETs at the 12-, 16-, and 20-cm pristine BP proton beam in water were calculated with the quenching factor. Results: Using the passive scattering proton beam nozzle of the National Cancer Center in Korea, the LET_d was measured for each beam range. The quenching factor was determined to be 26.15 with 0.3% uncertainty under the reference beam condition. The dose-averaged LETs were measured for each test beam condition. Conclusions: We developed a method for measuring the proton beam LET using an EBT3 film. This study showed that the magnitude of the quenching effect can be estimated using only one beam range, and the quenching factor determined under the reference condition can be applied to any therapeutic proton beam range.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.119-120
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• 2002

The aim is to urge the need of elaborate commissioning of 3D RTP system from the firsthand experience. A 3D RTP system requires so much data such as beam data and patient data. Most data of radiation beam are directly transferred from a 3D dose scanning system, and some other data are input by editing. In the process inputting parameters and/or data, no error should occur. For RTP system using algorithm-bas ed-on beam-modeling, careless beam-data processing could also cause the treatment error. Beam data of 3 different qualities of photon from two linear accelerators, patient data and calculated results were commissioned. For PDD, the doses by Clarkson, convolution, superposition and fast superposition methods at 10 cm for 10${\times}$10 cm field, 100 cm SSD were compared with the measured. An error in the SCD for one quality was input by the service engineer. Whole SCD defined by a physicist is SAD plus d$\sub$max/, the value was just SAD. That resulted in increase of MU by 100${\times}$((1_d$\sub$max//SAD)$^2$-1)%. For 10${\times}$10 cm open field, 1 m SSD and at 10 cm depth in uniform medium of relative electron density (RED) 1, PDDs for 4 algorithms of dose calculation, Clarkson, convolution, superposition and fast-superposition, were compared with the measured. The calculated PDD were similar to the measured. For 10${\times}$10 cm open field, 1 m SSD and at 10 cm depth with 5 cm thick inhomogeneity of RED 0.2 under 2 cm thick RED 1 medium, PDDs for 4 algorithms were compared. PDDs ranged from 72.2% to 77.0% for 4 MV X-ray and from 90.9% to 95.6% for 6 MV X-ray. PDDs were of maximum for convolution and of minimum for superposition. For 15${\times}$15 cm symmetric wedged field, wedge factor was not constant for calculation mode, even though same geometry. The reason is that their wedge factor is considering beam hardness and ray path. Their definition requires their users to change the concept of wedge factor. RTP user should elaborately review beam data and calculation algorithm in commissioning.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.11A
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• pp.1056-1063
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• 2005

In this paper, we develop a dual beam automotive laser radar system which improve the defect of conventional unipolar one beam laser scheme. We introduce an SNR improving method using bipolar signal synthesizing scheme from two unipolar signals at the receiving unit via differential structure by allocating bipolar m-sequence into the two laser wavelengths, which have similar property like 2-D OOC, and investigate its performance. Simulation results show that the proposed dual beam scheme can have 3dB SNR improvement as compared with conventional unipolar signaling laser radar system. Also, we show the simple interference rejection scheme using differential structures. The proposed scheme have a merit to obtain additional 3dB SNR gain applied into the excellent results based on unipolar optical signal studied lately.

• Analytical Science and Technology
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• v.27 no.6
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• pp.292-299
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• 2014

Iopromide is an X-ray contrast agent that has been detected frequently with high concentration level in surface waters. Structural characterization of degradation products and measurement of degradation efficiency of iopromide by an electron beam irradiation were performed. For the fortified sample with iopromide, electron beam irradiation (UELV-10-10S, klysotrn, 10 MeV, 1 mA and 10 kW) was performed. The chemical structures of I_D_665 and I_D_663, which are degradation products of iopromide, were proposed by interpretation of mass spectra and chromatograms by LC/ESI-MS/MS. The mass fragmentation pathways of mass spectra in tandem mass spectrometry were also proposed. Iopromide was degraded 30.5~98.4% at dose of 0.3~5 kGy, and 97.8~30% in the concentration range $0.5{\sim}100{\mu}g/kg$ at electron beam dose of 0.3 kGy, respectively. Thus, increased degradation efficiency of iopromide by electron beam irradiation was observed with a higher dose of electron beam and lower concentration.

• Journal of the Optical Society of Korea
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• v.5 no.3
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• pp.99-109
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• 2001

This paper presents a phase-only modulation scheme for a three-dimensional (3-D) image matching system to improve optical efficiency of the system. The 3-D image matching system is based on the two mask heterodyne scanning. A hologram of the 3-D reference object is first created and then the phase of the hologram is extracted. The phase of the hologram is represented as one mask with the other mask being a plane wave. The superposition of each beam modulated by the two masks generated a scanning beam pattern. This beam pattern scans the 3-D target object to be recognized. The output of the scanning system gives out the correlation of the phase-only hologram of the reference object and the complex hologram of the target object. Since a hologram contains 3-D information of an object as a form of fringe pattern, the correlation of holograms matches whole 3-D aspect of the objects. Computer simulations are performed with additive gaussian noise and without noise for the complex hologram modulation scheme and the phase-only hologram modulation scheme. The computer simulation results show that the phase-only hologram modulation scheme improves the optical efficiency. Thus the system with the phase-only hologram modulation scheme is more robust than the system with the complex hologram modulation scheme.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.4
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• pp.413-420
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• 2003

In this paper, the correction method of antenna beam direction errors is introduced which caused by frequency scan effect in active Phased may antenna for satellite communications. The antenna makes the beam directional error from frequency scan effect when it has dual beam may structure with asymmetrical series connection, their frequencies are different and for from each other, their 3dB beamwidth is narrow, and scan range is wide. By proposed equations, estimated beam direction error angles can be calculated and active phase shifter control values also can be calculated to compensate them. In this paper, the active phased array antenna system was fabricated to measure beam direction errors both before and after correction, which has dual beam from 32${\times}$4 main level array and 4${\times}$2 second level array, frequency deviation 500 MHz max.(6.7 %) at 7.25 GHz∼7.75 GHz ranges, 0$^{\circ}$∼${\pm}$35$^{\circ}$nm ranges, and 35.6 dBi gain with 2.2$^{\circ}$3 dB beam width. Its beam direction error by frequency san effect which was 2.5$^{\circ}$max., was reduced to 0.2$^{\circ}$max. after correction. This was 7 dB improvement of signal loss. The active phased array antenna can accurately track the target satellite for communications by this proposed correction method.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.2
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• pp.267-274
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• 2002

Using a flexible rotating beam test bed, experimental verification of a flexible multibody dynamic simulations for a rotating beam model has been carried out. The test bed consists of a flexible arm, harmonic driver reducer, AC servo motor and DSP board with PC. The mechanical ports of the test bed has been designed using 3D CAD program. For the simulation model, mass and moment of inertia of each part of the flexible rotating beam test bed are also obtained from 3D CAD model. In the flexible multibody dynamic simulations, the substructuring model has been established to capture nonlinear effects of the flexible rotating beam. Through the experimental verification, substructuring model provides better results than those from the linear model in the high speed rotation.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1531-1534
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• 2005

Nano pattern is being utilized to produce micro optical components, sensors, and information storage devices. In this study, a study on nano pattern fabrication using raster-scan type Focused Ion Beam (FIB) milling is introduced. Because the intensity of ion beam has Gaussian distribution, the overlapping of the Gaussian beam results in a 3D pattern, and the shape of the pattern can be adjusted by variation of FIB milling parameters, such as overlap, ion dose, and dwell time. The Gaussian shape of single beam intensity has been investigated by experiment, and 3D nano patterns with pitch of 200nm generated by FIB is demonstrated.

• 한국정보디스플레이학회:학술대회논문집
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• 2002.08a
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• pp.395-398
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• 2002

The spherical aberration and optical integer (f) of the electron gun's main lens in color CRT is obtained, using electron beam trajectory. A spherical aberration is obtained from the relation between the object plane and the image of a beam trajectory. To analyze beam profile, 3rd and 1st order coefficient were obtained and used. It is shown that, in practice, they are applied to electron gun design.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.581-584
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• 2008

A generation of a particle beam is the key technique in a flow cytometry that measures the fluorescence and light scattering of individual cell and other particulate or molecular analytes in biomedical research. Recent methods performing this function require a laborious and time-consuming assembly. In the present work, we propose a novel device for the generation of an axisymmetrical focusing beam of microparticles (3-D focusing) in a single capillary without sheath flows. This work uses the concept that the particles migrate toward the centerline of the channel when they lag behind the parabolic velocity profile. Particle focusing of spherical particles was successfully made with a beam diameter of about 10 ${\mu}$m. Proposed device provides crucial solutions for simple and innovative 3-D particle focusing method for the applications to the MEMS-based micro-flow cytometry. We believe that this device can be utilized in a wide variety of applications, such as biomedical/ biochemical engineering.