• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.22-22
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• 2003

The purpose of this study was to compare the detection rate of brain metastasis according to size of nodule between 1.5T and 3.0T MRI 대상 및 방법： We reviewed 44 patients with primary tumors and clinical symptoms suggesting brain metastasis. After administration of double dose gadolinium-DTPA, MR imaging was performed with 3D SPGR sequence by 3.0T MRI and then with T1 SE sequence by 1.5T MRI. Consequently, comparison was done in 1.5T T1 SE sequence and 3.0T 3D SPGR sequence. With use of the signal intensity (SI) measurements in the metastatic nodules and adjacent tissue, metastatic nodule-to-adjacent tissue SI ratio were calculated. In each patient, the number of metastatic lesions detected in 1.5T and 3.0T, and their size were assessed qualitatively by three blinded readers.

• 대한기계학회논문집A
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• 제27권1호
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• pp.126-137
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• 2003

Many research works have been performed on the J-T approach for elastic-plastic crack-tip stress fields in a variety of plane strain specimens. To generalize the validity of J-T method, further investigations are however needed fur more practical 3D structures than the idealized plane strain specimens. The present study deals mainly with 3D finite element (FE) modeling of welded plate and straight pipe, and accompanying elastic, elastic-plastic FE analyses. Manual 3D modeling is almost prohibitive, since the models contain semi-elliptical interfacial cracks which require singular elements. To overcome this kind of barrier, we develop a program generating the meshes fur semi-elliptical interfacial cracks. We then compare the detailed 3D FE stress fields to those predicted with J-T two parameters. The validity of J-T approach is thereby extended to 3D yield-strength-mismatched weld joints, and useful information is inferred fur the design or assessment of pipe welds.

• 수산해양기술연구
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• 제31권1호
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• pp.45-53
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• 1995

Working depth of the model net was determined by using of the same experimental tank and the same model net that used in the forwarded report in a series studies. The depth of the net which indicates the depth of the head rope from the water surface, was determined by the photographs taken in front of the net mouth with the combination of towing velocity, warp length and distance between paired boats. The results obtained can be summarized as follows: 1. Working depth of model nets A and B was varied in the range of 0.09~1.66$m$,and 0.04~1.34$m$(which can be converted into 2.7~40.2$m$and 1.2~49.8$m$in the full-scale net) respectively, and the depth of model net A was slightly deeper than the depth of the model net B. 2. Working depth ($D$,which is appendixed m for the model net, f for the full-scale net, A and B for the types of the model nets) can be expressed as the function of towing velocity$V_t$, as in the model net($V_t$=$m$/$sec$) $D_{mA}$=(-1.99+0.65$L_w$) $e^{-1.72V_t}$ $D_{mA]$=(-1.91+1.04 $L_w$) $e^{2.88V_t}$ in the full-scale net($V_t$=$k$'$t$ $D_{fA}$=(-29.32+0.65$L_w$)$e^{0.40 V_t}$ $D_{fB}$=(-57.60+1.04$L_w$)$e^{-0.67 V_t}$ 3. Working depth 9$D$ appendixes are as same as the former) can be expressed as the function of warp length$L_w$) in the model net, and can be converted into full-scale net as in the model net ($V_t$=$m$/$sec$) $D_{mA}$=-0.99 $e^{-1.42V_t}$+0.67$e^{-1359V_t}$$L_w$ $D_{mB}$=-.258$e^{-3.77V_t}$+1.16$e^{-3.15V_t$ $L^w$, in the full-scale net($V_t$=k't) $D_{fA}$=-29.28$e^{-0.32V_t}$+0.67$e^{-0.37V_t$$L_w$ $D_{fB}$=-69.10$e^{-0.81V_t}$+1.16$e^{-0.72V_t}$$L_w$. 4. Working depth was gradually shallowed according to the increase of the distance between paired boats.

• Bulletin of the Korean Chemical Society
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• 제8권3호
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• pp.185-189
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• 1987

Reactions of $Ir(ClO)_4(CO)(PPh_3)_2$ with dicyano olefins, cis-NCCH = CH$CH_2$$CH_2$CN (cDC1B), trans-NCCH = CH$CH_2$$CH_2$CN (tDC1B), trans-NC$CH_2$CH = CH$CH_2$CN (tDC2B), and NC$CH_2$$CH_2$$CH_2$$CH_2$CN (DCB) produce binuclear dicationic iridium (I) complexes, $[(CO)(PPh_3)_2Ir-NC-A-CN-Ir(PPh_3)_2(CO)](ClO_4)_2$ (NC-A-CN = cDC1B (1a), tDC1B (1b), tDC2B (1c), DCB (1d)). Complexes 1a-1d react with hydrogen to give binuclear dicationic tetrahydrido iridium (Ⅲ ) complexes, $[(CO)(PPh_3)_2(H)_2Ir-NC-A-CN-Ir(H)_2(PPh_3)_2(CO)](ClO_4)_2$ (NC-A-CN = cDC1B (2a), tDC1B (2b), tDC2B (2c), DCB (2d)). Complexes 2a and 2b catalyze the hydrogenation of cDC1B and tDC1B, respectively to give DCB, while the complex 2c is catalytically active for the isomerization of tDC2B to give cDC1B and tDC1B and the hydrogenation of tDC2B to give DCB at $100^{\circ}C$.

• Journal of Animal Science and Technology
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• 제44권5호
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• pp.531-540
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• 2002

한우 수송아지에 대한 육성기 항병력 증진물질 투여 효과를 구명하기 위하여 75일령에 이유된 한우수송아지 30두를 대상으로 사료내 항병력 증진물질 첨가 종류에 따라 6개 처리(T1: 관행사육, T2: 황토 2%첨가, T3: Illite 2% 첨가, T4: Oligosacharides 0.04% 첨가, T5: Charcoal powder 2% 첨가, T6: Chromium picolinate 0.1% 첨가)를 두어 3개월령부터 7개월령까지 120일간 사양시험을 실시한 결과, 처리구별 일당 증체량은 T3, T6, T4, T5, T2 및 T1이 각각 0.92, 0.90, 0.90, 0.88, 0.83 및 0.82kg으로 Illite 및 크롬은 이유직후 송아지의 성장발육에 영향을 미쳤으나 가공되지 않은 황토급여는 성장발육에 뚜렷한 효과가 없었다. 육성기 120일간 1일 평균 농후사료 섭취량 및 체중대비 섭취비율은 각각 3.91${\sim}$4.15kg, 평균 4.03kg 및 3.1${\sim}$3.31%, 평균 3.21%였고, 1kg 증체에 소요된 TDN 량은 3.20${\sim}$3.57kg, 평균 3.35kg으로 T5, T3, T6, T4, T2 및 T1 순으로 우수하였다. 송아지의 혈청 내 IgG 농도는 처리구별로 10.2${\sim}$11.6mg/$m\ell$ 내에서 변화하여 정상 축에서 볼 수 있는 범위 내에 있었지만, T3 및 T5는 개시시에 비해 각각 6.9 및 2.8% 증가하였으며, 질병발생은 처리구별로 뚜렷한 차이가 없었다. 이상과 같은 결과들로 볼 때, 점토광물인 Illite는 다른 항병력 증진물질과 마찬가지로 어린 송아지의 발육 및 사료이용성을 증진시키지만 가공되지 않은 황토의 급여는 발육 및 사료이용성에 뚜렷한 차이가 없는 것으로 나타났다.

• Korean Journal of Radiology
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• 제22권8호
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• pp.1332-1340
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• 2021

Objective: To evaluate the feasibility of a new three-dimensional (3D) MR fingerprinting (MRF) technique for the prostate gland by conducting phantom and clinical studies. Materials and Methods: The new 3D MRF technique used in this study enables quick data acquisition and has a high resolution. For the phantom study, the MRF T1 and T2 values in an in-house phantom were compared with those of goldstandard mapping methods using linear regression analysis. For the clinical study, we evaluated 90 patients who underwent prostate imaging with MRF for suspected prostate cancer between September 2019 and February 2020. The mean T1 and T2 values were compared in the peripheral zone, transition zone, and focal lesions using paired t tests. The differences in the T1 and T2 values according to cancer aggressiveness were evaluated using one-way analysis of variance. Results: In the phantom study, the MRF T1 and T2 values showed a perfect correlation with the gold-standard T1 and T2 values (R > 0.99). In the clinical study, the T1 and T2 values in the peripheral zone were significantly higher than those in the transitional zone (p < 0.001, both). The T1 and T2 values in prostate cancer were significantly lower than those in the peripheral and transitional zones. The higher the grade of cancer, the lower the T2 values. Conclusion: The T1 and T2 values obtained from the 3D MRF showed a perfect correlation with the gold standard values in the phantom study. Differences in the T1 and T2 values among the different zones of the prostate gland were identified using 3D MRF in patients.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2000년도 International Symposium on Magnetics The 2000 Fall Conference
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• pp.584-584
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• 2000

Electronic structures of ordered Fe$_3X (X = Al, Si), and their derivative ternary alloys of Fe_2TX (T = 3d transition metal) have been investigated by using the linearized muffin-tin orbital (LMTO) band method. The role of the coupling between substituted transition metal and its neighbors is investigated by calculating the magnetic moments and local density of states (LDOS). It is shown that it is essential to include the coupling beyond nearest neighbors in obtaining the magnetic moment of Fe alloy. The preferential sites of T impurities in Fe_3X are determined from the total energy calculations. The derivative ternary alloys of Fe_2TX have characteristic electronic structures of semi-metal for Fe_2VAI and (nearly) half-metal for Fe_2TAI (T = Cr, Mn) and Fe_2TSi (T = V, Cr, Mn)

• Archives of Pharmacal Research
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• 제27권6호
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• pp.640-645
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• 2004

Histone deacetylase inhibitors are new class of chemotherapeutic drugs able to induce tumor cell apoptosis and／or cell cycle arrest. Trichostatin A, an antifungal antibiotic, and HC-toxin are potent and specific inhibitors of histone deacetylase activity. In this study, we have examined the antiproliferative activities of trichostatin A and HC-toxin in estrogen receptor positive human breast cancer, T47D cells. Both trichostatin A and HC-toxin showed potent antiprolifer-ative efficacy and cell cycle arrest at $G_2/M$ in T47D human breast cancer cells in a dose-dependent manner. Trichostatin A caused potent apoptosis of T47D human breast cancer cells and trichostatin A-induced apoptosis might be involved in an increase of caspase-3／7 activity. HC-toxin evoked apoptosis of T47D cells and HC-toxin induced apoptosis might not be medi-ated through direct increase in caspase-3/7 activity. We have identified potent activities of anti-proliferation, apoptosis, and cell cycle arrest of trichostatin A and HC-toxin in estrogen receptor positive human breast cancer cell line T47D.

• 한국버섯학회지
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• 제16권4호
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• pp.257-262
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• 2018

본 연구는 아미노산과 질소원이 증진된 수확후배지를 재사용하고, 느타리에서 영양원으로 사용되는 면실박의 사용을 줄이기 위해 수행되었다. 수확후배지의 질소원 증진을 위해 두 가지의 세균이 사용 되었으며, GM20-4는 느타리버섯의 수확후배지부터 분리되었고, Rhodobacter sphaeroides는 광주시농업기술 센터로부터 분양받았다. 처리구에 사용된 수확후배지는 건조 후 사용했으며, 위의 2가지의 미생물 처리에 의해 수확후배지의 총질소 함량은 0.34% 증가되었다. 8% D-SMS 가진 T1처리구와 18% D-SMS가 첨가된 T2가 대조와 T3처리구보다 발이율이 높았으며, 생물학적 효율은 대조 110%, T1이 114%, T2가 112%, T3가 79%로 조사되었다. 경제성, 수량 및 생물학적 효율을 고려해볼 때 18% 건조 수확후배지를 사용한 T2가 느타리 재배배지로 가장 효율적인 것으로 조사되었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.646-651
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• 2003

Quantitative performance test on the conventional 2D-PIV and the hybrid angular 3D-PIV (Stereoscopic PIV) was carried out. LES Data sets on an impinging jet which are provided on the webpage(http://www.vsj.or.jp/piv) for the PIV Standard Project were used for the generation of virtual images. The generated virtual images were used for the 2D-PIV and 3D-PIV measurements. The measurement results showed that the results obtained by 2D-PIV on average values are closer to the LES data than those obtained by 3D-PIV, but the turbulent properties obtained by 2D-PIV are largely underestimated than those obtained by 3D-PIV.