• Molecules and Cells
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• 제38권9호
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• pp.789-795
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• 2015

A chromosome territory is composed of chromosomal subdomains. The internal structure of chromosomal subdomains provides a structural framework for many genomic activities such as replication and DNA repair, and thus is key to determining the basis of their mechanisms. However, the internal structure and regulating proteins of a chromosomal subdomain remains elusive. Previously, we showed that the chromosome territory expanded after BAF53 knockdown. Because the integrity of chromosomal subdomains is a deciding factor of the volume of a chromosome territory, we examined here the effect of BAF53 knockdown on chromosomal subdomains. We found that BAF53 knockdown led to the disintegration of histone H2B-GFP-visualized chromosomal subdomains and BrdU-labeled replication foci. In addition, the size of DNA loops measured by the maximum fluorescent halo technique increased and became irregular after BAF53 knockdown, indicating DNA loops were released from the residual nuclear structure. These data can be accounted for by the model that BAF53 is prerequisite for maintaining the structural integrity of chromosomal subdomains.

• 천문학회보
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• 제38권2호
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• pp.64.1-64.1
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• 2013

High energy photons and mechanical energy produced by the process of star formation result in copious FIR molecular and atomic lines, which are important coolants of the system. Photons thermally or mechanically induced could dissociate water in the dense envelope to change relative abundances among the species O, OH, and H2O. Here we analyze OH emission lines toward embedded young stellar objects (YSOs) observed as part of the Herschel open time key program, 'Dust, Ice, and Gas In Time (DIGIT)' in order to study the physical conditions of associated gas and the energy budget loaded on the OH line emission. According to our analysis of the Herschel/PACS spectra, OH emission peaks at the central spaxel in most of sources, but several sources show spatially extended emission structures. In the extended emission sources, the distribution of OH emission is correlated with that of [OI] emission and extended along the outflow directions. Considering the diversity of source properties, ratios between detected OH lines are relatively constant among sources. In addition, each OH line has strong correlation with bolometric luminosity. For detail analyses with rotation diagram and non-LTE LVG model, we present the results from GSS30-IRS1 and Elias29.

• 대한조선학회논문집
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• 제39권1호
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• pp.38-48
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• 2002

파랑집중 이론에 기초하여 모형시험수조에서 다방향 극한파를 생성하는 연구를 수행하였다. 파랑의 집중도에 대한 파향 범위, 주파수 폭, 중심 주파수 등의 영향을 고찰하였다. 등파고와 등기 울기 스펙트럼 모델에 의한 결과를 서로 비교하였으며, Boussinesq 방정식과 유한요소법에 기초한 수치해와 이론해를 또한 서로 비교하였다. 효율적인 파랑집중을 위해서는 파향과 주파수 모두를 효과적으로 제어하는 것이 필수적이다. 파랑집중도는 중심주파수 보다는 주파수 폭에 좌우되며, 동일한 조건하에서 두 스펙트럼 모델은 동등한 정도의 파랑집중 효율을 나타낸다.

• 대한조선학회논문집
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• 제38권1호
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• pp.27-36
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• 2001

현재, 유럽에서 중요한 역할을 담당하고 있는 수송모델로서 바다와 강을 연계한 Sea-river 수송모델은 황해권 지역에서의 국내 외 화물수송과 여객수송에 있어 장래에 매우 중요한 역할을 할 것이다. 본 연구에서는 육상수송에 따른 국내 교통 혼잡문제와 극동아시아 국가의 화물량 증대로 인한 물류 문제의 개선을 위해 경인운하의 운항조건에 적합한 sea-river 연계 바아지선단의 수송모델을 제안한다. 즉, 본 연구에서는 경인운하의 형상과 크기 등의 제한조건 등을 고려하여 바아지선단의 수송효율 측면의 경제성을 바탕으로 경인운하를 이용한 황해권의 sea-river 연계 수송모델로서 효율적인 바아지선단 구성의 표준화를 제시하고자 한다.

• 한국환경교육학회지:환경교육
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• 제16권2호
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• pp.29-38
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• 2003

The main purpose of this study is to search a new perspective of environmental education through investigating of alternative education. Environmental education is introduced by needs of society for an effective way of solving environmental problems. But it also has a meaningfulness which is internal need of education for proposing and fostering ecological human corresponds with crisis of modernism. In spite of excessive rhetoric, vision of formal environmental education is very negative. Formal environmental education is restricted to optional course. So, its potential isn't fulfil. Education is both part of the problem and the solution. Education is proclaimed at high level as the key to a more sustainable society and yet it daily plays a part in reproducing an unsustainable society. If environmental education is to fulfil its potential as an agent of environmental problem solution, it becomes both part of the ideal and the practice of education. In this point, alternative education is a model of what environmental education ought to be. Environmental education and alternative education have a common ground in end of education and critical position to the modern education system.

• 복식문화연구
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• 제21권4호
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• pp.585-595
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• 2013

The most researches developing pattern of compression style sportswear were targeted at the live model that has muscular body build. The purpose of this study was developing a method for classifying men's lower body types in terms of muscular body build. The 3D human body scan data and body measurements of 30s of Size Korea were analyzed. The subjects (n=203) were men between the ages of 30 and 39 years. Men's muscular body build was classified with two key dimensions, thigh girth and calf girth. The subjects were divided into four groups. From each group, average subjects (n=42) whose height and weight were close to the mean value ($mean{\pm}1/2$ S.D.) were selected. 42 subjects were divided up as four groups. Group I (n=7) was thigh and calf developed body type. Group II (n=9) was thigh developed body type. Group III (n=11) was calf developed body type. Group IV (n=15) was thigh and calf undeveloped body type. Four groups had distinct different at widths (n=4), depths (n=4), and girths (n=9) dimensions. The results showed that the muscular men in their 30s could be defined by thigh and calf girths. The thigh developed muscular men had thigh girth over 60cm and the calf developed muscular men had calf girth over 38cm. From each group one representative was selected by 3D body scan figure.

• 패션비즈니스
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• 제22권6호
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• pp.25-38
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• 2018

Recently, issues on the environment, which have become key bottlenecks relative to sustainable economic development, have generated common concern. However, relatively scant research has been devoted to consideration of relations between consumers' environmental concern, green fashion advertisement value, and green consumption. In this study, using structural equation modeling (SEM), effects of environmental concern, perceived green fashion advertisement value, and attitude towards green fashion advertisements, on ecological purchases and their interrelationships are investigated. A model is constructed to link aforementioned constructs. Data, was collected through a questionnaire-based online survey (www.sojump.com) of 260 Korean consumers and 260 Chinese consumers. Findings suggest that environmental concern can improve their perception of green advertisement value. One of the findings showed strong positive relationship among green advertisement value, positive attitude, and purchase intention towards green fashion advertisement, while environmental concern negatively influenced their attitude towards green fashion advertisements. It suggests that if companies adopt green advertising strategies, environmentally-conscious consumers are willing to pay more, to purchase green fashion goods in to satisfy their needs. We should put more effort in educating consumers about environmental issues, to raise the level of environmental awareness and satisfy their concerns relative to green fashion goods. Conversely, there is significant positive relationship with the moderating effect of consumers' nationality in all paths, so results above would make significant contributions to green literature, and would also contribute to advertisement strategy implications as well. Especially fashion marketers, an use accurate and fair environmental claims in their advertisements to increase sale and profits.

• 생약학회지
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• 제51권4호
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• pp.317-324
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• 2020

Mast cells play a key role in IgE-mediated allergic response. We investigated whether Swertia pseudochinensis Hara extract (SPE) inhibits IgE-mediated allergic response in mast cells and an allergic animal model. Additionally, we explored SPE's mechanism of action in mast cells. Our results showed that SPE inhibited both antigen-stimulated degranulation and the production of TNF-α and IL-4 in bone marrow-derived mast cells (BMMCs) and rat basophilic leukemia (RBL)-2H3 cells. SPE also suppressed allergic response in IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. As for the mechanism of action of SPE in mast cells, it inhibited the activation of Syk kinase, a critical signaling protein in the FcεRI-mediated signaling pathway, and also the activation of LAT, a downstream adaptor protein of Syk. We further observed the reduced activation of mitogen-activated protein (MAP) kinases (P38, ERK1/2, and JNK) and Akt in mast cells. Our results described for the first time that SPE has an anti-allergic effect by suppressing mast cells through the inhibition of Syk kinase. Therefore, SPE may be useful for the treatment of type I allergic diseases.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.1564-1569
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• 2009

Project managers play a key role in cost, time, and quality of a project. Selection of an appropriate project manager, therefore, is considered as one of the most important decisions in any construction project. It should be noted that most important decision makings are carried out by the project manager throughout the project. Traditionally, project manager selection in construction companies in Iran is through organizing an interview with candidates and selecting the most appropriate choice in accordance with the capabilities, potentials and individual specifications coupled with the requirements of the project. In the same direction, organizing interview on selection of appropriate candidate is usually carried out by senior managers of companies. Determination of the most important criteria for selection of project managers and also identification of significance coefficient of each criterion can highly help senior managers of companies to make sound selection decisions. In this paper, a numerical model has been considered for determination of significance of each criterion, details of which are submitted for selection of project manager in Iranian petrochemical, oil and gas sector companies. For this reason, all criteria- considered by senior managers of the companies under study- are first determined. Then, information obtained through 38 interviews, conducted by senior managers of the mentioned companies while selecting project manager, is analyzed. Significant coefficient of each criterion is calculated through the accumulated data using fuzzy curves method.

• 한국항공우주학회지
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• 제38권12호
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• pp.1217-1222
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• 2010

본 논문은 근접감시 무인항공기(KUS-9)의 비행제어 소프트웨어(S/W) 개발 과정과 모델기반 개발 기술 적용 결과를 다룬다. 대표적인 상용 모델기반 설계도구인 MATLAB $Simulink^{(R)}$를 활용하여 통합개발 환경을 구축하고 비행제어법칙, 운용로직, 비행 시뮬레이션 모델, HILS(Hardware-in-the-Loop Simulation) 시스템 모델을 설계하였다. 설계 과정에서 요구사항 충족을 위한 시뮬레이션 및 동료검토를 수행하고 DO-178B 검증 도구를 이용하여 모델을 검증한 후 S/W시험 도구를 통해 C코드의 무결성을 검증하였다. 탑재 소프트웨어는 두 기종의 하드웨어 및 실시간운용체제(${\mu}C$/OS-II, VxWorks)에 탑재하여 HILS시험과 비행시험을 수행하였다. 모델기반 개발 기법을 적용함으로써 S/W 재사용성과 확장성을 확보하고 자동코드생성 기술을 이용하여 고신뢰 비행제어 S/W를 단기간에 성공적으로 개발하였다.