• Title/Summary/Keyword: 309L

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Factors Associated with Health-Related Quality of Life in Tuberculosis Patients Referred to the National Research Institute of Tuberculosis and Lung Disease in Tehran

  • Kakhki, Ali Darvishpoor;Masjedi, Mohammad Reza
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.4
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    • pp.309-314
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    • 2015
  • Background: In tuberculosis (TB) patients, health-related quality of life (HRQoL) is significant in self-management, which in turn can be effective in therapeutic acceptance and prevention of treatment failure due to multi-drug resistant TB. This study was conducted to evaluate HRQoL and associated factors in TB patients referred to the National Research Institute of Tuberculosis and Lung Disease (NRITLD). Methods: In this study, patients were selected from TB clinics of the NRITLD in Tehran. In addition to an Iranian version of the Short-Form Health Survey (SF-36), demographic and disease characteristic questionnaires were used for data collection. The data were then analyzed using SPSS software. Results: Two hundred five TB patients, with the average age of $42.33{\pm}17.64$ years, participated in this study. The HRQoL scores in different domains ranged from $14.68{\pm}11.60$ for role limitations due to emotional problems to $46.99{\pm}13.25$ for general health perceptions. The variables of sex, marital status, education, job status, place of residence, and cigarette smoking, influenced the HRQoL scores in different dimensions. Conclusion: According to the study findings are the important variables that influenced the HRQoL of TB patients. The consideration of its can improve the HRQoL of TB patients.

신규항암제 DA-125의 액상 안정화

  • 박양환;박광신;권종원;차봉진;정비환;정기화
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.309-309
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    • 1994
  • DA-125에 당류로서 Inositol, Dextrose, Iactose, Mannitol 및 Sorbitol을 첨가하여 DA-125 단독으로 용해한 시료와 비교 평가하였을 때 DA-125의 안정성에 큰 영향이 없었으며, 아미노산 중 L-lysine첨가시 안정성이 향상되는 컷으로 나타났다. 염류를 사용하였을 때는 NaCl, MgSO$_4$첨가시 안정성이 크게 증가하였으며, NaCl의 첨가 농도에 따른 안정성을 시험한 결과 NaCl의 농도 증가에 따라 DA-125의 안정성이 증가하는 것으로 나타났다. 또한 기타 안정화제로 Sodium Bisulfite 첨가시 안정성이 증가되었다. 안정성 시험 중 pH및 용액상태는 변화하지 않았다.

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Expression and Characterization of Escherichia coli Adhesin Protein Linked to Cholera Toxin A2/B Subunits in Escherichia coli

  • Lee, Young-Hwa;Ryu, Dong-Kyun;Rhee, Dong-Kwon;Pyo, Suhk-Neung
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.309.2-309.2
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    • 2002
  • The FimH subunit of type l-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically coupled to the ctxa2b gene, which was then cloned into pMAL -p2E expression vector. The chimaeric construction of pMALfimH/ctxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)

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Sap Collection and Major Components of Acer okamotoanum Nakai Native in Ullungdo (울릉도 자생 우산고로쇠나무의 수액채취와 주요성분)

  • Moon, Hyun-Shik;Kwon, Su-Duk
    • Korean Journal of Medicinal Crop Science
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    • v.12 no.3
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    • pp.249-254
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    • 2004
  • The collecting amount by DBH class and contents of mineral and free sugar in the sap of Acer okamotoanum Nakai being autogenous in Ullungdo were investigated. The total amount of sap was 376 l Sap of A. okamotoanum were increased with increasing DBH, 67 l (18%), 121 l (32%) and 188 l (50%) from small (below 18 cm), middle $(20{\sim}28\;cm)$ and large (above 30cm) diameter tree, respectively. Amounts of sap was required by big temperature fluctuation in day and night. The contents of solid, ash and sugar were 3.04%, 0.06% and 3.06% in the sap of A. okamotoanum. Free sugar determined in the sap was sucrose with 30.6 g/l, but glucose, fructose and maltose were not detected. The sap of A. okamotoanum was composed of seven kinds of mineral. The prominent minerals in the sap were Ca and K, and the concentrations of Ca and K were 522 mg/l and 309 mg/l, respectively.

IRRADIATION EMBRITTLEMENT OF CLADDING AND HAZ OF RPV STEEL

  • Lee J.S.;Kim I.S.;Jang C.H.;Kimura A.
    • Nuclear Engineering and Technology
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    • v.38 no.5
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    • pp.405-410
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    • 2006
  • Microstructural features and their related mechanical property changes in the 309L cladding and the heat affected zone (HAZ) of SA508 cl.3 steel were investigated through the use of TEM, tensile and small punch (SP) tests. The specimens were irradiated at 563 K up to the neutron fluences of $5.79{\times}10^{19}n/cm^2$ (>1MeV). The microstructure of the clad was mainly composed of a fcc ${\gamma}-phase$, a low percentage of bcc ${\delta}-ferrite$, and a brittle ${\sigma}-phase$. Along the weld fusion line there formed a heavy carbide precipitation with a width of $20{\sim}40{\mu}m$, showing preferential cracking during plastic deformation. The yield stress and ductile-to-brittle transition temperature (DBTT) of the irradiated clads increased. The origin of the hardening and the shift of the DBTT are discussed in terms of the irradiation-produced defect clusters of a fine size and brittle ${\sigma}-phase$.

Bilateral Thoracic Ganglion Cyst : A Rare Case Report

  • Kazanci, Burak;Tehli, Ozkan;Turkoglu, Erhan;Guclu, Bulent
    • Journal of Korean Neurosurgical Society
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    • v.53 no.5
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    • pp.309-311
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    • 2013
  • Ganglion cysts usually arise from the tissues around the facet joints. It is usually associated with degenerative cahanges in facet joints. Bilateral thoracic ganglion cysts are very rare and there is no previous case that located in bilateral intervertebral foramen compressing the L1 nerve root associated with severe radiculopathy. We report a 53 years old woman who presented with bilateral groin pain and severe numbness. Magnetic resonance imaging revealed bilateral cystic mass in the intervertebral foramen between 12th thoracal and 1st lumbar vertebrae. The cystic lesions were removed after bilateral exposure of Th12-L1 foramens. The result of hystopathology confirmed the diagnosis as ganglion cyst. The ganglion cyst may compromise lumbar dorsal ganglion when it located in the intervertebral foramen. The surgeon should keep this rare entity in their mind for differential diagnosis.

Evaluation of Mechanical Properties of RPV Clad by Small Punch Tests

  • Lee, Joo-Suk;Kim, In-Sup
    • Nuclear Engineering and Technology
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    • v.34 no.6
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    • pp.574-585
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    • 2002
  • The microstructural characteristics and its related mechanical properties of RPV cladding have been investigated using small punch (SP) tests. SA508 Cl.3 RPV steel plates were overlay cladded with the type ER309L welding consumables by submerged arc welding process. Although the RPV clad material had a small portion of 5 ferrite phase, it still showed the ductile to brittle transition behavior The transition temperature was determined by the SP test and it depended on the content of $\sigma$ phase, specimen size, and determination methods. The fracture appearance of SP specimen was changed from circumferential to radial cracking as test temperature became low, and below the transition temperature region, ER309L cladding usually fractured along the 6 ferrite by the low temperature failure of ferrite phase.

Solvolysis of (1S)-(+)-Menthyl Chloroformate in Various Mixed Solvents

  • Koh, Han Joong;Kang, Suk Jin
    • Journal of the Korean Chemical Society
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    • v.65 no.5
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    • pp.309-312
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    • 2021
  • The solvolysis of (1s)-(+)-menthyl chloroformate (1) were studied kinetically in 28 pure and various mixed solvents. The analysis using the extended Grunwald-Winstein equation in the solvolysis of 1 obtained the l value of 2.46 ± 0.18, the m value of 0.91 ± 0.07, and the correlation coefficient of 0.950. The solvolysis of 1 might proceed via an associative SN2 mechanism enhancing bond making than bond breaking in the transition state (TS). The value of l/m is 2.7 within the ranges of value found in associative SN2 reaction. This interpretation is further supported by a relatively large solvent kinetic isotope effect (SKIE, 2.16).