• Title/Summary/Keyword: 3-parameter model

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Relationship between In-situ Hydraulic Conductivity and Van Genuchten Parameters of Unsaturated Fractured Hornfels (불포화 균열 혼펠스의 현장 수리전도도와 반 게누텐 매개변수의 상관성)

  • Cheong, Jae-Yeol;Cho, HyunJin;Kim, Soo-Gin;Ok, Soonil;Kim, Kue-Young;Hamm, Se-Yeong
    • The Journal of Engineering Geology
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    • v.30 no.2
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    • pp.147-160
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    • 2020
  • Unsaturated hydraulic conductivity of near-surface unconsolidated layers depends on the physical properties and water content of the unconsolidated layers. So far, many studies have been conducted on the unsaturated hydraulic conductivity of near-surface unconsolidated layers. However, researches on hydraulic conductivity of unsaturated fractured rocks have been relatively rare. In relation to the construction of a low/intermediate level radioactive waste surface-disposal facility, this study compared and analyzed van Genuchten parameters (α, n) in the laboratory and the hydraulic conductivity obtained in field tests for fractured hornfels at a radioactive-waste disposal site of Korea. The relationship between the field hydraulic conductivity and van Genuchten parameters using data from the ten depth intervals of three boreholes resulted in that the correlation coefficient (R) between the hydraulic conductivity and the van Genuchten parameter α was 0.7607, showing positive correlation whereas the R between the hydraulic conductivity and the van Genuchten shape-defining parameter n was -0.8720, showing negative correlation. Hence, this study confirmed the relationship between the field hydraulic conductivity and the van Genuchten unsaturated functions for the unsaturated fractured hornfels.

Pharmacokinetics of amoxicillin trihydrate in cultured eel Anguilla japonica by single oral and intravenous administrations (Amoxicillin trihydrate의 단독 경구투여 및 정맥투여에 따른 뱀장어, Anguilla japonica 체내 약물동태학적 특성)

  • Jeon, Eun-Ji;Seo, Jeong-Soo;Kim, Jin-Do;Jung, Sung-Hee;Kim, Myoung-Sug;Hwang, Jee-Youn;Park, Myoung-Ae;Jee, Bo-Young;Kim, Jin-Woo;Kim, Yi-Cheong
    • Journal of fish pathology
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    • v.23 no.3
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    • pp.357-367
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    • 2010
  • The pharmacokinetic properties of amoxicillin trihydrate (Amox) were studied after single oral administration and single intravenous injection to cultured eel, Anguilla japonica, respectively (average $220{\pm}10\;g$, $28{\pm}1^{\circ}C$). Plasma samples were taken at 3, 5, 10, 15, 24, 30, 48, 96 and 144 h post-dose. The kinetic profile of absorption, distribution and elimination of Amox in plasma were analyzed fitting to a two-compartment model by WinNonlin program. In oral dosage of 40 and 80 mg/kg body weight, the peak plasma concentrations of Amox, which attained at 3~12 h post-dose, were 3.4 and $3.3\;{\mu}g/ml$, respectively. In intravenous injection with 1 mg/kg, the peak plasma concentrations of Amox, which attained at 9 h post-dose, was $7.2\;{\mu}g/ml$. The following parmeters were calculated for a single oral dosage of 40 and 80 mg/kg body weight, respectively: AUC (the area under the concentration-time curve)= 464 and $667\;{\mu}g{\cdot}h/ml$; $T_{max}$ (time for maximum concentration)= 2.1 and 3.6 h; $C_{max}$ (maximum concentration)= 3.04 and $3.4\;{\mu}g/ml$. Following intravenous injection at 1 mg/kg, this parameters were AUC= $748\;{\mu}g{\cdot}h/ml$; $C_{max}=4.2\;{\mu}g/ml$. The apparent oral bioavailability at 40 and 80 mg/kg were 1.6 and 1.1%, respectively. Despite using the trihydrate form of amoxicillin, the oral bioavailability was low in eel.

Probabilities of Pulmonary and Cardiac Complications and Radiographic Parameters in Breast Cancer Radiotherapy (유방암의 방사선치료에서 방사선학적 지표에 따른 폐 및 심장의 부작용 확률)

  • Noh, O-Kyu;Park, Sung-Ho;Ahn, Seung-Do;Choi, Eun-Kyung;Lee, Sang-Wook;Song, Si-Yeol;Yoon, Sang-Min;Kim, Jong-Hoon
    • Radiation Oncology Journal
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    • v.28 no.1
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    • pp.23-31
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    • 2010
  • Purpose: To evaluate the relationship between the normal tissue complication probability (NTCP) of 3-dimensional (3-D) radiotherapy and the radiographic parameters of 2-dimensional (2-D) radiotherapy such as central lung distance (CLD) and maximal heart distance (MHD). Materials and Methods: We analyzed 110 patients who were treated with postoperative radiotherapy for breast cancer. A two-field tangential technique, a three-field technique, and the reverse hockey stick method were used. The radiation dose administered to whole breast or the chest wall was 50.4 Gy, whereas a 45 Gy was administered to the supraclavicular field. The NTCPs of the heart and lung were calculated by the modified Lyman model and the relative seriality model. Results: For all patients, the NTCPs of radiation-induced pneumonitis and cardiac mortality were 0.5% and 0.7%, respectively. The NTCP of radiation-induced pneumonitis was higher in patients treated with the reverse hockey stick method than in those treated by other two techniques (0.0%, 0.0%, 3.1%, p<0.001). The NTCP of radiation-induced pneumonitis increased with CLD. The NTCP of cardiac mortality increased with MHD ($R^2=0.808$). Conclusion: We found a close correlation between the NTCP of 3-D radiotherapy and 2-D radiographic parameters. Our results are useful to reanalyze the previous 2-D based clinical reports about breast radiation therapy complications as a viewpoint of NTCP.

Dependence of Electronic Spectra on the Degree of Conjugation in Organocobalt(Ⅲ) Complexes (공액도에 따른 유기코발트 착화합물의 전자스펙트럼에 관한 연구)

  • Hye Kyung Seo;Chan Ah Bong;Young Ae Hwang Park
    • Journal of the Korean Chemical Society
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    • v.37 no.12
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    • pp.1047-1052
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    • 1993
  • The electronic spectra of enzyme-model organocobalt(Ⅲ) complexes containing completely or partially conjugated macrocyclic ligands were measured in various solvents to investigate the solvent effect on the charge transfer band for the axial cobalt-carbon bond by the extent of conjugation in the equatorial macrocyclic ring; completely conjugated, $CH_3CoL,\;C_6H_5CoL,\;CNCoL,\;CH_3CoL',\;CNCoL'$, partially conjugated $CH_3(py)Co(DH)_2, CH_3CoL"$, unconjugated dienes, $[CH_3Co(1,4-CT)](ClO_4)_2$, and open ring, $CH_3Co(salen)$. The position of the charge transfer band which corresponds to the cobalt-carbon bond was shifted to a shorter wavelength as the polarity of solvent increased and the transition energy $(E_T)$ had a linear relationship with solvent polarity parameter, Z-value, only in the case of completely conjugated system. However, the linear correlation between $E_T$and Z was not observed for partially conjugated and open ring systems.

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Model Equations to Estimate the Soil Water Characteristics Curve Using Scaling Factor (Scaling Factor를 이용한 토양수분특성곡선 추정모형)

  • Eom, Ki-Cheol;Song, Kwan-Cheol;Ryu, Kwan-Shig;Sonn, Yeon-Kyu;Lee, Sang-Eun
    • Korean Journal of Soil Science and Fertilizer
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    • v.28 no.3
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    • pp.227-232
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    • 1995
  • The model equations including scaling factors to estimate the soil water characteristics curve(SWCC) without direct measurement of soil water tension were developed. Scaling were applied to a data set of soil water content, soil water tension, particle size distribution, and OM contents of the 134 soil samples with the 10 soil textural classes. The capability of the model equations was tested on another 205 soil samples. The parameter, ${\theta}^*$, of soil water contents was used by scale transformation as follows : ${\theta}^*=[{\theta}i-{\theta}(1.5MPa)]$/$[{\theta}(10KPa)-{\theta}(1.5MPa)]$ Using ${\theta}^*$ a model equation to estimate SWCC, which was applicable to all textural classes, was developed as follows: $H(0.1MPa)=0.13{\cdot}({\theta}^*)^{-2.04}$. Other model equations to estimate the water content at the soil water tension of 10KPa [${\theta}(10KPa)$] and 1.5MPa [${\theta}(1.5MPa)$], which are required to ${\theta}^*$ were developed by using scale factors of sand(S) and silt(Si) content and organic matter content(OM) as foilows : ${\theta}(10KPa)=26.80-3.99ln[S]+2.36{\sqrt{[Si]}}+2.88[OM]$ ($R=0.81^{**}$) ${\theta}(1.5KPa)=15.75-2.86ln[S]+0.55{\sqrt{[Si]}}+0.70[OM]$ ($R=0.76^{**}$) The measured and estimated values of ${\theta}(1/30MPa)$ on the 205 soil samples were highly correlated on 1 : 1 corresponding line with $R=0.85^{**}$.

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Precipitation Characteristics in Mountainous Regions During Changma Period in 2023 (2023년 장마기간 동안 산악지역의 강우 특성)

  • Inhye Kim;Keunchang Jang;Byung Oh Yoo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.26 no.3
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    • pp.161-173
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    • 2024
  • In South Korea, 50-65% of the annual precipitation is concentrated during the summer monsoon season, which is called Changma. In 2023, extreme precipitation was observed during Changma period, and was recorded the highest amount in southern part of Korea. Extreme precipitation in forest region is one of significant factors related to the landslide. Therefore, accurate monitoring and understanding of precipitation patterns are crucial for preventing the landslide disasters in Changma period. This study investigated the precipitation patterns including precipitation intensity, duration, and total amount in mountainous and non-mountainous regions during the Changma period using dataset observed from the Korea Forest Service's Automatic Mountain Meteorology Observation Station (AMOS) and the Korea Meteorological Administration (KMA). Precipitation map produced from the Modified Korean-Parameter elevation Regressions an Independent Slopes Model (MK-PRISM) was also used to verify precipitation patterns in areas affected by landslides in Gyeongsangbuk-do province. The results used from precipitation observations revealed that the total amount of precipitation was greater at elevations such as mountainous regions. In particular, extreme precipitation events such as precipitation duration exceeding 50 hours with amount of over 300 mm and heavy rainfalls of over 30 mm/hr occurred at landslide areas including Mungyeong, Bonghwa, and Yeongju in Gyeongsangbuk-do province. Total amount of precipitation produced by MK-PRISM in these areas during Changma period were more than double compared with 30 years mean values obtained from KMA. The results conducted in this study indicate that it is essential to establish the thresolds considering recent precipitation patterns to effectively prepare and prevent for landslide disasters.

Hydrogeological characteristics of the LILW disposal site (처분부지의 수리지질 특성)

  • Kim, Kyung-Su;Kim, Chun-Soo;Bae, Dae-Seok;Ji, Sung-Hoon;Yoon, Si-Tae
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.4
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    • pp.245-255
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    • 2008
  • Korea Hydro and Nuclear Power Company(KHNP) conducted site investigations for a low and intermediate-level nuclear waste repository in the Gyeong Ju site. The site characterization work constitutes a description of the site, its regional setting and the current state of the geosphere and biosphere. The main objectives of hydogeological investigation aimed to understand the hydrogeological setting and conditions of the site, and to provide the input parameters for safety evaluation. The hydogeological characterization of the site was performed from the results of surface based investigations, i.e geological mapping and analysis, drilling works and hydraulic testing, and geophysical survey and interpretation. The hydro-structural model based on the hydrogeological characterization consists of one-Hydraulic Soil Domain, three-Hydraulic Rock Domains and five-Hydraulic Conductor Domains. The hydrogeological framework and the hydraulic values provided for each hydraulic unit over a relevant scale were used as the baseline for the conceptualization and interpretation of flow modeling. The current hydrogeological characteristics based on the surface based investigation include some uncertainties resulted from the basic assumption of investigation methods and field data. Therefore, the reassessment of hydrostructure model and hydraulic properties based on the field data obtained during the construction is necessitated for a final hydrogeological characterization.

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Reaction Rate Analysis of Combustion for Indonesian Coal Char Applied by External/Internal Diffusion (외부 및 내부 확산을 적용한 인도네시아 석탄촤의 연소 반응율 분석)

  • Hwang, Chan-Won;Kim, Ryang-Gyoon;Ryu, Kwang-Il;Wu, Ze-Lin;Jeon, Chung-Hwan
    • Korean Chemical Engineering Research
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    • v.52 no.1
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    • pp.133-140
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    • 2014
  • The experiment was designed to compare the char combustion kinetics of pulverized Indonesia coals commonly utilized in Korea power plants. The reaction rate of coal char has been formulated using the external and internal effectiveness factors to describe the diffusion effect quantitatively. The Random Pore Model (RPM) was used for applying internal specific surface area as a function of carbon conversion ratio. Reaction rate was obtained from reaction time using the Wire Heating Reactor (WHR) which can heat and measure the char particle temperature at the same time. BET and TGA were used to obtain physical properties such as internal specific surface area and structural parameter. Three kinds of Indonesia Sub-bituminous coals "BARAMULTI, ENERGYMAN, AGM" were used in order to derive the activation energy and pre-exponential factor. The results of this study showed that the effect of internal diffusion than that of external diffusion is the dominant as comparison of kinetics was reflected in external and internal effectiveness factors. For three kinds of coal char, finally, activation energy of intrinsic kinetics indicates 110~118 kJ/mol.

EM Algorithm with Initialization Based on Incremental ${\cal}k-means$ for GMM and Its Application to Speaker Identification (GMM을 위한 점진적 ${\cal}k-means$ 알고리즘에 의해 초기값을 갖는 EM알고리즘과 화자식별에의 적용)

  • Seo Changwoo;Hahn Hernsoo;Lee Kiyong;Lee Younjeong
    • The Journal of the Acoustical Society of Korea
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    • v.24 no.3
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    • pp.141-149
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    • 2005
  • Tn general. Gaussian mixture model (GMM) is used to estimate the speaker model from the speech for speaker identification. The parameter estimates of the GMM are obtained by using the Expectation-Maximization (EM) algorithm for the maximum likelihood (ML) estimation. However the EM algorithm has such drawbacks that it depends heavily on the initialization and it needs the number of mixtures to be known. In this paper, to solve the above problems of the EM algorithm. we propose an EM algorithm with the initialization based on incremental ${\cal}k-means$ for GMM. The proposed method dynamically increases the number of mixtures one by one until finding the optimum number of mixtures. Whenever adding one mixture, we calculate the mutual relationship between it and one of other mixtures respectively. Finally. based on these mutual relationships. we can estimate the optimal number of mixtures which are statistically independent. The effectiveness of the proposed method is shown by the experiment for artificial data. Also. we performed the speaker identification by applying the proposed method comparing with other approaches.

A Stochastic Numerical Analysis of Groundwater Fluctuations in Hillside Slopes for Assessing Risk of Landslides (산사태 위험도 추정을 위한 지하수위 변동의 추계론적 수치 해석)

  • 이인모
    • Geotechnical Engineering
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    • v.3 no.4
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    • pp.41-54
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    • 1987
  • A stochastic numerical analysis for predicting the groundswater fluctuations in hillside slopes is performed in this paper to account for the uncertainties associated with the rainfall and site characteristics. The effect of spatial variabilities of aquifer parameters and the effect of temporal variability of recharge on the groundwater fluctuations are studied in depth. The Kriging is used to account for the spatial tariabilities of aquifer parameters. This technique prolevides the best linear unbiased estimator of a parameter and its minimum variance from a litsitem number of measured data. A stochastic one-dimensional numerical model is delreloped b) combining the groundwater flow model, the Kriging, and the first-order second-moment analysis. In addition, a two dimensional detelministic groundwater model is developed to study the change of ground water surfas in the transverse direction as well as in the downslope direction. It is revealed that the undulations of the impervious bedrock in addition to the permeability and the specific yield have an important influence on the fluctuations of the groundwater surface. It is also found that th'e groundwater changes significantly in the transverse direction as well as in the downslope direction. The results obtained in this analysis may be used for evaluation of landslide risks due to high porewater pressure.

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