• Title/Summary/Keyword: 3-D Mechanism

Search Result 1,731, Processing Time 0.025 seconds

Salinity Effects on the Hydraulic Conductivity of Uplands (밭토양(土壌)의 수리전도도(水理伝導度)에 대(対)한 염류효과(塩類効果))

  • Park, Chang-Seo;O'Connor, George A.
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.16 no.1
    • /
    • pp.7-13
    • /
    • 1983
  • Laboratory determinations of saturated hydraulic conductivity were conducted with four soils varying in texture from sand to clay and with five waters with different salinity level. The waters varied in total dissolved solids from 1,250 to $15,000mg/{\ell}$ and in SAR from 16 to 57 and were representative of saline waters in New Mexico. Saturated hydraulic conductivities of the soils were not significantly affected by water salinity if these waters were the sole source of irrigation water. However, small additions of distilled water, assuming simulated to rain, to soils previously equilibrated with the saline waters significantly decreased soil permeability. Dispersion and short or long-distance transport of clay apparently clogged conducting pores when distilled water was introduced. Swelling was an important mechanism in reducing soil permeability only in the clay soil. The data suggest that, when saline water is the dominant irrigation source and is supplemented by rain, (1) all saline waters could be used on very sandy soils, (2) no saline waters should be used on very heavy soils, and (3) slightly saline, but not very saline, waters could be used on medium-textured soils.

  • PDF

The Processing of Causative and Passive Verbs in Korean (한국어의 사.피동문 처리에 관한 연구:실어증 환자의 처리 양상을 바탕으로)

  • 문영선;김동휘;남기춘
    • Proceedings of the Korean Society for Cognitive Science Conference
    • /
    • 2000.05a
    • /
    • pp.267-272
    • /
    • 2000
  • 본 연구에서는 한국어의 사·피동문을 실어증 환자가 처리하는 양상에 대하여 살펴보았다. 한국어의 사·피동문은 용언에 파생접사가 붙어 이루어지는 경우와 '-게 하다'나 '-어 지다'와 같이 구문 변형으로 하여, 실어증 환자에게 실험을 하였다. 실험에 참여한 환자는 명칭성 실어증 환자, 이해성 실어증 환자, 표현성 실어증 환자, 전반성 실어증 환자로 구성되어 있다. 본 실험에서는 단어 채워 넣기 과제(word completion task)를 사용하였다. 명칭성 실어증 환자의 경우 피동에서는 처리 오류를 보이는 반면, 사동에는 아무런 문제도 보이지 않았다. 표현성 실어증 환자의 경우, <피동-비변형>에서 오류를 많이 보였다. 이를 통해 한국어의 사·피동은 영어와 달리 통사상의 문제가 아니라는 결론을 내릴 수 있다. 즉 이미 사·피동 접사에 의해 파생된 단어가 어휘부에 저장되어 있고, 각 단어의 논항 정보에 따라 문장이 생성되는 것이다. 표현성 실어증 환자가 피동의 비변형에서 지배적인 오류를 보이는 것은 피동의 비변형이 타동사로서 변형인 피동형에 비해 하나의 논항을 더 취하기 때문이다. 이해성 실어증 환자의 경우 사·피동 생성에 별 어려움을 보이지 않았다. 이는 이해성 실어증 환자가 개별 어휘의 논항 정보에 손실을 적게 입고 있음을 시사하는 결과이다. 본 연구에서는 서로 다른 유형을 보이는 환자들을 대상으로 한국어의 사·피동의 처리양상을 대조한 결과, 첫재 사·피동은 서로 다른 통사, 의미상의 처리 양상을 보이고 있고, 둘째 파생접사가 결합된 형태로 어휘부에 저장되어 있는 개별 사·피동사에 의해 형성되는 것임을 확인하였다.d CO2 quantity causes flame temperature to fall since at high strain retes diluent effect is prevailing and at low strain rates the products inhibits chain branching. It is also found that the contribution of NO production by N2O and NO2 mechanisms are negligible and that thermal mechanism is concentrate on only the reaction zone. As strain rate and CO2 quantity increase, NO production is remarkably augmented.our 10%를 대용한 것이 무첨가한 것보다 많이 단단해졌음을 알 수 있었다. 혼합중의 반죽의 조사형 전자현미경 관찰로 amarans flour로 대체한 gluten이 단단해졌음을 알수 있었다. 유화제 stearly 칼슘, 혹은 hemicellulase를 amarans 10% 대체한 밀가루에 첨가하면 확연히 비용적을 증대시킬 수 있다는 사실을 알 수 있었다. quinoa는 명아주과 Chenopodium에 속하고 페루, 볼리비아 등의 고산지에서 재배 되어지는 것을 시료로 사용하였다. quinoa 분말은 중량의 5-20%을 quinoa를 대체하고 더욱이 분말중량에 대하여 0-200ppm의 lipase를 lipid(밀가루의 2-3배)에 대하여 품질개량제로서 이용했다.

  • PDF

Predictive Factors of Blood Transfusion Requirement in Blunt Trauma Patients Admitted to the Emergency Room (응급실에 내원한 둔상환자의 수혈 필요성 예측인자)

  • Oh, Ji Sun;Kim, Hyung Min;Choi, Se Min;Choi, Kyoung Ho;Hong, Tae Yong;Park, Kyu Nam;So, Byung Hak
    • Journal of Trauma and Injury
    • /
    • v.22 no.2
    • /
    • pp.218-226
    • /
    • 2009
  • Purpose: In multiple blunt trauma patients, transfusion may be a significant therapeutic adjunct to non-operative management. The blood products must be expedited and efficiently to patients in impending shock caused by hemorrhage or traumatic coagulopathy, but the decision to perform blood transfusion has been made empirically, based on the clinician' and has not been guided by objective parameters, but own opinion, that may result in an underestimate of or a failure to detect bleeding, in delayed transfusion, and in a reduced outcome. This article presents quickly assessable predictive factors for determining if a blood transfusion is required to improve outcomes in multiple blunt trauma patients admitted to the emergency room. Methods: In a retrospective review of 282 multiple blunt trauma patients who visited our emergency center by emergency rescuer during a 1-year period, possible factors predictive of the need for a blood transfusion were subjected to univariate and multivariate logistic regression analysis. Results: Of blunt trauma patients, 9.2% (26/282), received red blood cells in the first 24 hours of care. Univariate analysis revealed significant associations between blood transfused and heart rate (HR) > 100 beats/min, respiratory rate (RR) > 20 breaths/min, Glasgow Coma Scale (GCS) < 14, Revised Trauma Score (RTS) < 11, white blood cell count (WBC) < 4000 or > 10000, and initial abnormal portable trauma series (Cspine lateral, chest AP, pelvis AP). A multiple regression analysis, with a correction for diagnosis, identified HR > 100 beats/min (EXP 3.2), GCS < 14 (EXP 4.1), and abnormal trauma series (EXP 2.9), as independent predictors. Conclusion: In our study, systolic blood pressure (SBP) < 90 mmHg, old age > 65 years, hemoglobin < 13g/dL, mechanism of injury were poor predictors of early blood transfusion. Initial abnormal portable trauma series, HR > 100 beats/min, and GCS < 14 were quickly assessable useful factors for predicting a need for early blood transfusion in blunt trauma patients visiting the emergency room.

Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups

  • Lee, Jeong Woo;Kwon, O Hyun;Kim, Taek Kyun;Cho, Young Kyoo;Choi, Kang Young;Chung, Ho Yun;Cho, Byung Chae;Yang, Jung Dug;Shin, Jun Ho
    • Archives of Plastic Surgery
    • /
    • v.40 no.5
    • /
    • pp.530-535
    • /
    • 2013
  • Background Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400${\times}10^3$ cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process. However, even though PRP is widely used, the mechanism or actual effect is presently unclear. Therefore, this study was performed to investigate the levels of growth factors and platelet concentration rate. Methods Autologous blood for preparing PRP was obtained from healthy subjects aged 25 to 35 years. The samples were divided into 4 experimental groups (inactivated whole blood, inactivated PRP, activated whole blood with thrombin and calcium chloride, and activated PRP). The platelet counts in the blood were analyzed and the growth factors were quantitatively measured. A statistical analysis was performed by using Dunn's multiple comparison test. Results In the blood cell analysis, the platelet count of the PRP group was approximately 4.25 times higher than that of the whole blood group. In the quantitative analysis of growth factors, the platelet-derived growth factor (PDGF)-AB, PDGF-BB, and transforming growth factor-${\beta}$ of the inactivated and activated PRP groups were higher than those of the inactivated and activated whole blood groups (P<0.05). Conclusions In this study, the platelet count and the levels of PDGF-AB and PDGF-BB in the PRP were determined. Further, more research is required on the bioactivity level of the growth factors secreted during the process of PRP preparation and the potency of growth factors that can be exerted physiologically in vivo.

Effect of Epidermal Growth Factor (EGF) and anti-EGF on Early Embryonic Development in Mice (Epidermal Growth Factor (EGF)와 anti-EGF가 생쥐배아의 발생에 미치는 영향)

  • 변혜경;이호준
    • Korean Journal of Animal Reproduction
    • /
    • v.21 no.1
    • /
    • pp.61-69
    • /
    • 1997
  • The present study was carried out to investigate the effects of EGF and anti-EGF on early embryonic development and hatching in mice. Developmental and hatching rates of mouse em-bryos from 2-cell to morular stage which were cultured in Ham's FlO medium supplemented with EGF (1-1,000 ng/ml) or anti-EGF (whole serum diluted from 1:10 to 1:1,000) were compared to those of control When mouse early 2-cell embryos were cultured in the EGF supplemented medium, blastulation was accelerated compared with control. Hatching rate was also significantly (p

  • PDF

Functional Analysis of an Antibiotic Regulatory Gene, afsR2 in S. lividans through DNA microarray System (DNA 마이크로어레이 시스템 분석을 통한 S. lividans 유래 항생제 조절유전자 afsR2 기능 분석)

  • Kim, Chang-Young;Noh, Jun-Hee;Lee, Han-Na;Kim, Eung-Soo
    • KSBB Journal
    • /
    • v.24 no.3
    • /
    • pp.259-266
    • /
    • 2009
  • AfsR2 in Streptomyces lividans, a 63-amino acid protein with limited sequence homology to Streptomyces sigma factors, has been known for a global regulatory protein stimulating multiple antibiotic biosynthetic pathways. Although the detailed regulatory mechanism of AfsK-AfsR-AfsR2 system has been well characterized, very little information about the AfsR2-dependent down-stream regulatory genes were characterized. Recently, the null mutant of afsS in S. coelicolor (the identical ortholog of afsR2) has been characterized through DNA microarray system, revealing that afsS deletion regulated several genes involved in antibiotic biosynthesis as well as phosphate-starvation. Through comparative DNA microarray analysis of afsR2-overexpressed S. lividans, here we also identify several afsR2-dependent genes involved in phosphate starvation, morphological differentiation, and antibiotic regulation in S. lividans, confirming that the AfsR2 plays an important pleiotrophic regulatory role in Streptomyces species.

Speciation of the Two Species of the Genus Hyla (Anura) in Korea (한국산 청개구리속 2조의 종분화에 관한 연구)

  • 양서영;박병상
    • The Korean Journal of Zoology
    • /
    • v.31 no.1
    • /
    • pp.11-20
    • /
    • 1988
  • A comparison between two species of Hyla japonica and H. suweonesis in Korea was carried out to clarify their morphological, genetic and ecological differences, to estimate presumed divergent time between them, and to elucidate their probable process and mechanism of speciation. The results are as follows; 1.The breeding season of H. japonica was earlier than that of H. suweonensis about one and half months. 2.H.japonica was distributed all over the country, while H. suweonensis was restricted in Kyonggi plains. 3.On the extemal morphometric characters, differences were hardiy seen between two species. But on the discriminant function analysis, there was apparent differences between them. 4.Genic variation based on 24 loci showed that H. japonica populations were about two fold more variable than that of H. suweonensis populations. 5.Genetic relatedness between two species was rather remote (S =0.520, D=0.634) 6.Their presumed divergent time was estimated to be about three and a quarter mfllon years. It is presumed that H. suweonensis was originated from H. japonica during the period of late pleocene and early pleistocene. 7.Premating isolating mechanisrns (breeding season, mating call, and microhabitat segregation) may be operating to prevent gene ifow between them.

  • PDF

The Cytotoxic Effect of Oral Wet Wipes on Gingival Cells (시판 중인 구강청결티슈의 세포 독성 관찰)

  • Jung, Im-hee;Park, Ji Hyeon;Lee, Min Kyeng;Hwang, Young Sun
    • Journal of dental hygiene science
    • /
    • v.18 no.2
    • /
    • pp.76-84
    • /
    • 2018
  • Wet wipes are being increasingly used because of their convenience. Particularly, oral wet wipes are useful for regular cleaning of a baby's mouth after birth. Therefore, the consumption of oral wet wipes has increased over the past few years and a variety of products are commercially available. However, product information on safety is not sufficiently provided and still raises doubts regarding adverse effects. To confirm the safety of wet wipes as an oral hygiene item and provide information for their use, we investigated the cytotoxicity of oral wet wipes and verified the underlying mechanism. The anti-bacterial effect of oral wet wipes was analyzed using the disk diffusion method. The cytotoxic effects of oral wet wipes were observed based on morphological changes using microscopy and determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in gingival epithelial cells and gingival fibroblasts. Evaluation of apoptosis by oral wet wipes was explored using propidium iodide flow cytometric analysis and a terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuridine triphosphate (dUTP) nick-end labeling (TUNEL) assay. Apoptosis-related molecules were also analyzed using western blotting. Five types of oral wet wipes were tested, and two products from Fisher-Price and Dr. Kennedy revealed strong cytotoxic effects on gingiva epithelial cells and gingiva fibroblasts, although they also showed intense anti-bacterial effects on oral bacteria. Cell cycle arrest in the G2/M phase and apoptosis were observed based on treatment of extracts from Fisher-Price and Dr. KENNEDY. Relatively high TUNEL levels, reduction of proliferating cell nuclear antigen and cyclin-dependent kinase 4 expression, and fragmentation of poly (ADP-ribose) polymerase were also elucidated. These results suggest that commercial oral wet wipes could exert cytotoxic influences on oral tissue, although there are anti-bacterial effects, and careful attention is required, especially for infants and toddlers.

Fire Mechanism in Power Connection Points of Outlets and Suggestion of a New Identification Method (콘센트 전원 접속구 화재 발생 메커니즘 고찰과 새로운 감식 방법 제시)

  • Park, Jin-Young;Bang, Sun-Bae;Eun, Hee-Rim;Oh, Se-Hyeok;Lee, Yoo-Bin;Ko, Young-Ho
    • Fire Science and Engineering
    • /
    • v.34 no.3
    • /
    • pp.76-84
    • /
    • 2020
  • Most outlet fires occur around plug pins and plug pin receivers. However, no research has been conducted on ignitions at power connection points. This study confirms the possibility of ignition after incomplete connection, using a stranded wire, to the power connection point of an outlet. The experiment was divided into basic and reproducing experiments. The basic experiment confirmed the possibility of ignition according to the number of wire strands connected to the power connection point, and it identified the characteristics of the residue after the fire. In the reproducing experiment, lamps, vacuum cleaners, and heaters were connected to an outlet to check if the ignition at the connection advanced into a fire. The fire advanced due to the heat and arc generated at the connection point, and partial losses were identified in the U-type holder and clip. Accordingly, the results demonstrate that a fire may occur when the stranded wire is incompletely connected to the outlet. Moreover, it was confirmed that the cause of a fire can be determined based on the characteristics of the residue.

Chromophore formation and phosphorylation analysis of constitutively active rhodopsin mutants (Chromophore 형성과 rhodopsin kinase 활성을 이용한 항활성 로돕신 mutant의 분석)

  • Kim, Jong-Myoung
    • Journal of Life Science
    • /
    • v.17 no.6 s.86
    • /
    • pp.783-790
    • /
    • 2007
  • G protein coupled receptors (GPCRs) transmit various extracellular signals into the cells. Upon binding of the ligands, conformational changes in the extracellular and/or transmembrane (TM) domains of CPCRs were propagated into the cytoplasmic (CP) domain of the molecule leading to the activation of their cognate heterotrimeric C proteins and kinases. Constitutively active GPCR mutants causing the activation of C Protein signaling even in the absence of ligand binding are of interest for the study of activation mechanism of GPCRs. Two classes of constitutively active mutations, categorized by their effects on the salt bridge between Ell3 and K296, were found in the TM domain of rhodopsin. Opsin mutants containing combinations of the mutations were constructed to study the conformational changes required for the activation of rhodopsin. Rhodopsin chromophore regenerated with 11-cis-retinal showed a thermal stability inversely correlated with its constitutive activity. In contrast, rhodopsin mutants exhibited a binding affinity to an agonist, all-trans-retinal, in a constitutive activity-dependent manner. In order to test whether the conformational changes responsible for the activation of trans-ducin (Gt) are the same as the conformation required for the recognition of rhodopsin kinase, analysis of the mutants were carried out with phosphorylation by rhodopsin kinase. Rhodopsin mutants containing combinations of different classes of the mutations showed a strong synergistic effect on the phosphorylation of the mutants in the dark as similar to that of Gt activation. The results suggest that at least two or three kinds of segmental and independent conformational changes are required for the activation of rhodopsin and the conformational changes responsible for activating rhodopsin kinase and Gt are similar to each other.