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Use of a Miniplate for Skeletal Anchorage in the Forced Eruption of a Severely Impacted Mandibular Second Molar: Case Report (Miniplate를 골격성 고정원으로 사용한 심도있는 매복 하악 제2대구치의 맹출 치료: 증례보고)

  • Lim, Jae-Sung;Yoon, Hyun-Joong;Lee, Sang-Hwa
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.2
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    • pp.185-189
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    • 2011
  • Tooth impaction represents the stop of eruption by clinical and radiographical disturbance in eruption path or the dislocation of tooth germ. The most common factor in tooth eruption disorders are spacial deficiency with other causes reported to be odontogenic tumors, periodontal ligament injury, etc. Impaction of the mandibular second molar is relatively rare and reported in about 3 out of 1,000 people. Because the second molars tend to erupt in a mesial direction, this situation can lead to serious problems if untreated, including dental caries, periodontal disease and root resorption of the first molar. Treatment of this problem includes, surgical repositioning and orthodontic forced eruption. Because each procedure have the definite advantages and disadvantages, and influenced by circumferential environment, these have limits for successfu1 recovery as independent treatment. In a case at St. Mary's Hospital, we performed successful correction of a horizontal impacted mandibular second molar using a miniplate skeletal anchorage system. We introduce this treatment as a valid method for an impacted second molar and consider a oromaxillofacial surgeon's role in tooth movement treatment.

Oridonin Suppresses Proliferation of Human Ovarian Cancer Cells via Blockage of mTOR Signaling

  • Xia, Rong;Chen, Sun-Xiao;Qin, Qin;Chen, Yan;Zhang, Wei-Wei;Zhu, Rong-Rong;Deng, An-Mei
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.667-671
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    • 2016
  • Oridonin, an ent-kaurane diterpenoid compound isolated from the traditional Chinese herb Rabdosia rubescens, has shown various pharmacological and physiological effects such as anti-tumor, anti-bacterial, and anti-inflammatory properties. However, the effect of oridonin on human ovarian cancer cell lines has not been determined. In this study, we demonstrated that oridonin inhibited ovarian cancer cell proliferation, migration and invasion in a dose-dependent manner. Furthermore, we showed oridonin inhibited tumor growth of ovarian cancer cells (SKOV3) in vivo. We then assessed mechanisms and found that oridonin specifically abrogated the phosphorylation/activation of mTOR signaling. In summary, our results indicate that oridonin is a potential inhibitor of ovarian cancer by blocking the mTOR signaling pathway.

Analysis of Hydraulic Characteristics and Reduction of Bottom Velocity of Second Stilling Basin (2차 정수지의 수리특성 및 바닥 유속 저감효과 분석)

  • Jeong, Seokil;Lee, Ji Hun;Yoon, Jae-Seon;Lee, Seung Oh
    • Journal of the Korean Society of Safety
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    • v.33 no.5
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    • pp.134-140
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    • 2018
  • Scour in the downstream of hydraulic structures such as apron induces to collapse due to abruptly increasing rainfall and discharge in streams and reaches. This is because the forcible jet from overflowing is not sufficiently dissipated by existing energy dissipators, and it continues to sweep the bed materials during flood events. In this study, a second stilling basin was proposed as a countermeasure and the energy dissipation efficiency of this structure was analyzed using 3D-dimensional numerical analysis. First, results from previous research and hydraulic tests were used to verify the accuracy of the numerical model. It showed that the second stilling basin played a definite role in reducing the bottom velocity, comparing with diminishing the energy dissipation when numerical tests were conducted under scaled field conditions in Korea. This means that the second stilling basin can be a countermeasure against scour in downstream. If more efficiency analysis of the second stilling basin would be performed in terms of energy dissipator for various types of hydraulic jump, it would be an alternative solution to scouring issues.

Apoptosis of Colorectal Cancer UTC116 Cells Induced by Cantharidinate

  • Liu, Bin;Gao, Hai-Cheng;Xu, Jing-Wei;Cao, Hong;Fang, Xue-Dong;Gao, Hai-Mei;Qiao, Shi-Xing
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3705-3708
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    • 2012
  • Effects of Cantharidinate on apoptosis of human colorectal cancer UTC-116 cells were investigated by means of 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay, H and E staining, flow cytometry, and Raman Spectra analysis. The results showed Cantharidinate to exert inhibitory action on proliferation of human colorectal cancer UTC-116 cells, inducing apoptosis, arresting cells in G1 phase, with decline of S and G2 phases. In addition, the results of Raman spectrum showed significant changes in the UTC-116 cells chemical structure with stretching after the application of Cantharidinate. Taken together, these results suggest that the treatment of human colorectal cancer with Cantharidinate may be associated with multiple molecular mechanisms for apoptosis. Furthermore, similar to fluorouracil, Cantharidinate should be considered as novel assistant drug for controlling the growth of human colorectal cancer UTC-116 cells.

Nonionic Amphiphilic Surfactant Conjuncted Polyethyleneimine as a New and Highly Efficient Non-viral Gene Carrier

  • Yin, Dongfeng;Chu, Cang;Ding, Xueying;Gao, Jing;Zou, Hao;Gao, Shen
    • Macromolecular Research
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    • v.17 no.1
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    • pp.19-25
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    • 2009
  • In order to enhance the gene delivery efficiency and decrease the cytotoxicity of polyplexes, we synthesized Solutol-g-PEI by conjugating polyethyleneimine (PEI) to Solutol (polyoxyethylene (10) stearate), and evaluated its efficiency as a possible nonviral gene carrier candidate. Structural analysis of synthesized polymer was performed by using $^1H$-NMR. Gel retardation assay, particle sizes and zeta potential measurement confirmed that the new gene carrier formed a compact complex with plasmid DNA. The complexes were smaller than 150 nm, which implicated its potential for intracellular delivery. It showed lower cytotoxicity in three different cell lines (Hela, MCF-7, and HepG2) than PEI 25 kDa. pGL3-lus was used as a reporter gene, and the transfection efficiency was in vitro measured in Hela cells. Solutol-g-PEI showed much higher transfection efficiency than unmodified PEI 25 kDa.

A study of mandibular canal angle and location of mental foramen on the panoramic radiograph (파노라마방사선사진에서의 하악관의 각도와 이공의 위치에 관한 연구)

  • Choi, Hang-Moon
    • Imaging Science in Dentistry
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    • v.39 no.2
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    • pp.89-92
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    • 2009
  • Purpose: To assess the angle between mandibular canal and occlusal plane at each posterior tooth region and location of mental foramen on the panoramic radiographs. Materials and Methods: This study analysed 46 half-mandibles of panoramic radiographs. Inferior border of mandibular canal was traced. Occlusal plane was drawn from lingual cusp tip of the first premolar to distolingual cusp tip of the second molar. Perpendicular line from occlusal plane was drawn at each tooth region and then tangential lines were drawn from the crossing points at canal. the angle between occlusal plane and tangential line was measured. The location of mental foramen was also studied. According to the location of mental foramen, radiographs were divided into M (mesial) group and D (distal) group on the basis of the second premolar. and then inter-group analysis about mandibular canal angle was done. Results: The angles of mandibular canals were -17.7$^{\circ}$, -9.5$^{\circ}$, 8.2$^{\circ}$, 22.3$^{\circ}$, and 39.2$^{\circ}$at first premolar, second premolar, first molar, second molar, and third molar, respectively. The commonest position of the mental foramen was distal to the second premolar. Inter-group comparison showed statistically significant difference at the second premolar and the first molar(p<0.001). Conclusion: The knowledge of mandibular canal angle and location of mental foramen can help understanding the course of mandibular canal. (Korean J Oral Maxillofac Radiol 2009; 39: 89-92)

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Which Motivations Influence Consumer Behavior? : Focusing on Second-hand Distribution Platforms

  • Hong-Sub, SHIN;Eunji, CHOI;Jin-Hwan, KIM
    • Journal of Distribution Science
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    • v.21 no.3
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    • pp.123-134
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    • 2023
  • Purpose: The no-contact and economic downturn caused by COVID-19 have further grown the used market. The second-hand trading industry has established itself as a popular consumption culture, leading to exponential growth in the size of the market. This study aims to identify the types of shopping motivation for used products targeting Korean consumers, and to examine the relationship between shopping motivations for second-hand transactions, consumption values, and re-use intentions. Research design, data and methodology: The first study was conducted on 63 used trading platform users and the second study was conducted on 441 used trading platform users to identify the types of consumers' motivation for shopping for used products. Results: As a result of the first study, the shopping motivation types of Korean used product consumers were classified into convenience motivation, economic motivation, hedonistic motivation, information Acquisition motivation, and free time utilization motivation. As a result of the second study, it was found that convenience motivation had the greatest influence on functional values and hedonic motivation had the greatest influence on emotional values, and that functional values had a great influence on platform reuse intentions. Conclusions: This study provides practical implications for the establishment of marketing strategies for used trading platforms and academic implications for research related to used trading.

CERTAIN FORMULAS INVOLVING EULERIAN NUMBERS

  • Choi, Junesang
    • Honam Mathematical Journal
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    • v.35 no.3
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    • pp.373-379
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    • 2013
  • In contrast with numerous identities involving the binomial coefficients and the Stirling numbers of the first and second kinds, a few identities involving the Eulerian numbers have been known. The objective of this note is to present certain interesting and (presumably) new identities involving the Eulerian numbers by mainly making use of Worpitzky's identity.

COMPLEX FACTORIZATIONS OF THE GENERALIZED FIBONACCI SEQUENCES {qn}

  • JUN, SANG PYO
    • Korean Journal of Mathematics
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    • v.23 no.3
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    • pp.371-377
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    • 2015
  • In this note, we consider a generalized Fibonacci sequence {$q_n$}. Then give a connection between the sequence {$q_n$} and the Chebyshev polynomials of the second kind $U_n(x)$. With the aid of factorization of Chebyshev polynomials of the second kind $U_n(x)$, we derive the complex factorizations of the sequence {$q_n$}.

Radius of Starlikeness for Analytic Functions with Fixed Second Coefficient

  • Ali, Rosihan M.;Kumar, Virendra;Ravichandran, V.;Kumar, Shanmugam Sivaprasad
    • Kyungpook Mathematical Journal
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    • v.57 no.3
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    • pp.473-492
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    • 2017
  • Sharp radius constants for certain classes of normalized analytic functions with fixed second coefficient, to be in the classes of starlike functions of positive order, parabolic starlike functions, and Sokół-Stankiewicz starlike functions are obtained. Our results extend several earlier works.