• 대한치과교정학회지
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• 제49권6호
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• pp.404-412
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• 2019

Objective: To assess shear bond strength and failure mode (Adhesive Remnant Index, ARI) of orthodontic brackets bonded to polymethylmethacrylate (PMMA) blocks for computer-aided design/manufacture (CAD/CAM) fabrication of temporary restorations, following substrate chemical or mechanical treatment. Methods: Two types of PMMA blocks were tested: $CAD-Temp^{(R)}$ (VITA) and $Telio^{(R)}$ CAD (Ivoclar-Vivadent). The substrate was roughened with 320-grit sandpaper, simulating a fine-grit diamond bur. Two universal adhesives, Scotchbond Universal Adhesive (SU) and Assure Plus (AP), and a conventional adhesive, Transbond XT Primer (XTP; control), were used in combination with Transbond XT Paste to bond the brackets. Six experimental groups were formed: (1) $CAD-Temp^{(R)}/SU$; (2) $CAD-Temp^{(R)}/AP$; (3) $CAD-Temp^{(R)}/XTP$; (4) $Telio^{(R)}$ CAD/SU; (5) $Telio^{(R)}$ CAD/AP; (6) $Telio^{(R)}$ CAD/XTP. Shear bond strength and ARI were assessed. On 1 extra block for each PMMA-based material surfaces were roughened with 180-grit sandpaper, simulating a normal/medium-grit ($100{\mu}m$) diamond bur, and brackets were bonded. Shear bond strengths and ARI scores were compared with those of groups 3, 6. Results: On $CAD-Temp^{(R)}$ significantly higher bracket bond strengths than on $Telio^{(R)}$ CAD were recorded. With XTP significantly lower levels of adhesion were reached than using SU or AP. Roughening with a coarser bur resulted in a significant increase in adhesion. Conclusions: Bracket bonding to CAD/CAM PMMA can be promoted by grinding the substrate with a normal/medium-grit bur or by coating the intact surface with universal adhesives. With appropriate pretreatments, bracket adhesion to CAD/CAM PMMA temporary restorations can be enhanced to clinically satisfactory levels.

• Asian-Australasian Journal of Animal Sciences
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• 제18권7호
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• pp.966-972
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• 2005

A study to compare the effects of supplementing Delonix elata, Grewia similis, Tamarindus indica and sunflower seed cake on intake and growth rate of dual-purpose goats fed low quality Buffel grass (Cenchrus ciliaris) hay was carried out. Twenty-eight male goats aged five to seven months (mean weight 12.93${\pm}$3.94 kg) were randomly allocated to four dietary groups in a completely randomised design. The diets were hay plus Grewia similis, hay plus Delonix elata, hay plus Tamarindus indica and hay plus sunflower seed cake. All diets were supplemented with maize bran. The experimental period was 90 days. Voluntary dry matter intake of the supplements was higher for Tamarindus indica (275.5 g/day) and Grewia similis (201.8 g/day) and lowest for sunflower seed cake (81g/day). Goats supplemented with Grewia similis had the highest hay intake (183.8 g/day) while those supplemented with sunflower seed cake had the lowest hay intake (98.9 g/day). Animals fed browse supplements gained significantly more weight (p<0.001) than those with sunflower seed cake. There were no significant differences in live weight change between goats fed the different browses. However, those fed Tamarindus indica gained an average of 20.79 g/d which was slightly higher than the gains for those on Grewia similis and Delonix elata while those fed sunflower seed cake lost weight. Correspondingly, goats supplemented with browse leaf meals had higher feed conversion ratios than those supplemented with sunflower seed cake and required 23.91 to 35.06 g DM of feed to produce one g of weight gain per day. In a separate study, the DM disappearance pattern indicated that Grewia similis and Delonix elata were highly degradable compared to Tamarindus indica. At 24 h of incubation, DM degradability was 627, 588 and 345 g/kg DM for Grewia similis, Delonix elata and Tamarindus indica, respectively. In another study in vivo DM digestibility ranged from 46.1% (for hay alone) to 56.2% (for hay plus Grewia similis). It was concluded that the addition of Tamarindus indica, Grewia similis and Delonix elata leaf meals to Cenchrus ciliaris hay resulted in increased total DM intake, in vivo digestibility and growth rate. Therefore, leaf meals of indigenous browses particularly Tamarindus indica and Grewia similis could be used as supplementary feeds for small ruminants grazing on poor quality roughages during the dry season rather than use of expensive, less effective and intermittently available sunflower seed cake.

• International Journal of Oral Biology
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• 제44권2호
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• pp.50-54
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• 2019

Melatonin is a neurotransmitter that modulates various physiological phenomena including regulation and maintenance of the circadian rhythm. Nicotinic acetylcholine receptors (nAChRs) play an important role in oral functions including orofacial muscle contraction, salivary secretion, and tooth development. However, knowledge regarding physiological crosstalk between melatonin and nAChRs is limited. In the present study, the melatonin-mediated modulation of nAChR functions using bovine adrenal chromaffin cells, a representative model for the study of nAChRs, was investigated. Melatonin inhibited the nicotinic agonist dimethylphenylpiperazinium (DMPP) iodide-induced cytosolic free $Ca^{2+}$ concentration ($[Ca^{2+}]_i$) increase and norepinephrine secretion in a concentration-dependent manner. The inhibitory effect of melatonin on the DMPP-induced $[Ca^{2+}]_i$ increase was observed when the melatonin treatment was performed simultaneously with DMPP. The results indicate that melatonin inhibits nAChR functions in both peripheral and central nervous systems.

• 한국산림과학회지
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• 제69권1호
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• pp.1-5
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• 1985

잣나무 수형목(秀型木) 23클론에 대(對)한 수고(樹高), 흉고직경(胸高直徑), 수관폭(樹冠幅), 가지길이 및 가지 직경(直徑)의 생장특성(生長特性)을 측정(測定)하여 다음과 같은 결과(結果)을 얻었다. 1) 생장(生長)이 가장 우수(優秀)한 클론은 가장 불량(不良)한 클론에 비(比)하여 수고(樹高)는 41%, 흉고직경(胸高直徑)은 81%, 수관폭(樹冠幅)은 50%, 가지길이는 55% 및 가지직경(直徑)은 83%의 양호(良好)한 생장(生長)을 보였다. 2) 각(各) 생장특성(生長特性)은 클론간(間)에 유의차(有意差)가 있었으며, 각(各) 생장특성간(生長特性間)의 상관(相關)은 고도(高度)의 정(正)의 상관(相關)을 나타냈다 ($r=0.418^*{\sim}0.917^{**}$). 3) 각(各) 생장특성(生長特性)에 대(對)한 광의(廣義)의 유전력(遺傳力)은 수고(樹高)에서 0.46, 흉고직경(胸高直徑)에서 0.45, 수관폭(樹冠幅)에서 0.28, 가지길이에서 0.26 및 가지직경(直徑)에서 0.18로 추정(推定)되었다. 4) 개량효과(改良効果)는 23 클론 중(中) 생장(生長)이 우수(優秀)한 3 클론을 각(各) 특성별(特性別)로 선발(選拔)하여 4.1%~11.1%까지 예측(豫測)할 수 있었다.

• 한국산림과학회지
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• 제96권3호
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• pp.317-324
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• 2007

종자 공급 방안 개선에 필요한 기초 자료 획득을 위해 소나무 우량 임분 3개소를 대상으로 2003년부터 2006년까지 구과 생산량에 따른 종자 및 발아 특성을 분석한 결과 다음과 같은 결과를 얻었다. 구과 생산량은 2년을 주기로 하여 풍 흉 상태를 보였다. 주요 종자 특성 중 종자 생산 능력과 충실 종자율은 대체적으로 구과 생산량과 유사한 경향을 보인 반면 성숙 종자율과 종자 효율은 반대 경향을 나타내었다. 종자 특성과 구과 생산량과의 회귀분석 결과에서도 종자 생산 능력 ($R^2=0.682$, p<0.01)과 충실 종자율($R^2=0.l61$, non-significant)은 정(+)의 경향을, 성숙 종자율($R^2=0.418$, p<0.05)과 종자 효율($R^2=0.308$, non-significant)은 부(-)의 경향을 나타내었다. 발아 특성에 있어서 발아율은 대체적으로 구과 생산량과 유사한 경향으로 나타났으나, 평균 발아 일수는 반대의 경향을 보였다. 회귀분석결과에서도 발아율은 구과 생산량과 정(+)의 관계($R^2=0.576$, p<0.01)를 보인 반면, 평균 발아 일수는 부(-)의 관계($R^2=0.400$, p<0.05)를 보여 구과 생산량이 많은 시기에 이를 채취하여 사용할 때 발아율도 높고 발아에 소요되는 기간도 짧아져 즉, 발아 효율이 높아짐을 알 수 있었다.

• 한국균학회지
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• 제15권4호
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• pp.250-253
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• 1987

원형질체내에 외래유전물질 도입에 의한 균주 개발의 가능성 검토의 일환으로 사철느타리의 원형질체로부터 핵을 분리하여 느타리의 원형질체내로 전이하여 얻은 결과는 다음과 같았다. 1. 핵전이주는 크게 3가지 type으로 구분되었는데 type 1은 아주 빠른 균사생장과 clamp connection를 형성하지 않으며 CM+benomyl에서 균총분리가 나타남으로서 이질이배체로 사료되었다. type 2는 주된 핵전이주로서 모균주와 비슷하거나 다소 빠른 균사생장과 clamp connection을 지녀 자실체를 형성하였으며 heterokaryon으로서 원형질체 융합주와 유사하였다. 그러고 type 3은 핵 또는 염색체 단편의 전이로 clamp connection를 지니지 않고 아주 느리거나 MM에서 생육이 거의 불가능한 균주였다. 2. 핵전이주 및 모균주를 전기영동법으로 esterase 동위효소 pattern을 조사한 결과 핵전이주는 모균주와 구별되었는데 type 1인 이질이배체는 새로운 band를 나타내었으며, type 2와 type 3은 모균주들을 합한 것으로 보였다.

• 대한방사선기술학회지:방사선기술과학
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• 제39권2호
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• pp.171-176
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• 2016

영상화 품질향상은 방사선 치료영역과 진단영역의 영상화 검사와 같이 quality assurance (QA) 장비들의 특성평가에 매우 중요한 요소이다. 본 연구의 목적은 치료장비의 megavoltage X-ray 에너지를 사용하여 측정방법에 있어서 NPS에 대한 수평, 수직적인 방법에 대한 측정결과를 비교 평가하는 것이다. 잡음전력스펙트럼 평가 방법들은 국제 전기 규격 international electro-technical commission (IEC 62220-1) 기준을 사용하여 치료 영역에 적용되었다. 사용한 전자포털 영상장치(electronic portal imaging device, EPID)는 Siemens BEAMVIEW$^{PLUS}$, Elekta iViewGT 그리고 Varian Clinac$^R$ iX aS1000이었다. 데이터들로부터 각각의 주파수 값에 대응하는 노이즈 값들의 평균에 대해서, 각각의 주파수 별로 대응해서 표현하였으며, 수평 수직되어있는 주파수별 평균값의 노이즈값을 합산해서 정량적으로 장비마다 비교 평가하였다. 결과값은 Elekta iView에서 4가지 방법론에 의한 가로방향에서의 horizontal측정된 NPS값과 vertical 세로방향에서의 측정치는 비슷한 경향성에 따라서 horizontal과 vertical값은 3~5%정도의 차이가 있었으며, Siemens BEAMVIEW$^{PLUS}$, Varian Clinac$^R$ iX aS1000에서 horizontal측정된 NPS값과 vertical 측정된 NPS값은 편차의 차이가 전체값의 평균으로 했을 시 horizontal과 vertical값은 15%정도의 차이가 나타남을 보였다. 본 연구에서는 수평 수직되어있는 주파수별 평균값의 노이즈값을 합산해서 정량적으로 장비마다 비교 평가하였으며, 정량적인 평가방안을 제시하였다는 점을 둘 수 있다.

• Restorative Dentistry and Endodontics
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• 제46권1호
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• pp.5.1-5.13
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• 2021

Objectives: The aim of the current study was to assess whether the amount of extruded debris differs for straight and severely curved root canals during retreatment using H-files, R-Endo, Reciproc and ProTaper Universal Retreatment (PTU-R) files. Additionally, the area of residual filling material was evaluated. Materials and Methods: Severely curved (n = 104) and straight (n = 104) root canals of maxillary molar teeth were prepared with WaveOne Primary file and obturated with gutta-percha and AH Plus sealer. Root canal filling materials were removed with one of the preparation techniques: group 1: H-file; group 2: R-Endo; group 3: Reciproc; group 4: PTU-R (n = 26). The amount of extruded material and the area of the residual filling material was measured. The data were analyzed with 2-way analysis of variance (ANOVA) and 1-way ANOVA at the 0.05 significance level. Results: Except for Reciproc group (p > 0.05), PTU-R, R-Endo, and H-file systems extruded significantly more debris in severely curved canals (p < 0.05). Each file system caused more residual filling material in severely curved canals than in straight ones (p < 0.05). Conclusions: All instruments used in this study caused apical debris extrusion. Root canal curvature had an effect on extruded debris, except for Reciproc system. Clinicians should be aware that the difficult morphology of the severely curved root canals is a factor increasing the amount of extruded debris during the retreatment procedure.

• 대한한의학회지
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• 제21권3호
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• pp.20-30
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• 2000

Objective : This experiment was performed in order to study the effect of an aqueous extract of Salviae radix root(SRRAE) on NO production and NOS gene induction from macrophages Methods : To investigate dose-dependent effects of SRRAE for NO release on the $rIFN-{\gamma}-treated$ macrophages, the cells were incubated for 6 hrs in a medium containing $rIFN-{\gamma}$ (5 U/ml), stimulated with SRRAE and incubated in a CO2 incubator. The cells were treated with 5 U/ml $rIFN-{\gamma}$ plus 100 g/ml of SRRAE, Then, the cells were incubated with various concentrations of NGMMA at $37^{\circ}C$ for 48 hrs, Results : SRRAE had no effect on NO production by itself, whereas recombinant $interferon-{\gamma}(rIFN-{\gamma})$ alone showed modest activity, When SRRAE was used in combination with $rIFN-{\gamma}$, there was a marked cooperative induction of NO production in a dose-dependent manner. The optimal effect of SRRAE on NO production was shown at 6hrs after treatment with $rIFN-{\gamma}$. The SRRAE-induced production of NO was inhibited by NG-monomethyl- L-arginine(NGMMA) and arginase. $rIFN-{\gamma}$ in combination with SRRAE showed a marked increase of the expression of the inducible NOS(iNOS) gene. In addition, the effect of SRRAE was mainly dependent on the SRRAE-induced tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ secretion. Conclusions : SRRAE induces NO production from macrophages as a result of SRRAE-induced $TNF-{\alpha}$ secretion. SRRAE may provide a second signal for synergistic induction of NO production in macrophages already induced to express iNOS gene by $rIFN-{\gamma}$.

• Asian-Australasian Journal of Animal Sciences
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• 제23권5호
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• pp.630-639
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• 2010

Immune response and yolk cholesterol are crucial factors for commercial chicken producers. The objectives of this study were to investigate the effect of selenium-enriched Japanese radish sprouts (Se-enriched JRS) and R. capsulatus synergistically on immune response and cholesterol in laying hens. A total of 50 laying hens (20-wk old) were assigned to 5 dietary treatment groups, and fed diets supplemented with 2.5 ${\mu}g/kg$, 5 ${\mu}g/kg$, 10 ${\mu}g/kg$ Se-enriched JRS and 5 ${\mu}g/kg$ Se-enriched JRS+R. capsulatus (0.02%). Egg production and yolk color were significantly improved by the supplementation of Se-enriched JRS+R. capsulatus in the layer diet (p<0.05). Compared to the control, serum cholesterol concentration and triglyceride levels were decreased by all the treatments (p<0.05). After 8-wk of the experiment, supplementation of 5 ${\mu}g/kg$, 10 ${\mu}g/kg$ and Se-enriched JRS+R. capsulatus significantly reduced yolk cholesterol and triglycerides, while the greatest reduction was observed when R. capsulatus was incorporated with Se-enriched JRS. Spleen, bursa and thymus weight were significantly increased by both the 5 ${\mu}g/kg$ and 10 ${\mu}g/kg$ Se-enriched JRS. Compared to the control, supplementation of 5 ${\mu}g/kg$ and 10 ${\mu}g/kg$ Se-enriched JRS significantly increased serum IgG and yolk IgY concentration and foot web index activity by Newcastle Disease Virus (p<0.05). After 4-wk and 8-wk of supplementation, the highest number of leukocytes was observed with Se-enriched JRS+R. capsulatus (p<0.05). The highest concentration of serum and yolk Se was found in Se-enriched JRS plus R. capsulatus treatment. Combined dietary supplementation of Se-enriched JRS and R. capsulatus might be beneficial for better health, disease protection and overall production performance.