• Steel and Composite Structures
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• v.43 no.1
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• pp.31-54
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• 2022

This paper is concerned with the buckling behavior of functionally graded graphene reinforced porous nanocomposite beams based on the finite element method (FEM) using two variables trigonometric shear deformation theory. Both Young's modulus and material density of the FGP beam element are simultaneously considered as grading through the thickness of the beam. The finite element approach is developed using a nonlocal strain gradient theory. The governing equations derived here are solved introducing a 3-nodes beam element, and then the critical buckling load is calculated with different porosity distributions and GPL dispersion patterns. After a convergence and validation study to verify the accuracy of the present model, a comprehensive parametric study is carried out, with a particular focus on the effects of weight fraction, distribution pattern of GPL reinforcements on the Buckling behavior of the nanocomposite beam. The effects of various structural parameters such as the dispersion patterns for the graphene and porosity, thickness ratio, boundary conditions, and nonlocal and strain gradient parameters are brought out. The results indicate that porosity distribution and GPL pattern have significant effects on the response of the nanocomposite beams, and the results allows to identify the most effective way to achieve improved buckling behavior of the porous nanocomposite beam.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.416-418
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• 2022

Glioma is a type of brain tumor that occurs in glial cells and is classified into two types: high hrade hlioma with a poor prognosis and low grade glioma. Magnetic resonance imaging (MRI) as a non-invasive method is widely used in glioma diagnosis research. Studies to obtain complementary information by combining multiple modalities to overcome the incomplete information limitation of single modality are being conducted. In this study, we developed a 3D CNN-based model that applied input-level fusion to MRI of four modalities (T1, T1Gd, T2, T2-FLAIR). The trained model showed classification performance of 0.8926 accuracy, 0.9688 sensitivity, 0.6400 specificity, and 0.9467 AUC on the validation data. Through this, it was confirmed that the grade of glioma was effectively classified by learning the internal relationship between various modalities.

• Investigative Magnetic Resonance Imaging
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• v.11 no.2
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• pp.87-94
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• 2007

Purpose: The purpose of this study was to evaluate the usefulness of fast inversion recovery (FIR) and magnetization-prepared three dimensional gradient echo sequence (3D GRE) T1-weighted sequences for neonatal brain imaging compared with spin echo (SE) sequence in a 3T MR unit. Materials and Methods: T1-weighted axial SE, FIR and 3D GRE sequences were evaluated from 3T brain MR imaging in 20 neonates. The signal-to-noise ratio (SNR) of different tissues was measured and contrast-to-noise ratios (CNR) were determined and compared in each of the sequences. Visual analysis was carried out by grading gray-white matter differentiation, myelination, and artifacts. The Wilcoxon signed ranked test was used for evaluation of the statistical significance of CNR differences between the sequences. Results: Among the three sequences, the 3D GRE had the best SNRs. CNRs obtained with FIR and 3D GRE were statistically superior to those obtained with SE; these CNRs were better on the 3D GRE compared to the FIR. Gray to white matter differentiation and myelination were better delineated on the FIR and 3D GRE than the SE. However, motion artifacts were more commonly observed on the 3D GRE and flow-related artifacts of vessels were frequently seen on the FIR. Conclusion: FIR and 3D GRE are valuable alternative T1-weighted sequences to conventional SE imaging of the neonatal brain at 3T providing superior image quality.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6335-6338
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• 2015

Background: Cancers have dysfunctional redox regulation resulting in production of reactive oxygen species (ROS), damaging DNA, RNA and free NTPs, and causing the accumulation of oxidative nucleic acids in cytoplasm. The major types are 8-oxo-7,8-dihydroguanine(8-oxoGsn) in RNA and 8-oxo-7,8-dihydro-2' deoxyguanosine(8-oxodGsn) in Mt-DNA. The MTH1 protein sanitizes oxidized nucleotide pools from NTPs to monophosphates, preventing the occurrence of transversion mutations. This study concerned cytoplasmic 8-oxodGsn/Gsn and MTH1 expression in gastric cancer and para-cancer tissues and elucidated roles of nucleic-acid oxidation and anti-oxidation. Materials and Methods: A polymer HRP detection system was used to detect 8-oxo-Gsn/dGsn and MTH1 expression in 51 gastric cancer and para-cancer tissue samples. Analyses of patient clinical and pathological data were also performed. Results: The expression of MTH1 and the 8-oxo-dGsn/Gsn ratio were significantly higher in cancer tissues than para-cancer tissues (P<0.05). Cytoplasmic 8-oxo-Gsn and MTH1 were both found to positively correlate (P<0.05) with tumor differentiation, while no significant associations were found with gender, age, invasion depth, lymph node metastasis and clinical stage (P>0.05). Conclusions: We found 8-oxo-dGsn/Gsn and MTH1 are both highly expressed in gastric cancer tissues, especially in well differentiated lesions. In addition, oxidated mtDNA is prevalently expressed in gastric cancers, while 8-oxo-Gsn expression in cytoplasmic RNA is a bit lower, but more selectively.

• Clinics in Shoulder and Elbow
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• v.25 no.2
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• pp.112-120
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• 2022

Background: The prognostic factors for patients with full-thickness rotator cuff tears (RCTs) include tear size, muscle atrophy and fatty infiltration. However, the influence of early coexisting degenerative changes on RCT outcomes is unappreciated. The purpose of this study was to calculate the impact that pre-existing partial glenohumeral cartilaginous changes have on patients undergoing arthroscopic RCT repair. Methods: A study of 54 patients undergoing arthroscopic RCT repair was undertaken. The presence of co-existing patches of glenohumeral degenerative cartilaginous changes and RCT size was recorded at surgery. Pre- and postoperative outcomes were assessed using traditional (Oxford Shoulder Score [OSS], 5-level EuroQol-5D [EQ-5D-5L] questionnaire and EuroQol visual analog scale [EQ-VAS]) and patient-centric re-formatted prisms. Outcomes were assessed as an entire dataset, and sub-group analysis was performed according to the grade of co-existing arthritis and tear size. Results: Significant improvements (p<0.05) in clinical outcomes were recognized when assessed using either the traditional or reformatted prisms (average % improvements in OSS, EQ-5D-5L and EQ-VAS were 47%, 33% and 43%, respectively; average improvements in pain, function, and psychological well-being were 48%, 33% and, 29%, respectively). Positive gain was noted in all sub-groups of arthritic grading and tear size. Conclusions: Good clinical outcomes can be achieved following RCT repair even in the presence of local partial degenerative cartilage changes and advancing tear size. These benefits are patient-centered but require RCT repairability.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.867-870
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• 2014

Purpose: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) ependymoma data to identify predictive models and potential disparity in outcome. Materials and Methods: This study analyzed socio-economic, staging and treatment factors available in the SEER database for ependymoma. For the risk modeling, each factor was fitted by a Generalized Linear Model to predict the outcome ('brain and other nervous systems' specific death in yes/no). The area under the receiver operating characteristic curve (ROC) was computed. Similar strata were combined to construct the most parsimonious models. A random sampling algorithm was used to estimate the modeling errors. Risk of ependymoma death was computed for the predictors for comparison. Results: A total of 3,500 patients diagnosed from 1973 to 2009 were included in this study. The mean follow up time (S.D.) was 79.8 (82.3) months. Some 46% of the patients were female. The mean (S.D.) age was 34.4 (22.8) years. Age was the most predictive factor of outcome. Unknown grade demonstrated a 15% risk of cause specific death compared to 9% for grades I and II, and 36% for grades III and IV. A 5-tiered grade model (with a ROC area 0.48) was optimized to a 3-tiered model (with ROC area of 0.53). This ROC area tied for the second with that for surgery. African-American patients had 21.5% risk of death compared with 16.6% for the others. Some 72.7% of patient who did not get RT had cerebellar or spinal ependymoma. Patients undergoing surgery had 16.3% risk of death, as compared to 23.7% among those who did not have surgery. Conclusion: Grading ependymoma may dramatically improve modeling of data. RT is under used for cerebellum and spinal cord ependymoma and it may be a potential way to improve outcome.

• Journal of the Korean Home Economics Association
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• v.35 no.5
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• pp.249-264
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• 1997

The purpose of this study was to provide the reference information for user and potential users of apparel CAD system is Korea. Two interviews were carried out for the study. The apparel CAD system of Assyst, Gerber and Yuka was selected for technical comparative study. The results were as follows: 1. The future development of the apparel CAD system is the transfer of the developed pattern design from a 3D design system and of CIM concept. 2. The share of data is working closely in a module function. So the Assyst system provide connectivity and communication between all apparel CAD system's module and other automation programs. This system is suitable for CIM production line. 3. The Gerber system is developed the Apparel CAD system which is given by the CAM system's technical ability. This system is given high insurance of ability to the service and data transportation with other systems from users in the Korea. 4. The Yuka system is developed pattern making by the Apparel CAD system. This system's different methods which is compared with other systems are the split grading and auto pattern making. So this system is suitable for users which want to product many items and a little amount garment by using the Apparel CAD system.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.22 no.5
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• pp.436-442
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• 2009

This paper describes a study on the design of compact polymer bushing with inner control shield. In the bushing, a high electric stress occurred between field shaper and central conductor by the closely space. Also coaxial cylindrical shield has a great height along the axis to control an electric field. Consequently, all the potentials are raised axially along the field shaper and electric stress is concentrated on a part of the surface of the FRP tube near the upper end of the field shaper. In accordance, the field control can be achieved by means of the designs of such inner control shields. The floating and ring shield designs was decreased electric field concentration at critical parts of the bushing. The shield gaps is formed between field shaper and ring shield. Accordance equipotential lines extend through gaps. As a result, the resulting electrical stress are thus reduced in the range $17{\sim}23%$ in the bushing with floating and ring shield designs. Maxwell 2D simulator based on the boundary element method was also introduced in order to verify the reliability of the polymer bushing. The optimized design uses internal elements for electric stress grading at critical parts of the bushing.

• Geomechanics and Engineering
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• v.31 no.3
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• pp.291-304
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• 2022

Maximum shear modulus (G_max or G₀) is an important soil property useful for many engineering applications, such as the analysis of soil-structure interactions, soil stability, liquefaction evaluation, ground deformation and performance of seismic design. In the current study, bender element (BE) tests are used to evaluate the effect of the void ratio, effective confining pressure, grading characteristics (D₅₀, C_u and C_c), anisotropic consolidation and initial fabric anisotropy produced during specimen preparation on the G_max of sand-gravel mixtures. Based on the tests results, an empirical equation is proposed to predict G_max in granular soils, evaluated by the experimental data. The artificial neural network (ANN) and Adaptive Neuro Fuzzy Inference System (ANFIS) models were also applied. Coefficient of determination (R²) and Root Mean Square Error (RMSE) between predicted and measured values of G_max were calculated for the empirical equation, ANN and ANFIS. The results indicate that all methods accuracy is high; however, ANFIS achieves the highest accuracy amongst the presented methods.

• Computers and Concrete
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• v.33 no.3
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• pp.275-284
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• 2024

This work presents a comprehensive investigation of buckling behavior of bidirectional functionally graded imperfect beams exposed to several thermal loading with general boundary conditions. The nonlinear governing equations are derived based on 2D shear deformation theory together with Von Karman strain-displacement relation. The beams are composed of two different materials. Its properties are porosity-dependent and are continuously distributed over the length and thickness of the beams following a defined law. The resulting equations are solved analytically in order to determine the thermal buckling characteristics of BDFG porous beams. The precision of the current solution and its accuracy have been proven by comparison with works previously published. Numerical examples are presented to explore the effects of the thermal loading, the elastic foundation parameters, the porosity distribution, the grading indexes and others factors on the nonlinear thermal buckling of bidirectional FG beam rested on elastic foundation.