• Title/Summary/Keyword: 2D/E

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Skin Safety Evaluation of Pectin Lyase-modified Red Ginseng Extract (GS-E3D) (홍삼가수분해농축액(GS-E3D)의 피부 안전성 평가)

  • Pyo, Mi Kyung;Lee, Gyeong Hee;Cha, Seon Woo;Park, Ki Young;Lee, Ki Moo
    • Korean Journal of Pharmacognosy
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    • v.49 no.3
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    • pp.246-254
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    • 2018
  • Pectin lyase-modified red ginseng extract (GS-E3D) is a newly developed ginsenoside Rd-enriched ginseng extract. This study was designed to investigate the skin safety of GS-E3D. Single oral toxicity, single dermal toxicity, bovine corneal opacity and permeability (BCOP) assay, skin irritation test with $SkinEthic^{TM}$ human epidermis model, skin sensitization local lymph node assay, and human patch test, were examined. The oral and dermal $LD_{50}$ value of GS-E3D was over 2,000 mg/kg in rats. GS-E3D was identified as a non-irritant to skin in BCOP assay, human epidermis models, and patch test from the 32 human subjects. The skin sensitization potential of GS-E3D was less than 25% in local lymph node assay. These results indicate that GS-E3D can be used as a safe ingredient without adverse effects in various skin care products.

Valence Band Photoemission Study of Co/Pd Multilayer (광전자분광법을 이용한 Co/Pd 다층박막의 전자구조연구)

  • Kang, J.-S.;Kim, S.K.;Jeong, J.I.;Hong, J.H.;Lee, Y.P.;Shin, H.J.;Olson, C.G.
    • Journal of the Korean Magnetics Society
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    • v.3 no.1
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    • pp.48-55
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    • 1993
  • We report the photoemission (PES) studies for the Co/Pd multilayter. The Co 3d PES spectrum of Co/Pd exhibits two interesting features, one near the Fermi energy, $E_{F}$, and another at ~2.5 eV below $E_{F}$. The Co 3d peak near $E_{F}$ of Co/Pd is much narrower than that of the bulk Co, consistent with the enhanced Co magnetic moment in Co/Pd compared to that in the bulk Co. The Co 3d feature at ~-2.5 eV resembles the Pd valence band structures, which suggests a substantial hybridization between the Co and Pd sublayers. The Co 3d PES spectrum of Co/Pd is compared with the existing band structures, obtained using the local spin density functional calculations. A reasonable agreement is found concerning the bandwidth of the occupied part of the Co 3d band, whereas a narrow Co 3d peak near $E_{F}$ seems not to be described by the band structure calculations.

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Growth and Yield of Strawberry $(Fragaria\;\times\;ananassa\;Duchesne)$ 'Nyoho' and Salt Accumulation in PE Film House Soil as Affected by Fertilization Program (시비방법이 무기염의 토양집적과 딸기 생육 및 수량에 미치는 영향)

  • Jung Suck Kee;Choi Jong Myung;Lee Young Bok
    • Journal of Bio-Environment Control
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    • v.14 no.1
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    • pp.38-45
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    • 2005
  • This research was conducted to determine the effect of fertilization programs on crop growth, nutrient uptake and yield of strawberry and salt accumulation in PE film house soil. To achieve these, experiments were conducted through two years with various fertilization program such as traditional fertilization(A), recommended fertilization of Rural development administration (B), Tochigi prefectural experiment station (C) and Nonsan strawberry experiment station (D), and control (E). In 1st year, statistical differences in growth characteristics were not observed among treatments except (E). Yield per 10 was the highest in (D) followed by (A), (B), (C) and (E) and there was the statistical difference between (D) and (E). In the 2nd year experiment, growth characteristics and yield showed similar trends to those of 1st year experiment. In the results of soil analysis of 2nd year, the soil pH of all treatments were in the acceptable range, while electrical conductivity of (A) and (D) were 2.36 and 2.19 %$dS{\cdot}m^{-1}$, respectively. After finishing of strawberry cultivation, nitrate concentration in soil solution of (A) and (D) were 74.6 and 65.0%$mg{\cdot}L^{-1}$ and Na in those were 3.71 and 3.53 $cmol+kg^{-1}$, respectively. Above results indicated that (A) and (D) were good fertilization program for strawberry cultivation, but those also resulted in accumulation of $NO_{3-}N$ and Na in PE house soil.

Species Diversity Analysis of the Aquatic Insect in Paddy Soil

  • Eom, Ki-Cheol;Han, Min-Soo;Lee, Byung-Kook;Eom, Ho-Yong
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.3
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    • pp.163-172
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    • 2013
  • The aquatic insect collected at six areas (each 2 for mountain area, plain field, and urban area) from 2009 to 2011 were classified to analyze the distribution and diversity of species. Frequency (number of aquatic insect: N), number of species (S), similarity index (C), richness index (R1, R2), variety index (V1, V2), evenness index (E1, E2, E3, E4, E5), and dominance index (D1) were investigated. Total N and S were 143 and 84, respectively. C matrix of 153 combinations was constructed with the average of 0.542. The average C of 3 years (0.659) was 9.9% P, more higher than the average C of 6 areas (0.560). The average values of the index of 18 plots were 2.28, 0.17, 1.24, 1.08, 0.07, 0.06, 0.01, 0.87, 0.31, 0.93 for R1, R2, V1, V2, E1, E2, E3, E4, E5, D1, respectively. The order in the coefficient of variation (CV) of the indicator for 18 plots was N (70.0%) > E3 (54.9%) > E1 (49.6%) > R2 (40.5%) > S (35.3%) > R1 (33.7%) > E2 (28.4%) > E5 (15.9%) > V1 (11.1%) > E4 (6.3%) > V2 (5.1%) > D1 (4.8%). The correlation matrix with 66 combinations between the indexes was constructed with statistical significance for 33 combinations. However, R1, V1, E2 and D1 were the proper indexes to represent species diversity of aquatic insect based on the correlation matrix and the theory of statistical independence. The richness index was highest in mountain, variety index in urban area, and evenness index in plain field. However, the dominance index was lowest in urban area.

Performance Analysis of Multicarrier CDMA System with Adaptive Modulators in Rayleigh Fading Channel (레일레이 페이딩 환경하에서 적응형 변조기를 적용한 다중 반송파 CDMA 시스템의 성능 분석)

  • Lee, Kwang-Hee;Kim, Hang-Rae;Han, Tae-Young;Kim, Nam
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.12
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    • pp.1300-1310
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    • 2003
  • In this paper, the performance of a multicarrier CDMA system using adaptive modulation and adaptive subchannel allocation scheme is analyzed in Rayleigh fading channel. The proposed adaptive modulator consists of modulation schemes using QPSK 16 QAM, 64 QAM and 256 QAM and constellations are pointed by Gray code. In addition, the threshold of the analysis is average E$\_$b//N$\_$o/ when the BER is 1 %. In the multicarrier system with adaptive subchannel allocation scheme, each DS waveform of user is transmitted over the K subchannels with the biggest fading among L subchannels. In case of the proposed system, total 4 subchannels are used and data are transmitted over 2 subchannels with the biggest fading, which results in the threshold of each channels is 5.2 dB, 9 dB, 13.2 dB and 8.4 dB, 12.2 dB, 16.3 dB. In the case of proposed system, the BER of 10$\^$-3/ is satisfied if average E$\_$b//N$\_$o/ is 8.1 dB. This is increased performance of 12.9 dB in comparison with conventional system. The BPS according to average channel is needed average E$\_$b//N$\_$o/ of about 15 dB in 7 bit. In the case of subchannel error, the BER of 10$\^$-3/ is 13.6 dB and is declined about 5.5 dB.

The Effects of Fat-soluble Vitamin Administration on Plasma Vitamin Status of Nursing Pigs Differ When Provided by Oral Administration or Injection

  • Jang, Y.D.;Lindemann, M.D.;Monegue, H.J.;Stuart, R.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.5
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    • pp.674-682
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    • 2014
  • Four experiments were conducted to investigate the effect of fat-soluble vitamin administration to sows or newborn pigs on plasma vitamin status. In Exp. 1 and 2, a total of 24 and 43 newborn pigs were allotted to control and vitamin treatments (vitamin $D_3$ with variable addition of vitamins A and E) orally or by i.m. injection. In Exp. 3, pigs from Exp. 2 were allotted to 2 treatments (${\alpha}$vitamins $D_3$ and E in drinking water) for 14 d postweaning. In Exp. 4, twenty-four gestating sows were used for 2 treatments (${\pm}injection$ of a vitamin $D_3$/A/E product 2 wk prepartum). In Exp. 1 and 2, when vitamin $D_3$ was administrated orally or by i.m. injection on d 1 of age, pigs had increased plasma 25-hydroxycholecalciferol (25-OH $D_3$) concentration 10 d after administration compared with control pigs (p<0.05). The injectable administration with vitamin $D_3$ and E was able to achieve higher plasma 25-OH $D_3$ (p<0.05) and ${\alpha}$-tocopherol (p<0.05) concentrations than oral administration. At weaning, the pigs in the injection group had higher plasma 25-OH $D_3$ concentration than those in the other groups in both studies (p<0.05). In Exp. 3, water supplementation of vitamin $D_3$ and E postweaning increased plasma 25-OH $D_3$ and ${\alpha}$-tocopherol concentrations at d 14 postweaning (p<0.01). In Exp. 4, when sows were injected with the vitamin $D_3$ product prepartum, serum 25-OH $D_3$ concentrations of sows at farrowing (p<0.01), and in their progeny at birth (p<0.01) and weaning (p<0.05) were increased. These results demonstrated that fat-soluble vitamin administration to newborn pigs increased plasma 25-OH $D_3$ concentration regardless of administration routes and ${\alpha}$-tocopherol concentration by the injectable route, and that water supplementation of vitamin $D_3$ and E to nursery pigs increased plasma 25-OH $D_3$ and ${\alpha}$-tocopherol concentrations. Additionally, injecting sows with vitamin $D_3$ prepartum increased 25-OH $D_3$ in sows and their offspring. If continued research demonstrates that the serum levels of 25-OH $D_3$ are critical in weanling pigs, a variety of means to increase those levels are available to swine producers.

A Compact Metamaterial Chip Antenna with Ground Coupling Structure for Bluetooth Application (Ground Coupling 구조를 이용한 초소형 Metamaterial Bluetooth 칩 안테나)

  • Park, Young-Hwan;Lee, Kang-Hee;Ji, Jeong-Keun;Ryu, Ji-Woong;Kim, Gi-Ho;Seong, Won-Mo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.9
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    • pp.930-935
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    • 2009
  • This paper describes a miniaturezed metamaterial BT chip antenna for mobile devices. The size of the proposed antenna is $3.0\;mm(W){\times}2.0\;mm(L){\times}1.2\;mm(H)$. And it is fabricated by chip type. The zeroth-order resonant properties are analyzed by magnitude and phase distributions of the surface current using surface current scanning system. The antenna offers omni-directional radiation patterns and measured 3D average gain is over - 1.7 dBi.

NOTE ON THE PINNED DISTANCE PROBLEM OVER FINITE FIELDS

  • Koh, Doowon
    • Journal of the Chungcheong Mathematical Society
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    • v.35 no.3
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    • pp.227-234
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    • 2022
  • Let 𝔽q be a finite field with odd q elements. In this article, we prove that if E ⊆ 𝔽dq, d ≥ 2, and |E| ≥ q, then there exists a set Y ⊆ 𝔽dq with |Y| ~ qd such that for all y ∈ Y, the number of distances between the point y and the set E is ~ q. As a corollary, we obtain that for each set E ⊆ 𝔽dq with |E| ≥ q, there exists a set Y ⊆ 𝔽dq with |Y| ~ qd so that any set E ∪ {y} with y ∈ Y determines a positive proportion of all possible distances. The averaging argument and the pigeonhole principle play a crucial role in proving our results.

Interactions between Estradiol-17 ${\beta}-BSA$ and Calcitropic Hormones in $Ca^{2+}$ Uptake in Renal Proximal Tubule Cells

  • Han, Ho-Jae;Lee, Yeun-Hee;Seo, Eun-Ju
    • The Korean Journal of Physiology and Pharmacology
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    • v.6 no.5
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    • pp.261-267
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    • 2002
  • The aim of the present study was to investigate the interaction of $estradiol-17{\beta}-bovine$ serum albumin $(E_2-BSA)$ and calcitropic hormones, such as parathyroid hormone, calcitonin, and vitamin D, in regulation of $Ca^{2+}$ uptake in primary cultured renal proximal tubule cells. Statistically significant increase in $Ca^{2+}$ uptake was found from 2 hours after $(E_2-BSA)\;(10^{-9}\;M)$ treatment, while $estradiol-17{\beta}\;(10^{-9}\;M)$ did not affect. Treatment of the cells with $(E_2-BSA)\;(10^{-9}\;M)$ together with parathyroid hormone (PTH) $(10^{-8}\;M),$ vitamin D $(10^{-8}\;M),$ or calcitonin $(10^{-8}\;M)$ significantly stimulated $Ca^{2+}$ uptake by 32.50%, 29.30%, or 27.75%, respectively, compared with the control. However, calcitropic hormones did not exhibit any synergistic effect on the E2-BSA-induced stimulation. $E_2-BSA$ significantly increased cAMP generation and PKC activity. The stimulatory effect of cotreatment of $E_2-BSA$ and PTH or vitamin D was blocked by SQ22536 (an adenylate cyclase inhibitor) and staurosporine (a PKC inhibitor), but the effect of cotreatment of $E_2-BSA$ and calcitonin was not blocked. Furthermore, 8-Br-cAMP and TPA (an artificial PKC promoter) increased $Ca^{2+}$ uptake by 25.51% and 16.47%, respectively, compared with the control. In conclusion, $E_2-BSA$ combined with calcitropic hormones regulated $Ca^{2+}$ uptake partially via cAMP and PKC-dependent mechanisms in renal proximal tubule cells.

Improved Hypophysectomy Technique by Sublaryngeal A, pp.oach and the Efficacy of bGH in Hypophysectomized Female Rats (흰쥐에서 후두하경로를 통한 하수체 적출술의 개량과 하수체 적출 흰쥐를 이용한 bGH 효능시험)

  • 정영채;김창근;이종완;나광빈;김광식;박선애;유영아;이세영
    • Korean Journal of Animal Reproduction
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    • v.21 no.2
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    • pp.197-205
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    • 1997
  • Improved hypophysectomy technique and the efficacy of bGH in hypophysectomized female rats were studied as a basis for the function of endocrine gland and hormones. 1. With improved sublaryngeal a, pp.oach by hypophysectomy, 34 rats out of 40 were successfully hypophysectomized(more than 80% of success). The surgical time for hypophysectomy per rat was taken about 3.0$\pm$1.0 min. 2. For the effect of hypophysectomy and bGH on body weight gain among the 5 gruops of A, B, C, D, and E, the weight gains for A, B, C, D, and E, were 93g, 9.2g, 10.7g, 25.1g and 36.2g, respectively, which implied that hypophysectomy had a major effect on body weight. And also, the effect of bGH was paralleled with the level of bGH. There were significant difference between control and hypophysectomized groups, and between the bGH treated and bGH non-treated groups after hypophysectomy(p<0.01). 3. For the effect of hypophysectomy and bGH on the length of femur, tibia, humerus, and anterbrachi, longest was for A, shortest for B, and longer in order of C, D, and E. The A group was significantly longer than B, C, D, and E groups. The B group was shorter than C, D, and E groups(p<0.01). 4. For the effect of hypophysectomy and bGH on the weight of femur, tibia, humerus, and antebrachi, heaviest was for A, lightest for B, and heavier in order of C, D, and E. The A group was significantly heavier than B, C, D, and E groups. The B group was lighter than C, D, and E groups(p<0.01). 5. In changes of body length, and weights of liver and heart, A group was most drastically increased. Among the hypophysectomized groups, the change was increased in order of B, C, D, and E. Especially, the change of A group was significantly greater than B, C, D and E gruops. However, no significant differences were found among B, C, D, and E groups. 6. The hypophysectomy in rat had a significant effect on body growth. The effect of hormone was remarkably different depending upon the level of hormone. It was found that 300$\mu\textrm{g}$ of bGH/kg of body wt/day was slightly lower for normal growth.

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