• Journal of Chest Surgery
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• 제20권2호
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• pp.384-392
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• 1987

The occlusive coronary artery disease presents a potential threat to a significant population in the United State. According to many case reports, the increasing incidence of coronary artery disease due to atherosclerosis is noted in Korean, recently. We experienced one case of coronary artery disease. He was a 68 year old male who had been suffered from hypertension since 1 5 years ago, and had intermittent conservative treatment at local clinic. He had been afflicted with severe chest pain on exertion, but this symptom was relieved on rest. Pre-operative EKG finding revealed no any other ischemic sign. Significant S-T segment depression was noted at lead II, aVF, V3, V4, and V5, and inverted T wave in V5 and V6 after Master`s test. Simple chest X-ray finding showed emphysematous field, bilaterally. Final pre-operative diagnosis was made by coronary angiogram, which showed almost 90% degree of occlusive lesion in the proximal part of left main coronary artery above the origin LAD artery. He was treated successfully by aorta-coronary saphenous vein graft under extra-corporeal circulation in May, 1987. He has been followed up with uneventful course.

• 복식문화연구
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• 제6권2호
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• pp.109-126
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• 1998

The purpose of this study was to analyze the expressional characteristics of the machine aesthetics in the fashion design. First, this study was started from analyzing mechanical beauty represented on the early 20th century art style. Machine aesthetics has influenced on the art and fashion design from modern to now. Futurism was grounded in the complete renewal of human sensibility brought about by the great discoveries of science. Especially, Russia avant-garde was inspired by the Futurism, that is Rayonism, Constructivism, Suprematism. Kasimir Malevich moved on immediately to purely abstract paintings of which the first was a black square on a white canvas. He had begun the art he called 'Suprematism'. Malevich's geometry was funded on the straight line, the supremely elemental form which symbolized man's ascendancy over the chaos of nature. The square was the basic suprematist element and was a repudiation of the world of appearances, and of past art. He repudiated any marriage of convenience between the artist and the engineer. Vladimir Tatlin made some of the most revolutionary works of modern art, these were the first works to be called 'construction'. Constructivists believed that the essential conditions of the machine and the consciousness of man inevitably create an aesthetic which would reflect their time. They eulogized simple shapes. That believed that buildings and objects should be freed from the ornamental excrescences and the accumulated barnacles of past art. Consequently, under the theoretical background, the result is as follows. First, The functional formativeness of machine aesthetics was expressed as a geometrical silhouette, construction line, non-ornamental construction, simple color in the 20th century design. Second, The mechanical formativeness of machine aesthetics was expressed as a construction of new material-iron, aluminium, plastic, glass-, geometrical form of material in he 20th century design. That is, machine beauty has more concerned with the expressional ideology of the art style and the formativeness of fashion design by silhouette, construction line, material, form.

• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2003년도 International Symposium of Silkworm/Insect Biotechnology and Annual Meeting of Korea Society of Sericultural Science
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• pp.99-99
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• 2003

Brain-derived neurotrophic factor (BDNF) induced a significant neurite extension of antennal lobe (AL) neurons from the silk moth Bombyx mori in culture on lamini/ concanavalin A-coated dishes, in comparison with smaller effect of 20-hydroxyecdy-sone (20-HE). But the effect fur neurite extension by 5-hydroxytryptamine (5-HT) could not be found. A significant increase in the number of new primary branches from the principal neurites of AL neurons was also shown in culture with BDNF and 5-HT, but not with 20-HE. (omitted)

• Journal of Photoscience
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• 제11권2호
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• pp.55-59
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• 2004

The present investigation is an attempt to create an optimized protocol for a bactericidal modality of different powers of He-Ne laser radiation to eliminate periodontitis disease causing bacteria from dental plaques. Periodontitis is most prevalent infectious disease of men and caused by a limited number of Gram negative oral bacteria. Porphyromonas gingivalis and Streptococcus sanguis are the important bacteria responsible for periodontitis diseases. Effect on periodontitis disease causing bacteria were produced by the exposure of different powers of He-Ne laser light i.e. 9 mW, 17 mW and 26 mW of red colour of wavelength 632.8 nm in two different periods of time i.e. 10 min. and 20 min. in the presence of dye Methylene blue (MB) used as a photosensitizer. The results have been shown in terms of percentage inhibition of colony forming units (cfu.) of bacteria. This study has shown that maximum inhibition of cfu. were observed in Laser+MB-20 min. exposure time. This inhibition was followed by Laser+MB-10 min., but minimum inhibition was seen in Laser only at 10 min. exposure. In case of effect of methylene alone on the cfu. of bacteria, it was seen that MB have not shown more inhibition of cfu. and it had shown that the no. of cfu. are very similar to that of control. The above observation of the present study was seen in case of every 3 different type of used powers of laser for both the bacteria. Maximum percentage inhibition of cfu. were seen in case of 26mW powers of He-Ne laser, which was 67. 28% to 61.42% for Porphyromonas gingivalis and Streptococcus sanguis respectively. So, increasing the power of laser (safe range for dentistry is 3-30 mW) under conditions shows an increased percentage inhibition of cfu. Thus the present investigation may be a useful adjunct with mechanical debridement in the prevention of recolonization of subgingival lesions by pathogenic microorganisms which are harmful and drug resistant.

• 동굴
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• 제79호
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• pp.17-30
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• 2007

난고 김삿갓의 생애 :선생은 안동 김씨의 시조인 고건 개국공신 신평의 후예로 순조 7년(1807년) 3월 13일 경기도 양주군 회천면 회암리에서 부 안근과 모 함평 이씨 사이의 2남으로 출생하였고, 본명은 병연(炳淵)이고 자는 성심(性深) 호는 난고(蘭皐) 별호는 김삿갓 또는 김립(金笠)이다. 순조 11년(1811년) "홍경래의 난"이 일어났을 때 조부 김익순이 선천부사로 있으면서 홍경래에게 항복, 역적으로 몰려 폐족처분을 받아 가족이 영월로 옮겨와 은둔생활을 하였다. 이러한 생활 속에서도 모친은 자식에게 조부의 사연을 감추고 글을 가르쳤으며, 20세 되던 해 영월 동헌에서 백일장에 응시하여 조부를 비판하는 글로 장원이 되었다. 그 후에 조부라는 사실을 알고 자책과 통한을 이기지 못하여 22세에 집을 나서 방랑생활을 하면서 서민들의 애환을 시로 읊어 서민문학의 큰 틀을 마련하였다. 1863년 전라남도 화순군 동복에서 작고하여 그곳에 묘를 썼으며, 3년 후 둘째 아들 익균이 지금의 묘로 옮겨 모셨다. (난고선생 묘 옆에 서있는 안내문에서)

• 대한본초학회지
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• 제20권4호
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• pp.69-76
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• 2005

Objectives : HERBA EPHEDRAE (HE) has been used cough and asthma for long time in korea. In the present study, we examined the effect HE on the ovalbumin (OVA)-induced airway hyper-reactivity (AHR). Methods : To examine the effect of HE on AHR, mice were sensitized with 100 mg of OVA and 1mg of alum intraperitoneally on day 0 and 14. On day 28, mice were challenged on 3 consecutive days with 3% OVA and AHR was assessed 24 h after the last challenge. To examine severity of airway hyper-reactivity, we examined eosinophil population and cytokine production in bronchoaveloar lavage fluid(BALF) and stained with hematoxylin and eosin in lung. Results : HE potently inhibited the development of airway hyper-reactivity and also reduced the number of eosinophil during OVA-induced airway hyper-reactivity. HE also inhibited cytokines production such as IL-4, IL-5, IL-13 in BALF. Furthermore, HE inhibited proliferation of eosinophil in a dose dependent manner. Conclusions : These results suggest that HE may be beneficial oriental medicine for AHR.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4545-4548
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• 2013

The objective of this study is to assess tissue expression of CA-125 and HE4 protein in primary benign and malignant epithelial tumours of the ovary and correlate with serum CA-125 levels. A total of 100 formalin-fixed, paraffin embedded sections of ovarian tumours which included serous adenoma (11), mucinous adenoma (42), serous carcinoma (20), mucinous carcinoma (12) and endometrioid carcinoma (15), histologically diagnosed between $1^{st}$ January 2004 to $31^{st}$ December 2012 at the University Malaya Medical Centre, were stained for HE4 (rabbit polyclonal antibody, Abcam, UK) and CA-125 (mouse monoclonal antibody clone: OC125, Cell Marque Corporation, Rocklin, California, USA). Pre-operative serum CA-125 levels were obtained from the laboratory information system. Immunoscore (I score) for HE4 and CA-125 was given based on the intensity of staining and percentage of positive tumour cells and considered significant when it was >50 (intensity of staining multiplied by percentage of positive tumour cells). Serum CA-125 levels were compared with the I score of HE4 and CA-125 in tissues. We noted that the CA-125 levels in serum and tissues were significantly raised in malignant compared to benign ovarian tumours (p value<0.05). Tissue expression of HE4 protein was also significantly raised in malignant tumours compared to benign tumours (p value<0.05). We conclude that HE4 can be a useful tissue immunomarker in addition to CA-125.

• 한국응용곤충학회지
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• 제46권1호
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• pp.147-151
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• 2007

한국산 곤충병원성 선충 S. carpocapsae GSN1 계통(ScG), S. glaseri Dongrae 계통(SgD), Heterorhabditis bacteriophora Hamyang 계통(HbH) 및 Heterorhabditis spp. Cyeongsan 계통(HeG)에 대한 알팔파바구미의 감수성을 실내 페트리디쉬 검정하였다. 알팔파바구미의 유충 치사율은 선충 종과 처리농도에 따라 유의적인 차이가 있었다. 알팔파바구니의 유충 한 마리당 각 선충 계통의 감염충(3령충)을 20마리 이상 접종했을 때 3일 후 77.5(HbH)-100(SgD)의 높은 치사율을 나타내었다. 선충의 침입수는 선충 종과 처리농도에 따라 차이가 있었으나, 증식수는 유의적 인 차이가 없었다. 침 입수에서는 SgD를 알팔파바구미 유충 한 마리당 80마리로 접종했을 때 30.2마리로 가장 많았다. 그리고 증식수는 HeG를 알팔파바구미 유충 한 마리당 80마리로 접종했을 때 2,671.5로 가장 많았다. 한국산 곤충병원성 선충 4 계통은 알팔파바구미의 성충에는 전혀 기생하지 않았으나 노숙 유충에 대해서는 매우 감수성이었다.

• 생명과학회지
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• 제32권12호
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• pp.938-946
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• 2022

본 연구는 대풍자 에탄올 추출물에 대한 항산화 활성 및 주름생성 억제 활성을 확인하고자 하였다. 대풍자 에탄올 추출물의 항산화 활성을 확인하기 위하여 DPPH와 ABTS⁺ radical 소거능을 측정하였고 그 결과 추출물 1,000 ㎍/ml 농도에서 각각 73.5%와 74.4%의 높은 소거능을 나타냈다. 주름생성 억제 활성을 확인하기 위하여 collagenase 저해 활성을 실험하였으며, 그 결과 추출물 1,000 ㎍/ml 농도에서 78.8%의 유의할만한 우수한 결과를 보였다. 또한 추출물에 대한 세포의 독성을 확인하기 위해 MTT assay를 수행하였으며, 50 ㎍/ml 이하의 농도에서 약 91.7%의 생존율을 보여, 이후의 세포 실험은 50 ㎍/ml 이하의 농도에서 진행하였다. 섬유아세포인 CCD-986sk에 UVB (20 mJ/cm²)의 자극을 주고 대풍자 에탄올 추출물을 농도별로 처치한 후 procollagen type I과 MMP-1의 발현에 대한 영향을 확인하고자 ELISA 및 RT-PCR 분석을 하였다. 그 결과 대풍자 에탄올 추출물은 PIP의 생합성과 mRNA 발현은 농도의존적으로 증가하였으며, 특히 UVB만 자극한 Cont (각각의 생합성율은 50.3%와 45.8%)과 비교하였을 때 50 ㎍/ml의 농도에서 각각 약 64.2%와 83.4%의 생합성을 보였다. MMP-1의 protein과 mRNA 발현에 대한 결과는 농도의존적으로 감소했음을 확인하였으며, 50 ㎍/ml의 농도에서 각각 약 48.7%와 35.9%의 낮은 발현율을 보였다. 이와 같은 결과를 바탕으로 본 연구는 대풍자 에탄올 추출물이 주름억제 기능성 소재로써의 활용 가능성을 제시해 줄 것으로 사료된다.

• 한국실내디자인학회논문집
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• 제20권6호
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• pp.97-104
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• 2011

Art has always been a witness to its time. The art of our century has lived through two world war. In that time Friedensreich Hundertwasser was born to a half Jewish family in Vienna in 1928. He lived and died as a painter, architect, designer, ecologist, writer, innovator... etc. He was impressed form Gustav Klimt, who pioneered the Viennese Secession which was the Austrian expression of the Art-Nouveau mouvement and inspired by the works of Egon Schiele from an early date. His style as an architect was heavily influenced by Antonio Gaudi and some of the Jugendstil architects. Although his architectural work is comparable to Gaudi in its biomorphic forms and use of tile, but is currently renowned for his unique styling. His character as follows; First, Bold color - His use of color is bold, and he has a strong sense of which color work well together. Second, Curved line & Spiral - It's the primary shapes in his works against the tyranny of ugliness and the iron rule of its straight line. Spiral reveal as a transautomaism. Third, Harmony with nature - His work is the creator of beauty, of nature of harmony, peace of joy, against the contradictions of our post-industrial society. He represented these various characteristics in his works. Hundertwasser first achieved notoriety for his boldly-colored painting, he is more widely renowned today for his revolutionary architectural designs.