• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4117-4123
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• 2016

Background: Methylation of promoter 2 of the SHP1 gene is epithelial cell specific, with reported potential as a lymph node metastatic marker. Objective: To demonstrate SHP1-P2 methylation-specific quantitative PCR effectiveness in detecting colorectal cancer (CRC) DNA in lymph nodes. Materials and Methods: SHP1-P2 methylation levels were measured in lymph nodes of CRC patients and compared with pathological findings and patient prognosis. Results: Lymph nodes of CRC metastatic patients without microscopically detectable cancer cells had higher SHP1-P2 methylation levels than lymph nodes of controls (p<0.001). In addition, a higher SHP1-P2 methylation level was associated with a shorter duration until adverse disease events, metastasis, recurrence and death (r2 = 0.236 and p value = 0.048). Studying two cohorts of 74 CRC patients without microscopic lymph node metastases showed that only the cohort containing samples with high SHP1-P2 methylation levels had a significant hazard ratio of 3.8 (95%CI = 1.02 to 14.2). Conclusions: SHP1-P2 methylation PCR can detect CRC DNA in lymph nodes even if cancer cells are not visible under a microscope, confirming applicability as a potential universal lymph node metastatic marker.

• Journal of Korea Spatial Information System Society
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• v.4 no.2 s.8
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• pp.23-34
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• 2002

Various tries are in progress to expand the usability of wireless telecommunication harminized internet technology. The most typical example among those services is LBS(Location Based Service). Nowaday, Standards for telecommunication system of LBS centers round on 3GPP(3rd Generation Partnership Project) and 3GPP2. In this paper we compare the telecommunication system of 3GPP and 3GPP2 in order to make domestic standards of telecommunication system to provide LBS. First, we investigate network models and interfaces of GSM(Global System for Mobile) and ANSI(America National Standard Institute)-41/PCS1900 - Telecommunication type of 2nd generation. Also we consider those of UMTS (Universal Mobile Telecommunication System) and cdma2000 - Telecommunication type of 3nd generation. Then we analysis function components for LBS of each network models details.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.9
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• pp.279-286
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• 2012

Recently, design of Universal Soft Controller(USC) has been applied to the advanced control room for nuclear power plant. USC is software-based manual control means to control safety components as well as non-safety components in the highly-integrated control room. Therefore, design feature of USC is essential for the implementation of a single workstation in the advanced control room. The traditional control room is replaced by computer-driven consolidated operator interfaces. Considering our design has further reduced the probability of USC spurious signals by requiring two distinct operator control actions to generate any control signal. The reality of USC does not increase the probability of reactor trip because the probability of spurious USC signal is negligible. Universal Soft Control represents a significant evolution in nuclear I&C/HSI System. USC integrates the indicators and controls from multiple divisions into a single integrated visual display unit(VDU) based HSI(Human System Interface). In order to prevent adverse influence on safety function performance from USC failure, ESFAS signals are applied to safety components or functions. In addition, safety manual switches have priority over USC's signals. Therefore, spurious USC signals can be momentarily blocked by selecting a soft control command from the safety VDU.

• Proceedings of the Korea Contents Association Conference
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• 2004.11a
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• pp.327-332
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• 2004

USB(Universal Serial Bus) is one of the most popular communication interfaces. When USB is used in an extended range, especially configurating In-home network by connecting multiple digital devices each other, USB interface uses the bandwidth in the way of TDM(Time Division Multiplexing) so that the bottleneck of bus bandwidth can be brought. In this paper, the more effective usage of bus bandwidth to overcome this situation is introduced. Basically, in order to realize the system for transferring realtime moving picture data among digital information devices, we analyze USB transfer types and Descriptors and introduce the method to upgrade detailed performance of Isochronous transfer that is one of USB transfer types. In the case that Configuration descriptor of a device has Interface descriptor that has two AlternateSetting, if Isochronous transfers are not processed smoothly due to excessive bus traffic, the application of the device changes AlternateSetting of the Interface descriptor and requires a new configuration by SetInterface() request. As a result of this adaptive configuration, the least data frame rate is guaranteed to a device that the sufficient bandwidth is not alloted. And if the bus traffic is normal, the algorithm to return to the original AlteranteSetting is introduced. this introduced method resolve the bottleneck of moving picture transfer that can occur in home network connected by multiple digital devices.

• The Journal of the Korea Contents Association
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• v.19 no.4
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• pp.466-476
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• 2019

This study suggested a way to compose a flexible environment capable of meeting the needs of various users from the aged people to challenged people, and ordinary people by applying the concept of universal design. The purpose of this study was to develop a more convenient environment by deriving the best size and color for each subject and constructing a detailed design platform for each module. For this, the concept of universal design as well as the current bathroom designs were examined and various users were analyzed prior to developing the design. A virtual environment was prepared based on the results and its usability was evaluated in two phases with various users including the aged people, challenged people, and ordinary people. As a result, it received quite a favorable evaluation from users, over 90 out of 100 in average, which can be regarded as a proof that it is differentiated from existing bathrooms. This study may lead to the change in the paradigm of bathroom in residential space, development of safer and comfortable domestic environment, and the enhancement of the quality of healthy life through the development of a design platform for each module that provides new experiences to various users. It is hoped that these modular systems are continuously studied not only for bathrooms but also for various residential spaces where people can stay.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.2
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• pp.1-14
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• 2012

The purpose of this study is to derive a desirable riverfront construction plan to me for the activities of citizens through the evaluation and analysis of the urban riverfront space from the perspective of universal design. Therefore, previous studies were examined in order to induce evaluation tools that bhve been grafted from the universal design concept; in addition, a field survey was conducted in Shincheon, Daegu, which was selected as the study target, in order to induce problems and improvement directions from the perspective of universal design. The major results can be summarized as follows. (1) In the 'fairness' aspect, all the items such as installation of integrated functional signage, showing pictures, symbols, foreign language signs, and restroom entrances signage were determined to be 'All Unsuitable' for all sections; and therefore, it is necessary to improve the fairness of usage for everybody. (2) In the 'Functionality(Usability)' aspect, all items such as installation of bicycle paths beside access roads, installation of integrated functional signs, and night light signs were determined to be 'All Unsuitable' for all sections; therefore, it is necessary to improve the functionalities of these facilities. (3) In the 'Convenience' aspect, all items such as the installation of bicycle parking areas, continuous rest facilities, and back and ann support(handles) at resting facilities were determined to be 'All Unsuitable' for many sections; therefore, it is necessary to improve these facilities for the convenience of usage. (4) In the 'Information(Recognizability)' aspect, all items such as showing pictures, symbols, foreign languages and installation of night light signs, and restroom entrances signage were determined to be 'All Unsuitable' for all sections; therefore, it is necessary to improve the recognizability to minimize misunderstandings and confusion. (5) In the 'Safety' aspect, all items such as the installation of safe pedestrian paths in parking areas, using anti-slip and shock absorption materials on restroom floors, and the continuous installation of pedestrian paths that are separate from bicycle paths were determined to be 'All Unsuitable' for all sections; therefore, it is necessary to improve the safety to prevent accidents. (6) In the 'Amenity' aspect, access roads, parking areas, hygiene facilities, convenience facilities, and waterside facilities for many sections were determined to be 'All Unsuitable'; therefore, it is necessary to conduct more concentrated hygiene management. (7) In the 'Accessibility(Mobility)' aspect, all items such as the installation of safe pedestrian paths in parking areas, and continuous pedestrian paths that are separate from bicycle paths were determined to be 'All Unsuitable' for all sections; therefore, it is necessary to improve the accessibility to provide safety and convenience. (8) In the 'Durability' aspect, access roads, parking areas, rest facilities, convenience facilities, fitness facilities, and waterside facilities were determined to be 'All Unsuitable' for many sections, therefore, it is necessary to improve sunken or damaged areas by inspecting facilities by section.

• Journal of the korean academy of Pediatric Dentistry
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• v.45 no.4
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• pp.436-444
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• 2018

The purpose of this study was to compare the shear bond strengths of 3-in-1 flowable composite to the enamel and dentin of primary teeth to previous adhesive systems. 110 primary incisors were prepared and divided into two groups: Dentin group included 5 groups: 1) Scotch bond Multi-purpose plus(DSM), 2) Single-bond 2(DSB), 3) Clearfil SE bond(DSE), 4) All bond universal(DAB), 5) Constic(DC), and Enamel group included 6 groups: 1) Scotch bond Multi-purpose plus(ESM), 2) Single bond 2(ESB), 3) Clearfil SE bond(ESE), 4) All bond universal(EAB), 5) Constic(EC), 6) Constic with additional etching(ECE). A cylinder of composite was bonded to the prepared surface, and the shear bond strength was measured. In the dentin groups, group DC had significantly lower shear bond strength than group DSE. No significant difference was found between group DC, group DSM, group DSB and group DAB. In the enamel groups, there was no significant difference between group EC, group ESE, and group EAB. This material showed lowest shear bond strength among all tested materials in both enamel and dentin groups, showing insignificant difference with some adhesive systems. Therefore, 3-in-1 flowable composite can be used for primary teeth restoration but further studies are needed.

• Progress in Superconductivity
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• v.7 no.2
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• pp.103-108
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• 2006

We have measured the Hall resistivity (${\rho}_{xy}$) and the longitudinal resistivity (${\rho}_{xy}$) on superconducting $MgB_2$ thin films in extended fields up to 18 T. We found a universal scaling behavior between the Hall resistivity and the longitudinal resistivity, which is independent of the temperature and the magnetic field. At a wide magnetic field region from 1 to 18T, a universal power law of ${\beta}=2.0{\pm}0.1$ in a scaling relation, ${\rho}_{xy}={A{\rho}_{xx}}^{\beta}$, was observed in c-axis-oriented $MgB_2$ thin films. These results can be well interpreted by using recent models.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.2
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• pp.216-219
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• 2016

In this paper, the SIW(Substrate Integrated Waveguide)-based feeding antenna for the application of SDR(Software Defined Radar) is designed and manufactured. It is usually well-known that SIWs are easily integrated on PCB and have low transmission loss toward high powered input signal. Also, it is recommended that SIWs are strongly immunized to Electromagnetic Interferences(EMI). In particular, the manufactured antennas are loaded on the USRP(Universal Software Radio Peripheral) platform and employed to detect target RCS as an experiment in this paper. The operating frequency of the proposed antenna is in ISM(Industrial, Scientific and Medical) band(2.4~2.48 GHz) and the measured gain is over 8 dBi at 2.44 GHz.

• English Language & Literature Teaching
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• no.6
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• pp.35-47
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• 2000

This study questions the validity of Crosslinguistic Influence (CLI) in EFL Learning. A ten-minute grammaticality judgement test involving resumptive pronouns in English relative clauses was given to 15 female subjects. The research results, which were analysed in terns of language transfer and universalist arguments, support the existence of a universal process that guides L2 learning, and some common developmental patterns between the two processes of L1 and L2 learning. Hence, the universalist view should be given at least equal Weight as the CLI approach.